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Volumn 5, Issue , 2014, Pages

MicroRNA-302b augments host defense to bacteria by regulating inflammatory responses via feedback to TLR/IRAK4 circuits

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MICRORNA; MICRORNA 302B; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; DACTINOMYCIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK4 PROTEIN, MOUSE;

EID: 84904053158     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4619     Document Type: Article
Times cited : (89)

References (69)
  • 1
    • 0037108761 scopus 로고    scopus 로고
    • Innate recognition of bacteria by a macrophage cytosolic surveillance pathway
    • O'Riordan, M., Yi, C. H., Gonzales, R., Lee, K. D. & Portnoy, D. A. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl Acad. Sci. USA 99, 13861-13866 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13861-13866
    • O'Riordan, M.1    Yi, C.H.2    Gonzales, R.3    Lee, K.D.4    Portnoy, D.A.5
  • 2
    • 0033031869 scopus 로고    scopus 로고
    • Macrophages and epithelial cells respond differently to the pseudomonas aeruginosa type III secretion system
    • Coburn, J. & Frank, D. W. Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system. Infect. Immun. 67, 3151-3154 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 3151-3154
    • Coburn, J.1    Frank, D.W.2
  • 3
    • 84863259013 scopus 로고    scopus 로고
    • Autophagy plays an essential role in the clearance of pseudomonas aeruginosa by alveolar macrophages
    • Yuan, K. et al. Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages. J. Cell. Sci. 125, 507-515 (2012).
    • (2012) J. Cell. Sci. , vol.125 , pp. 507-515
    • Yuan, K.1
  • 4
    • 79955763337 scopus 로고    scopus 로고
    • Pneumonia due to pseudomonas aeruginosa: Part II: Antimicrobial resistance, pharmacodynamic concepts, and antibiotic therapy
    • Sun, H. Y., Fujitani, S., Quintiliani, R. & Yu, V. L. Pneumonia due to Pseudomonas aeruginosa: part II: antimicrobial resistance, pharmacodynamic concepts, and antibiotic therapy. Chest 139, 1172-1185 (2011).
    • (2011) Chest , vol.139 , pp. 1172-1185
    • Sun, H.Y.1    Fujitani, S.2    Quintiliani, R.3    Yu, V.L.4
  • 5
    • 84879330799 scopus 로고    scopus 로고
    • Innate immune recognition of the microbiota promotes host-microbial symbiosis
    • Chu, H. & Mazmanian, S. K. Innate immune recognition of the microbiota promotes host-microbial symbiosis. Nat. Immunol. 14, 668-675 (2013).
    • (2013) Nat. Immunol. , vol.14 , pp. 668-675
    • Chu, H.1    Mazmanian, S.K.2
  • 6
    • 84876129913 scopus 로고    scopus 로고
    • Innate immune recognition mechanisms and translational opportunities
    • Kumar, H. & Bot, A. Innate immune recognition mechanisms and translational opportunities. Int. Rev. Immunol. 32, 113-115 (2013).
    • (2013) Int. Rev. Immunol. , vol.32 , pp. 113-115
    • Kumar, H.1    Bot, A.2
  • 7
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. The functions of animal microRNAs. Nature 431, 350-355 (2004).
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 8
    • 29144505309 scopus 로고    scopus 로고
    • The widespread impact of mammalian MicroRNAs on mRNA repression and evolution
    • Farh, K. K. et al. The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science 310, 1817-1821 (2005).
    • (2005) Science , vol.310 , pp. 1817-1821
    • Farh, K.K.1
  • 9
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: How many mechanisms?
    • Pillai, R. S., Bhattacharyya, S. N. & Filipowicz, W. Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell. Biol. 17, 118-126 (2007).
    • (2007) Trends Cell. Biol. , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 10
    • 84859632747 scopus 로고    scopus 로고
    • MiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay
    • Djuranovic, S., Nahvi, A. & Green, R. miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science 336, 237-240 (2012).
    • (2012) Science , vol.336 , pp. 237-240
    • Djuranovic, S.1    Nahvi, A.2    Green, R.3
  • 11
    • 84876939170 scopus 로고    scopus 로고
    • The long and short of microRNA
    • Yates, L. A., Norbury, C. J. & Gilbert, R. J. The long and short of microRNA. Cell 153, 516-519 (2013).
    • (2013) Cell , vol.153 , pp. 516-519
    • Yates, L.A.1    Norbury, C.J.2    Gilbert, R.J.3
  • 13
    • 77955963884 scopus 로고    scopus 로고
    • Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
    • Betel, D., Koppal, A., Agius, P., Sander, C. & Leslie, C. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol. 11, R90 (2010).
    • (2010) Genome Biol. , vol.11 , pp. R90
    • Betel, D.1    Koppal, A.2    Agius, P.3    Sander, C.4    Leslie, C.5
  • 14
    • 84863686039 scopus 로고    scopus 로고
    • The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha
    • Zhu, S. et al. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha. Nat. Med. 18, 1077-1086 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 1077-1086
    • Zhu, S.1
  • 15
    • 84875784606 scopus 로고    scopus 로고
    • The emerging role of microRNAs in regulating immune and inflammatory responses in the lung
    • Foster, P. S. et al. The emerging role of microRNAs in regulating immune and inflammatory responses in the lung. Immunol. Rev. 253, 198-215 (2013).
    • (2013) Immunol. Rev. , vol.253 , pp. 198-215
    • Foster, P.S.1
  • 17
    • 78650668809 scopus 로고    scopus 로고
    • MiR-155 and its star-form partner miR-155∗ cooperatively regulate type I interferon production by human plasmacytoid dendritic cells
    • Zhou, H. et al. miR-155 and its star-form partner miR-155∗ cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood 116, 5885-5894 (2010).
    • (2010) Blood , vol.116 , pp. 5885-5894
    • Zhou, H.1
  • 18
    • 71749084011 scopus 로고    scopus 로고
    • MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase
    • Shaked, I. et al. MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity 31, 965-973 (2009).
    • (2009) Immunity , vol.31 , pp. 965-973
    • Shaked, I.1
  • 19
    • 62449173209 scopus 로고    scopus 로고
    • MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
    • Ceppi, M. et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc. Natl Acad. Sci. USA 106, 2735-2740 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 2735-2740
    • Ceppi, M.1
  • 20
    • 79251592866 scopus 로고    scopus 로고
    • Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling
    • Nahid, M. A., Satoh, M. & Chan, E. K. Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J. Immunol. 186, 1723-1734 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 1723-1734
    • Nahid, M.A.1    Satoh, M.2    Chan, E.K.3
  • 21
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov, K. D., Boldin, M. P., Chang, K. J. & Baltimore, D. NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl Acad. Sci. USA 103, 12481-12486 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 22
    • 79958257077 scopus 로고    scopus 로고
    • MiR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
    • Boldin, M. P. et al. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J. Exp. Med. 208, 1189-1201 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 1189-1201
    • Boldin, M.P.1
  • 23
    • 68149165370 scopus 로고    scopus 로고
    • MicroRNA-146a feedback inhibits RIG-I-dependent type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2
    • Hou, J. et al. MicroRNA-146a feedback inhibits RIG-I-dependent type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J. Immunol. 183, 2150-2158 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 2150-2158
    • Hou, J.1
  • 24
    • 84872722692 scopus 로고    scopus 로고
    • Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212
    • Nahid, M. A. et al. Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212. J. Immunol. 190, 1250-1263 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 1250-1263
    • Nahid, M.A.1
  • 26
    • 33750541256 scopus 로고    scopus 로고
    • TLR2 and TLR4 expression during bacterial infections
    • Lorenz, E. TLR2 and TLR4 expression during bacterial infections. Curr. Pharm. Des. 12, 4185-4193 (2006).
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 4185-4193
    • Lorenz, E.1
  • 27
    • 84888331319 scopus 로고    scopus 로고
    • Lyn mitigates mouse airway remodeling by downregulating the TGF-beta3 isoform in house dust mite models
    • Li, G. et al. Lyn mitigates mouse airway remodeling by downregulating the TGF-beta3 isoform in house dust mite models. J. Immunol. 191, 5359-5370 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 5359-5370
    • Li, G.1
  • 28
    • 84862119973 scopus 로고    scopus 로고
    • Caveolin-1 plays a critical role in host immunity against klebsiella pneumoniae by regulating STAT5 and akt activity
    • Guo, Q. et al. Caveolin-1 plays a critical role in host immunity against Klebsiella pneumoniae by regulating STAT5 and Akt activity. Eur. J. Immunol. 42, 1500-1511 (2012).
    • (2012) Eur. J. Immunol. , vol.42 , pp. 1500-1511
    • Guo, Q.1
  • 29
    • 78650883975 scopus 로고    scopus 로고
    • Host DNA repair proteins in response to pseudomonas aeruginosa in lung epithelial cells and in mice
    • Wu, M. et al. Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epithelial cells and in mice. Infect. Immun. 79, 75-87 (2011).
    • (2011) Infect. Immun. , vol.79 , pp. 75-87
    • Wu, M.1
  • 30
    • 34548656855 scopus 로고    scopus 로고
    • Signaling pathways downstream of pattern-recognition receptors and their cross talk
    • Lee, M. S. & Kim, Y. J. Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu. Rev. Biochem. 76, 447-480 (2007).
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 447-480
    • Lee, M.S.1    Kim, Y.J.2
  • 31
    • 84884414160 scopus 로고    scopus 로고
    • Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice
    • e859
    • Yuan, K. et al. Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice. Gastroenterology 145, 853-864 e859 (2013).
    • (2013) Gastroenterology , vol.145 , pp. 853-864
    • Yuan, K.1
  • 32
    • 79959467834 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase in macrophages augments bacterial killing by promoting phagocytosis
    • Manni, M. L. et al. Extracellular superoxide dismutase in macrophages augments bacterial killing by promoting phagocytosis. Am. J. Pathol. 178, 2752-2759 (2011).
    • (2011) Am. J. Pathol. , vol.178 , pp. 2752-2759
    • Manni, M.L.1
  • 33
    • 0035983295 scopus 로고    scopus 로고
    • NF-kappaB family of transcription factors: Central regulators of innate and adaptive immune functions
    • Caamano, J. & Hunter, C. A. NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions. Clin. Microbiol. Rev. 15, 414-429 (2002).
    • (2002) Clin. Microbiol. Rev. , vol.15 , pp. 414-429
    • Caamano, J.1    Hunter, C.A.2
  • 34
    • 14044251458 scopus 로고    scopus 로고
    • Human MicroRNA targets
    • John, B. et al. Human MicroRNA targets. PLoS Biol. 2, e363 (2004).
    • (2004) PLoS Biol. , vol.2 , pp. e363
    • John, B.1
  • 35
    • 34249078495 scopus 로고    scopus 로고
    • A critical role for IRAK4 kinase activity in toll-like receptormediated innate immunity
    • Kim, T. W. et al. A critical role for IRAK4 kinase activity in Toll-like receptormediated innate immunity. J. Exp. Med. 204, 1025-1036 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1025-1036
    • Kim, T.W.1
  • 36
    • 33845508583 scopus 로고    scopus 로고
    • Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: A condition reversed by PKC activation
    • Cuschieri, J., Billigren, J. & Maier, R. V. Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation. J. Leukoc. Biol. 80, 1289-1297 (2006).
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 1289-1297
    • Cuschieri, J.1    Billigren, J.2    Maier, R.V.3
  • 37
    • 20244384395 scopus 로고    scopus 로고
    • Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression
    • Nomura, F. et al. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J. Immunol. 164, 3476-3479 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 3476-3479
    • Nomura, F.1
  • 39
    • 79960595150 scopus 로고    scopus 로고
    • MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis
    • Kurowska-Stolarska, M. et al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc. Natl Acad. Sci. USA 108, 11193-11198 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 11193-11198
    • Kurowska-Stolarska, M.1
  • 40
    • 65249138193 scopus 로고    scopus 로고
    • MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins
    • Tang, Y. et al. MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum. 60, 1065-1075 (2009).
    • (2009) Arthritis Rheum. , vol.60 , pp. 1065-1075
    • Tang, Y.1
  • 41
    • 77956289824 scopus 로고    scopus 로고
    • Toll-like receptors in inflammatory bowel diseases: A decade later
    • Cario, E. Toll-like receptors in inflammatory bowel diseases: a decade later. Inflamm. Bowel Dis. 16, 1583-1597 (2010).
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 1583-1597
    • Cario, E.1
  • 42
    • 0031988082 scopus 로고    scopus 로고
    • Gram-negative and gram-positive bacterial products induce differential cytokine profiles in the brain: Analysis using an integrative molecular-behavioral in vivo model
    • Plata-Salaman, C. R., Ilyin, S. E., Gayle, D. & Flynn, M. C. Gram-negative and gram-positive bacterial products induce differential cytokine profiles in the brain: analysis using an integrative molecular-behavioral in vivo model. Int. J. Mol. Med. 1, 387-397 (1998).
    • (1998) Int. J. Mol. Med. , vol.1 , pp. 387-397
    • Plata-Salaman, C.R.1    Ilyin, S.E.2    Gayle, D.3    Flynn, M.C.4
  • 43
    • 0032734869 scopus 로고    scopus 로고
    • Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass
    • Asimakopoulos, G., Smith, P. L., Ratnatunga, C. P. & Taylor, K. M. Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass. Ann. Thorac. Surg. 68, 1107-1115 (1999).
    • (1999) Ann. Thorac. Surg. , vol.68 , pp. 1107-1115
    • Asimakopoulos, G.1    Smith, P.L.2    Ratnatunga, C.P.3    Taylor, K.M.4
  • 44
    • 84879546850 scopus 로고    scopus 로고
    • Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6
    • Liu, X., Chen, W., Wang, Q., Li, L. & Wang, C. Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6. PLoS Pathog. 9, e1003480 (2013).
    • (2013) PLoS Pathog. , vol.9 , pp. e1003480
    • Liu, X.1    Chen, W.2    Wang, Q.3    Li, L.4    Wang, C.5
  • 45
    • 80052020185 scopus 로고    scopus 로고
    • The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by toll-like receptors
    • Yuk, J. M. et al. The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors. Nat. Immunol. 12, 742-751 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 742-751
    • Yuk, J.M.1
  • 46
    • 46749136412 scopus 로고    scopus 로고
    • When signaling pathways collide: Positive and negative regulation of toll-like receptor signal transduction
    • O'Neill, L. A. When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. Immunity 29, 12-20 (2008).
    • (2008) Immunity , vol.29 , pp. 12-20
    • O'Neill, L.A.1
  • 47
    • 84856301921 scopus 로고    scopus 로고
    • TAK1 negatively regulates NF-kappaB and p38 MAP kinase activation in Gr-1+CD11b+ neutrophils
    • Ajibade, A. A. et al. TAK1 negatively regulates NF-kappaB and p38 MAP kinase activation in Gr-1+CD11b+ neutrophils. Immunity 36, 43-54 (2012).
    • (2012) Immunity , vol.36 , pp. 43-54
    • Ajibade, A.A.1
  • 50
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
    • Lin, S. C., Lo, Y. C. & Wu, H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465, 885-890 (2010).
    • (2010) Nature , vol.465 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 51
    • 0036788753 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
    • Jiang, Z., Ninomiya-Tsuji, J., Qian, Y., Matsumoto, K. & Li, X. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol. Cell Biol. 22, 7158-7167 (2002).
    • (2002) Mol. Cell Biol. , vol.22 , pp. 7158-7167
    • Jiang, Z.1    Ninomiya-Tsuji, J.2    Qian, Y.3    Matsumoto, K.4    Li, X.5
  • 52
    • 0035834672 scopus 로고    scopus 로고
    • IRAKmediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B
    • Qian, Y., Commane, M., Ninomiya-Tsuji, J., Matsumoto, K. & Li, X. IRAKmediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B. J. Biol. Chem. 276, 41661-41667 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 41661-41667
    • Qian, Y.1    Commane, M.2    Ninomiya-Tsuji, J.3    Matsumoto, K.4    Li, X.5
  • 53
    • 0034644474 scopus 로고    scopus 로고
    • Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
    • Deng, L. et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103, 351-361 (2000).
    • (2000) Cell , vol.103 , pp. 351-361
    • Deng, L.1
  • 54
    • 43649107807 scopus 로고    scopus 로고
    • IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses
    • Lye, E., Dhanji, S., Calzascia, T., Elford, A. R. & Ohashi, P. S. IRAK-4 kinase activity is required for IRAK-4-dependent innate and adaptive immune responses. Eur. J. Immunol. 38, 870-876 (2008).
    • (2008) Eur. J. Immunol. , vol.38 , pp. 870-876
    • Lye, E.1    Dhanji, S.2    Calzascia, T.3    Elford, A.R.4    Ohashi, P.S.5
  • 55
    • 79955780736 scopus 로고    scopus 로고
    • Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
    • Subramanyam, D. et al. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat. Biotechnol. 29, 443-448 (2011).
    • (2011) Nat. Biotechnol. , vol.29 , pp. 443-448
    • Subramanyam, D.1
  • 56
    • 84869041413 scopus 로고    scopus 로고
    • Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway
    • Kang, H. et al. Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway. J. Biol. Chem. 287, 38656-38664 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 38656-38664
    • Kang, H.1
  • 57
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang, Y. et al. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat. Genet. 40, 1478-1483 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 1478-1483
    • Wang, Y.1
  • 58
    • 84855685116 scopus 로고    scopus 로고
    • The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network
    • Fareh, M. et al. The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. Cell. Death Differ. 19, 232-244 (2012).
    • (2012) Cell. Death Differ. , vol.19 , pp. 232-244
    • Fareh, M.1
  • 59
    • 52949125268 scopus 로고    scopus 로고
    • Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
    • Lin, S. L. et al. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 14, 2115-2124 (2008).
    • (2008) RNA , vol.14 , pp. 2115-2124
    • Lin, S.L.1
  • 60
    • 78650196632 scopus 로고    scopus 로고
    • Regulation of somatic cell reprogramming through inducible mir-302 expression
    • Lin, S.-L. et al. Regulation of somatic cell reprogramming through inducible mir-302 expression. Nucleic Acids Res. 39, 1054-1065 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. 1054-1065
    • Lin, S.-L.1
  • 61
    • 76249119007 scopus 로고    scopus 로고
    • Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
    • Melton, C., Judson, R. L. & Blelloch, R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463, 621-626 (2010).
    • (2010) Nature , vol.463 , pp. 621-626
    • Melton, C.1    Judson, R.L.2    Blelloch, R.3
  • 62
    • 80052364758 scopus 로고    scopus 로고
    • MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-alpha during TLR4-induced gene reprogramming
    • El Gazzar, M., Church, A., Liu, T. & McCall, C. E. MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-alpha during TLR4-induced gene reprogramming. J. Leukoc. Biol. 90, 509-519 (2011).
    • (2011) J. Leukoc. Biol. , vol.90 , pp. 509-519
    • El Gazzar, M.1    Church, A.2    Liu, T.3    McCall, C.E.4
  • 63
    • 84878062642 scopus 로고    scopus 로고
    • Prostaglandin E2-induced changes in alveolar macrophage scavenger receptor profiles differentially alter phagocytosis of pseudomonas aeruginosa and staphylococcus aureus post-bone marrow transplant
    • Domingo-Gonzalez, R. et al. Prostaglandin E2-induced changes in alveolar macrophage scavenger receptor profiles differentially alter phagocytosis of Pseudomonas aeruginosa and Staphylococcus aureus post-bone marrow transplant. J. Immunol. 190, 5809-5817 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 5809-5817
    • Domingo-Gonzalez, R.1
  • 64
    • 84891079308 scopus 로고    scopus 로고
    • Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice
    • Vergadi, E. et al. Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice. J. Immunol. 192, 394-406 (2014).
    • (2014) J. Immunol. , vol.192 , pp. 394-406
    • Vergadi, E.1
  • 65
    • 33644516891 scopus 로고    scopus 로고
    • Analysis of pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence
    • Kulesekara, H. et al. Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence. Proc. Natl Acad. Sci. USA 103, 2839-2844 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2839-2844
    • Kulesekara, H.1
  • 66
    • 0036182484 scopus 로고    scopus 로고
    • Construction and characterization of a live, attenuated aroA deletion mutant of pseudomonas aeruginosa as a candidate intranasal vaccine
    • Priebe, G. P. et al. Construction and characterization of a live, attenuated aroA deletion mutant of Pseudomonas aeruginosa as a candidate intranasal vaccine. Infect. Immun. 70, 1507-1517 (2002).
    • (2002) Infect. Immun. , vol.70 , pp. 1507-1517
    • Priebe, G.P.1
  • 67
    • 27944510065 scopus 로고    scopus 로고
    • Identification of klebsiella pneumoniae virulence determinants using an intranasal infection model
    • Lawlor, M. S., Hsu, J., Rick, P. D. & Miller, V. L. Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model. Mol. Microbiol. 58, 1054-1073 (2005).
    • (2005) Mol. Microbiol. , vol.58 , pp. 1054-1073
    • Lawlor, M.S.1    Hsu, J.2    Rick, P.D.3    Miller, V.L.4
  • 68
    • 79958760196 scopus 로고    scopus 로고
    • Elevated inflammatory response in caveolin-1-deficient mice with pseudomonas aeruginosa infection is mediated by STAT3 protein and nuclear factor kappaB (NF-kappaB)
    • Yuan, K. et al. Elevated inflammatory response in caveolin-1-deficient mice with Pseudomonas aeruginosa infection is mediated by STAT3 protein and nuclear factor kappaB (NF-kappaB). J. Biol. Chem. 286, 21814-21825 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 21814-21825
    • Yuan, K.1
  • 69
    • 77954138395 scopus 로고    scopus 로고
    • A sensitive non-radioactive northern blot method to detect small RNAs
    • Kim, S. W. et al. A sensitive non-radioactive northern blot method to detect small RNAs. Nucleic Acids Res. 38, e98 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. e98
    • Kim, S.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.