MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming

Journal of Leukocyte Biology

Volumn 90, Issue 3, 2011, Pages 509-519

  Gazzar, Mohamed El ^a   Church, Ashley ^b   Liu, Tiefu ^b   McCall, Charles E ^b,c  

^a East Tennessee State University   (United States)

^b Section of Molecular Medicine   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Inflammation; Macrophages; Sepsis

Indexed keywords

ARGONAUTE 2 PROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; ENDOTOXIN; MICRORNA; MICRORNA 146A; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; CELL LINE; DISEASE MODEL; GENE CONTROL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SEPSIS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; ENDOTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; HETEROCHROMATIN; HISTONES; HUMANS; IMMUNE TOLERANCE; IMMUNOPRECIPITATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICRORNAS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SEPSIS; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS);

EID: 80052364758     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0211074     Document Type: Article

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