Coexistence of Hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses

Journal of Virology

Volumn 88, Issue 15, 2014, Pages 8656-8666

  Cao, Liang ^a,b   Wu, Chunchen ^a   Shi, Hui ^a   Gong, Zuojiong ^c   Zhang, Ejuan ^a   Wang, Hui ^a,b   Zhao, Kaitao ^a,b   Liu, Shuhui ^a,b   Li, Songxia ^a   Gao, Xiuzhu ^d   Wang, Yun ^a   Pei, Rongjuan ^a   Lu, Mengji ^a,e,f   Chen, Xinwen ^a  

^a WUHAN INSTITUTE OF VIROLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^d THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^e UNIVERSITY HOSPITAL ESSEN   (Germany)

^f HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; VIRUS DNA; VIRUS ENVELOPE PROTEIN;

ADULT; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS B VIRUS VARIANT SH; HEPATITIS B VIRUS VARIANT SH DPS; HUMAN; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN SECRETION; SEQUENCE ANALYSIS; SPECIES COEXISTENCE; START CODON; STOP CODON; VIRUS REPLICATION;

ADULT; ANIMALS; DISEASE MODELS, ANIMAL; DNA, VIRAL; GENETIC VARIATION; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B VIRUS; HUMANS; IMMUNITY, CELLULAR; MALE; MICE; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; VIRUS REPLICATION;

EID: 84903896693     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01123-14     Document Type: Article

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