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Volumn 15, Issue 7, 2014, Pages 938-950

Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: Evidence that miR200a-3p is regulated by O6-methylguanine methyltransferase and promotes temozolomide responsiveness

Author keywords

Chemoresistance; Glioblastoma; MicroRNA; MiR 200a 3p; MiR21; Temozolomide

Indexed keywords

CARMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MICRORNA 200A; MICRORNA 21; TEMOZOLOMIDE; VINCRISTINE; ALKYLATING AGENT; DACARBAZINE; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; MICRORNA; MIRN200 MICRORNA, HUMAN; MIRN21 MICRORNA, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN;

EID: 84903848549     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.28920     Document Type: Article
Times cited : (40)

References (68)
  • 1
    • 67649120009 scopus 로고    scopus 로고
    • Biology of angiogenesis and invasion in glioma
    • PMID:19560735
    • Tate MC, Aghi MK. Biology of angiogenesis and invasion in glioma. Neurotherapeutics 2009; 6:447-57; PMID:19560735; http://dx.doi.org/10.1016/j. nurt.2009.04.001
    • (2009) Neurotherapeutics , vol.6 , pp. 447-457
    • Tate, M.C.1    Aghi, M.K.2
  • 2
    • 78650271417 scopus 로고    scopus 로고
    • Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004
    • Société Française de Neurochirurgie (SFNC); Club de Neuro-Oncologie of the Société Française de Neurochirurgie (CNOSFNC); Société Française de Neuropathologie (SFNP); Association des Neuro-Oncologues d'Expression Française (ANOCEF) PMID:20364023
    • Bauchet L, Mathieu-Daudé H, Fabbro-Peray P, Rigau V, Fabbro M, Chinot O, Pallusseau L, Carnin C, Lainé K, Schlama A, et al.; Société Française de Neurochirurgie (SFNC); Club de Neuro-Oncologie of the Société Française de Neurochirurgie (CNOSFNC); Société Française de Neuropathologie (SFNP); Association des Neuro-Oncologues d'Expression Française (ANOCEF). Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004. Neuro Oncol 2010; 12:725-35; PMID:20364023; http://dx.doi.org/10.1093/neuonc/noq030
    • (2010) Neuro Oncol , vol.12 , pp. 725-735
    • Bauchet, L.1    Mathieu-Daudé, H.2    Fabbro-Peray, P.3    Rigau, V.4    Fabbro, M.5    Chinot, O.6    Pallusseau, L.7    Carnin, C.8    Lainé, K.9    Schlama, A.10
  • 3
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group PMID:19269895
    • Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, et al.; European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009; 10:459-66; PMID:19269895; http://dx.doi.org/10.1016/S1470-2045(09)70025-7
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    Van Den Bent, M.J.4    Taphoorn, M.J.5    Janzer, R.C.6    Ludwin, S.K.7    Allgeier, A.8    Fisher, B.9    Belanger, K.10
  • 6
    • 77956809165 scopus 로고    scopus 로고
    • Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression
    • PMID:20824049
    • Le Calvé B, Rynkowski M, Le Mercier M, Bruyère C, Lonez C, Gras T, Haibe-Kains B, Bontempi G, Decaestecker C, Ruysschaert JM, et al. Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression. Neoplasia 2010; 12:727-39; PMID:20824049
    • (2010) Neoplasia , vol.12 , pp. 727-739
    • Le Calvé, B.1    Rynkowski, M.2    Le Mercier, M.3    Bruyère, C.4    Lonez, C.5    Gras, T.6    Haibe-Kains, B.7    Bontempi, G.8    Decaestecker, C.9    Ruysschaert, J.M.10
  • 8
    • 75749109750 scopus 로고    scopus 로고
    • O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients
    • PMID:20150365
    • Spiegl-Kreinecker S, Pirker C, Filipits M, Lötsch D, Buchroithner J, Pichler J, Silye R, Weis S, Micksche M, Fischer J, et al. O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients. Neuro Oncol 2010; 12:28-36; PMID:20150365; http://dx.doi.org/10.1093/neuonc/nop003
    • (2010) Neuro Oncol , vol.12 , pp. 28-36
    • Spiegl-Kreinecker, S.1    Pirker, C.2    Filipits, M.3    Lötsch, D.4    Buchroithner, J.5    Pichler, J.6    Silye, R.7    Weis, S.8    Micksche, M.9    Fischer, J.10
  • 10
    • 78549288561 scopus 로고    scopus 로고
    • MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature
    • PMID:20935218
    • Gaspar N, Marshall L, Perryman L, Bax DA, Little SE, Viana-Pereira M, Sharp SY, Vassal G, Pearson AD, Reis RM, et al. MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature. Cancer Res 2010; 70:9243-52; PMID:20935218; http://dx.doi.org/10.1158/0008-5472.CAN-10-1250
    • (2010) Cancer Res , vol.70 , pp. 9243-9252
    • Gaspar, N.1    Marshall, L.2    Perryman, L.3    Bax, D.A.4    Little, S.E.5    Viana-Pereira, M.6    Sharp, S.Y.7    Vassal, G.8    Pearson, A.D.9    Reis, R.M.10
  • 11
    • 77952207481 scopus 로고    scopus 로고
    • Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression
    • PMID:20457618
    • Bobola MS, Kolstoe DD, Blank A, Silber Jr. Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression. Mol Cancer Ther 2010; 9:1208-18; PMID:20457618; http://dx.doi.org/10.1158/1535-7163.MCT-10-0010
    • (2010) Mol Cancer Ther , vol.9 , pp. 1208-1218
    • Bobola, M.S.1    Kolstoe, D.D.2    Blank, A.3    Silber, J.R.4
  • 12
    • 77950059191 scopus 로고    scopus 로고
    • Acquired resistance to temozolomide in glioma cell lines: Molecular mechanisms and potential translational applications
    • PMID:20357518
    • Zhang J, Stevens MF, Laughton CA, Madhusudan S, Bradshaw TD. Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications. Oncology 2010; 78:103-14; PMID:20357518; http://dx.doi.org/10.1159/000306139
    • (2010) Oncology , vol.78 , pp. 103-114
    • Zhang, J.1    Stevens, M.F.2    Laughton, C.A.3    Madhusudan, S.4    Bradshaw, T.D.5
  • 13
    • 34249304804 scopus 로고    scopus 로고
    • Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir
    • DOI 10.1158/0008-5472.CAN-06-3398
    • Jiang Z, Pore N, Cerniglia GJ, Mick R, Georgescu MM, Bernhard EJ, Hahn SM, Gupta AK, Maity A. Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir. Cancer Res 2007; 67:4467-73; PMID:17483362; http://dx.doi.org/10.1158/0008-5472.CAN-06-3398 (Pubitemid 46815097)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4467-4473
    • Jiang, Z.1    Pore, N.2    Cerniglia, G.J.3    Mick, R.4    Georgescu, M.-M.5    Bernhard, E.J.6    Hahn, S.M.7    Gupta, A.K.8    Maity, A.9
  • 14
    • 84874630091 scopus 로고    scopus 로고
    • Inhibition of PI3K/AKT/mTOR pathway enhances temozolomideinduced cytotoxicity in pituitary adenoma cell lines in vitro and xenografted pituitary adenoma in female nude mice
    • PMID:23384836
    • Dai C, Zhang B, Liu X, Ma S, Yang Y, Yao Y, Feng M, Bao X, Li G, Wang J, et al. Inhibition of PI3K/AKT/mTOR pathway enhances temozolomideinduced cytotoxicity in pituitary adenoma cell lines in vitro and xenografted pituitary adenoma in female nude mice. Endocrinology 2013; 154:1247-59; PMID:23384836; http://dx.doi.org/10.1210/en.2012-1908
    • (2013) Endocrinology , vol.154 , pp. 1247-1259
    • Dai, C.1    Zhang, B.2    Liu, X.3    Ma, S.4    Yang, Y.5    Yao, Y.6    Feng, M.7    Bao, X.8    Li, G.9    Wang, J.10
  • 16
    • 84863327274 scopus 로고    scopus 로고
    • Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells
    • PMID:22564186
    • Happold C, Roth P, Wick W, Schmidt N, Florea AM, Silginer M, Reifenberger G, Weller M. Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. J Neurochem 2012; 122:444-55; PMID:22564186; http://dx.doi.org/10.1111/j.1471-4159.2012.07781.x
    • (2012) J Neurochem , vol.122 , pp. 444-455
    • Happold, C.1    Roth, P.2    Wick, W.3    Schmidt, N.4    Florea, A.M.5    Silginer, M.6    Reifenberger, G.7    Weller, M.8
  • 17
    • 79952183964 scopus 로고    scopus 로고
    • Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma
    • PMID:20593219
    • Blough MD, Beauchamp DC, Westgate MR, Kelly JJ, Cairncross JG. Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma. J Neurooncol 2011; 102:1-7; PMID:20593219; http://dx.doi.org/10.1007/s11060-010-0283-9
    • (2011) J Neurooncol , vol.102 , pp. 1-7
    • Blough, M.D.1    Beauchamp, D.C.2    Westgate, M.R.3    Kelly, J.J.4    Cairncross, J.G.5
  • 18
    • 79955782730 scopus 로고    scopus 로고
    • Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation
    • PMID:21340685
    • Chen CH, Chang YJ, Ku MSB, Chung KT, Yang JT. Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation. J Mol Med (Berl) 2011; 89:303-15; PMID:21340685; http://dx.doi.org/10.1007/s00109-010-0707-1
    • (2011) J Mol Med (Berl) , vol.89 , pp. 303-315
    • Chen, C.H.1    Chang, Y.J.2    Ku, M.S.B.3    Chung, K.T.4    Yang, J.T.5
  • 19
    • 23844457178 scopus 로고    scopus 로고
    • Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo
    • DOI 10.1158/0008-5472.CAN-05-1042
    • Momota H, Nerio E, Holland EC. Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo. Cancer Res 2005; 65:7429-35; PMID:16103096; http://dx.doi.org/10.1158/0008-5472.CAN-05-1042 (Pubitemid 41161277)
    • (2005) Cancer Research , vol.65 , Issue.16 , pp. 7429-7435
    • Momota, H.1    Nerio, E.2    Holland, E.C.3
  • 20
    • 84873342453 scopus 로고    scopus 로고
    • Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme
    • PMID:22990979
    • Zhang W, Zhang J, Yan W, You G, Bao Z, Li S, Kang C, Jiang C, You Y, Zhang Y, et al. Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme. Cancer 2013; 119:814-24; PMID:22990979; http://dx.doi.org/10.1002/cncr.27826
    • (2013) Cancer , vol.119 , pp. 814-824
    • Zhang, W.1    Zhang, J.2    Yan, W.3    You, G.4    Bao, Z.5    Li, S.6    Kang, C.7    Jiang, C.8    You, Y.9    Zhang, Y.10
  • 23
    • 77956476392 scopus 로고    scopus 로고
    • MicroRNAs: Synthesis, mechanism, function, and recent clinical trials
    • PMID:20619301
    • Wahid F, Shehzad A, Khan T, Kim YY. MicroRNAs: synthesis, mechanism, function, and recent clinical trials. Biochim Biophys Acta 2010; 1803:1231-43; PMID:20619301; http://dx.doi.org/10.1016/j.bbamcr.2010.06.013
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 1231-1243
    • Wahid, F.1    Shehzad, A.2    Khan, T.3    Kim, Y.Y.4
  • 24
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • DOI 10.1016/j.ydbio.2006.08.028, PII S0012160606010967
    • Zhang B, Pan X, Cobb GP, Anderson TA. microRNAs as oncogenes and tumor suppressors. Dev Biol 2007; 302:1-12; PMID:16989803; http://dx.doi.org/10.1016/ j.ydbio.2006.08.028 (Pubitemid 46096921)
    • (2007) Developmental Biology , vol.302 , Issue.1 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 25
    • 72949111146 scopus 로고    scopus 로고
    • MicroRNA regulation of cancer stem cells and therapeutic implications
    • PMID:19842044
    • DeSano JT, Xu L. MicroRNA regulation of cancer stem cells and therapeutic implications. AAPS J 2009; 11:682-92; PMID:19842044; http://dx.doi.org/10.1208/ s12248-009-9147-7
    • (2009) AAPS J , vol.11 , pp. 682-692
    • Desano, J.T.1    Xu, L.2
  • 26
    • 34250353602 scopus 로고    scopus 로고
    • MicroRNAs and cancer: Role in tumorigenesis, patient classification and therapy
    • PMID:17403626
    • Hernando E. microRNAs and cancer: role in tumorigenesis, patient classification and therapy. Clin Transl Oncol 2007; 9:155-60; PMID:17403626; http://dx.doi.org/10.1007/s12094-007-0029-0
    • (2007) Clin Transl Oncol , vol.9 , pp. 155-160
    • Hernando, E.1
  • 27
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumorsuppressive pathways in glioblastoma cells
    • PMID:18829576
    • Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumorsuppressive pathways in glioblastoma cells. Cancer Res 2008; 68:8164-72; PMID:18829576; http://dx.doi.org/10.1158/0008-5472.CAN-08-1305
    • (2008) Cancer Res , vol.68 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 29
    • 84871787992 scopus 로고    scopus 로고
    • MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas
    • PMID:23104517
    • Hermansen SK, Dahlrot RH, Nielsen BS, Hansen S, Kristensen BW. MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas. J Neurooncol 2013; 111:71-81; PMID:23104517; http://dx.doi.org/10.1007/ s11060-012-0992-3
    • (2013) J Neurooncol , vol.111 , pp. 71-81
    • Hermansen, S.K.1    Dahlrot, R.H.2    Nielsen, B.S.3    Hansen, S.4    Kristensen, B.W.5
  • 30
    • 81855192731 scopus 로고    scopus 로고
    • MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients
    • PMID:21895872
    • Lakomy R, Sana J, Hankeova S, Fadrus P, Kren L, Lzicarova E, Svoboda M, Dolezelova H, Smrcka M, Vyzula R, et al. MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients. Cancer Sci 2011; 102:2186-90; PMID:21895872; http://dx.doi.org/10.1111/j.1349-7006.2011.02092.x
    • (2011) Cancer Sci , vol.102 , pp. 2186-2190
    • Lakomy, R.1    Sana, J.2    Hankeova, S.3    Fadrus, P.4    Kren, L.5    Lzicarova, E.6    Svoboda, M.7    Dolezelova, H.8    Smrcka, M.9    Vyzula, R.10
  • 31
    • 77956556260 scopus 로고    scopus 로고
    • MicroRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival
    • PMID:20393129
    • Rossi S, Shimizu M, Barbarotto E, Nicoloso MS, Dimitri F, Sampath D, Fabbri M, Lerner S, Barron LL, Rassenti LZ, et al. microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. Blood 2010; 116:945-52; PMID:20393129; http://dx.doi.org/10.1182/blood-2010-01-263889
    • (2010) Blood , vol.116 , pp. 945-952
    • Rossi, S.1    Shimizu, M.2    Barbarotto, E.3    Nicoloso, M.S.4    Dimitri, F.5    Sampath, D.6    Fabbri, M.7    Lerner, S.8    Barron, L.L.9    Rassenti, L.Z.10
  • 32
    • 77954315239 scopus 로고    scopus 로고
    • Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
    • PMID:20363096
    • Gao W, Yu Y, Cao H, Shen H, Li X, Pan S, Shu Y. Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed Pharmacother 2010; 64:399-408; PMID:20363096; http://dx.doi.org/10.1016/j.biopha.2010.01.018
    • (2010) Biomed Pharmacother , vol.64 , pp. 399-408
    • Gao, W.1    Yu, Y.2    Cao, H.3    Shen, H.4    Li, X.5    Pan, S.6    Shu, Y.7
  • 33
    • 77956296766 scopus 로고    scopus 로고
    • Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer
    • PMID:20498843
    • Hwang JH, Voortman J, Giovannetti E, Steinberg SM, Leon LG, Kim YT, Funel N, Park JK, Kim MA, Kang GH, et al. Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer. PLoS One 2010; 5:e10630; PMID:20498843; http://dx.doi.org/10.1371/journal.pone.0010630
    • (2010) PLoS One , vol.5
    • Hwang, J.H.1    Voortman, J.2    Giovannetti, E.3    Steinberg, S.M.4    Leon, L.G.5    Kim, Y.T.6    Funel, N.7    Park, J.K.8    Kim, M.A.9    Kang, G.H.10
  • 34
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • DOI 10.1038/embor.2008.74, PII EMBOR200874
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9:582-9; PMID:18483486; http://dx.doi.org/10.1038/embor.2008.74 (Pubitemid 351772923)
    • (2008) EMBO Reports , vol.9 , Issue.6 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 35
  • 37
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • PMID:19665978
    • Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, Diehn M, Liu H, Panula SP, Chiao E, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138:592-603; PMID:19665978; http://dx.doi.org/10.1016/j.cell.2009.07.011
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3    Lobo, N.4    Dalerba, P.5    Qian, D.6    Diehn, M.7    Liu, H.8    Panula, S.P.9    Chiao, E.10
  • 39
    • 69249096109 scopus 로고    scopus 로고
    • Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabineresistant pancreatic cancer cells
    • PMID:19654291
    • Li Y, VandenBoom TG, Kong D, Wang Z, Ali S, Philip PA, Sarkar FH. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabineresistant pancreatic cancer cells. Cancer Res 2009; 69:6704-12; PMID:19654291; http://dx.doi.org/10.1158/ 0008-5472.CAN-09-1298
    • (2009) Cancer Res , vol.69 , pp. 6704-6712
    • Li, Y.1    Vandenboom, T.G.2    Kong, D.3    Wang, Z.4    Ali, S.5    Philip, P.A.6    Sarkar, F.H.7
  • 40
    • 69349087756 scopus 로고    scopus 로고
    • MiR-200 expression regulates epithelialto-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy
    • PMID:19671845
    • Adam L, Zhong M, Choi W, Qi W, Nicoloso M, Arora A, Calin G, Wang H, Siefker-Radtke A, McConkey D, et al. miR-200 expression regulates epithelialto-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res 2009; 15:5060-72; PMID:19671845; http://dx.doi.org/10.1158/1078-0432.CCR-08-2245
    • (2009) Clin Cancer Res , vol.15 , pp. 5060-5072
    • Adam, L.1    Zhong, M.2    Choi, W.3    Qi, W.4    Nicoloso, M.5    Arora, A.6    Calin, G.7    Wang, H.8    Siefker-Radtke, A.9    McConkey, D.10
  • 41
    • 67449119421 scopus 로고    scopus 로고
    • MiRNA expression profiling in melanocytes and melanoma cell lines reveals miRNAs associated with formation and progression of malignant melanoma
    • PMID:19212343
    • Mueller DW, Rehli M, Bosserhoff AK. miRNA expression profiling in melanocytes and melanoma cell lines reveals miRNAs associated with formation and progression of malignant melanoma. J Invest Dermatol 2009; 129:1740-51; PMID:19212343; http://dx.doi.org/10.1038/jid.2008.452
    • (2009) J Invest Dermatol , vol.129 , pp. 1740-1751
    • Mueller, D.W.1    Rehli, M.2    Bosserhoff, A.K.3
  • 42
    • 43049133807 scopus 로고    scopus 로고
    • MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth
    • DOI 10.1038/cr.2008.45, PII CR200845
    • Schultz J, Lorenz P, Gross G, Ibrahim S, Kunz M. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res 2008; 18:549-57; PMID:18379589; http://dx.doi.org/10.1038/cr.2008.45 (Pubitemid 351630945)
    • (2008) Cell Research , vol.18 , Issue.5 , pp. 549-557
    • Schultz, J.1    Lorenz, P.2    Gross, G.3    Ibrahim, S.4    Kunz, M.5
  • 45
    • 70350532244 scopus 로고    scopus 로고
    • Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway
    • PMID:19703993
    • Saydam O, Shen Y, Würdinger T, Senol O, Boke E, James MF, Tannous BA, Stemmer-Rachamimov AO, Yi M, Stephens RM, et al. Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway. Mol Cell Biol 2009; 29:5923-40; PMID:19703993; http://dx.doi.org/10.1128/MCB.00332-09
    • (2009) Mol Cell Biol , vol.29 , pp. 5923-5940
    • Saydam, O.1    Shen, Y.2    Würdinger, T.3    Senol, O.4    Boke, E.5    James, M.F.6    Tannous, B.A.7    Stemmer-Rachamimov, A.O.8    Yi, M.9    Stephens, R.M.10
  • 46
    • 84886588314 scopus 로고    scopus 로고
    • The Cdk inhibitor flavopiridol enhances temozolomideinduced cytotoxicity in human glioma cells
    • PMID:23943501
    • Hayashi T, Adachi K, Ohba S, Hirose Y. The Cdk inhibitor flavopiridol enhances temozolomideinduced cytotoxicity in human glioma cells. J Neurooncol 2013; 115:169-78; PMID:23943501; http://dx.doi.org/10.1007/s11060-013-1220-5
    • (2013) J Neurooncol , vol.115 , pp. 169-178
    • Hayashi, T.1    Adachi, K.2    Ohba, S.3    Hirose, Y.4
  • 47
    • 84892450078 scopus 로고    scopus 로고
    • Mechanism of temozolomide-induced antitumour effects on glioma cells
    • PMID:24326954
    • Shen W, Hu J-A, Zheng J-S. Mechanism of temozolomide-induced antitumour effects on glioma cells. J Int Med Res 2014; 42:164-72; PMID:24326954; http://dx.doi.org/10.1177/0300060513501753
    • (2014) J Int Med Res , vol.42 , pp. 164-172
    • Shen, W.1    Hu, J.-A.2    Zheng, J.-S.3
  • 48
    • 84875145824 scopus 로고    scopus 로고
    • Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomideinduced senescence in glioma cells
    • PMID:23522185
    • Filippi-Chiela EC, Thomé MP, Bueno e Silva MM, Pelegrini AL, Ledur PF, Garicochea B, Zamin LL, Lenz G. Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomideinduced senescence in glioma cells. BMC Cancer 2013; 13:147-56; PMID:23522185; http://dx.doi.org/10.1186/1471-2407-13-147
    • (2013) BMC Cancer , vol.13 , pp. 147-156
    • Filippi-Chiela, E.C.1    Thomé, M.P.2    Bueno Silva, E.M.M.3    Pelegrini, A.L.4    Ledur, P.F.5    Garicochea, B.6    Zamin, L.L.7    Lenz, G.8
  • 49
    • 0035884608 scopus 로고    scopus 로고
    • Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis
    • Rickman DS, Bobek MP, Misek DE, Kuick R, Blaivas M, Kurnit DM, Taylor J, Hanash SM. Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. Cancer Res 2001; 61:6885-91; PMID:11559565 (Pubitemid 32896514)
    • (2001) Cancer Research , vol.61 , Issue.18 , pp. 6885-6891
    • Rickman, D.S.1    Bobek, M.P.2    Misek, D.E.3    Kuick, R.4    Blaivas, M.5    Kurnit, D.M.6    Taylor, J.7    Hanash, S.M.8
  • 50
    • 0042425741 scopus 로고    scopus 로고
    • Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
    • van den Boom J, Wolter M, Kuick R, Misek DE, Youkilis AS, Wechsler DS, Sommer C, Reifenberger G, Hanash SM. Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and realtime reverse transcription-polymerase chain reaction. Am J Pathol 2003; 163:1033-43; PMID:12937144; http://dx.doi.org/10. 1016/S0002-9440(10)63463-3 (Pubitemid 37040139)
    • (2003) American Journal of Pathology , vol.163 , Issue.3 , pp. 1033-1043
    • Van Den Boom, J.1    Wolter, M.2    Kuick, R.3    Misek, D.E.4    Youkilis, A.S.5    Wechsler, D.S.6    Sommer, C.7    Reifenberger, G.8    Hanash, S.M.9
  • 51
  • 52
    • 84859480864 scopus 로고    scopus 로고
    • Clinical outcome prediction by microRNAs in human cancer: A systematic review
    • PMID:22395642
    • Nair VS, Maeda LS, Ioannidis JP. Clinical outcome prediction by microRNAs in human cancer: a systematic review. J Natl Cancer Inst 2012; 104:528-40; PMID:22395642; http://dx.doi.org/10.1093/jnci/djs027
    • (2012) J Natl Cancer Inst , vol.104 , pp. 528-540
    • Nair, V.S.1    Maeda, L.S.2    Ioannidis, J.P.3
  • 53
    • 84872050193 scopus 로고    scopus 로고
    • Interactions of miR-323/miR-329 and miR-130a/miR155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
    • PMID:23281771
    • Qiu S, Lin S, Hu D, Feng Y, Tan Y, Peng Y. Interactions of miR-323/miR-329 and miR-130a/miR155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients. J Transl Med 2013; 11:10; PMID:23281771; http://dx.doi.org/10.1186/1479-5876-11-10
    • (2013) J Transl Med , vol.11 , pp. 10
    • Qiu, S.1    Lin, S.2    Hu, D.3    Feng, Y.4    Tan, Y.5    Peng, Y.6
  • 54
    • 84878343722 scopus 로고    scopus 로고
    • NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200
    • PMID:23482671
    • Fu J, Rodova M, Nanta R, Meeker D, Van Veldhuizen PJ, Srivastava RK, Shankar S. NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200. Neuro Oncol 2013; 15:691-706; PMID:23482671; http://dx.doi.org/10. 1093/neuonc/not011
    • (2013) Neuro Oncol , vol.15 , pp. 691-706
    • Fu, J.1    Rodova, M.2    Nanta, R.3    Meeker, D.4    Van Veldhuizen, P.J.5    Srivastava, R.K.6    Shankar, S.7
  • 55
    • 70350109380 scopus 로고    scopus 로고
    • Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation
    • PMID:19637364
    • Metellus P, Coulibaly B, Nanni I, Fina F, Eudes N, Giorgi R, Barrie M, Chinot O, Fuentes S, Dufour H, et al. Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation. Cancer 2009; 115:4783-94; PMID:19637364; http://dx.doi.org/10.1002/cncr.24546
    • (2009) Cancer , vol.115 , pp. 4783-4794
    • Metellus, P.1    Coulibaly, B.2    Nanni, I.3    Fina, F.4    Eudes, N.5    Giorgi, R.6    Barrie, M.7    Chinot, O.8    Fuentes, S.9    Dufour, H.10
  • 56
    • 84865471981 scopus 로고    scopus 로고
    • MiRNAs as mediators of drug resistance
    • PMID:22920178
    • Haenisch S, Cascorbi I. miRNAs as mediators of drug resistance. Epigenomics 2012; 4:369-81; PMID:22920178; http://dx.doi.org/10.2217/epi.12.39
    • (2012) Epigenomics , vol.4 , pp. 369-381
    • Haenisch, S.1    Cascorbi, I.2
  • 57
    • 77349125856 scopus 로고    scopus 로고
    • MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTENmutant) and LN229 (PTEN-wild type) to taxol
    • PMID:20113523
    • Ren Y, Zhou X, Mei M, Yuan XB, Han L, Wang GX, Jia ZF, Xu P, Pu PY, Kang CS. MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTENmutant) and LN229 (PTEN-wild type) to taxol. BMC Cancer 2010; 10:27-34; PMID:20113523; http://dx.doi.org/10.1186/1471-2407-10-27
    • (2010) BMC Cancer , vol.10 , pp. 27-34
    • Ren, Y.1    Zhou, X.2    Mei, M.3    Yuan, X.B.4    Han, L.5    Wang, G.X.6    Jia, Z.F.7    Xu, P.8    Pu, P.Y.9    Kang, C.S.10
  • 58
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell-delivered S-TRAIL in human gliomas
    • DOI 10.1158/0008-5472.CAN-07-1045
    • Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res 2007; 67:8994-9000; PMID:17908999; http://dx.doi.org/10.1158/0008- 5472.CAN-07-1045 (Pubitemid 47535880)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 59
    • 77956178738 scopus 로고    scopus 로고
    • MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity
    • PMID:20633539
    • Shi L, Chen J, Yang J, Pan T, Zhang S, Wang Z. MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res 2010; 1352:255-64; PMID:20633539; http://dx.doi.org/10.1016/j.brainres.2010.07.009
    • (2010) Brain Res , vol.1352 , pp. 255-264
    • Shi, L.1    Chen, J.2    Yang, J.3    Pan, T.4    Zhang, S.5    Wang, Z.6
  • 60
    • 80955180085 scopus 로고    scopus 로고
    • A miR-21 inhibitor enhances apoptosis and reduces G(2)-M accumulation induced by ionizing radiation in human glioblastoma U251 cells
    • PMID:21618027
    • Li Y, Zhao S, Zhen Y, Li Q, Teng L, Asai A, Kawamoto K. A miR-21 inhibitor enhances apoptosis and reduces G(2)-M accumulation induced by ionizing radiation in human glioblastoma U251 cells. Brain Tumor Pathol 2011; 28:209-14; PMID:21618027; http://dx.doi.org/10.1007/s10014-011-0037-1
    • (2011) Brain Tumor Pathol , vol.28 , pp. 209-214
    • Li, Y.1    Zhao, S.2    Zhen, Y.3    Li, Q.4    Teng, L.5    Asai, A.6    Kawamoto, K.7
  • 61
    • 84865681797 scopus 로고    scopus 로고
    • MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells
    • PMID:22753745
    • Wong ST, Zhang XQ, Zhuang JT, Chan HL, Li CH, Leung GK. MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells. Anticancer Res 2012; 32:2835-41; PMID:22753745
    • (2012) Anticancer Res , vol.32 , pp. 2835-2841
    • Wong, S.T.1    Zhang, X.Q.2    Zhuang, J.T.3    Chan, H.L.4    Li, C.H.5    Leung, G.K.6
  • 62
    • 77951745289 scopus 로고    scopus 로고
    • Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF
    • PMID:20388782
    • Ali S, Ahmad A, Banerjee S, Padhye S, Dominiak K, Schaffert JM, Wang Z, Philip PA, Sarkar FH. Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF. Cancer Res 2010; 70:3606-17; PMID:20388782; http://dx.doi.org/10.1158/0008-5472.CAN-09-4598
    • (2010) Cancer Res , vol.70 , pp. 3606-3617
    • Ali, S.1    Ahmad, A.2    Banerjee, S.3    Padhye, S.4    Dominiak, K.5    Schaffert, J.M.6    Wang, Z.7    Philip, P.A.8    Sarkar, F.H.9
  • 63
    • 84874405804 scopus 로고    scopus 로고
    • O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation
    • PMID:22892544
    • Noonan EM, Shah D, Yaffe MB, Lauffenburger DA, Samson LD. O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation. Integr Biol (Camb) 2012; 4:1237-55; PMID:22892544; http://dx.doi.org/10.1039/c2ib20091k
    • (2012) Integr Biol (Camb) , vol.4 , pp. 1237-1255
    • Noonan, E.M.1    Shah, D.2    Yaffe, M.B.3    Lauffenburger, D.A.4    Samson, L.D.5
  • 64
    • 84876093576 scopus 로고    scopus 로고
    • DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis
    • PMID:22261329
    • Roos WP, Kaina B. DNA damage-induced cell death: from specific DNA lesions to the DNA damage response and apoptosis. Cancer Lett 2013; 332:237-48; PMID:22261329; http://dx.doi.org/10.1016/j.canlet.2012.01.007
    • (2013) Cancer Lett , vol.332 , pp. 237-248
    • Roos, W.P.1    Kaina, B.2
  • 66
    • 59949101538 scopus 로고    scopus 로고
    • Adrenomedullin promotes cell cycle transit and up-regulates cyclin D1 protein level in human glioblastoma cells through the activation of c-Jun/JNK/AP-1 signal transduction pathway
    • PMID:19166930
    • Ouafik L, Berenguer-Daize C, Berthois Y. Adrenomedullin promotes cell cycle transit and up-regulates cyclin D1 protein level in human glioblastoma cells through the activation of c-Jun/JNK/AP-1 signal transduction pathway. Cell Signal 2009; 21:597-608; PMID:19166930; http://dx.doi.org/10.1016/j.cellsig. 2009.01.001
    • (2009) Cell Signal , vol.21 , pp. 597-608
    • Ouafik, L.1    Berenguer-Daize, C.2    Berthois, Y.3
  • 68
    • 2542629617 scopus 로고    scopus 로고
    • Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen
    • DOI 10.1158/0008-5472.CAN-03-3852
    • Widschwendter M, Siegmund KD, Müller HM, Fiegl H, Marth C, Müller-Holzner E, Jones PA, Laird PW. Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Res 2004; 64:3807-13; PMID:15172987; http://dx.doi.org/10.1158/0008-5472. CAN-03-3852 (Pubitemid 38697289)
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3807-3813
    • Widschwendter, M.1    Siegmund, K.D.2    Muller, H.M.3    Fiegl, H.4    Marth, C.5    Muller-Holzner, E.6    Jones, P.A.7    Laird, P.W.8


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