-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E and Mirimanoff RO: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996, 2005. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den, B.M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
2
-
-
66349087039
-
Temozolomide with radiation therapy in high-grade brain gliomas: Pharmaceuticals considerations and efficacy; a review article
-
Koukourakis GV, Kouloulias V, Zacharias G, Papadimitriou C, Pantelakos P, Maravelis G, Fotineas A, Beli I, Chaldeopoulos D and Kouvaris J: Temozolomide with radiation therapy in high-grade brain gliomas: pharmaceuticals considerations and efficacy; a review article. Molecules 14: 1561-1577, 2009.
-
(2009)
Molecules
, vol.14
, pp. 1561-1577
-
-
Koukourakis, G.V.1
Kouloulias, V.2
Zacharias, G.3
Papadimitriou, C.4
Pantelakos, P.5
Maravelis, G.6
Fotineas, A.7
Beli, I.8
Chaldeopoulos, D.9
Kouvaris, J.10
-
3
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, Hau P, Brandes AA, Gijtenbeek J, Marosi C, Vecht CJ, Mokhtari K, Wesseling P, Villa S, Eisenhauer E, Gorlia T, Weller M, Lacombe D, Cairncross JG and Mirimanoff RO: Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10 : 459-466, 2009.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
Van Den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
Ludwin, S.K.7
Allgeier, A.8
Fisher, B.9
Belanger, K.10
Hau, P.11
Brandes, A.A.12
Gijtenbeek, J.13
Marosi, C.14
Vecht, C.J.15
Mokhtari, K.16
Wesseling, P.17
Villa, S.18
Eisenhauer, E.19
Gorlia, T.20
Weller, M.21
Lacombe, D.22
Cairncross, J.G.23
Mirimanoff, R.O.24
more..
-
4
-
-
0036023439
-
Multifaceted resistance of gliomas to temozolomide
-
Bocangel DB, Finkelstein S, Schold SC, Bhakat KK, Mitra S and Kokkinakis DM: Multifaceted resistance of gliomas to temozolomide. Clin Cancer Res 8: 2725-2734, 2002. (Pubitemid 34856362)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.8
, pp. 2725-2734
-
-
Bocangel, D.B.1
Finkelstein, S.2
Clifford, S.S.3
Bhakat, K.K.4
Mitra, S.5
Kokkinakis, D.M.6
-
5
-
-
62349087854
-
Recent approaches to improve the antitumor efficacy of temozolomide
-
Tentori L and Graziani G: Recent approaches to improve the antitumor efficacy of temozolomide. Curr Med Chem 16: 245-257, 2009.
-
(2009)
Curr Med Chem
, vol.16
, pp. 245-257
-
-
Tentori, L.1
Graziani, G.2
-
6
-
-
77958024321
-
Targeting miR-21 in glioma: A small RNA with big potential
-
Moore LM and Zhang W: Targeting miR-21 in glioma: a small RNA with big potential. Expert Opin Ther Targets 14: 1247-1257, 2010.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 1247-1257
-
-
Moore, L.M.1
Zhang, W.2
-
7
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
9
-
-
77950824571
-
Identification and functional characterization of microRNAs involved in the malignant progression of gliomas
-
Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stuhler K, Meyer HE and Reifenberger G: Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol 20: 539-550, 2010.
-
(2010)
Brain Pathol
, vol.20
, pp. 539-550
-
-
Malzkorn, B.1
Wolter, M.2
Liesenberg, F.3
Grzendowski, M.4
Stuhler, K.5
Meyer, H.E.6
Reifenberger, G.7
-
10
-
-
23044464236
-
Extensive modulation of a set of microRNAs in primary glioblastoma
-
DOI 10.1016/j.bbrc.2005.07.030, PII S0006291X05014816
-
Ciafre SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G, Negrini M, Maira G, Croce CM and Farace MG: Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 334: 1351-1358, 2005. (Pubitemid 41074723)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.334
, Issue.4
, pp. 1351-1358
-
-
Ciafre, S.A.1
Galardi, S.2
Mangiola, A.3
Ferracin, M.4
Liu, C.-G.5
Sabatino, G.6
Negrini, M.7
Maira, G.8
Croce, C.M.9
Farace, M.G.10
-
11
-
-
67349247040
-
miR-21 and 221 upregulation and miR-181b down-regulation in human grade II-IV astrocytic tumors
-
Conti A, Aguennouz M, La Torre D, Tomasello C, Cardali S, Angileri FF, Maio F, Cama A, Germano A, Vita G and Tomasello F: miR-21 and 221 upregulation and miR-181b down-regulation in human grade II-IV astrocytic tumors. J Neurooncol 93: 325-332, 2009.
-
(2009)
J Neurooncol
, vol.93
, pp. 325-332
-
-
Conti, A.1
Aguennouz, M.2
La Torre, D.3
Tomasello, C.4
Cardali, S.5
Angileri, F.F.6
Maio, F.7
Cama, A.8
Germano, A.9
Vita, G.10
Tomasello, F.11
-
12
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
DOI 10.1158/0008-5472.CAN-05-0137
-
Chan JA, Krichevsky AM and Kosik KS: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033, 2005. (Pubitemid 40994386)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
13
-
-
50249173450
-
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
-
Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS and Krichevsky AM: MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 28 : 5369-5380, 2008.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5369-5380
-
-
Gabriely, G.1
Wurdinger, T.2
Kesari, S.3
Esau, C.C.4
Burchard, J.5
Linsley, P.S.6
Krichevsky, A.M.7
-
14
-
-
54249136806
-
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
-
Papagiannakopoulos T, Shapiro A and Kosik KS: MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 68 : 8164-8172, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 8164-8172
-
-
Papagiannakopoulos, T.1
Shapiro, A.2
Kosik, K.S.3
-
15
-
-
77956178738
-
miR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing BAX/BCL-2 ratio and caspase-3 activity
-
Shi L, Chen J, Yang J, Pan T, Zhang S and Wang Z: miR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing BAX/BCL-2 ratio and caspase-3 activity. Brain Res 1352: 255-264, 2010.
-
(2010)
Brain Res
, vol.1352
, pp. 255-264
-
-
Shi, L.1
Chen, J.2
Yang, J.3
Pan, T.4
Zhang, S.5
Wang, Z.6
-
16
-
-
84455194000
-
MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis
-
Shi L, Zhang S, Feng K, Wu F, Wan Y, Wang Z, Zhang J, Wang Y, Yan W, Fu Z and You Y: MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis. Int J Oncol 40 : 119-129, 2012.
-
(2012)
Int J Oncol
, vol.40
, pp. 119-129
-
-
Shi, L.1
Zhang, S.2
Feng, K.3
Wu, F.4
Wan, Y.5
Wang, Z.6
Zhang, J.7
Wang, Y.8
Yan, W.9
Fu, Z.10
You, Y.11
-
17
-
-
84861697239
-
Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines
-
Sun S, Wong TS, Zhang XQ, Pu JK, Lee NP, Day PJ, Ng GK, Lui WM and Leung GK: Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines. J Neurooncol 107: 89-100, 2012.
-
(2012)
J Neurooncol
, vol.107
, pp. 89-100
-
-
Sun, S.1
Wong, T.S.2
Zhang, X.Q.3
Pu, J.K.4
Lee, N.P.5
Day, P.J.6
Ng, G.K.7
Lui, W.M.8
Leung, G.K.9
-
18
-
-
42149132635
-
Chemoresistance in gliomas
-
Lu C and Shervington A: Chemoresistance in gliomas. Mol Cell Biochem 312: 71-80, 2008.
-
(2008)
Mol Cell Biochem
, vol.312
, pp. 71-80
-
-
Lu, C.1
Shervington, A.2
-
19
-
-
40049100067
-
Overcoming therapeutic resistance in malignant gliomas: Current practices and future directions
-
Chakravarti A and Palanichamy K: Overcoming therapeutic resistance in malignant gliomas: current practices and future directions. Cancer Treat Res 139: 173-189, 2008.
-
(2008)
Cancer Treat Res
, vol.139
, pp. 173-189
-
-
Chakravarti, A.1
Palanichamy, K.2
-
20
-
-
77954218647
-
Potential therapeutic implications of cancer stem cells in glioblastoma
-
Cheng L, Bao S and Rich JN: Potential therapeutic implications of cancer stem cells in glioblastoma. Biochem Pharmacol 80: 654-665, 2010.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 654-665
-
-
Cheng, L.1
Bao, S.2
Rich, J.N.3
-
21
-
-
64849111009
-
Clinical significance of miR-21 expression in breast cancer: SYBR-Green I-based real-time RT-PCR study of invasive ductal carcinoma
-
Huang GL, Zhang XH, Guo GL, Huang KT, Yang KY, Shen X, You J and Hu XQ: Clinical significance of miR-21 expression in breast cancer: SYBR-Green I-based real-time RT-PCR study of invasive ductal carcinoma. Oncol Rep 21: 673-679, 2009.
-
(2009)
Oncol Rep
, vol.21
, pp. 673-679
-
-
Huang, G.L.1
Zhang, X.H.2
Guo, G.L.3
Huang, K.T.4
Yang, K.Y.5
Shen, X.6
You, J.7
Hu, X.Q.8
-
22
-
-
54049115558
-
Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR
-
Markou A, Tsaroucha EG, Kaklamanis L, Fotinou M, Georgoulias V and Lianidou ES: Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative real-time RT-PCR. Clin Chem 54: 1696-1704, 2008.
-
(2008)
Clin Chem
, vol.54
, pp. 1696-1704
-
-
Markou, A.1
Tsaroucha, E.G.2
Kaklamanis, L.3
Fotinou, M.4
Georgoulias, V.5
Lianidou, E.S.6
-
23
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
DOI 10.1038/sj.onc.1210856, PII 1210856
-
Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S and Allgayer H: MicroRNA-21 (miR-21) post-transcriptionally down-regulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27 : 2128-2136, 2008. (Pubitemid 351485639)
-
(2008)
Oncogene
, vol.27
, Issue.15
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.K.2
Nikolova, D.A.3
Leupold, J.H.4
Colburn, N.H.5
Post, S.6
Allgayer, H.7
-
24
-
-
34547524771
-
MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer
-
DOI 10.1053/j.gastro.2007.05.022, PII S0016508507010025
-
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST and Patel T: MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658, 2007. (Pubitemid 47187346)
-
(2007)
Gastroenterology
, vol.133
, Issue.2
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
25
-
-
34347266556
-
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
-
DOI 10.1074/jbc.M611393200
-
Zhu S, Si ML, Wu H and Mo YY: MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282: 14328-14336, 2007. (Pubitemid 47100416)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.19
, pp. 14328-14336
-
-
Zhu, S.1
Si, M.-L.2
Wu, H.3
Mo, Y.-Y.4
-
26
-
-
77952583615
-
The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma
-
Zhi F, Chen X, Wang S, Xia X, Shi Y, Guan W, Shao N, Qu H, Yang C, Zhang Y, Wang Q, Wang R, Zen K, Zhang CY, Zhang J and Yang Y: The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma. Eur J Cancer 46: 1640-1649, 2010.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1640-1649
-
-
Zhi, F.1
Chen, X.2
Wang, S.3
Xia, X.4
Shi, Y.5
Guan, W.6
Shao, N.7
Qu, H.8
Yang, C.9
Zhang, Y.10
Wang, Q.11
Wang, R.12
Zen, K.13
Zhang, C.Y.14
Zhang, J.15
Yang, Y.16
-
27
-
-
84863715591
-
Serum microRNA-21 is a novel biomarker in patients with esophageal squamous cell carcinoma
-
Feb 21. doi: 10.1002/jso.23064. [Epub ahead of print].
-
Kurashige J, Kamohara H, Watanabe M, Tanaka Y, Kinoshita K, Saito S, Hiyoshi Y, Iwatsuki M, Baba Y and Baba H: Serum microRNA-21 is a novel biomarker in patients with esophageal squamous cell carcinoma. J Surg Oncol, 2012 Feb 21. doi: 10.1002/jso.23064. [Epub ahead of print].
-
(2012)
J Surg Oncol
-
-
Kurashige, J.1
Kamohara, H.2
Watanabe, M.3
Tanaka, Y.4
Kinoshita, K.5
Saito, S.6
Hiyoshi, Y.7
Iwatsuki, M.8
Baba, Y.9
Baba, H.10
-
28
-
-
77349125856
-
MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol
-
Ren Y, Zhou X, Mei M, Yuan XB, Han L, Wang GX, Jia ZF, Xu P, Pu PY and Kang CS: MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol. BMC Cancer 10: 27, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 27
-
-
Ren, Y.1
Zhou, X.2
Mei, M.3
Yuan, X.B.4
Han, L.5
Wang, G.X.6
Jia, Z.F.7
Xu, P.8
Pu, P.Y.9
Kang, C.S.10
-
29
-
-
77952963826
-
Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3
-
Zhou X, Zhang J, Jia Q, Ren Y, Wang Y, Shi L, Liu N, Wang G, Pu P, You Y and Kang C: Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3. Oncol Rep 24: 195-201, 2010.
-
(2010)
Oncol Rep
, vol.24
, pp. 195-201
-
-
Zhou, X.1
Zhang, J.2
Jia, Q.3
Ren, Y.4
Wang, Y.5
Shi, L.6
Liu, N.7
Wang, G.8
Pu, P.9
You, Y.10
Kang, C.11
-
30
-
-
75949106927
-
Down-regulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status
-
Zhou X, Ren Y, Moore L, Mei M, You Y, Xu P, Wang B, Wang G, Jia Z, Pu P, Zhang W and Kang C: Down-regulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Invest 90: 144-155, 2010.
-
(2010)
Lab Invest
, vol.90
, pp. 144-155
-
-
Zhou, X.1
Ren, Y.2
Moore, L.3
Mei, M.4
You, Y.5
Xu, P.6
Wang, B.7
Wang, G.8
Jia, Z.9
Pu, P.10
Zhang, W.11
Kang, C.12
-
31
-
-
77954655739
-
MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients
-
Slaby O, Lakomy R, Fadrus P, Hrstka R, Kren L, Lzicarova E, Smrcka M, Svoboda M, Dolezalova H, Novakova J, Valik D, Vyzula R and Michalek J: MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients. Neoplasma 57: 264-269, 2010.
-
(2010)
Neoplasma
, vol.57
, pp. 264-269
-
-
Slaby, O.1
Lakomy, R.2
Fadrus, P.3
Hrstka, R.4
Kren, L.5
Lzicarova, E.6
Smrcka, M.7
Svoboda, M.8
Dolezalova, H.9
Novakova, J.10
Valik, D.11
Vyzula, R.12
Michalek, J.13
-
32
-
-
77955282214
-
miR-195, miR-455-3p and miR-10a(&z.ast;) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells
-
Ujifuku K, Mitsutake N, Takakura S, Matsuse M, Saenko V, Suzuki K, Hayashi K, Matsuo T, Kamada K, Nagata I and Yamashita S: miR-195, miR-455-3p and miR-10a(&z.ast;) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells. Cancer Lett 296: 241-248, 2010.
-
(2010)
Cancer Lett
, vol.296
, pp. 241-248
-
-
Ujifuku, K.1
Mitsutake, N.2
Takakura, S.3
Matsuse, M.4
Saenko, V.5
Suzuki, K.6
Hayashi, K.7
Matsuo, T.8
Kamada, K.9
Nagata, I.10
Yamashita, S.11
-
33
-
-
78449307957
-
Functional microRNA is transferred between glioma cells
-
Katakowski M, Buller B, Wang X, Rogers T and Chopp M: Functional microRNA is transferred between glioma cells. Cancer Res 70: 8259-8263, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 8259-8263
-
-
Katakowski, M.1
Buller, B.2
Wang, X.3
Rogers, T.4
Chopp, M.5
-
34
-
-
60849128839
-
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors
-
Allard E, Passirani C and Benoit JP: Convection-enhanced delivery of nanocarriers for the treatment of brain tumors. Biomaterials 30: 2302-2318, 2009.
-
(2009)
Biomaterials
, vol.30
, pp. 2302-2318
-
-
Allard, E.1
Passirani, C.2
Benoit, J.P.3
-
35
-
-
77951194366
-
Reduced seed region-based off-target activity with lentivirus-mediated RNAi
-
Klinghoffer RA, Magnus J, Schelter J, Mehaffey M, Coleman C and Cleary MA: Reduced seed region-based off-target activity with lentivirus-mediated RNAi. RNA 16: 879-884, 2010.
-
(2010)
RNA
, vol.16
, pp. 879-884
-
-
Klinghoffer, R.A.1
Magnus, J.2
Schelter, J.3
Mehaffey, M.4
Coleman, C.5
Cleary, M.A.6
-
36
-
-
79959808781
-
The elephant in the room: Do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma?
-
Purow B: The elephant in the room: Do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma? J Neurooncol 103: 429-436, 2011.
-
(2011)
J Neurooncol
, vol.103
, pp. 429-436
-
-
Purow, B.1
|