메뉴 건너뛰기




Volumn 4, Issue 4, 2012, Pages 369-381

MiRNAs as mediators of drug resistance

Author keywords

CpG islands; DNA methylation; drug transport; gene silencing; histone acetylation; miRNA

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ABC TRANSPORTER; ALPHA INTERFERON; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; DACINOSTAT; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; FULVESTRANT; IMATINIB; MICRORNA; MITOMYCIN; MITOXANTRONE; PACLITAXEL; TAMOXIFEN; TEMOZOLOMIDE; TRASTUZUMAB; VINCRISTINE; VORINOSTAT;

EID: 84865471981     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.12.39     Document Type: Review
Times cited : (64)

References (97)
  • 1
    • 79961221664 scopus 로고    scopus 로고
    • The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life
    • Szyf M. The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life. Epigenetics 6(8), 971-978 (2011).
    • (2011) Epigenetics , vol.6 , Issue.8 , pp. 971-978
    • Szyf, M.1
  • 2
    • 77953187081 scopus 로고    scopus 로고
    • Epigenetic signatures in cancer: Implications for the control of cancer in the clinic
    • Lima SC, Hernandez-Vargas H, Herceg Z. Epigenetic signatures in cancer: implications for the control of cancer in the clinic. Curr. Opin. Mol. Ther. 12(3), 316-324 (2010).
    • (2010) Curr. Opin. Mol. Ther. , vol.12 , Issue.3 , pp. 316-324
    • Lima, S.C.1    Hernandez-Vargas, H.2    Herceg, Z.3
  • 5
    • 79959666235 scopus 로고    scopus 로고
    • Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation
    • Dong E, Grayson DR, Guidotti A, Costa E. Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation. Epigenomics 1(1), 201-211 (2009).
    • (2009) Epigenomics , vol.1 , Issue.1 , pp. 201-211
    • Dong, E.1    Grayson, D.R.2    Guidotti, A.3    Costa, E.4
  • 6
    • 80054084433 scopus 로고    scopus 로고
    • Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies
    • Crea F, Nobili S, Paolicchi E et al. Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies. Drug Resist. Updat. 14(6), 280-296 (2011).
    • (2011) Drug Resist. Updat. , vol.14 , Issue.6 , pp. 280-296
    • Crea, F.1    Nobili, S.2    Paolicchi, E.3
  • 7
    • 80055038826 scopus 로고    scopus 로고
    • Circulating microRNAs as potential markers of human drug-induced liver injury
    • Starkey Lewis PJ, Dear J, Platt V et al. Circulating microRNAs as potential markers of human drug-induced liver injury. Hepatology 54(5), 1767-1776 (2011).
    • (2011) Hepatology , vol.54 , Issue.5 , pp. 1767-1776
    • Starkey Lewis, P.J.1    Dear, J.2    Platt, V.3
  • 8
    • 77954360116 scopus 로고    scopus 로고
    • Histone H1 null vertebrate cells exhibit altered nucleosome architecture
    • Hashimoto H, Takami Y, Sonoda E et al. Histone H1 null vertebrate cells exhibit altered nucleosome architecture. Nucleic Acids Res. 38(11), 3533-3545 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , Issue.11 , pp. 3533-3545
    • Hashimoto, H.1    Takami, Y.2    Sonoda, E.3
  • 10
    • 77957366305 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Kulis M, Esteller M. DNA methylation and cancer. Adv. Genet. 70, 27-56 (2010).
    • (2010) Adv. Genet. , vol.70 , pp. 27-56
    • Kulis, M.1    Esteller, M.2
  • 11
    • 32844459336 scopus 로고    scopus 로고
    • The Polycomb group protein EZH2 directly controls DNA methylation
    • Vire E, Brenner C, Deplus R et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439(7078), 871-874 (2006).
    • (2006) Nature , vol.439 , Issue.7078 , pp. 871-874
    • Vire, E.1    Brenner, C.2    Deplus, R.3
  • 12
    • 34247860920 scopus 로고    scopus 로고
    • Mechanisms of disease: Methyl-binding domain proteins as potential therapeutic targets in cancer
    • Sansom OJ, Maddison K, Clarke AR. Mechanisms of disease: methyl-binding domain proteins as potential therapeutic targets in cancer. Nat. Clin. Pract. Oncol. 4(5), 305-315 (2007).
    • (2007) Nat. Clin. Pract. Oncol. , vol.4 , Issue.5 , pp. 305-315
    • Sansom, O.J.1    Maddison, K.2    Clarke, A.R.3
  • 13
    • 65249157050 scopus 로고    scopus 로고
    • Epigenetics, DNA methylation, and chromatin modifying drugs
    • □ Overview of the classification and mechanisms of epigenetic drugs
    • Szyf M. Epigenetics, DNA methylation, and chromatin modifying drugs. Annu. Rev. Pharmacol. Toxicol. 49, 243-263 (2009). □ Overview of the classification and mechanisms of epigenetic drugs.
    • (2009) Annu. Rev. Pharmacol. Toxicol. , vol.49 , pp. 243-263
    • Szyf, M.1
  • 14
    • 79851502666 scopus 로고    scopus 로고
    • Histone acetylation-mediated glycosyltransferase gene regulation in mouse brain during development
    • Suzuki Y, Yanagisawa M, Ariga T, Yu RK. Histone acetylation-mediated glycosyltransferase gene regulation in mouse brain during development. J. Neurochem. 116(5), 874-880 (2011).
    • (2011) J. Neurochem. , vol.116 , Issue.5 , pp. 874-880
    • Suzuki, Y.1    Yanagisawa, M.2    Ariga, T.3    Yu, R.K.4
  • 15
    • 31344446955 scopus 로고    scopus 로고
    • Combination therapy with DNA methyltransferase inhibitors in hematologic malignancies
    • Gore SD. Combination therapy with DNA methyltransferase inhibitors in hematologic malignancies. Nat. Clin. Pract. Oncol. 2(Suppl. 1), S30-S35 (2005).
    • (2005) Nat. Clin. Pract. Oncol. , vol.2 , Issue.1 SUPPL.
    • Gore, S.D.1
  • 16
    • 36148950997 scopus 로고    scopus 로고
    • FDA approval summary: Vorinostat for treatment of advanced primary cutaneous T-cell lymphoma
    • Mann BS, Johnson JR, Cohen MH, Justice R, Pazdur R. FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma. Oncologist 12(10), 1247-1252 (2007).
    • (2007) Oncologist , vol.12 , Issue.10 , pp. 1247-1252
    • Mann, B.S.1    Johnson, J.R.2    Cohen, M.H.3    Justice, R.4    Pazdur, R.5
  • 17
    • 33749572938 scopus 로고    scopus 로고
    • Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
    • Hrzenjak A, Moinfar F, Kremser ML et al. Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells. Mol. Cancer Ther. 5(9), 2203-2210 (2006).
    • (2006) Mol. Cancer Ther. , vol.5 , Issue.9 , pp. 2203-2210
    • Hrzenjak, A.1    Moinfar, F.2    Kremser, M.L.3
  • 18
    • 79959582403 scopus 로고    scopus 로고
    • A pilot Phase II study of valproic acid for treatment of low-grade neuroendocrine carcinoma
    • Mohammed TA, Holen KD, Jaskula-Sztul R et al. A pilot Phase II study of valproic acid for treatment of low-grade neuroendocrine carcinoma. Oncologist 16(6), 835-843 (2011).
    • (2011) Oncologist , vol.16 , Issue.6 , pp. 835-843
    • Mohammed, T.A.1    Holen, K.D.2    Jaskula-Sztul, R.3
  • 19
    • 79251559363 scopus 로고    scopus 로고
    • Valproate-doxorubicin: Promising therapy for progressing mesothelioma. A Phase II study
    • Scherpereel A, Berghmans T, Lafitte JJ et al. Valproate-doxorubicin: promising therapy for progressing mesothelioma. A Phase II study. Eur. Respir. J. 37(1), 129-135 (2011).
    • (2011) Eur. Respir. J. , vol.37 , Issue.1 , pp. 129-135
    • Scherpereel, A.1    Berghmans, T.2    Lafitte, J.J.3
  • 20
    • 82955170653 scopus 로고    scopus 로고
    • Addition of a histone deacetylase inhibitor redirects tamoxifentreated breast cancer cells into apoptosis, which is opposed by the induction of autophagy
    • Thomas S, Thurn KT, Bicaku E, Marchion DC, Munster PN. Addition of a histone deacetylase inhibitor redirects tamoxifentreated breast cancer cells into apoptosis, which is opposed by the induction of autophagy. Breast Cancer Res. Treat. 130(2), 437-447 (2011).
    • (2011) Breast Cancer Res. Treat. , vol.130 , Issue.2 , pp. 437-447
    • Thomas, S.1    Thurn, K.T.2    Bicaku, E.3    Marchion, D.C.4    Munster, P.N.5
  • 21
    • 0019829051 scopus 로고
    • Mycotoxin production by Chaetomium spp. and related fungi
    • Sekita S, Yoshihira K, Natori S et al. Mycotoxin production by Chaetomium spp. and related fungi. Can. J. Microbiol. 27(8), 766-772 (1981).
    • (1981) Can. J. Microbiol. , vol.27 , Issue.8 , pp. 766-772
    • Sekita, S.1    Yoshihira, K.2    Natori, S.3
  • 22
    • 30644474460 scopus 로고    scopus 로고
    • Identification of a specific inhibitor of the histone methyltransferase SU (VAR) 3-9
    • Greiner D, Bonaldi T, Eskeland R, Roemer E, Imhof A. Identification of a specific inhibitor of the histone methyltransferase SU (VAR) 3-9. Nat. Chem. Biol. 1(3), 143-145 (2005).
    • (2005) Nat. Chem. Biol. , vol.1 , Issue.3 , pp. 143-145
    • Greiner, D.1    Bonaldi, T.2    Eskeland, R.3    Roemer, E.4    Imhof, A.5
  • 23
    • 84859643953 scopus 로고    scopus 로고
    • Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1
    • Chaib H, Nebbioso A, Prebet T et al. Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1. Leukemia 26(4), 662-674 (2011).
    • (2011) Leukemia , vol.26 , Issue.4 , pp. 662-674
    • Chaib, H.1    Nebbioso, A.2    Prebet, T.3
  • 24
    • 80855148233 scopus 로고    scopus 로고
    • The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response
    • Bernhard W, Barreto K, Saunders A, Dahabieh MS, Johnson P, Sadowski I. The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response. FEBS Lett. 585(22), 3549-3554 (2011).
    • (2011) FEBS Lett. , vol.585 , Issue.22 , pp. 3549-3554
    • Bernhard, W.1    Barreto, K.2    Saunders, A.3    Dahabieh, M.S.4    Johnson, P.5    Sadowski, I.6
  • 25
    • 82655179979 scopus 로고    scopus 로고
    • Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties
    • Wang J, Lu F, Ren Q et al. Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties. Cancer Res. 71(23), 7238-7249 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.23 , pp. 7238-7249
    • Wang, J.1    Lu, F.2    Ren, Q.3
  • 26
    • 84860340335 scopus 로고    scopus 로고
    • Lysine-specific histone demethylase 1 (LSD1): A potential molecular target for tumor therapy
    • Chen Y, Jie W, Yan W, Zhou K, Xiao Y. Lysine-specific histone demethylase 1 (LSD1): A potential molecular target for tumor therapy. Crit Rev. Eukaryot. Gene Expr. 22(1), 53-59 (2012).
    • (2012) Crit Rev. Eukaryot. Gene Expr. , vol.22 , Issue.1 , pp. 53-59
    • Chen, Y.1    Jie, W.2    Yan, W.3    Zhou, K.4    Xiao, Y.5
  • 27
    • 80052743686 scopus 로고    scopus 로고
    • Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors
    • Singh MM, Manton CA, Bhat KP et al. Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro. Oncol. 13(8), 894-903 (2011).
    • (2011) Neuro. Oncol. , vol.13 , Issue.8 , pp. 894-903
    • Singh, M.M.1    Manton, C.A.2    Bhat, K.P.3
  • 28
    • 80052519945 scopus 로고    scopus 로고
    • The huge world of small RNAs: Regulating networks of microRNAs (review)
    • Racz Z, Kaucsar T, Hamar P. The huge world of small RNAs: regulating networks of microRNAs (review). Acta Physiol Hung. 98(3), 243-251 (2011).
    • (2011) Acta Physiol Hung. , vol.98 , Issue.3 , pp. 243-251
    • Racz, Z.1    Kaucsar, T.2    Hamar, P.3
  • 29
    • 77957938117 scopus 로고    scopus 로고
    • Viruses, microRNAs, and host interactions
    • Skalsky RL, Cullen BR. Viruses, microRNAs, and host interactions. Annu. Rev. Microbiol. 64, 123-141 (2010).
    • (2010) Annu. Rev. Microbiol. , vol.64 , pp. 123-141
    • Skalsky, R.L.1    Cullen, B.R.2
  • 30
    • 34250201468 scopus 로고    scopus 로고
    • The role of microRNAs in cancer: No small matter
    • Wiemer EA. The role of microRNAs in cancer: no small matter. Eur. J. Cancer 43(10), 1529-1544 (2007).
    • (2007) Eur. J. Cancer , vol.43 , Issue.10 , pp. 1529-1544
    • Wiemer, E.A.1
  • 31
    • 77649133970 scopus 로고    scopus 로고
    • Mir-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts
    • □ Demonstrates the pleiotropic function of miRNAs. This study describes miRNA that traps the translational regulator poly rC - binding protein hnRNP E2 and thereby maintains the translation of CEBPA mRNA
    • Eiring AM, Harb JG, Neviani P et al. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell 140(5), 652-665 (2010). □ Demonstrates the pleiotropic function of miRNAs. This study describes miRNA that traps the translational regulator poly (rC) - binding protein hnRNP E2 and thereby maintains the translation of CEBPA mRNA.
    • (2010) Cell , vol.140 , Issue.5 , pp. 652-665
    • Eiring, A.M.1    Harb, J.G.2    Neviani, P.3
  • 32
    • 7744223490 scopus 로고    scopus 로고
    • MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNAs are required for methylation of the template chromosome
    • Bao N, Lye KW, Barton MK. MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNAs are required for methylation of the template chromosome. Dev. Cell 7(5), 653-662 (2004).
    • (2004) Dev. Cell , vol.7 , Issue.5 , pp. 653-662
    • Bao, N.1    Lye, K.W.2    Barton, M.K.3
  • 33
    • 77953957633 scopus 로고    scopus 로고
    • A codingindependent function of gene and pseudogene mRNAs regulates tumour biology
    • □ Demonstrates the impact of pseudogene mRNAs on miRNA function. A nontranslated mRNA of the pseudogene PTENP1 is reported as acting as a miRNA scavenger and regulates the expression of the tumor suppressor PTEN
    • Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A codingindependent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465(7301), 1033-1038 (2010). □ Demonstrates the impact of pseudogene mRNAs on miRNA function. A nontranslated mRNA of the pseudogene PTENP1 is reported as acting as a miRNA scavenger and regulates the expression of the tumor suppressor PTEN.
    • (2010) Nature , vol.465 , Issue.7301 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 34
    • 81155124251 scopus 로고    scopus 로고
    • MicroRNAs in the pathogenesis of cancer
    • Lovat F, Valeri N, Croce CM. MicroRNAs in the pathogenesis of cancer. Semin. Oncol. 38(6), 724-733 (2011).
    • (2011) Semin. Oncol. , vol.38 , Issue.6 , pp. 724-733
    • Lovat, F.1    Valeri, N.2    Croce, C.M.3
  • 36
    • 84855991876 scopus 로고    scopus 로고
    • Non-coding RNAs with essential roles in neurodegenerative disorders
    • Salta E, De Strooper B. Non-coding RNAs with essential roles in neurodegenerative disorders. Lancet Neurol. 11(2), 189-200 (2012).
    • (2012) Lancet Neurol. , vol.11 , Issue.2 , pp. 189-200
    • Salta, E.1    De Strooper, B.2
  • 37
    • 79958769268 scopus 로고    scopus 로고
    • Epigenetic aberrations during oncogenesis
    • Hatziapostolou M, Iliopoulos D. Epigenetic aberrations during oncogenesis. Cell Mol. Life Sci. 68(10), 1681-1702 (2011).
    • (2011) Cell Mol. Life Sci. , vol.68 , Issue.10 , pp. 1681-1702
    • Hatziapostolou, M.1    Iliopoulos, D.2
  • 38
    • 79551541972 scopus 로고    scopus 로고
    • Downregulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2
    • Smits M, Mir SE, Nilsson RJ et al. Downregulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2. PLoS ONE 6(1), e16282 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.1
    • Smits, M.1    Mir, S.E.2    Nilsson, R.J.3
  • 39
    • 81855200163 scopus 로고    scopus 로고
    • Non-coding RNAs in cancer initiation and progression and as novel biomarkers
    • Nana-Sinkam SP, Croce CM. Non-coding RNAs in cancer initiation and progression and as novel biomarkers. Mol. Oncol. 5(6), 483-491 (2011).
    • (2011) Mol. Oncol. , vol.5 , Issue.6 , pp. 483-491
    • Nana-Sinkam, S.P.1    Croce, C.M.2
  • 40
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • Kovalchuk O, Filkowski J, Meservy J et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol. Cancer Ther. 7(7), 2152-2159 (2008).
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3
  • 41
    • 77956648184 scopus 로고    scopus 로고
    • MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells
    • Li Z, Hu S, Wang J et al. MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells. Gynecol. Oncol. 119(1), 125-130 (2010).
    • (2010) Gynecol. Oncol. , vol.119 , Issue.1 , pp. 125-130
    • Li, Z.1    Hu, S.2    Wang, J.3
  • 42
    • 49149114863 scopus 로고    scopus 로고
    • Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
    • Zhu H, Wu H, Liu X et al. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem. Pharmacol. 76(5), 582-588 (2008).
    • (2008) Biochem. Pharmacol. , vol.76 , Issue.5 , pp. 582-588
    • Zhu, H.1    Wu, H.2    Liu, X.3
  • 43
    • 77956183846 scopus 로고    scopus 로고
    • Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma
    • Zhang H, Li M, Han Y et al. Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. Dig. Dis. Sci. 55(9), 2545-2551 (2010).
    • (2010) Dig. Dis. Sci. , vol.55 , Issue.9 , pp. 2545-2551
    • Zhang, H.1    Li, M.2    Han, Y.3
  • 44
    • 80053257151 scopus 로고    scopus 로고
    • Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia
    • Feng DD, Zhang H, Zhang P et al. Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia. J. Cell Mol. Med. 15(10), 2164-2175 (2011).
    • (2011) J. Cell Mol. Med. , vol.15 , Issue.10 , pp. 2164-2175
    • Feng, D.D.1    Zhang, H.2    Zhang, P.3
  • 45
    • 79951943718 scopus 로고    scopus 로고
    • Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells
    • Li X, Pan YZ, Seigel GM, Hu ZH, Huang M, Yu AM. Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. Biochem. Pharmacol. 81(6), 783-792 (2011).
    • (2011) Biochem. Pharmacol. , vol.81 , Issue.6 , pp. 783-792
    • Li, X.1    Pan, Y.Z.2    Seigel, G.M.3    Hu, Z.H.4    Huang, M.5    Yu, A.M.6
  • 46
    • 43949134440 scopus 로고    scopus 로고
    • MicroRNAs play a role in the development of human hematopoietic stem cells
    • Liao R, Sun J, Zhang L et al. MicroRNAs play a role in the development of human hematopoietic stem cells. J. Cell Biochem. 104(3), 805-817 (2008).
    • (2008) J. Cell Biochem. , vol.104 , Issue.3 , pp. 805-817
    • Liao, R.1    Sun, J.2    Zhang, L.3
  • 47
    • 66849113786 scopus 로고    scopus 로고
    • MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells
    • Pan YZ, Morris ME, Yu AM. MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells. Mol. Pharmacol. 75(6), 1374-1379 (2009).
    • (2009) Mol. Pharmacol. , vol.75 , Issue.6 , pp. 1374-1379
    • Pan, Y.Z.1    Morris, M.E.2    Yu, A.M.3
  • 48
    • 50249188925 scopus 로고    scopus 로고
    • Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line
    • To KK, Zhan Z, Litman T, Bates SE. Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line. Mol. Cell Biol. 28(17), 5147-5161 (2008).
    • (2008) Mol. Cell Biol. , vol.28 , Issue.17 , pp. 5147-5161
    • To, K.K.1    Zhan, Z.2    Litman, T.3    Bates, S.E.4
  • 49
    • 70350230378 scopus 로고    scopus 로고
    • Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2
    • To KK, Robey RW, Knutsen T, Zhan Z, Ried T, Bates SE. Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2. Mol. Cancer Ther. 8(10), 2959-2968 (2009).
    • (2009) Mol. Cancer Ther. , vol.8 , Issue.10 , pp. 2959-2968
    • To, K.K.1    Robey, R.W.2    Knutsen, T.3    Zhan, Z.4    Ried, T.5    Bates, S.E.6
  • 50
    • 85027922548 scopus 로고    scopus 로고
    • MicroRNA profiling in K-562 cells under imatinib treatment: Influence of miR-212 and miR-328 on ABCG2 expression
    • Turrini E, Haenisch S, Laechelt S, Diewock T, Bruhn O, Cascorbi I. MicroRNA profiling in K-562 cells under imatinib treatment: influence of miR-212 and miR-328 on ABCG2 expression. Pharmacogenet. Genomics 22(3), 198-205 (2012).
    • (2012) Pharmacogenet. Genomics , vol.22 , Issue.3 , pp. 198-205
    • Turrini, E.1    Haenisch, S.2    Laechelt, S.3    Diewock, T.4    Bruhn, O.5    Cascorbi, I.6
  • 51
    • 74149092809 scopus 로고    scopus 로고
    • Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1
    • Liang Z, Wu H, Xia J et al. Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1. Biochem. Pharmacol. 79(6), 817-824 (2010).
    • (2010) Biochem. Pharmacol. , vol.79 , Issue.6 , pp. 817-824
    • Liang, Z.1    Wu, H.2    Xia, J.3
  • 52
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI, Kovalchuk O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int. J. Cancer 127(8), 1785-1794 (2010).
    • (2010) Int. J. Cancer , vol.127 , Issue.8 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 53
    • 79955501601 scopus 로고    scopus 로고
    • *-mediated suppression of SOX2
    • □□ Demonstrates how a deregulated miRNA expression concurrently evokes stemness as well as chemoresistance via induction of ABC transporters in glioma cells
    • *-mediated suppression of SOX2. Cancer Res. 71(9), 3410-3421 (2011). □□ Demonstrates how a deregulated miRNA expression concurrently evokes stemness as well as chemoresistance via induction of ABC transporters in glioma cells.
    • (2011) Cancer Res. , vol.71 , Issue.9 , pp. 3410-3421
    • Jeon, H.M.1    Sohn, Y.W.2    Oh, S.Y.3
  • 54
    • 81255138201 scopus 로고    scopus 로고
    • Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5
    • Zhu Y, Yu F, Jiao Y et al. Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin. Cancer Res. 17(22), 7105-7115 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , Issue.22 , pp. 7105-7115
    • Zhu, Y.1    Yu, F.2    Jiao, Y.3
  • 55
    • 70349268327 scopus 로고    scopus 로고
    • MicroRNAs regulate CYP3A4 expression via direct and indirect targeting
    • Pan YZ, Gao W, Yu AM. MicroRNAs regulate CYP3A4 expression via direct and indirect targeting. Drug Metab. Dispos. 37(10), 2112-2117 (2009).
    • (2009) Drug Metab. Dispos. , vol.37 , Issue.10 , pp. 2112-2117
    • Pan, Y.Z.1    Gao, W.2    Yu, A.M.3
  • 56
    • 77950797711 scopus 로고    scopus 로고
    • MicroRNAs as gatekeepers of apoptosis
    • Subramanian S, Steer CJ. MicroRNAs as gatekeepers of apoptosis. J. Cell Physiol 223(2), 289-298 (2010).
    • (2010) J. Cell Physiol , vol.223 , Issue.2 , pp. 289-298
    • Subramanian, S.1    Steer, C.J.2
  • 57
    • 80555122819 scopus 로고    scopus 로고
    • Mir-146a suppresses the sensitivity to interferon-alpha in hepatocellular carcinoma cells
    • Tomokuni A, Eguchi H, Tomimaru Y et al. miR-146a suppresses the sensitivity to interferon-alpha in hepatocellular carcinoma cells. Biochem. Biophys. Res. Commun. 414(4), 675-680 (2011).
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , Issue.4 , pp. 675-680
    • Tomokuni, A.1    Eguchi, H.2    Tomimaru, Y.3
  • 58
    • 79961088478 scopus 로고    scopus 로고
    • MicroRNA-21 modulates chemosensitivity of breast cancer cells to doxorubicin by targeting PTEN
    • Wang ZX, Lu BB, Wang H, Cheng ZX, Yin YM. MicroRNA-21 modulates chemosensitivity of breast cancer cells to doxorubicin by targeting PTEN. Arch. Med. Res. 42(4), 281-290 (2011).
    • (2011) Arch. Med. Res. , vol.42 , Issue.4 , pp. 281-290
    • Wang, Z.X.1    Lu, B.B.2    Wang, H.3    Cheng, Z.X.4    Yin, Y.M.5
  • 59
    • 78651347241 scopus 로고    scopus 로고
    • Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line
    • Bai H, Xu R, Cao Z, Wei D, Wang C. Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line. FEBS Lett. 585(2), 402-408 (2011).
    • (2011) FEBS Lett. , vol.585 , Issue.2 , pp. 402-408
    • Bai, H.1    Xu, R.2    Cao, Z.3    Wei, D.4    Wang, C.5
  • 60
    • 79956313718 scopus 로고    scopus 로고
    • Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
    • Gong C, Yao Y, Wang Y et al. Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer. J. Biol. Chem. 286(21), 19127-19137 (2011).
    • (2011) J. Biol. Chem. , vol.286 , Issue.21 , pp. 19127-19137
    • Gong, C.1    Yao, Y.2    Wang, Y.3
  • 61
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: Mir-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V, Jung P, Verdoodt B et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6(13), 1586-1593 (2007).
    • (2007) Cell Cycle , vol.6 , Issue.13 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3
  • 62
    • 65549110908 scopus 로고    scopus 로고
    • Mir-34a as part of the resistance network in chronic lymphocytic leukemia
    • Zenz T, Mohr J, Eldering E et al. miR-34a as part of the resistance network in chronic lymphocytic leukemia. Blood 113(16), 3801-3808 (2009).
    • (2009) Blood , vol.113 , Issue.16 , pp. 3801-3808
    • Zenz, T.1    Mohr, J.2    Eldering, E.3
  • 63
    • 79954455860 scopus 로고    scopus 로고
    • Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas
    • Vogt M, Munding J, Gruner M et al. Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. Virchows Arch. 458(3), 313-322 (2011).
    • (2011) Virchows Arch. , vol.458 , Issue.3 , pp. 313-322
    • Vogt, M.1    Munding, J.2    Gruner, M.3
  • 64
    • 77956989411 scopus 로고    scopus 로고
    • MiR-34a attenuates paclitaxelresistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms
    • Kojima K, Fujita Y, Nozawa Y, Deguchi T, Ito M. MiR-34a attenuates paclitaxelresistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms. Prostate 70(14), 1501-1512 (2010).
    • (2010) Prostate , vol.70 , Issue.14 , pp. 1501-1512
    • Kojima, K.1    Fujita, Y.2    Nozawa, Y.3    Deguchi, T.4    Ito, M.5
  • 65
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27 (Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
    • le Sage C, Nagel R, Egan DA et al. Regulation of the p27 (Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J. 26(15), 3699-3708 (2007).
    • (2007) EMBO J. , vol.26 , Issue.15 , pp. 3699-3708
    • Le Sage, C.1    Nagel, R.2    Egan, D.A.3
  • 66
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • Miller TE, Ghoshal K, Ramaswamy B et al. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J. Biol. Chem. 283(44), 29897-29903 (2008).
    • (2008) J. Biol. Chem. , vol.283 , Issue.44 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3
  • 67
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • Zhao JJ, Lin J, Yang H et al. MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J. Biol. Chem. 283(45), 31079-31086 (2008).
    • (2008) J. Biol. Chem. , vol.283 , Issue.45 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3
  • 68
    • 79952281614 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
    • Rao X, Di Leva G, Li M et al. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene 30(9), 1082-1097 (2011).
    • (2011) Oncogene , vol.30 , Issue.9 , pp. 1082-1097
    • Rao, X.1    Di Leva, G.2    Li, M.3
  • 69
    • 44949249814 scopus 로고    scopus 로고
    • Mir-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
    • Xia L, Zhang D, Du R et al. miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int. J. Cancer 123(2), 372-379 (2008).
    • (2008) Int. J. Cancer , vol.123 , Issue.2 , pp. 372-379
    • Xia, L.1    Zhang, D.2    Du, R.3
  • 70
    • 84863276383 scopus 로고    scopus 로고
    • Mir-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2
    • Li H, Hui L, Xu W. miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2. Acta Biochim. Biophys. Sin. (Shanghai) 44(3), 269-277 (2012).
    • (2012) Acta Biochim. Biophys. Sin. (Shanghai) , vol.44 , Issue.3 , pp. 269-277
    • Li, H.1    Hui, L.2    Xu, W.3
  • 71
    • 77955619456 scopus 로고    scopus 로고
    • Mir-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines
    • Zhu W, Shan X, Wang T, Shu Y, Liu P. miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int. J. Cancer 127(11), 2520-2529 (2010).
    • (2010) Int. J. Cancer , vol.127 , Issue.11 , pp. 2520-2529
    • Zhu, W.1    Shan, X.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 72
    • 84859779031 scopus 로고    scopus 로고
    • Mir-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP
    • Zhu W, Xu H, Zhu D et al. miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. Cancer Chemother. Pharmacol. 69(3), 723-731 (2012).
    • (2012) Cancer Chemother. Pharmacol. , vol.69 , Issue.3 , pp. 723-731
    • Zhu, W.1    Xu, H.2    Zhu, D.3
  • 73
    • 84862888913 scopus 로고    scopus 로고
    • Mir-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2
    • Zhu W, Zhu D, Lu S et al. miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. Med. Oncol. 29(1), 384-391 (2012).
    • (2012) Med. Oncol. , vol.29 , Issue.1 , pp. 384-391
    • Zhu, W.1    Zhu, D.2    Lu, S.3
  • 74
    • 72449154270 scopus 로고    scopus 로고
    • Embryonic stem cell microRNAs: Defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?
    • Gunaratne PH. Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells? Curr. Stem Cell Res. Ther. 4(3), 168-177 (2009).
    • (2009) Curr. Stem Cell Res. Ther. , vol.4 , Issue.3 , pp. 168-177
    • Gunaratne, P.H.1
  • 75
    • 80052841078 scopus 로고    scopus 로고
    • MicroRNA regulation of cancer stem cells
    • Liu C, Tang DG. MicroRNA regulation of cancer stem cells. Cancer Res. 71(18), 5950-5954 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.18 , pp. 5950-5954
    • Liu, C.1    Tang, D.G.2
  • 76
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131(6), 1109-1123 (2007).
    • (2007) Cell , vol.131 , Issue.6 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3
  • 77
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138(3), 592-603 (2009).
    • (2009) Cell , vol.138 , Issue.3 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3
  • 78
    • 77951248184 scopus 로고    scopus 로고
    • E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells
    • Tryndyak VP, Beland FA, Pogribny IP. E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells. Int. J. Cancer 126(11), 2575-2583 (2010).
    • (2010) Int. J. Cancer , vol.126 , Issue.11 , pp. 2575-2583
    • Tryndyak, V.P.1    Beland, F.A.2    Pogribny, I.P.3
  • 79
    • 79952201744 scopus 로고    scopus 로고
    • Epigenetic regulation of microRNA expression in cancer
    • Choudhry H, Catto JW. Epigenetic regulation of microRNA expression in cancer. Methods Mol. Biol. 676, 165-184 (2011).
    • (2011) Methods Mol. Biol. , vol.676 , pp. 165-184
    • Choudhry, H.1    Catto, J.W.2
  • 80
    • 84855283939 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells
    • Rhodes LV, Nitschke AM, Segar HC et al. The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells. Oncol. Rep. 27(1), 10-16 (2012).
    • (2012) Oncol. Rep. , vol.27 , Issue.1 , pp. 10-16
    • Rhodes, L.V.1    Nitschke, A.M.2    Segar, H.C.3
  • 81
    • 80052316514 scopus 로고    scopus 로고
    • Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells
    • □□ Example of a methodological straightforward approach to elucidate the interaction between 5-aza-2'-deoxycytidine and suberoylanilide hydroxamic acid treatment, miR34a expression and regulation of stem cell characteristics in human pancreatic cancer stem cells
    • Nalls D, Tang SN, Rodova M, Srivastava RK, Shankar S. Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. PLoS ONE 6(8), e24099 (2011). □□ Example of a methodological straightforward approach to elucidate the interaction between 5-aza-2'-deoxycytidine and suberoylanilide hydroxamic acid treatment, miR34a expression and regulation of stem cell characteristics in human pancreatic cancer stem cells.
    • (2011) PLoS ONE , vol.6 , Issue.8
    • Nalls, D.1    Tang, S.N.2    Rodova, M.3    Srivastava, R.K.4    Shankar, S.5
  • 82
    • 82155183260 scopus 로고    scopus 로고
    • Epigenetic inactivation of the MIR34B/C in multiple myeloma
    • Wong KY, Yim RL, So CC, Jin DY, Liang R, Chim CS. Epigenetic inactivation of the MIR34B/C in multiple myeloma. Blood 118(22), 5901-5904 (2011).
    • (2011) Blood , vol.118 , Issue.22 , pp. 5901-5904
    • Wong, K.Y.1    Yim, R.L.2    So, C.C.3    Jin, D.Y.4    Liang, R.5    Chim, C.S.6
  • 83
    • 79960434259 scopus 로고    scopus 로고
    • MicroRNA-146a downregulates NFkappaB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma
    • Paik JH, Jang JY, Jeon YK et al. MicroRNA-146a downregulates NFkappaB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma. Clin. Cancer Res. 17(14), 4761-4771 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , Issue.14 , pp. 4761-4771
    • Paik, J.H.1    Jang, J.Y.2    Jeon, Y.K.3
  • 84
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res. 66(3), 1277-1281 (2006).
    • (2006) Cancer Res. , vol.66 , Issue.3 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3    Benz, S.C.4    Benz, C.C.5
  • 85
    • 72249107533 scopus 로고    scopus 로고
    • Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation
    • Li X, Liu J, Zhou R, Huang S, Huang S, Chen XM. Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. Br. J. Haematol. 148(1), 69-79 (2010).
    • (2010) Br. J. Haematol. , vol.148 , Issue.1 , pp. 69-79
    • Li, X.1    Liu, J.2    Zhou, R.3    Huang, S.4    Huang, S.5    Chen, X.M.6
  • 86
    • 44449149903 scopus 로고    scopus 로고
    • Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression
    • Bueno MJ, Pérez de Castro I, Gómez de Cedrón M et al. Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell 13(6), 496-506 (2008).
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 496-506
    • Bueno, M.J.1    Pérez De Castro, I.2    Gómez De Cedrón, M.3
  • 87
    • 84857411956 scopus 로고    scopus 로고
    • Anti-miR-203 Upregulates SOCS3 expression in breast cancer cells and enhances cisplatin chemosensitivity
    • Ru P, Steele R, Hsueh EC, Ray RB. Anti-miR-203 Upregulates SOCS3 expression in breast cancer cells and enhances cisplatin chemosensitivity. Genes Cancer 2(7), 720-727 (2011).
    • (2011) Genes Cancer , vol.2 , Issue.7 , pp. 720-727
    • Ru, P.1    Steele, R.2    Hsueh, E.C.3    Ray, R.B.4
  • 88
    • 64949159019 scopus 로고    scopus 로고
    • Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers
    • Zhou R, Yuan P, Wang Y et al. Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology 34(6), 1395-1405 (2009).
    • (2009) Neuropsychopharmacology , vol.34 , Issue.6 , pp. 1395-1405
    • Zhou, R.1    Yuan, P.2    Wang, Y.3
  • 89
    • 79960221018 scopus 로고    scopus 로고
    • Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379
    • Haenisch S, Laechelt S, Bruckmueller H et al. Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. Mol. Pharmacol. 80(2), 314-320 (2011).
    • (2011) Mol. Pharmacol. , vol.80 , Issue.2 , pp. 314-320
    • Haenisch, S.1    Laechelt, S.2    Bruckmueller, H.3
  • 90
    • 84859463669 scopus 로고    scopus 로고
    • Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells
    • Bao B, Wang Z, Ali S et al. Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells. Cancer Prev. Res. (Phila.) 5(3), 355-364 (2012).
    • (2012) Cancer Prev. Res. (Phila.) , vol.5 , Issue.3 , pp. 355-364
    • Bao, B.1    Wang, Z.2    Ali, S.3
  • 91
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: Rationale, strategies and challenges
    • □ Overview of how miRNAs and miRNA-based therapeutics could enlarge the arsenal of therapy options in cancer
    • Garzon R, Marcucci G, Croce CM. Targeting microRNAs in cancer: rationale, strategies and challenges. Nat. Rev. Drug Discov. 9(10), 775-789 (2010). □ Overview of how miRNAs and miRNA-based therapeutics could enlarge the arsenal of therapy options in cancer.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , Issue.10 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 92
    • 84655163371 scopus 로고    scopus 로고
    • Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer
    • Juergens RA, Wrangle J, Vendetti FP et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov. 1(7), 598-607 (2011).
    • (2011) Cancer Discov. , vol.1 , Issue.7 , pp. 598-607
    • Juergens, R.A.1    Wrangle, J.2    Vendetti, F.P.3
  • 93
    • 83055184277 scopus 로고    scopus 로고
    • RNA-directed epigenomic reprogramming: An emerging principle of a more targeted cancer therapy?
    • Moskalev EA, Schubert M, Hoheisel JD. RNA-directed epigenomic reprogramming: an emerging principle of a more targeted cancer therapy? Genes Chromosomes. Cancer 51(2), 105-110 (2012).
    • (2012) Genes Chromosomes. Cancer , vol.51 , Issue.2 , pp. 105-110
    • Moskalev, E.A.1    Schubert, M.2    Hoheisel, J.D.3
  • 94
    • 70350221952 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
    • Li Y, Guessous F, Zhang Y et al. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res. 69(19), 7569-7576 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.19 , pp. 7569-7576
    • Li, Y.1    Guessous, F.2    Zhang, Y.3
  • 95
    • 84855334413 scopus 로고    scopus 로고
    • MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells
    • Yamamura S, Saini S, Majid S et al. MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. PLoS ONE 7(1), e29722 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.1
    • Yamamura, S.1    Saini, S.2    Majid, S.3
  • 96
    • 84455194000 scopus 로고    scopus 로고
    • MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis
    • Shi L, Zhang S, Feng K et al. MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis. Int. J. Oncol. 40(1), 119-129 (2012).
    • (2012) Int. J. Oncol. , vol.40 , Issue.1 , pp. 119-129
    • Shi, L.1    Zhang, S.2    Feng, K.3
  • 97
    • 79955756373 scopus 로고    scopus 로고
    • Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL
    • Li X, Sanda T, Look AT, Novina CD, von Boehmer H. Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. J. Exp. Med. 208(4), 663-675 (2011).
    • (2011) J. Exp. Med. , vol.208 , Issue.4 , pp. 663-675
    • Li, X.1    Sanda, T.2    Look, A.T.3    Novina, C.D.4    Von Boehmer, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.