Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation

Journal of Molecular Medicine

Volumn 89, Issue 3, 2011, Pages 303-315

  Chen, Ching Hsein ^b   Chang, Yu Jia ^c,d   Ku, Maurice S B ^b   Chung, King Thom ^e   Yang, Jen Tsung ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e UNIVERSITY OF MEMPHIS   (United States)

Author keywords

Bax; Glioma; Glutathione depletion; Heme oxygenase 1; Temozolomide; Valproic acid

Indexed keywords

ACETYLCYSTEINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TEMOZOLOMIDE; TRANSCRIPTION FACTOR NF E2 P45 SUBUNIT; VALPROIC ACID;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; DRUG MECHANISM; DRUG POTENTIATION; GLIOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MONOTHERAPY; OXIDATION REDUCTION STATE; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; CELL LINE, TUMOR; DACARBAZINE; DRUG SYNERGISM; GLIOMA; HUMANS; OXIDATION-REDUCTION; VALPROIC ACID;

EID: 79955782730     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-010-0707-1     Document Type: Article

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