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Volumn 166, Issue , 2015, Pages 423-431

Cytotoxic and mutagenic in vitro assessment of two organosulfur compounds derived from onion to be used in the food industry

Author keywords

Caco 2 cell line; Dipropyl disulphide; Dipropyl sulphide; Essential oil; Onion

Indexed keywords

ANTIOXIDANTS; CELL CULTURE; CYTOTOXICITY; ESSENTIAL OILS; OILS AND FATS; OXYGEN;

EID: 84903825733     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2014.06.058     Document Type: Article
Times cited : (25)

References (39)
  • 2
    • 33644835000 scopus 로고    scopus 로고
    • Clarifying the real bioactive constituents of garlic
    • H. Amagase Clarifying the real bioactive constituents of garlic The Journal of Nutrition 136 3 2006 716S 725S (Pubitemid 43363763)
    • (2006) Journal of Nutrition , vol.136 , Issue.3
    • Amagase, H.1
  • 4
    • 0016151938 scopus 로고
    • Lipid lowering effect of allicin (diallyl disulfide oxide) on long-term feeding in normal rats
    • K.T. Augusti, and P.T. Mathew Lipid lowering effect of allicin (diallyl disulfide oxide) on long-term feeding in normal rats Experientia 30 1974 468 470
    • (1974) Experientia , vol.30 , pp. 468-470
    • Augusti, K.T.1    Mathew, P.T.2
  • 5
    • 0026066853 scopus 로고
    • 5-((3-Carboxyphenyl)-3-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)) tetrazolium, inner salt (MTS) and related analogs of 2-(4,5-dimethylthiazolyl)- 2,5-diphenylterazolium bromide (MTT) reducing to purple water soluble formazan as cell-viability indicators
    • J.A. Baltrop, T.C. Owen, A.H. Cory, and J.G. Cory 5-((3-Carboxyphenyl)-3- (4,5-dimethylthiazolyl)-3-(4-sulfophenyl)) tetrazolium, inner salt (MTS) and related analogs of 2-(4,5-dimethylthiazolyl)-2,5-diphenylterazolium bromide (MTT) reducing to purple water soluble formazan as cell-viability indicators Bioorganic and Medicinal Chemistry Letters 1 1991 611
    • (1991) Bioorganic and Medicinal Chemistry Letters , vol.1 , pp. 611
    • Baltrop, J.A.1    Owen, T.C.2    Cory, A.H.3    Cory, J.G.4
  • 6
    • 0344839038 scopus 로고    scopus 로고
    • Garlic as an antioxidant: The good, the bad and the ugly
    • DOI 10.1002/ptr.1281
    • S.K. Banerjee, P.K. Mukherjee, and S.K. Maulik Garlic as an antioxidant: the good, the bad and the ugly Phytotherapy Research 17 2003 97 106 (Pubitemid 36262255)
    • (2003) Phytotherapy Research , vol.17 , Issue.2 , pp. 97-106
    • Banerjee, S.K.1    Mukherjee, P.K.2    Maulik, S.K.3
  • 7
    • 1942504348 scopus 로고    scopus 로고
    • Antimicrobial activity of essential oil extracts of various onions (Allium cepa) and garlic (Allium sativum)
    • DOI 10.1016/j.lwt.2003.09.001
    • N. Benkeblia Antimicrobial activity of essential oil extracts of various onions (Allium cepa) and garlic (Allium sativum) Lebensmittel-Wissenschaft und Technologie-Food Science and Technology 37 2 2004 263 268 (Pubitemid 38504008)
    • (2004) LWT - Food Science and Technology , vol.37 , Issue.2 , pp. 263-268
    • Benkeblia, N.1
  • 8
    • 67651167463 scopus 로고    scopus 로고
    • Allium thiosulfinates: Chemistry, biological properties and their potential utilization in food preservation
    • N. Benkeblia, and V. Lanzotti Allium thiosulfinates: chemistry, biological properties and their potential utilization in food preservation Food 1 2007 193 201
    • (2007) Food , vol.1 , pp. 193-201
    • Benkeblia, N.1    Lanzotti, V.2
  • 9
    • 0022391554 scopus 로고
    • A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90)
    • DOI 10.1007/BF01666038
    • E. Borenfreund, and J.A. Puerner A simple quantitative procedure using monolayer culture for cytotoxicity assays Journal of Tissue Culture Methods 9 1984 7 9 (Pubitemid 15235618)
    • (1985) Journal of Tissue Culture Methods , vol.9 , Issue.1 , pp. 7-9
    • Borenfreund, E.1    Puerner, J.A.2
  • 10
    • 0017184389 scopus 로고
    • A rapid sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • M. Bradford A rapid sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 1976 248 254
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.1
  • 11
    • 84867743754 scopus 로고    scopus 로고
    • Modifications induced by the addition of a nanoclay in the functional and active properties of an EVOH film containing carvacrol for food packaging
    • J.P. Cerisuelo, J. Alonso, S. Aucejo, R. Gavara, and P. Hernandez-Muñoz Modifications induced by the addition of a nanoclay in the functional and active properties of an EVOH film containing carvacrol for food packaging Journal of Membrane Science 423-424 2012 247 256
    • (2012) Journal of Membrane Science , vol.423-424 , pp. 247-256
    • Cerisuelo, J.P.1    Alonso, J.2    Aucejo, S.3    Gavara, R.4    Hernandez-Muñoz, P.5
  • 12
    • 35548965077 scopus 로고    scopus 로고
    • Biological properties of onions and garlic
    • DOI 10.1016/j.tifs.2007.07.011, PII S0924224407002282
    • M. Corzo-Martínez, N. Corzo, and M. Villamiel Biological properties of onions and garlic Trends in Food Science and Technology 18 2007 609 625 (Pubitemid 350008034)
    • (2007) Trends in Food Science and Technology , vol.18 , Issue.12 , pp. 609-625
    • Corzo-Martinez, M.1    Corzo, N.2    Villamiel, M.3
  • 13
    • 33749679855 scopus 로고    scopus 로고
    • Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells
    • DOI 10.1016/j.jnutbio.2005.12.005, PII S0955286305003220
    • A. De Martino, G. Filomeni, K. Aquilano, M.R. Ciriolo, and G. Rotilio Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells Journal of Nutritional Biochemistry 17 2006 742 749 (Pubitemid 44557047)
    • (2006) Journal of Nutritional Biochemistry , vol.17 , Issue.11 , pp. 742-749
    • De Martino, A.1    Filomeni, G.2    Aquilano, K.3    Ciriolo, M.R.4    Rotilio, G.5
  • 14
    • 84903839646 scopus 로고    scopus 로고
    • Guidelines of the Scientific Committee on Food for the presentation of an application for safety assessment of a substance to be used in food contact materials prior to its authorisation (2001). Scientific Committee on Food, European Commission, Health & Consumer Protection Directorate-General
    • Guidelines of the Scientific Committee on Food for the presentation of an application for safety assessment of a substance to be used in food contact materials prior to its authorisation (2001). Scientific Committee on Food, European Commission, Health & Consumer Protection Directorate-General.
  • 15
    • 67651174488 scopus 로고    scopus 로고
    • Antiapoptotic effects of dietary antioxidants towards N-nitrosopiperidine and N-nitrosodibutylamine- induced apoptosis in HL-60 and HepG2 cells
    • A. García, P. Morales, N. Arranz, M.E. Delgado, J. Rafter, and A.I. Haza Antiapoptotic effects of dietary antioxidants towards N-nitrosopiperidine and N-nitrosodibutylamine- induced apoptosis in HL-60 and HepG2 cells Journal of Applied Toxicology 29 2009 403 413
    • (2009) Journal of Applied Toxicology , vol.29 , pp. 403-413
    • García, A.1    Morales, P.2    Arranz, N.3    Delgado, M.E.4    Rafter, J.5    Haza, A.I.6
  • 16
    • 0032917797 scopus 로고    scopus 로고
    • Modulation of phase II enzymes by organosulfur compounds from aliium vegetables in rat tissues
    • DOI 10.1006/taap.1998.8574
    • D. Guyonnet, M.H. Siess, A.M. Le Bon, and M. Suschetet Modulation of phase II enzymes by organosulfur compounds from Allium vegetables in rat tissues Toxicology and Applied Pharmacology 154 1999 50 58 (Pubitemid 29042599)
    • (1999) Toxicology and Applied Pharmacology , vol.154 , Issue.1 , pp. 50-58
    • Guyonnet, D.1    Siess, M.-H.2    Le Bon, A.-M.3    Suschetet, M.4
  • 19
    • 60849118364 scopus 로고    scopus 로고
    • The antioxidant glutathione in the fish cell lines EPC and BCF-2: Response to model pro-oxidants as measured by three different fluorescent dyes
    • A. Jos, A.M. Camean, S. Pflugmacher, and H. Segner The antioxidant glutathione in the fish cell lines EPC and BCF-2: response to model pro-oxidants as measured by three different fluorescent dyes Toxicology in Vitro 23 2009 546 553
    • (2009) Toxicology in Vitro , vol.23 , pp. 546-553
    • Jos, A.1    Camean, A.M.2    Pflugmacher, S.3    Segner, H.4
  • 20
    • 84884316191 scopus 로고    scopus 로고
    • Cytotoxic and anti-inflammatory effects of onion peel extract on lipopolysaccharide stimulated human colon carcinoma cells
    • J. Kim, J.S. Kim, and E. Park Cytotoxic and anti-inflammatory effects of onion peel extract on lipopolysaccharide stimulated human colon carcinoma cells Food and Chemical Toxicology 62 2013 199 204
    • (2013) Food and Chemical Toxicology , vol.62 , pp. 199-204
    • Kim, J.1    Kim, J.S.2    Park, E.3
  • 21
    • 33645829809 scopus 로고    scopus 로고
    • The analysis of onion and garlic
    • V. Lanzotti The analysis of onion and garlic Journal of Chromatography A 1112 2006 3 22
    • (2006) Journal of Chromatography A , vol.1112 , pp. 3-22
    • Lanzotti, V.1
  • 22
    • 0020533372 scopus 로고
    • Revised methods for the Salmonella mutagenicity test
    • D.M. Maron, and B.N. Ames Revised methods for the Salmonella mutagenicity test Mutation Research 113 1983 173 215 (Pubitemid 13120319)
    • (1983) Mutation Research , vol.113 , Issue.3-4 , pp. 173-215
    • Maron, D.M.1    Ames, B.N.2
  • 23
    • 79959454849 scopus 로고    scopus 로고
    • Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines
    • F. Merhi, J. Auger, F. Rendu, and B. Bauvois Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines Biologics 2 4 2008 885 895
    • (2008) Biologics , vol.2 , Issue.4 , pp. 885-895
    • Merhi, F.1    Auger, J.2    Rendu, F.3    Bauvois, B.4
  • 25
    • 36048967265 scopus 로고    scopus 로고
    • Acute and subacute toxic effects produced by microcystin-YR on the fish cell lines RTG-2 and PLHC-1
    • DOI 10.1016/j.tiv.2007.06.012, PII S0887233307001786
    • S. Pichardo, A. Jos, J.L. Zurita, M. Salguero, A.M. Cameán, and G. Repetto Acute and subacute toxic effects produced by microcystin-YR on the fish cell lines RTG-2 and PLHC-1 Toxicology in Vitro 21 2007 1460 1467 (Pubitemid 350086867)
    • (2007) Toxicology in Vitro , vol.21 , Issue.8 , pp. 1460-1467
    • Pichardo, S.1    Jos, A.2    Zurita, J.L.3    Salguero, M.4    Camean, A.M.5    Repetto, G.6
  • 26
    • 72749122904 scopus 로고    scopus 로고
    • Differential oxidative stress responses to pure Microcystin-LR and Microcystin-containing and non-containing cyanobacterial crude extracts on Caco-2 cells
    • M. Puerto, S. Pichardo, A. Jos, A.I. Prieto, E. Sevilla, and J.E. Frias et al. Differential oxidative stress responses to pure Microcystin-LR and Microcystin-containing and non-containing cyanobacterial crude extracts on Caco-2 cells Toxicon 55 2010 514 522
    • (2010) Toxicon , vol.55 , pp. 514-522
    • Puerto, M.1    Pichardo, S.2    Jos, A.3    Prieto, A.I.4    Sevilla, E.5    Frias, J.E.6
  • 27
    • 83955163674 scopus 로고    scopus 로고
    • Characterization and antimicrobial activity studies of polypropylene films with carvacrol and thymol for active packaging
    • M. Ramos, A. Jiménez, M. Peltzer, and M.C. Garrigós Characterization and antimicrobial activity studies of polypropylene films with carvacrol and thymol for active packaging Journal of Food Engineering 109 2012 513 519
    • (2012) Journal of Food Engineering , vol.109 , pp. 513-519
    • Ramos, M.1    Jiménez, A.2    Peltzer, M.3    Garrigós, M.C.4
  • 28
    • 77953484782 scopus 로고    scopus 로고
    • Chemical compositions, antiviral and antioxidant activities of seven essential oils
    • R.M. Romeilah, S.A. Fayed, and G.I. Mahmoud Chemical compositions, antiviral and antioxidant activities of seven essential oils Journal of Applied Sciences Research 6 1 2010 50 62
    • (2010) Journal of Applied Sciences Research , vol.6 , Issue.1 , pp. 50-62
    • Romeilah, R.M.1    Fayed, S.A.2    Mahmoud, G.I.3
  • 30
    • 0034634761 scopus 로고    scopus 로고
    • Garlic and onion oils inhibit proliferation and induce differentiation of HL-60 cells
    • T. Seki, K. Tsuji, Y. Hayato, T. Moritomo, and T. Ariga Garlic and onion oils inhibit proliferation and induce differentiation of HL-60 cells Cancer Letters 160 2000 29 35
    • (2000) Cancer Letters , vol.160 , pp. 29-35
    • Seki, T.1    Tsuji, K.2    Hayato, Y.3    Moritomo, T.4    Ariga, T.5
  • 31
    • 77949568185 scopus 로고    scopus 로고
    • Diallyl sulfide induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway
    • H.A. Shin, Y.Y. Cha, M.S. Park, J.M. Kim, and Y.C. Lim Diallyl sulfide induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway Oral Oncology 46 2010 e15 e18
    • (2010) Oral Oncology , vol.46
    • Shin, H.A.1    Cha, Y.Y.2    Park, M.S.3    Kim, J.M.4    Lim, Y.C.5
  • 32
    • 1542316326 scopus 로고    scopus 로고
    • Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions
    • M.Y. Shon, S.D. Choi, G.G. Kahng, S.H. Nam, and N.K. Sung Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions Food and Chemical Toxicology 42 2004 659 666
    • (2004) Food and Chemical Toxicology , vol.42 , pp. 659-666
    • Shon, M.Y.1    Choi, S.D.2    Kahng, G.G.3    Nam, S.H.4    Sung, N.K.5
  • 33
    • 0029872293 scopus 로고    scopus 로고
    • Diallyl disulfide suppresses the growth of human colon tumor cell xenografts in athymic nude mice
    • S.G. Sundaram, and J.A. Milner Diallyl disulfide suppresses the growth of human colon tumor cell xenografts in athymic nude mice The Journal of Nutrition 126 1996 1355 1361 (Pubitemid 26137695)
    • (1996) Journal of Nutrition , vol.126 , Issue.5 , pp. 1355-1361
    • Sundaram, S.C.1    Milner, J.A.2
  • 34
    • 57849144828 scopus 로고    scopus 로고
    • Chemical compositions and antioxidant/anti-inflammatory activities of steam distillate from freeze-dried onion (Allium cepa L.) sprout
    • M. Takahashi, and T. Shibamoto Chemical compositions and antioxidant/anti-inflammatory activities of steam distillate from freeze-dried onion (Allium cepa L.) sprout Journal of Agricultural and Food Chemistry 56 2008 10462 10467
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , pp. 10462-10467
    • Takahashi, M.1    Shibamoto, T.2
  • 35
    • 84885300285 scopus 로고    scopus 로고
    • Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes
    • C.Y. Tsai, C.C. Wang, T.Y. Lai, T.Y. Tsu, C.H. Wang, and H.Y. Liang et al. Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes International Journal of Cardiology 168 2013 1286 1297
    • (2013) International Journal of Cardiology , vol.168 , pp. 1286-1297
    • Tsai, C.Y.1    Wang, C.C.2    Lai, T.Y.3    Tsu, T.Y.4    Wang, C.H.5    Liang, H.Y.6
  • 36
    • 34547232140 scopus 로고    scopus 로고
    • Antioxidant, anti-inflammatory, and antimicrobial properties of garlic and onions
    • DOI 10.1108/00346650710749071
    • E.A. Wilson, and B. Demmig-Adams Antioxidant, anti-inflammatory, and antimicrobial properties of garlic and onions Nutrition and Food Science 37 3 2007 178 183 (Pubitemid 47108333)
    • (2007) Nutrition and Food Science , vol.37 , Issue.3 , pp. 178-183
    • Wilson, E.A.1    Demmig-Adams, B.2
  • 37
    • 3342895063 scopus 로고    scopus 로고
    • Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2
    • DOI 10.1038/sj.onc.1207747
    • D. Xiao, S. Choi, D.E. Johnson, V.G. Vogel, C.S. Johnson, and D.L. Trump et al. Diallyl trisulfide induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2 Oncogene 23 2004 5594 5606 (Pubitemid 39093037)
    • (2004) Oncogene , vol.23 , Issue.33 , pp. 5594-5606
    • Xiao, D.1    Choi, S.2    Johnson, D.E.3    Vogel, V.G.4    Johnson, C.S.5    Trump, D.L.6    Lee, Y.J.7    Singh, S.V.8
  • 38
    • 84866554026 scopus 로고    scopus 로고
    • Antimicrobial and antioxidant activities of the essential oil from onion (Allium cepa L.)
    • C.H. Ye, D.H. Dai, and W.L. Hu Antimicrobial and antioxidant activities of the essential oil from onion (Allium cepa L.) Food Control 30 2013 48 53
    • (2013) Food Control , vol.30 , pp. 48-53
    • Ye, C.H.1    Dai, D.H.2    Hu, W.L.3
  • 39
    • 0025119450 scopus 로고
    • Neutral red (NR) assay for cell viability and xenobiotic-induced cytotoxicity in primary cultures of human and rat hepatocytes
    • S.Z. Zhang, M.M. Lipsky, B.F. Trump, and I.C. Hsu Neutral red (NR) assay for cell viability and xenobiotic-induced cytotoxicity in primary cultures of human and rat hepatocytes Cell Biology and Toxicology 6 1990 219 234 (Pubitemid 20331326)
    • (1990) Cell Biology and Toxicology , vol.6 , Issue.2 , pp. 219-234
    • Zhang, S.-Z.1    Lipsky, M.M.2    Trump, B.F.3    Hsu, I.-C.4


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