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Volumn 31, Issue 13, 2014, Pages 1129-1138

Linking traumatic brain injury to chronic traumatic encephalopathy: Identification of potential mechanisms leading to neurofibrillary tangle development

Author keywords

chronic traumatic encephalopathy; neurofibrillary tangles

Indexed keywords

CYCLIN DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE C; TAR DNA BINDING PROTEIN; TAU PROTEIN;

EID: 84903823140     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2013.3303     Document Type: Review
Times cited : (103)

References (99)
  • 2
    • 78149437916 scopus 로고    scopus 로고
    • Chronic traumatic encephalopathy: A potential late effect of sport-related concussive and subconcussive head trauma
    • Gavett, B.E., Stern, R.A., and McKee, A.C. (2011). Chronic traumatic encephalopathy: A potential late effect of sport-related concussive and subconcussive head trauma. Clin. Sports Med. 30, 179-188
    • (2011) Clin. Sports Med , vol.30 , pp. 179-188
    • Gavett, B.E.1    Stern, R.A.2    McKee, A.C.3
  • 3
    • 82455188194 scopus 로고    scopus 로고
    • Long-Term consequences of repetitive brain trauma: Chronic traumatic encephalopathy
    • Stern, R.A., Riley, D.O., Daneshvar, D.H., Nowinski, C.J., Cantu, R.C., and McKee, A.C. (2011). Long-Term consequences of repetitive brain trauma: Chronic traumatic encephalopathy. PM R 3, S460-S467
    • (2011) PMR , vol.3
    • Stern, R.A.1    Riley, D.O.2    Daneshvar, D.H.3    Nowinski, C.J.4    Cantu, R.C.5    McKee, A.C.6
  • 5
    • 84874588802 scopus 로고    scopus 로고
    • Military- and sports-related mild traumatic brain injury: Clinical presentation, management, and long-Term consequences
    • Peskind, E.R., Brody, D., Cernak, I., McKee, A., and Ruff, R.L. (2013). Military- And sports-related mild traumatic brain injury: Clinical presentation, management, and long-Term consequences. J. Clin. Psychiatry 74, 180-188
    • (2013) J. Clin. Psychiatry , vol.74 , pp. 180-188
    • Peskind, E.R.1    Brody, D.2    Cernak, I.3    McKee, A.4    Ruff, R.L.5
  • 8
    • 79958169814 scopus 로고    scopus 로고
    • Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology
    • Spillantini, M.G., Lovino, M., and Vuono, R. (2011). Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology. Arch. Ital. Biol. 149, 215-223
    • (2011) Arch. Ital. Biol , vol.14 , pp. 215-223
    • Spillantini, M.G.1    Lovino, M.2    Vuono, R.3
  • 9
  • 11
    • 84875187992 scopus 로고    scopus 로고
    • Chronic traumatic encephalopathy - Neuropathology in athletes and war veterans
    • Lakis, N., Corona, R.J., Toshkezi, G., and Chin, L.S. (2013). Chronic traumatic encephalopathy - neuropathology in athletes and war veterans. Neurol. Res. 35, 290-299
    • (2013) Neurol. Res , vol.35 , pp. 290-299
    • Lakis, N.1    Corona, R.J.2    Toshkezi, G.3    Chin, L.S.4
  • 12
    • 84883502350 scopus 로고    scopus 로고
    • Hyperphosphorylation-induced tau oligomers
    • Iqbal, K., Gong, C.X., and Liu, F. (2013). Hyperphosphorylation-induced tau oligomers. Front. Neurol. 4, 112-118
    • (2013) Front. Neurol , vol.4 , pp. 12-118
    • Iqbal, K.1    Gong, C.X.2    Liu, F.3
  • 14
    • 84897365237 scopus 로고    scopus 로고
    • Molecular mechanisms of cognitive dysfunction following traumatic brain injury
    • Walker, K.R., and Tesco, G. (2013). Molecular mechanisms of cognitive dysfunction following traumatic brain injury. Front. Aging Neurosci. 5, 29-43
    • (2013) Front. Aging Neurosci , vol.5 , pp. 9-43
    • Walker, K.R.1    Tesco, G.2
  • 15
    • 84883503648 scopus 로고    scopus 로고
    • Are tau aggregates toxic or protective in Tauopathies?
    • Cowan, C.M., and Mudher, A. (2013). Are tau aggregates toxic or protective in Tauopathies?. Front. Neurol. 4, 114-118
    • (2013) Front. Neurol , vol.4 , pp. 14-118
    • Cowan, C.M.1    Mudher, A.2
  • 18
    • 84980053087 scopus 로고    scopus 로고
    • Multiple mechanisms of extracellular tau spreading in a non-Transgenic tauopathy model
    • Le, M.N., Kim, W., Lee, S., McKee, A.C., and Hall, G.F. (2012). Multiple mechanisms of extracellular tau spreading in a non-Transgenic tauopathy model. Am. J. Neurodegener. Dis. 1, 316-333
    • (2012) Am. J. Neurodegener. Dis , vol.1 , pp. 16-333
    • Le, M.N.1    Kim, W.2    Lee, S.3    McKee, A.C.4    Hall, G.F.5
  • 19
    • 84873615689 scopus 로고    scopus 로고
    • Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6
    • Hebron, M.L., Lonskaya, I., Sharpe, K., Weerasinghe, P.P., Algarzae, N.K., Shekoyan, A.R., and Moussa, C.E. (2013). Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6). J. Biol. Chem. 288, 4103-4115
    • (2013) J. Biol. Chem , vol.28 , pp. 4103-4115
    • Hebron, M.L.1    Lonskaya, I.2    Sharpe, K.3    Weerasinghe, P.P.4    Algarzae, N.K.5    Shekoyan, A.R.6    Moussa, C.E.7
  • 24
    • 70349171800 scopus 로고    scopus 로고
    • Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain
    • Hochman, S., Wang, W., Wang, W., Mei, X., Huang, J., Wei, Y., Wang, Y., Wu, S., and Li, Y. (2009). Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain. PLoS ONE 4, e6973
    • (2009) PLoS ONE , vol.4
    • Hochman, S.1    Wang, W.2    Wang, W.3    Mei, X.4    Huang, J.5    Wei, Y.6    Wang, Y.7    Wu, S.8    Li, Y.9
  • 26
    • 84884257774 scopus 로고    scopus 로고
    • Distinct patterns of expression of traumatic brain injury biomarkers after blast exposure: Role of compromised cell membrane integrity
    • Arun, P., Abu-Taleb, R., Oguntayo, S., Tanaka, M., Wang, Y., Valiyaveettil, M., Long, J.B., Zhang, Y., and Nambiar, M.P. (2013). Distinct patterns of expression of traumatic brain injury biomarkers after blast exposure: Role of compromised cell membrane integrity. Neurosci. Lett. 552, 87-91
    • (2013) Neurosci. Lett , vol.55 , pp. 87-91
    • Arun, P.1    Abu-Taleb, R.2    Oguntayo, S.3    Tanaka, M.4    Wang, Y.5    Valiyaveettil, M.6    Long, J.B.7    Zhang, Y.8    Nambiar, M.P.9
  • 28
    • 0346728670 scopus 로고    scopus 로고
    • Neurotoxicity, oxidative stress and cerebrovascular disorders
    • Qureshi, G.A., Baig, S., Sarwar, M., and Parvez, S.H. (2004). Neurotoxicity, oxidative stress and cerebrovascular disorders. Neurotoxicology 25, 121-138
    • (2004) Neurotoxicology , vol.25 , pp. 121-138
    • Qureshi, G.A.1    Baig, S.2    Sarwar, M.3    Parvez, S.H.4
  • 29
    • 84879513391 scopus 로고    scopus 로고
    • Astrocyte-specific overexpression of insulin-like growth factor-1 protects hippocampal neurons and reduces behavioral deficits following traumatic brain injury in mice
    • Madathil, S.K., Carlson, S.W., Brelsfoard, J.M., Ye, P., D'Ercole, A.J., and Saatman, K.E. (2013). Astrocyte-specific overexpression of insulin-like growth factor-1 protects hippocampal neurons and reduces behavioral deficits following traumatic brain injury in mice. PLoS One 8, e67204
    • (2013) PLoS One , vol.8
    • Madathil, S.K.1    Carlson, S.W.2    Brelsfoard, J.M.3    Ye, P.4    D'Ercole, A.J.5    Saatman, K.E.6
  • 30
    • 84886898223 scopus 로고    scopus 로고
    • Distinct activation profiles in microglia of different ages: A systematic study in isolated embryonic to aged microglial cultures
    • Lai, A.Y., Dibal, C.D., Armitage, G.A., Winship, I.R., and Todd, K.G. (2013). Distinct activation profiles in microglia of different ages: A systematic study in isolated embryonic to aged microglial cultures. Neuroscience 254, 185-195
    • (2013) Neuroscience , vol.254 , pp. 185-195
    • Lai, A.Y.1    Dibal, C.D.2    Armitage, G.A.3    Winship, I.R.4    Todd, K.G.5
  • 31
    • 84871896555 scopus 로고    scopus 로고
    • Long-Term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model
    • Acosta, S.A., Tajiri, N., Shinozuka, K., Ishikawa, H., Grimmig, B., Diamond, D., Sanberg, P.R., Bickford, P.C., Kaneko, Y., and Borlongan, C.V. (2013). Long-Term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model. PLoS One 8, e53376
    • (2013) PLoS One , vol.8
    • Acosta, S.A.1    Tajiri, N.2    Shinozuka, K.3    Ishikawa, H.4    Grimmig, B.5    Diamond, D.6    Sanberg, P.R.7    Bickford, P.C.8    Kaneko, Y.9    Borlongan, C.V.10
  • 33
    • 84873452455 scopus 로고    scopus 로고
    • Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states
    • Kumar, A., Stoica, B.A., Sabirzhanov, B., Burns, M.P., Faden, A.I., and Loane, D.J. (2013). Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol. Aging 34, 1397-1411
    • (2013) Neurobiol. Aging , vol.34 , pp. 1397-1411
    • Kumar, A.1    Stoica, B.A.2    Sabirzhanov, B.3    Burns, M.P.4    Faden, A.I.5    Loane, D.J.6
  • 34
    • 84872689693 scopus 로고    scopus 로고
    • Review: The long-Term consequences of microglial activation following acute traumatic brain injury
    • Smith, C. (2013). Review: The long-Term consequences of microglial activation following acute traumatic brain injury. Neuropathol. Appl. Neurobiol. 39, 35-44
    • (2013) Neuropathol. Appl. Neurobiol , vol.39 , pp. 35-44
    • Smith, C.1
  • 36
    • 84878945320 scopus 로고    scopus 로고
    • Transsplicing correction of tau isoform imbalance in a mouse model of tau mis-splicing
    • Avale, M.E., Rodriguez-Martin, T., and Gallo, J.M. (2013). Transsplicing correction of tau isoform imbalance in a mouse model of tau mis-splicing. Hum. Mol. Genet. 22, 2603-2611
    • (2013) Hum. Mol. Genet , vol.22 , pp. 2603-2611
    • Avale, M.E.1    Rodriguez-Martin, T.2    Gallo, J.M.3
  • 37
    • 84881494867 scopus 로고    scopus 로고
    • Interactions between Aß and mutated tau lead to polymorphism and induce aggregation of aß-mutated tau oligomeric complexes
    • Agarwal, P.K., Raz, Y., and Miller, Y. (2013). Interactions between Aß and mutated tau lead to polymorphism and induce aggregation of aß-mutated tau oligomeric complexes. PLoS ONE 8, e73303
    • (2013) PLoS ONE , vol.8
    • Agarwal, P.K.1    Raz, Y.2    Miller, Y.3
  • 38
    • 0038292060 scopus 로고    scopus 로고
    • Isoforms changes of tau protein during development in various species
    • Takuma, H., Arawaka, S., and Mori, H. (2003). Isoforms changes of tau protein During development in various species. Dev. Brain Res. 142, 121-127
    • (2003) Dev. Brain Res , vol.1 , pp. 121-127
    • Takuma, H.1    Arawaka, S.2    Mori, H.3
  • 39
    • 64949087565 scopus 로고    scopus 로고
    • Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3f protein
    • Sadik, G., Tanaka, T., Kato, K., Yanagi, K., Kudo, T., and Takeda, M. (2009). Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3f protein. Biochem. Biophys. Res. Commun. 383, 37-41
    • (2009) Biochem. Biophys. Res. Commun , vol.3 , pp. 37-41
    • Sadik, G.1    Tanaka, T.2    Kato, K.3    Yanagi, K.4    Kudo, T.5    Takeda, M.6
  • 40
    • 0026711059 scopus 로고
    • Fetal-Type phosphorylation of the tau in paired helical filament
    • Kanemaru, K., Takio, K., Miura, R., Titani, K., and Ihara, Y. (1992). Fetal-Type phosphorylation of the tau in paired helical filament. J. Neurochem. 58, 1667-1675
    • (1992) J. Neurochem , vol.5 , pp. 1667-1675
    • Kanemaru, K.1    Takio, K.2    Miura, R.3    Titani, K.4    Ihara, Y.5
  • 41
    • 0031007546 scopus 로고    scopus 로고
    • Regulated phosphorylation and dephosphorylation of tau protein: Effects on microtubule interaction, intracellular trafficking and neurodegeneration
    • Billingsley, M.L., and Kincaid, R.L. (1997). Regulated phosphorylation and dephosphorylation of tau protein: Effects on microtubule interaction, intracellular trafficking and neurodegeneration. Biochem. J. 323, 577-591
    • (1997) Biochem. J , vol.323 , pp. 577-591
    • Billingsley, M.L.1    Kincaid, R.L.2
  • 42
    • 0034598963 scopus 로고    scopus 로고
    • Inactivation of glycogen synthase kinase-3 by protein kinase C d: Implications for regulation of s phosphorylation
    • Tsujio, I., Tanaka, T., Kudo, T., Nishikawa, T., Shinozaki, K., Grundke-Iqbal, I., Iqbal, K., and Takeda, M. (2000). Inactivation of glycogen synthase kinase-3 by protein kinase C d: Implications for regulation of s phosphorylation. FEBS Lett. 469, 111-117
    • (2000) FEBS Lett , vol.4 , pp. 111-117
    • Tsujio, I.1    Tanaka, T.2    Kudo, T.3    Nishikawa, T.4    Shinozaki, K.5    Grundke-Iqbal, I.6    Iqbal, K.7    Takeda, M.8
  • 43
    • 77956920667 scopus 로고    scopus 로고
    • Icariin attenuates b-Amyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells
    • Zeng, K., Ko, H., Yang, H.O., and Wang, X. (2010). Icariin attenuates b-Amyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells. Neuropharmacology 59, 542-550
    • (2010) Neuropharmacology , vol.59 , pp. 542-550
    • Zeng, K.1    Ko, H.2    Yang, H.O.3    Wang, X.4
  • 44
    • 84874607578 scopus 로고    scopus 로고
    • Rapamycin Decreases tau phosphorylation at Ser214 through regulation of cAMP-dependent kinase
    • Liu, Y., Su, Y., Wang, J., Sun, S., Wang, T., Qiao, X., Run, X., Li, H., and Liang, Z. (2013). Rapamycin Decreases tau phosphorylation at Ser214 through regulation of cAMP-dependent kinase. Neurochem. Int. 62, 458-467
    • (2013) Neurochem. Int , vol.62 , pp. 458-467
    • Liu, Y.1    Su, Y.2    Wang, J.3    Sun, S.4    Wang, T.5    Qiao, X.6    Run, X.7    Li, H.8    Liang, Z.9
  • 45
    • 84880354954 scopus 로고    scopus 로고
    • Involvement of extracellular signal regulated kinases in traumatic brain injury-induced depression in rodents
    • Kuo, J.R., Cheng, Y.H., Chen, Y.S., Chio, C.C., and Gean, P.W. (2013). Involvement of extracellular signal regulated kinases in traumatic brain injury-induced depression in rodents. J. Neurotrauma 30, 1223-1231
    • (2013) J. Neurotrauma , vol.30 , pp. 1223-1231
    • Kuo, J.R.1    Cheng, Y.H.2    Chen, Y.S.3    Chio, C.C.4    Gean, P.W.5
  • 46
    • 84865318675 scopus 로고    scopus 로고
    • Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo
    • Zhao, Y., Luo, P., Guo, Q., Li, S., Zhang, L., Zhao, M., Xu, H., Yang, Y., Poon, W., and Fei, Z. (2012). Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo. Exp. Neurol. 237, 489-498
    • (2012) Exp. Neurol , vol.23 , pp. 489-498
    • Zhao, Y.1    Luo, P.2    Guo, Q.3    Li, S.4    Zhang, L.5    Zhao, M.6    Xu, H.7    Yang, Y.8    Poon, W.9    Fei, Z.10
  • 48
    • 34247549624 scopus 로고    scopus 로고
    • Alterations in mammalian target of rapamycin signaling pathways after traumatic brain injury
    • Chen, S., Atkins, C.M., Liu, C.L., Alonso, O.F., Dietrich, W.D., and Hu, B.R. (2007). Alterations in mammalian target of rapamycin signaling pathways after traumatic brain injury. J. Cereb. Blood Flow Metab. 27, 939-949
    • (2007) J. Cereb. Blood Flow Metab , vol.2 , pp. 939-949
    • Chen, S.1    Atkins, C.M.2    Liu, C.L.3    Alonso, O.F.4    Dietrich, W.D.5    Hu, B.R.6
  • 49
    • 84890308707 scopus 로고    scopus 로고
    • Spatiotemporal patterns and essential role of msk1 expression after rat spinal cord injury
    • Li, Z., Zhao, L., Hang, H., Zhu, N., Ning, B., and Lv, Z. (2013). Spatiotemporal patterns and essential role of msk1 expression after rat spinal cord injury. Neurochem Res 38, 2581-2587
    • (2013) Neurochem Res , vol.38 , pp. 2581-2587
    • Li, Z.1    Zhao, L.2    Hang, H.3    Zhu, N.4    Ning, B.5    Lv, Z.6
  • 51
    • 79952281612 scopus 로고    scopus 로고
    • Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton
    • Kramerov, A.A., Golub, A.G., Bdzhola, V.G., Yarmoluk, S.M., Ahmed, K., Bretner, M., and Ljubimov, A.V. (2011). Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton. Mol. Cell Biochem. 349, 125-137
    • (2011) Mol. Cell Biochem , vol.34 , pp. 125-137
    • Kramerov, A.A.1    Golub, A.G.2    Bdzhola, V.G.3    Yarmoluk, S.M.4    Ahmed, K.5    Bretner, M.6    Ljubimov, A.V.7
  • 52
    • 84882266694 scopus 로고    scopus 로고
    • Upregulation of CRM1 relates to neuronal apoptosis after traumatic brain injury in adult rats
    • Li, A., Zou, F., Fu, H., Cui, G., Yan, Y., Wu, Q., and Gu, X. (2013). Upregulation of CRM1 relates to neuronal apoptosis after traumatic brain injury in adult rats. J. Mol. Neurosci. 51, 208-218
    • (2013) J. Mol. Neurosci , vol.51 , pp. 208-218
    • Li, A.1    Zou, F.2    Fu, H.3    Cui, G.4    Yan, Y.5    Wu, Q.6    Gu, X.7
  • 53
    • 84855360054 scopus 로고    scopus 로고
    • Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma
    • Kabadi, S.V., Stoica, B.A., Byrnes, K.R., Hanscom, M., Loane, D.J., and Faden, A.I. (2012). Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. J. Cereb. Blood Flow Metab. 32, 137-149
    • (2012) J. Cereb. Blood Flow Metab , vol.32 , pp. 137-149
    • Kabadi, S.V.1    Stoica, B.A.2    Byrnes, K.R.3    Hanscom, M.4    Loane, D.J.5    Faden, A.I.6
  • 55
    • 54949085009 scopus 로고    scopus 로고
    • Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma
    • Hilton, G.D., Stoica, B.A., Byrnes, K.R., and Faden, A.I. (2008). Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma. J. Cereb. Blood Flow Metab. 28, 1845-1859
    • (2008) J. Cereb. Blood Flow Metab , vol.2 , pp. 1845-1859
    • Hilton, G.D.1    Stoica, B.A.2    Byrnes, K.R.3    Faden, A.I.4
  • 57
    • 33947603193 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3b in early depressive behavior induced by mild traumatic brain injury
    • Shapira, M., Licht, A., Milman, A., Pick, C.G., Shohami, E., and Eldar-Finkelman, H. (2007). Role of glycogen synthase kinase-3b in early depressive behavior induced by mild traumatic brain injury. Mol. Cell Neurosci. 34, 571-577
    • (2007) Mol. Cell Neurosci , vol.3 , pp. 571-577
    • Shapira, M.1    Licht, A.2    Milman, A.3    Pick, C.G.4    Shohami, E.5    Eldar-Finkelman, H.6
  • 58
    • 84882949938 scopus 로고    scopus 로고
    • Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury
    • Wu, X., Mao, H., Liu, J., Xu, J., Cao, J., Gu, X., and Cui, G. (2013). Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury. Int. J. Clin. Exp. Pathol. 6, 1282-1293
    • (2013) Int. J. Clin. Exp. Pathol , vol.6 , pp. 282-1293
    • Wu, X.1    Mao, H.2    Liu, J.3    Xu, J.4    Cao, J.5    Gu, X.6    Cui, G.7
  • 59
    • 84872551783 scopus 로고    scopus 로고
    • Abnormal hyperphosphorylation of tau: Sites, regulation, and molecular mechanism of neurofibrillary degeneration
    • Wang, J.Z., Xia, Y.Y., Grundke-Iqbal, I., and Iqbal, K. (2013). Abnormal hyperphosphorylation of tau: Sites, regulation, and molecular mechanism of neurofibrillary degeneration. J. Alzheimers Dis. 33, 123-139
    • (2013) J. Alzheimers Dis , vol.33 , pp. 123-139
    • Wang, J.Z.1    Xia, Y.Y.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 60
    • 84889596911 scopus 로고    scopus 로고
    • B-Amyloid impairs the regulation of N-methyl-D-Aspartate receptors by glycogen synthase kinase 3
    • Deng, Y., Xiong, Z., Chen, P., Wei, J., Chen, S., and Yan, Z. (2013). b-Amyloid impairs the regulation of N-methyl-D-Aspartate receptors by glycogen synthase kinase 3. Neurobiol. Aging 35, 449-459
    • (2013) Neurobiol. Aging , vol.35 , pp. 449-459
    • Deng, Y.1    Xiong, Z.2    Chen, P.3    Wei, J.4    Chen, S.5    Yan, Z.6
  • 61
    • 80052860049 scopus 로고    scopus 로고
    • Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome
    • Dash, P.K., Johnson, D., Clark, J., Orsi, S.A., Zhang, M., Zhao, J., Grill, R.J., Moore, A.N., and Pati, S. (2011). Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome. PLoS One 6, e24648
    • (2011) PLoS One , vol.6
    • Dash, P.K.1    Johnson, D.2    Clark, J.3    Orsi, S.A.4    Zhang, M.5    Zhao, J.6    Grill, R.J.7    Moore, A.N.8    Pati, S.9
  • 62
    • 84876332855 scopus 로고    scopus 로고
    • Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3b inhibition in a mouse model of intracerebral hemorrhage
    • Wang, T., Huang, Y., Zhang, M., Wang, L., Wang, Y., Zhang, L., Dong, W., Chang, P., Wang, Z., Chen, X., and Tao, L. (2013). [Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3b inhibition in a mouse model of intracerebral hemorrhage. Behav. Brain Res. 247, 132-139
    • (2013) Behav. Brain Res , vol.24 , pp. 132-139
    • Wang, T.1    Huang, Y.2    Zhang, M.3    Wang, L.4    Wang, Y.5    Zhang, L.6    Dong, W.7    Chang, P.8    Wang, Z.9    Chen, X.10    Tao, L.11
  • 64
    • 0042235278 scopus 로고    scopus 로고
    • Isoform-specific induction of PKC-e by high glucose protects heart-derived H9-2 cells against hypoxic injury
    • Kim, M.H., Jung, Y., Moon, C., Jeong, E., Lee, S.H., Baik, E.J., and Moon, C. (2003). Isoform-specific induction of PKC-e by high glucose protects heart-derived H9-2 cells against hypoxic injury. Biochem. Biophys. Res. Commun. 309, 1-6
    • (2003) Biochem. Biophys. Res. Commun , vol.3 , pp. 1-6
    • Kim, M.H.1    Jung, Y.2    Moon, C.3    Jeong, E.4    Lee, S.H.5    Baik, E.J.6    Moon, C.7
  • 65
    • 0032540311 scopus 로고    scopus 로고
    • Developmental regulation and PKC dependence of Alzheimer's-Type tau phosphorylations in cultured fetal rat hippocampal neurons
    • Combs, C.K., Coleman, P.D., and O'Banion, M.K. (1998). Developmental regulation and PKC dependence of Alzheimer's-Type tau phosphorylations in cultured fetal rat hippocampal neurons. Dev. Brain Res. 107, 143-158
    • (1998) Dev. Brain Res , vol.1 , pp. 143-158
    • Combs, C.K.1    Coleman, P.D.2    O'Banion, M.K.3
  • 67
    • 79958795394 scopus 로고    scopus 로고
    • Fronteir of epilepsy research-mTOR signaling pathway
    • Cho, C. (2011). Fronteir of epilepsy research-mTOR signaling pathway. Exp. Mol. Med. 43, 231-274
    • (2011) Exp. Mol. Med , vol.43 , pp. 231-274
    • Cho, C.1
  • 69
    • 71749114441 scopus 로고    scopus 로고
    • Formal total synthesis of (-) -balanol: A potent PKC inhibitor
    • Yaragorla, S., and Muthyala, R. (2010). Formal total synthesis of (-) -balanol: A potent PKC inhibitor. Tetrahedron Lett. 51, 467-470
    • (2010) Tetrahedron Lett , vol.51 , pp. 467-470
    • Yaragorla, S.1    Muthyala, R.2
  • 70
    • 84856065447 scopus 로고    scopus 로고
    • Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice
    • Tran, H.T., Sanchez, L., and Brody, D.L. (2012). Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice. J. Neuropathol. Exp. Neurol. 71, 116-129
    • (2012) J. Neuropathol. Exp. Neurol , vol.71 , pp. 116-129
    • Tran, H.T.1    Sanchez, L.2    Brody, D.L.3
  • 71
    • 0036197012 scopus 로고    scopus 로고
    • Differential activation of mitogen-Activated protein kinase pathways after traumatic brain injury in the rat hippocampus
    • Otani, N., Nawashiro, H., Fukui, S., Nomura, N., Yano, A., Miyazawa, T., and Shima, K. (2002). Differential activation of mitogen-Activated protein kinase pathways after traumatic brain injury in the rat hippocampus. J. Cereb. Blood Flow Metab. 22, 327-334
    • (2002) J. Cereb. Blood Flow Metab , vol.2 , pp. 327-334
    • Otani, N.1    Nawashiro, H.2    Fukui, S.3    Nomura, N.4    Yano, A.5    Miyazawa, T.6    Shima, K.7
  • 72
    • 84872121260 scopus 로고    scopus 로고
    • Effect of c-Jun NH2-Terminal kinase-mediated p53 expression on neuron autophagy following traumatic brain injury in rats
    • Hong, M.Y., Gao, J.L., Cui, J.Z., Wang, K.J., Tian, Y.X., Li, R., Wang, H.T., and Wang, H. (2012). Effect of c-Jun NH2-Terminal kinase-mediated p53 expression on neuron autophagy following traumatic brain injury in rats. Chin. Med. J. 125, 2019-2024
    • (2012) Chin. Med. J. , vol.125 , pp. 2019-2024
    • Hong, M.Y.1    Gao, J.L.2    Cui, J.Z.3    Wang, K.J.4    Tian, Y.X.5    Li, R.6    Wang, H.T.7    Wang, H.8
  • 73
    • 84864095849 scopus 로고    scopus 로고
    • Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of erk and jnk mapk
    • Armstead, W.M., Riley, J., Cines, D.B., and Higazi, A.A. (2012). Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation During hypotension after traumatic brain injury through inhibition of ERK and JNK MAPK. Neurol. Res. 34, 530-537
    • (2012) Neurol. Res , vol.34 , pp. 530-537
    • Armstead, W.M.1    Riley, J.2    Cines, D.B.3    Higazi, A.A.4
  • 74
    • 79952765069 scopus 로고    scopus 로고
    • Tpa contributes to impaired nmda cerebrovasodilation after traumatic brain injury through activation of jnkmapk
    • Armstead, W.M., Kiessling, J.W., Riley, J., Cines, D.B., and Higazi, A.A. (2011). tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNKMAPK. Neurol. Res. 33, 726-733
    • (2011) Neurol. Res , vol.33 , pp. 726-733
    • Armstead, W.M.1    Kiessling, J.W.2    Riley, J.3    Cines, D.B.4    Higazi, A.A.5
  • 75
    • 0242409714 scopus 로고    scopus 로고
    • Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro
    • Ksiezak-Reding, H., Pyo, H.K., Feinstein, B., and Pasinetti, G.M. (2003). Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro. Biochim. Biophys. Acta 1639, 159-168
    • (2003) Biochim. Biophys. Acta , vol.1639 , pp. 159-168
    • Ksiezak-Reding, H.1    Pyo, H.K.2    Feinstein, B.3    Pasinetti, G.M.4
  • 77
    • 84873194154 scopus 로고    scopus 로고
    • Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of pten and akt pathway: Scriptaid protects against tbi via akt
    • Wang, G., Jiang, X., Pu, H., Zhang, W., An, C., Hu, X., Liou, A.K., Leak, R.K., Gao, Y., and Chen, J. (2013). Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway: Scriptaid protects against TBI via AKT. Neurotherapeutics 10, 124-142
    • (2013) Neurotherapeutics , vol.10 , pp. 124-142
    • Wang, G.1    Jiang, X.2    Pu, H.3    Zhang, W.4    An, C.5    Hu, X.6    Liou, A.K.7    Leak, R.K.8    Gao, Y.9    Chen, J.10
  • 78
    • 84881106542 scopus 로고    scopus 로고
    • Structure, regulation, and pharmacological modulation of PP2A phosphatases
    • Lambrecht, C., Haesen, D., Sents, W., Ivanova, E., and Janssens, V. (2013). Structure, regulation, and pharmacological modulation of PP2A phosphatases. Methods Mol. Biol. 1053, 283-305
    • (2013) Methods Mol. Biol , vol.10 , pp. 283-305
    • Lambrecht, C.1    Haesen, D.2    Sents, W.3    Ivanova, E.4    Janssens, V.5
  • 80
    • 76349104216 scopus 로고    scopus 로고
    • Expression of protein phosphatase 2B (calcineurin) subunit A isoforms in rat hippocampus after traumatic brain injury
    • Bales, J.W., Ma, X., Yan, H.Q., Jenkins, L.W., and Dixon, C.E. (2010). Expression of protein phosphatase 2B (calcineurin) subunit A isoforms in rat hippocampus after traumatic brain injury. J. Neurotrauma 27, 109-120
    • (2010) J. Neurotrauma , vol.27 , pp. 109-120
    • Bales, J.W.1    Ma, X.2    Yan, H.Q.3    Jenkins, L.W.4    Dixon, C.E.5
  • 83
    • 79952102509 scopus 로고    scopus 로고
    • Does IGF-1 administration after a mild traumatic brain injury in mice activate the adaptive arm of ER stress?
    • Rubovitch, V., Shachar, A., Werner, H., and Pick, C.G. (2011). Does IGF-1 administration after a mild traumatic brain injury in mice activate the adaptive arm of ER stress?. Neurochem. Int. 58, 443-446
    • (2011) Neurochem. Int , vol.58 , pp. 443-446
    • Rubovitch, V.1    Shachar, A.2    Werner, H.3    Pick, C.G.4
  • 84
    • 63149183734 scopus 로고    scopus 로고
    • Apolipoprotein E-deficient mice are more vulnerable to ER stress after transient forebrain ischemia
    • Osada, N., Kosuge, Y., Kihara, T., Ishige, K., and Ito, Y. (2009). Apolipoprotein E-deficient mice are more vulnerable to ER stress after transient forebrain ischemia. Neurochem. Int. 54, 403-409
    • (2009) Neurochem. Int , vol.5 , pp. 403-409
    • Osada, N.1    Kosuge, Y.2    Kihara, T.3    Ishige, K.4    Ito, Y.5
  • 85
    • 29244462498 scopus 로고    scopus 로고
    • Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
    • Cullinan, S.B., and Diehl, J.A. (2006). Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway. Int. J. Biochem. Cell Biol. 38, 317-332
    • (2006) Int. J. Biochem. Cell Biol , vol.3 , pp. 317-332
    • Cullinan, S.B.1    Diehl, J.A.2
  • 86
    • 84855297886 scopus 로고    scopus 로고
    • 3-Bromo-7-nitroindazole attenuates brain ischemic injury in Diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP
    • Srinivasan, K., and Sharma, S.S. (2012). 3-Bromo-7-nitroindazole attenuates brain ischemic injury in Diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP. Life Sci. 90, 154-160
    • (2012) Life Sci , vol.90 , pp. 154-160
    • Srinivasan, K.1    Sharma, S.S.2
  • 88
    • 78651364538 scopus 로고    scopus 로고
    • Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury
    • Krajewska, M., Xu, L., Xu, W., Krajewski, S., Kress, C.L., Cui, J., Yang, L., Irie, F., Yamaguchi, Y., Lipton, S.A., and Reed, J.C. (2011). Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res. 1370, 227-237
    • (2011) Brain Res , vol.13 , pp. 227-237
    • Krajewska, M.1    Xu, L.2    Xu, W.3    Krajewski, S.4    Kress, C.L.5    Cui, J.6    Yang, L.7    Irie, F.8    Yamaguchi, Y.9    Lipton, S.A.10    Reed, J.C.11
  • 89
    • 84867885631 scopus 로고    scopus 로고
    • Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death
    • Gong, T., Wang, Q., Lin, Z., Chen, M., and Sun, G. (2012). Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death. Biochem. Biophys. Res. Commun. 427, 461-465
    • (2012) Biochem. Biophys. Res. Commun , vol.42 , pp. 461-465
    • Gong, T.1    Wang, Q.2    Lin, Z.3    Chen, M.4    Sun, G.5
  • 90
    • 84890552198 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments
    • King, M.K., Pardo, M., Cheng, Y., Downey, K., Jope, R.S., and Beurel, E. (2014). Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments. Pharmacol. Ther. 141, 1-12
    • (2014) Pharmacol. Ther , vol.14 , pp. 1-12
    • King, M.K.1    Pardo, M.2    Cheng, Y.3    Downey, K.4    Jope, R.S.5    Beurel, E.6
  • 91
    • 84878209604 scopus 로고    scopus 로고
    • A Rehabilomics focused perspective on molecular mechanisms underlying neurological injury, complications, and recovery after severe TBI
    • Wagner, A.K., and Zitelli, K.T. (2013). A Rehabilomics focused perspective on molecular mechanisms underlying neurological injury, complications, and recovery after severe TBI. Pathophysiology 20, 39-48
    • (2013) Pathophysiology , vol.20 , pp. 39-48
    • Wagner, A.K.1    Zitelli, K.T.2
  • 92
    • 33751346802 scopus 로고    scopus 로고
    • Activation of calcium/calmodulin-dependent protein kinases after traumatic brain injury
    • Atkins, C.M., Chen, S., Alonso, O.F., Dietrich, W.D., and Hu, B.R. (2006). Activation of calcium/calmodulin-dependent protein kinases after traumatic brain injury. J. Cereb. Blood Flow Metab. 26, 1507-1518
    • (2006) J. Cereb. Blood Flow Metab , vol.2 , pp. 1507-1518
    • Atkins, C.M.1    Chen, S.2    Alonso, O.F.3    Dietrich, W.D.4    Hu, B.R.5
  • 94
    • 84878519876 scopus 로고    scopus 로고
    • Inhibitory effects of p38 inhibitor against mitochondrial dysfunction in the early brain injury after subarachnoid hemorrhage in mice
    • Huang, L., Wan, J., Chen, Y., Wang, Z., Hui, L., Li, Y., Xu, D., and Zhou, W. (2013). Inhibitory effects of p38 inhibitor against mitochondrial dysfunction in the early brain injury after subarachnoid hemorrhage in mice. Brain Res. 1517, 133-140
    • (2013) Brain Res , vol.15 , pp. 133-140
    • Huang, L.1    Wan, J.2    Chen, Y.3    Wang, Z.4    Hui, L.5    Li, Y.6    Xu, D.7    Zhou, W.8
  • 95
    • 39049127161 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-Aminoimidazole-4-carboxamide riboside is independent of AMP-Activated protein kinase
    • Kuo, C.L., Ho, F.M., Chang, M.Y., Prakash, E., and Lin, W.W. (2008). Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-Aminoimidazole-4-carboxamide riboside is independent of AMP-Activated protein kinase. J. Cell Biochem. 103, 931-940
    • (2008) J. Cell Biochem , vol.1 , pp. 931-940
    • Kuo, C.L.1    Ho, F.M.2    Chang, M.Y.3    Prakash, E.4    Lin, W.W.5
  • 96
    • 77950930693 scopus 로고    scopus 로고
    • Microglia signaling as a target of donepezil
    • Hwang, J., Hwang, H., Lee, H., and Suk, K. (2010). Microglia signaling as a target of donepezil. Neuropharmacology 58, 1122-1129
    • (2010) Neuropharmacology , vol.58 , pp. 1122-1129
    • Hwang, J.1    Hwang, H.2    Lee, H.3    Suk, K.4
  • 99
    • 79951567558 scopus 로고    scopus 로고
    • The National Football League and concussion: Leading a culture change in contact sports
    • Ellenbogen, R.G., Berger, M.S., and Batjer, H.H. (2010). The National Football League and concussion: Leading a culture change in contact sports. World Neurosurg. 74, 560-565
    • (2010) World Neurosurg , vol.74 , pp. 560-565
    • Ellenbogen, R.G.1    Berger, M.S.2    Batjer, H.H.3


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