Novel ortho ester-based, pH-sensitive cationic lipid for gene delivery in vitro and in vivo

Journal of Liposome Research

Volumn 24, Issue 2, 2014, Pages 90-98

  Guo, Xin ^a,b   Gagne, Lucie ^b   Chen, Haigang ^a   Szoka, Francis C ^b  

^a UNIVERSITY OF THE PACIFIC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acid labile; cationic liposome; endosome; intratracheal; lipoplex

Indexed keywords

LIPOPLEX; LUCIFERASE; PLASMID DNA; POLY(ORTHO ESTER); TERTIARY AMINE; 1,2-DIOLEOYL-GLYCERO-3-PHOSPHATIDYL ETHANOLAMINE; CATION; CHOLESTEROL; DNA; ETHANOLAMINE DERIVATIVE; LIPOSOME; N,N-DIMETHYL-(4-METHOXY-(CHOLEST-5-EN-3-OXY)HEPT-3,5-DIOXA-YL)AMINE; PHOSPHATIDYLETHANOLAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL CULTURE; CONTROLLED STUDY; DRUG FORMULATION; DRUG HYDROLYSIS; FEMALE; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL DELIVERY; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SURFACE CHARGE; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CHEMISTRY; GENETIC TRANSFECTION; PROCEDURES; SYNTHESIS; TRACHEA;

ANIMALS; CATIONS; CELL LINE; CHOLESTEROL; DNA; ETHANOLAMINES; FEMALE; HYDROGEN-ION CONCENTRATION; IN VITRO TECHNIQUES; LIPOSOMES; MICE; PHOSPHATIDYLETHANOLAMINES; TRACHEA; TRANSFECTION;

EID: 84903796217     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.3109/08982104.2013.848886     Document Type: Review

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