Fliposomes: pH-controlled release from liposomes containing new trans-2-morpholinocyclohexanol-based amphiphiles that perform a conformational flip and trigger an instant cargo release upon acidification

Natural Product Communications

Volumn 7, Issue 3, 2012, Pages 353-358

  Zheng, Yu ^a   Liu, Xin ^a   Samoshina, Nataliya M ^a   Chertkov, Vyacheslav A ^b   Franz, Andreas H ^a   Guo, Xin ^a   Samoshin, Vyacheslav V ^a  

^a UNIVERSITY OF THE PACIFIC   (United States)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Acid triggered leakage; Conformational switch; Controlled release; Fliposomes; pH sensitive liposomes

Indexed keywords

1,4 XYLENE BISPYRIDINIUM; 2 MORPHOLINOCYCLOHEXANOL; AMINONAPHTHALENE 1,3,6 TRISULFONIC ACID; AMPHOPHILE; CERAMIDE; FLIPOSOME; HEXANOL; LIPID; LIPOSOME; PYRIDINIUM DERIVATIVE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG RELEASE; LIPOSOME MEMBRANE; MEMBRANE; MOLECULAR SIZE; MOLECULAR STABILITY; PH; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE; TITRIMETRY;

EID: 84860745591     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1200700317     Document Type: Article

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