Developmental programming by high fructose decreases phosphorylation efficiency in aging offspring brain mitochondria, correlating with enhanced UCP5 expression

Journal of Cerebral Blood Flow and Metabolism

Volumn 34, Issue 7, 2014, Pages 1205-1211

  Mortensen, Ole H ^a   Larsen, Lea H ^a   Ørstrup, Laura K H ^a   Hansen, Lillian H L ^a   Grunnet, Niels ^a   Quistorff, Bjørn ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

aging; brain development; energy metabolism; gene regulation; mitochondria

Indexed keywords

FRUCTOSE; MALIC ACID; MESSENGER RNA; PYRUVIC ACID; ROTENONE; SUCCINIC ACID; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 5;

AGING; ANIMAL EXPERIMENT; ARTICLE; BIRTH WEIGHT; BODY FAT; BRAIN DEVELOPMENT; BRAIN FUNCTION; BRAIN MITOCHONDRION; CONTROLLED STUDY; FEMALE; FISCHER 344 RAT; LACTATION; LITTER SIZE; MALE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; WEANING;

ANIMALS; BLOTTING, WESTERN; BRAIN; CELL RESPIRATION; DIET; FEMALE; FRUCTOSE; MALE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84903794567     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.72     Document Type: Article

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