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Volumn 85, Issue 9, 2007, Pages 2017-2025

Neuroprotective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) in MPP+-induced alteration of translational control in neuro-2a neuroblastoma cells

Author keywords

MPP+, translational control; Neuroblastoma cells; Neuroprotection; PACAP; VIP

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 4',6 DIAMIDINO 2 PHENYLINDOLE; CASPASE 3; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE R; S6 KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELF 2ALPHA; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 34447337779     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21318     Document Type: Article
Times cited : (39)

References (58)
  • 3
    • 0031678491 scopus 로고    scopus 로고
    • Perspectives on pituitary adenylate cyclase-activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous system
    • Arimura A. 1998. Perspectives on pituitary adenylate cyclase-activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous system. Jpn J Physiol 48:301-331.
    • (1998) Jpn J Physiol , vol.48 , pp. 301-331
    • Arimura, A.1
  • 4
    • 9644303217 scopus 로고    scopus 로고
    • Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease
    • Bando Y, Onuki R, Katayama T, Manabe T, Kudo T, Taira K, Tohyama M. 2005. Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease. Neurochem Int 46:11-18.
    • (2005) Neurochem Int , vol.46 , pp. 11-18
    • Bando, Y.1    Onuki, R.2    Katayama, T.3    Manabe, T.4    Kudo, T.5    Taira, K.6    Tohyama, M.7
  • 5
    • 0014368173 scopus 로고
    • Dopamine and dopamine metabolites in Parkinson's disease -a review
    • Barbeau A. 1968. Dopamine and dopamine metabolites in Parkinson's disease -a review. Proc Aust Assoc Neurol 5:95-100.
    • (1968) Proc Aust Assoc Neurol , vol.5 , pp. 95-100
    • Barbeau, A.1
  • 8
    • 0036892618 scopus 로고    scopus 로고
    • Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2-alpha in neuronal degeneration
    • Chang RCC, Suen KC, Ma CH, Elyaman W, Ng H, Hugon J. 2002a. Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2-alpha in neuronal degeneration. J Neurochem 83:1215-1225.
    • (2002) J Neurochem , vol.83 , pp. 1215-1225
    • Chang, R.C.C.1    Suen, K.C.2    Ma, C.H.3    Elyaman, W.4    Ng, H.5    Hugon, J.6
  • 9
    • 0037147666 scopus 로고    scopus 로고
    • Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease
    • Chang RC, Wong AK, Ng HK, Hugon J. 2002b. Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease. Neuroreport 13:2429-2432.
    • (2002) Neuroreport , vol.13 , pp. 2429-2432
    • Chang, R.C.1    Wong, A.K.2    Ng, H.K.3    Hugon, J.4
  • 10
    • 0021800714 scopus 로고
    • Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes
    • Chiba K, Trevor A, Catagnoli N Jr. 1985. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes. Biochem Biophys Res Commun 128:1228-1232.
    • (1985) Biochem Biophys Res Commun , vol.128 , pp. 1228-1232
    • Chiba, K.1    Trevor, A.2    Catagnoli Jr., N.3
  • 11
    • 26444529541 scopus 로고    scopus 로고
    • Cell type specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection
    • Chung CY, Seo H, Sonntag KC, Brooks A, Lin L, Isacson O. 2005. Cell type specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection. Hum Mol Genet 14:1709-1725.
    • (2005) Hum Mol Genet , vol.14 , pp. 1709-1725
    • Chung, C.Y.1    Seo, H.2    Sonntag, K.C.3    Brooks, A.4    Lin, L.5    Isacson, O.6
  • 12
    • 0028433524 scopus 로고
    • Regulation of eukaryotic protein synthesis by protein kinases that phosphorylate initiation factor eIF-2
    • Clemens MJ. 1994. Regulation of eukaryotic protein synthesis by protein kinases that phosphorylate initiation factor eIF-2. Mol Biol Rep 19:201-210.
    • (1994) Mol Biol Rep , vol.19 , pp. 201-210
    • Clemens, M.J.1
  • 13
    • 0035527326 scopus 로고    scopus 로고
    • Translational regulation in cell stress and apoptosis. Role of the eIF4E binding proteins
    • Clemens MJ. 2001. Translational regulation in cell stress and apoptosis. Role of the eIF4E binding proteins. J Cell Mol Med 5:221-239.
    • (2001) J Cell Mol Med , vol.5 , pp. 221-239
    • Clemens, M.J.1
  • 14
    • 22744432325 scopus 로고    scopus 로고
    • Neuroprotective potential of three neuropeptides PACAP, VIP and PHI
    • Dejda A, Sokolowska P, Nowak JZ. 2005. Neuroprotective potential of three neuropeptides PACAP, VIP and PHI. Pharmacol Rep 57:307-320.
    • (2005) Pharmacol Rep , vol.57 , pp. 307-320
    • Dejda, A.1    Sokolowska, P.2    Nowak, J.Z.3
  • 15
    • 0035983277 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia
    • Delgado M, Jonakait GM, Ganea D. 2002. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia. Glia 39:148-161.
    • (2002) Glia , vol.39 , pp. 148-161
    • Delgado, M.1    Jonakait, G.M.2    Ganea, D.3
  • 16
    • 0038322494 scopus 로고    scopus 로고
    • Neuroprotective effect of vasoactive intestinal peptide (VIP) in a mouse model of Parkinson's disease by blocking microglial activation
    • Delgado M, Ganea D. 2003. Neuroprotective effect of vasoactive intestinal peptide (VIP) in a mouse model of Parkinson's disease by blocking microglial activation. FASEB J 17:944-946.
    • (2003) FASEB J , vol.17 , pp. 944-946
    • Delgado, M.1    Ganea, D.2
  • 17
    • 0026660275 scopus 로고
    • The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth
    • Deutsch PJ, Sun Y. 1992. The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth. J Biol Chem 267:5108-5113.
    • (1992) J Biol Chem , vol.267 , pp. 5108-5113
    • Deutsch, P.J.1    Sun, Y.2
  • 18
    • 0037154965 scopus 로고    scopus 로고
    • Gene-specific regulation by general translation factors
    • Dever TE. 2002. Gene-specific regulation by general translation factors. Cell 108:545-556.
    • (2002) Cell , vol.108 , pp. 545-556
    • Dever, T.E.1
  • 19
    • 0033604521 scopus 로고    scopus 로고
    • Ribosomal S6 kinase signaling and the control of translation
    • Dufner A, Thomas G. 1999 Ribosomal S6 kinase signaling and the control of translation. Exp Cell Res 253:100-109.
    • (1999) Exp Cell Res , vol.253 , pp. 100-109
    • Dufner, A.1    Thomas, G.2
  • 20
    • 0024437487 scopus 로고
    • Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation
    • Duncan RF, Hershey JW. 1989. Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation. J Cell Biol 109:1467-1481.
    • (1989) J Cell Biol , vol.109 , pp. 1467-1481
    • Duncan, R.F.1    Hershey, J.W.2
  • 21
    • 0026710878 scopus 로고
    • Glutamate-induced ribosomal disaggregation abd ultrastructural changes in rat cortical neuronal culture: Protective effect of horse serum
    • Dux E, Oschlies U, Wiessner C, Hossmann KA. 1992. Glutamate-induced ribosomal disaggregation abd ultrastructural changes in rat cortical neuronal culture: protective effect of horse serum. Neurosci Lett 141:173-176.
    • (1992) Neurosci Lett , vol.141 , pp. 173-176
    • Dux, E.1    Oschlies, U.2    Wiessner, C.3    Hossmann, K.A.4
  • 22
    • 0033104442 scopus 로고    scopus 로고
    • Characterization and time course of MPP+-induced apoptosis in human SH-SY5Y neuroblastoma cells
    • Fall CP, Bennett JP Jr. 1999. Characterization and time course of MPP+-induced apoptosis in human SH-SY5Y neuroblastoma cells. J Neurosci Res 55:620-628.
    • (1999) J Neurosci Res , vol.55 , pp. 620-628
    • Fall, C.P.1    Bennett Jr., J.P.2
  • 23
    • 0032834055 scopus 로고    scopus 로고
    • eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
    • Gingras AC, Raught B., Sonenberg N. 1999. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem 68:913-963.
    • (1999) Annu Rev Biochem , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 25
    • 0035233058 scopus 로고    scopus 로고
    • Control of translation by the target of rapamycin proteins
    • Gingras AC, Raught B, Sonenberg N. 2001b. Control of translation by the target of rapamycin proteins. Prog Mol Subcell Biol 27:143-174.
    • (2001) Prog Mol Subcell Biol , vol.27 , pp. 143-174
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 27
    • 0042575744 scopus 로고    scopus 로고
    • Mitochondria: Regulators of cell death and survival
    • Granville DJ, Gottlieb RA. 2002. Mitochondria: regulators of cell death and survival. Scientific World Journal 2:1569-1578.
    • (2002) Scientific World Journal , vol.2 , pp. 1569-1578
    • Granville, D.J.1    Gottlieb, R.A.2
  • 29
    • 0038143287 scopus 로고    scopus 로고
    • Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
    • Holtz WA, O'Malley KL. 2003. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J Biol Chem 278:19367-19377.
    • (2003) J Biol Chem , vol.278 , pp. 19367-19377
    • Holtz, W.A.1    O'Malley, K.L.2
  • 30
    • 0021353373 scopus 로고
    • Regional impairment of protein synthesis in the rat brain during bicuculline-induced seizures
    • Kiessling M, Xie Y, Kleihues P. 1984. Regional impairment of protein synthesis in the rat brain during bicuculline-induced seizures. Brain Res 296:1-13.
    • (1984) Brain Res , vol.296 , pp. 1-13
    • Kiessling, M.1    Xie, Y.2    Kleihues, P.3
  • 32
  • 33
    • 0037098967 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal peptide attenuate glutamate-induced nNOS activation and cytotoxicity
    • Onoue S, Endo K, Yajima T, Kashimoto K. 2002a. Pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal peptide attenuate glutamate-induced nNOS activation and cytotoxicity. Regul Pept 107:43-47.
    • (2002) Regul Pept , vol.107 , pp. 43-47
    • Onoue, S.1    Endo, K.2    Yajima, T.3    Kashimoto, K.4
  • 34
    • 0036701530 scopus 로고    scopus 로고
    • The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells
    • Onoue S, Endo K, Ohshima K, Yajima T, Kashimoto K. 2002b. The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells. Peptides 23:1471-1478.
    • (2002) Peptides , vol.23 , pp. 1471-1478
    • Onoue, S.1    Endo, K.2    Ohshima, K.3    Yajima, T.4    Kashimoto, K.5
  • 35
    • 27844530579 scopus 로고    scopus 로고
    • The relation between p70S6k expression in lymphocytes and the decline of cognitive test scores in patients with Alzheimer disease
    • Paccalin M, Pain Barc S, Pluchon C, Paul C, Bazin H, Gil R, Hugon J. 2005. The relation between p70S6k expression in lymphocytes and the decline of cognitive test scores in patients with Alzheimer disease. Arch Int Med 165:2428-2429.
    • (2005) Arch Int Med , vol.165 , pp. 2428-2429
    • Paccalin, M.1    Pain Barc, S.2    Pluchon, C.3    Paul, C.4    Bazin, H.5    Gil, R.6    Hugon, J.7
  • 37
    • 0036314780 scopus 로고    scopus 로고
    • Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors
    • Patel J, McLeod LE, Vries RG, Flynn A, Wang X, Proud CG. 2002. Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors. Eur J Biochem 269:3076-3085.
    • (2002) Eur J Biochem , vol.269 , pp. 3076-3085
    • Patel, J.1    McLeod, L.E.2    Vries, R.G.3    Flynn, A.4    Wang, X.5    Proud, C.G.6
  • 38
    • 0026465921 scopus 로고
    • Protein phosphorylation in translational control [review]
    • Proud CG. 1992. Protein phosphorylation in translational control [review]. Curr Top Cell Regul 32:243-369.
    • (1992) Curr Top Cell Regul , vol.32 , pp. 243-369
    • Proud, C.G.1
  • 39
    • 0029983808 scopus 로고    scopus 로고
    • Synthesis, modifications, and turnover of proteins during aging
    • Rattan SI. 1996. Synthesis, modifications, and turnover of proteins during aging. Exp Gerontol 31:33-47.
    • (1996) Exp Gerontol , vol.31 , pp. 33-47
    • Rattan, S.I.1
  • 41
    • 4444355926 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide protects dopaminergic neurons and improves behavioral deficits in a rat model of Parkinson's disease
    • Reglodi D, Lubics A, Tamas A, Szalontay L, Lengvari I. 2004a. Pituitary adenylate cyclase-activating polypeptide protects dopaminergic neurons and improves behavioral deficits in a rat model of Parkinson's disease. Behav Brain Res 151:303-312.
    • (2004) Behav Brain Res , vol.151 , pp. 303-312
    • Reglodi, D.1    Lubics, A.2    Tamas, A.3    Szalontay, L.4    Lengvari, I.5
  • 42
    • 7044227726 scopus 로고    scopus 로고
    • Morphological and functional effects of PACAP in 6-hydroxydopamine-induced lesion of the substantia nigra
    • Reglodi D, Tamas A, Lubics A, Szalontay L, Lengvari I. 2004b. Morphological and functional effects of PACAP in 6-hydroxydopamine-induced lesion of the substantia nigra. Regul Pept 123:85-94.
    • (2004) Regul Pept , vol.123 , pp. 85-94
    • Reglodi, D.1    Tamas, A.2    Lubics, A.3    Szalontay, L.4    Lengvari, I.5
  • 43
    • 0034006915 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: A pathogenetic factor in Parkinson's disease
    • Reichmann H, Janetzky B. 2000. Mitochondrial dysfunction: a pathogenetic factor in Parkinson's disease. J Neurol 247:63-68.
    • (2000) J Neurol , vol.247 , pp. 63-68
    • Reichmann, H.1    Janetzky, B.2
  • 44
    • 0037114971 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
    • Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, Greene LA. 2002. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J Neurosci 22:10690-10698.
    • (2002) J Neurosci , vol.22 , pp. 10690-10698
    • Ryu, E.J.1    Harding, H.P.2    Angelastro, J.M.3    Vitolo, O.V.4    Ron, D.5    Greene, L.A.6
  • 45
    • 0035834676 scopus 로고    scopus 로고
    • Translation inhibition in apoptosis: Caspase-dependent PKR activation and eIF2-alpha phosphorylation
    • Saelens X, Kalai M, Vandenabeele P. 2001. Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation. J Biol Chem 276:41620-41628.
    • (2001) J Biol Chem , vol.276 , pp. 41620-41628
    • Saelens, X.1    Kalai, M.2    Vandenabeele, P.3
  • 46
    • 0014954352 scopus 로고
    • Polypeptide with broad biological activity: Isolation from small intestine
    • Said SI, Mutt V. 1970. Polypeptide with broad biological activity: isolation from small intestine. Science 169:1217-1218.
    • (1970) Science , vol.169 , pp. 1217-1218
    • Said, S.I.1    Mutt, V.2
  • 47
    • 0032569681 scopus 로고    scopus 로고
    • Protective effects of vasoactive intestinal peptide against delayed glutamate neurotoxicity in cultured retina
    • Shoge K, Mishima HK, Saitoh T, Ishihara K, Tamura Y, Shiomi H, Sasa M. 1998. Protective effects of vasoactive intestinal peptide against delayed glutamate neurotoxicity in cultured retina. Brain Res 809:127-136.
    • (1998) Brain Res , vol.809 , pp. 127-136
    • Shoge, K.1    Mishima, H.K.2    Saitoh, T.3    Ishihara, K.4    Tamura, Y.5    Shiomi, H.6    Sasa, M.7
  • 48
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth [review]
    • Schmelzle T, Hall MN. 2000. TOR, a central controller of cell growth [review]. Cell 103:253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 49
    • 0021367697 scopus 로고
    • Recent physiological and pathophysiological aspects of Parkinsonian movement disorders
    • Schultz W. 1984. Recent physiological and pathophysiological aspects of Parkinsonian movement disorders. Life Sci 34:2213-2223.
    • (1984) Life Sci , vol.34 , pp. 2213-2223
    • Schultz, W.1
  • 50
    • 4444305508 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide: A potential neuroprotective peptide
    • Somogyvari-Vigh A, Reglodi D. 2004. Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide. Rev Curr Pharm Des 10:2861-2889.
    • (2004) Rev Curr Pharm Des , vol.10 , pp. 2861-2889
    • Somogyvari-Vigh, A.1    Reglodi, D.2
  • 51
    • 0348010382 scopus 로고    scopus 로고
    • Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity
    • Suen KC, Yu M, So KF, Chang RC, Hugon J. 2003. Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity. J Biol Chem 278:49819-49827.
    • (2003) J Biol Chem , vol.278 , pp. 49819-49827
    • Suen, K.C.1    Yu, M.2    So, K.F.3    Chang, R.C.4    Hugon, J.5
  • 52
    • 0032401022 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective effects of Pituitary adenylate cyclase-activating polypeptide (PACAP) on mesencephalic dopaminergic neurons
    • Takei N, Skoglosa Y, Lindholm D. 1998. Neurotrophic and neuroprotective effects of Pituitary adenylate cyclase-activating polypeptide (PACAP) on mesencephalic dopaminergic neurons. J Neurosci Res 54:698-706.
    • (1998) J Neurosci Res , vol.54 , pp. 698-706
    • Takei, N.1    Skoglosa, Y.2    Lindholm, D.3
  • 53
    • 0032562177 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway
    • Vaudry D, Gonzalez BJ, Basille M, Anouar Y, Fournier A, Vaudry H. 1998. Pituitary adenylate cyclase-activating polypeptide stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway. Neuroscience 84:801-812.
    • (1998) Neuroscience , vol.84 , pp. 801-812
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Anouar, Y.4    Fournier, A.5    Vaudry, H.6
  • 54
    • 0034048147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: From structure to functions
    • Vaudry D, Gonzalez BJ, Basille M, Yon L, Fournier A, Vaudry H. 2000a. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol Rev 52:269-324.
    • (2000) Pharmacol Rev , vol.52 , pp. 269-324
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Yon, L.4    Fournier, A.5    Vaudry, H.6
  • 55
    • 0034700111 scopus 로고    scopus 로고
    • The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32
    • Vaudry D, Gonzalez BJ, Basille M, Pamantung TF, Fontaine M, Fournier A, Vaudry H. 2000b. The neuroprotective effect of pituitary adenylate cyclase-activating polypeptide on cerebellar granule cells is mediated through inhibition of the CED3-related cysteine protease caspase-3/CPP32. Proc Natl Acad Sci U S A 97:13390-13395.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13390-13395
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Pamantung, T.F.4    Fontaine, M.5    Fournier, A.6    Vaudry, H.7
  • 57
    • 0036971940 scopus 로고    scopus 로고
    • Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration
    • Waschek JA. 2002. Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration. Dev Neurosci 24:14-23.
    • (2002) Dev Neurosci , vol.24 , pp. 14-23
    • Waschek, J.A.1
  • 58
    • 0032911488 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
    • Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ. 1999. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 154:1423-1429.
    • (1999) Am J Pathol , vol.154 , pp. 1423-1429
    • Zhang, J.1    Perry, G.2    Smith, M.A.3    Robertson, D.4    Olson, S.J.5    Graham, D.G.6    Montine, T.J.7


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