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Volumn 28, Issue 3, 2014, Pages 103-110

Humanized mouse models in transplantation research

Author keywords

[No Author keywords available]

Indexed keywords

GRAFT DYSFUNCTION; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HUMAN; HUMANIZED MOUSE MODEL; MEDICAL RESEARCH; MOUSE MODEL; MOUSE STRAIN; NONHUMAN; REVIEW; TRANSPLANTATION; ANIMAL; DISEASE MODEL; HISTOCOMPATIBILITY; IMMUNOLOGY; MOUSE; TRANSLATIONAL RESEARCH;

EID: 84903741746     PISSN: 0955470X     EISSN: 15579816     Source Type: Journal    
DOI: 10.1016/j.trre.2014.02.002     Document Type: Review
Times cited : (20)

References (81)
  • 1
    • 0023792756 scopus 로고
    • The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism
    • Malynn B.A., Blackwell T.K., Fulop G.M., et al. The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism. Cell 1988, 54:453-460.
    • (1988) Cell , vol.54 , pp. 453-460
    • Malynn, B.A.1    Blackwell, T.K.2    Fulop, G.M.3
  • 2
    • 0023026643 scopus 로고
    • Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency
    • Schuler W., Weiler I.J., Schuler A., et al. Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. Cell 1986, 46:963-972.
    • (1986) Cell , vol.46 , pp. 963-972
    • Schuler, W.1    Weiler, I.J.2    Schuler, A.3
  • 3
    • 0023753744 scopus 로고
    • The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function
    • McCune J.M., Namikawa R., Kaneshima H., Shultz L.D., Lieberman M., Weissman I.L. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 1988, 241:1632-1639.
    • (1988) Science , vol.241 , pp. 1632-1639
    • McCune, J.M.1    Namikawa, R.2    Kaneshima, H.3    Shultz, L.D.4    Lieberman, M.5    Weissman, I.L.6
  • 4
    • 0026581239 scopus 로고
    • Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
    • Lapidot T., Pflumio F., Doedens M., Murdoch B., Williams D.E., Dick J.E. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science 1992, 255:1137-1141.
    • (1992) Science , vol.255 , pp. 1137-1141
    • Lapidot, T.1    Pflumio, F.2    Doedens, M.3    Murdoch, B.4    Williams, D.E.5    Dick, J.E.6
  • 5
    • 0035879261 scopus 로고    scopus 로고
    • Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes
    • Berney T., Molano R.D., Pileggi A., et al. Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes. Transplantation 2001, 72:133-140.
    • (2001) Transplantation , vol.72 , pp. 133-140
    • Berney, T.1    Molano, R.D.2    Pileggi, A.3
  • 7
    • 0031026261 scopus 로고    scopus 로고
    • Limits of the human-PBL-SCID mice model: severe restriction of the V beta T-cell repertoire of engrafted human T cells
    • Garcia S., Dadaglio G., Gougeon M.L. Limits of the human-PBL-SCID mice model: severe restriction of the V beta T-cell repertoire of engrafted human T cells. Blood 1997, 89:329-336.
    • (1997) Blood , vol.89 , pp. 329-336
    • Garcia, S.1    Dadaglio, G.2    Gougeon, M.L.3
  • 8
    • 0031805237 scopus 로고    scopus 로고
    • SCID mouse models of human stem cell engraftment
    • Greiner D.L., Hesselton R.A., Shultz L.D. SCID mouse models of human stem cell engraftment. Stem Cells 1998, 16:166-177.
    • (1998) Stem Cells , vol.16 , pp. 166-177
    • Greiner, D.L.1    Hesselton, R.A.2    Shultz, L.D.3
  • 9
    • 0025011134 scopus 로고
    • The scid mutation in mice causes a general defect in DNA repair
    • Fulop G.M., Phillips R.A. The scid mutation in mice causes a general defect in DNA repair. Nature 1990, 347:479-482.
    • (1990) Nature , vol.347 , pp. 479-482
    • Fulop, G.M.1    Phillips, R.A.2
  • 10
    • 0028270857 scopus 로고
    • Human peripheral blood lymphocyte reconstituted severe combined immunodeficient (hu-PBL-SCID) mice. A model for human islet allograft rejection
    • Shiroki R., Poindexter N.J., Woodle E.S., Hussain M.S., Mohanakumar T., Scharp D.W. Human peripheral blood lymphocyte reconstituted severe combined immunodeficient (hu-PBL-SCID) mice. A model for human islet allograft rejection. Transplantation 1994, 57:1555-1562.
    • (1994) Transplantation , vol.57 , pp. 1555-1562
    • Shiroki, R.1    Poindexter, N.J.2    Woodle, E.S.3    Hussain, M.S.4    Mohanakumar, T.5    Scharp, D.W.6
  • 11
    • 0032429207 scopus 로고    scopus 로고
    • T cell engraftment in lymphoid tissues of human peripheral blood lymphocyte reconstituted SCID mice with or without prior activation of cells
    • Olive C., Cheung C., Falk M.C. T cell engraftment in lymphoid tissues of human peripheral blood lymphocyte reconstituted SCID mice with or without prior activation of cells. Immunol Cell Biol 1998, 76:520-525.
    • (1998) Immunol Cell Biol , vol.76 , pp. 520-525
    • Olive, C.1    Cheung, C.2    Falk, M.C.3
  • 12
    • 0031893205 scopus 로고    scopus 로고
    • Peritoneal macrophages play an important role in eliminating human cells from severe combined immunodeficient mice transplanted with human peripheral blood lymphocytes
    • Shibata S., Asano T., Noguchi A., Naito M., Ogura A., Doi K. Peritoneal macrophages play an important role in eliminating human cells from severe combined immunodeficient mice transplanted with human peripheral blood lymphocytes. Immunology 1998, 93:524-532.
    • (1998) Immunology , vol.93 , pp. 524-532
    • Shibata, S.1    Asano, T.2    Noguchi, A.3    Naito, M.4    Ogura, A.5    Doi, K.6
  • 13
    • 0030219809 scopus 로고    scopus 로고
    • Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice
    • Christianson S.W., Greiner D.L., Schweitzer I.B., et al. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol 1996, 171:186-199.
    • (1996) Cell Immunol , vol.171 , pp. 186-199
    • Christianson, S.W.1    Greiner, D.L.2    Schweitzer, I.B.3
  • 14
    • 0027524017 scopus 로고
    • Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation
    • Mosier D.E., Stell K.L., Gulizia R.J., Torbett B.E., Gilmore G.L. Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation. J Exp Med 1993, 177:191-194.
    • (1993) J Exp Med , vol.177 , pp. 191-194
    • Mosier, D.E.1    Stell, K.L.2    Gulizia, R.J.3    Torbett, B.E.4    Gilmore, G.L.5
  • 15
    • 0028869986 scopus 로고
    • Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice
    • Shultz L.D., Schweitzer P.A., Christianson S.W., et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol 1995, 154:180-191.
    • (1995) J Immunol , vol.154 , pp. 180-191
    • Shultz, L.D.1    Schweitzer, P.A.2    Christianson, S.W.3
  • 16
    • 0028927281 scopus 로고
    • Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice
    • Greiner D.L., Shultz L.D., Yates J., et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol 1995, 146:888-902.
    • (1995) Am J Pathol , vol.146 , pp. 888-902
    • Greiner, D.L.1    Shultz, L.D.2    Yates, J.3
  • 17
    • 0026554156 scopus 로고
    • The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency
    • Prochazka M., Gaskins H.R., Shultz L.D., Leiter E.H. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc Natl Acad Sci U S A 1992, 89:3290-3294.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3290-3294
    • Prochazka, M.1    Gaskins, H.R.2    Shultz, L.D.3    Leiter, E.H.4
  • 18
    • 0031569609 scopus 로고    scopus 로고
    • Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice
    • Christianson S.W., Greiner D.L., Hesselton R.A., et al. Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice. J Immunol 1997, 158:3578-3586.
    • (1997) J Immunol , vol.158 , pp. 3578-3586
    • Christianson, S.W.1    Greiner, D.L.2    Hesselton, R.A.3
  • 20
    • 0029591868 scopus 로고
    • Engraftment and humoral immunity in SCID and RAG-2-deficient mice transplanted with human peripheral blood lymphocytes
    • Steinsvik T.E., Gaarder P.I., Aaberge I.S., Lovik M. Engraftment and humoral immunity in SCID and RAG-2-deficient mice transplanted with human peripheral blood lymphocytes. Scand J Immunol 1995, 42:607-616.
    • (1995) Scand J Immunol , vol.42 , pp. 607-616
    • Steinsvik, T.E.1    Gaarder, P.I.2    Aaberge, I.S.3    Lovik, M.4
  • 21
    • 0027932794 scopus 로고
    • Engraftment of human lymphocytes and thyroid tissue into scid and rag2-deficient mice: absent progression of lymphocytic infiltration
    • Martin A., Valentine M., Unger P., Yeung S.W., Shultz L.D., Davies T.F. Engraftment of human lymphocytes and thyroid tissue into scid and rag2-deficient mice: absent progression of lymphocytic infiltration. J Clin Endocrinol Metab 1994, 79:716-723.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 716-723
    • Martin, A.1    Valentine, M.2    Unger, P.3    Yeung, S.W.4    Shultz, L.D.5    Davies, T.F.6
  • 22
    • 0034144688 scopus 로고    scopus 로고
    • NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells
    • Shultz L.D., Lang P.A., Christianson S.W., et al. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol 2000, 164:2496-2507.
    • (2000) J Immunol , vol.164 , pp. 2496-2507
    • Shultz, L.D.1    Lang, P.A.2    Christianson, S.W.3
  • 23
    • 23744474685 scopus 로고    scopus 로고
    • Development of functional human blood and immune systems in NOD/SCID/IL2 receptor gamma chain(null) mice
    • Ishikawa F., Yasukawa M., Lyons B., et al. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor gamma chain(null) mice. Blood 2005, 106:1565-1573.
    • (2005) Blood , vol.106 , pp. 1565-1573
    • Ishikawa, F.1    Yasukawa, M.2    Lyons, B.3
  • 24
    • 0028925778 scopus 로고
    • Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain
    • Cao X., Shores E.W., Hu-Li J., et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity 1995, 2:223-238.
    • (1995) Immunity , vol.2 , pp. 223-238
    • Cao, X.1    Shores, E.W.2    Hu-Li, J.3
  • 25
    • 20844434966 scopus 로고    scopus 로고
    • Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells
    • Shultz L.D., Lyons B.L., Burzenski L.M., et al. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 2005, 174:6477-6489.
    • (2005) J Immunol , vol.174 , pp. 6477-6489
    • Shultz, L.D.1    Lyons, B.L.2    Burzenski, L.M.3
  • 26
    • 77955477782 scopus 로고    scopus 로고
    • Comparison of human cord blood engraftment between immunocompromised mouse strains
    • McDermott S.P., Eppert K., Lechman E.R., Doedens M., Dick J.E. Comparison of human cord blood engraftment between immunocompromised mouse strains. Blood 2010, 116:193-200.
    • (2010) Blood , vol.116 , pp. 193-200
    • McDermott, S.P.1    Eppert, K.2    Lechman, E.R.3    Doedens, M.4    Dick, J.E.5
  • 27
    • 79955420739 scopus 로고    scopus 로고
    • Immunodeficient NOD-scid IL-2Rgamma(null) mice do not display T and B cell leakiness
    • Katano I., Ito R., Eto T., Aiso S., Ito M. Immunodeficient NOD-scid IL-2Rgamma(null) mice do not display T and B cell leakiness. Exp Anim 2011, 60:181-186.
    • (2011) Exp Anim , vol.60 , pp. 181-186
    • Katano, I.1    Ito, R.2    Eto, T.3    Aiso, S.4    Ito, M.5
  • 28
    • 53349118367 scopus 로고    scopus 로고
    • Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment
    • Pearson T., Shultz L.D., Miller D., et al. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment. Clin Exp Immunol 2008, 154:270-284.
    • (2008) Clin Exp Immunol , vol.154 , pp. 270-284
    • Pearson, T.1    Shultz, L.D.2    Miller, D.3
  • 29
    • 0037089413 scopus 로고    scopus 로고
    • Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo
    • Weijer K., Uittenbogaart C.H., Voordouw A., et al. Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo. Blood 2002, 99:2752-2759.
    • (2002) Blood , vol.99 , pp. 2752-2759
    • Weijer, K.1    Uittenbogaart, C.H.2    Voordouw, A.3
  • 30
    • 84880006743 scopus 로고    scopus 로고
    • Delayed onset of graft-versus-host disease in immunodeficent human leucocyte antigen-DQ8 transgenic, murine major histocompatibility complex class II-deficient mice repopulated by human peripheral blood mononuclear cells
    • Buchner S.M., Sliva K., Bonig H., et al. Delayed onset of graft-versus-host disease in immunodeficent human leucocyte antigen-DQ8 transgenic, murine major histocompatibility complex class II-deficient mice repopulated by human peripheral blood mononuclear cells. Clin Exp Immunol 2013, 173:355-364.
    • (2013) Clin Exp Immunol , vol.173 , pp. 355-364
    • Buchner, S.M.1    Sliva, K.2    Bonig, H.3
  • 31
    • 84859201276 scopus 로고    scopus 로고
    • Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/gammacnull mouse
    • Suzuki M., Takahashi T., Katano I., et al. Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/gammacnull mouse. Int Immunol 2012, 24:243-252.
    • (2012) Int Immunol , vol.24 , pp. 243-252
    • Suzuki, M.1    Takahashi, T.2    Katano, I.3
  • 32
    • 33846630040 scopus 로고    scopus 로고
    • Humanized mice in translational biomedical research
    • Shultz L.D., Ishikawa F., Greiner D.L. Humanized mice in translational biomedical research. Nat Rev Immunol 2007, 7:118-130.
    • (2007) Nat Rev Immunol , vol.7 , pp. 118-130
    • Shultz, L.D.1    Ishikawa, F.2    Greiner, D.L.3
  • 33
    • 84867898654 scopus 로고    scopus 로고
    • Humanized mice for immune system investigation: progress, promise and challenges
    • Shultz L.D., Brehm M.A., Garcia-Martinez J.V., Greiner D.L. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol 2012, 12:786-798.
    • (2012) Nat Rev Immunol , vol.12 , pp. 786-798
    • Shultz, L.D.1    Brehm, M.A.2    Garcia-Martinez, J.V.3    Greiner, D.L.4
  • 34
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • Mosier D.E., Gulizia R.J., Baird S.M., Wilson D.B. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 1988, 335:256-259.
    • (1988) Nature , vol.335 , pp. 256-259
    • Mosier, D.E.1    Gulizia, R.J.2    Baird, S.M.3    Wilson, D.B.4
  • 35
    • 1842588698 scopus 로고    scopus 로고
    • Development of a human adaptive immune system in cord blood cell-transplanted mice
    • Traggiai E., Chicha L., Mazzucchelli L., et al. Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 2004, 304:104-107.
    • (2004) Science , vol.304 , pp. 104-107
    • Traggiai, E.1    Chicha, L.2    Mazzucchelli, L.3
  • 36
    • 70349314352 scopus 로고    scopus 로고
    • Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice
    • Lepus C.M., Gibson T.F., Gerber S.A., et al. Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice. Hum Immunol 2009, 70:790-802.
    • (2009) Hum Immunol , vol.70 , pp. 790-802
    • Lepus, C.M.1    Gibson, T.F.2    Gerber, S.A.3
  • 37
    • 84879694584 scopus 로고    scopus 로고
    • Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation
    • Suzuki N., Yamazaki S., Yamaguchi T., et al. Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. Mol Ther 2013, 21:1424-1431.
    • (2013) Mol Ther , vol.21 , pp. 1424-1431
    • Suzuki, N.1    Yamazaki, S.2    Yamaguchi, T.3
  • 38
  • 39
    • 77649232760 scopus 로고    scopus 로고
    • Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation
    • Brehm M.A., Cuthbert A., Yang C., et al. Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. Clin Immunol 2010, 135:84-98.
    • (2010) Clin Immunol , vol.135 , pp. 84-98
    • Brehm, M.A.1    Cuthbert, A.2    Yang, C.3
  • 40
    • 0141481990 scopus 로고    scopus 로고
    • A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice
    • van Rijn R.S., Simonetti E.R., Hagenbeek A., et al. A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice. Blood 2003, 102:2522-2531.
    • (2003) Blood , vol.102 , pp. 2522-2531
    • van Rijn, R.S.1    Simonetti, E.R.2    Hagenbeek, A.3
  • 41
    • 33747177351 scopus 로고    scopus 로고
    • Key factors in experimental mouse hematopoietic stem cell transplantation
    • Nevozhay D., Opolski A. Key factors in experimental mouse hematopoietic stem cell transplantation. Arch Immunol Ther Exp (Warsz) 2006, 54:253-269.
    • (2006) Arch Immunol Ther Exp (Warsz) , vol.54 , pp. 253-269
    • Nevozhay, D.1    Opolski, A.2
  • 42
    • 79956121863 scopus 로고    scopus 로고
    • Mouse models of graft-versus-host disease: advances and limitations
    • Schroeder M.A., DiPersio J.F. Mouse models of graft-versus-host disease: advances and limitations. Dis Model Mech 2011, 4:318-333.
    • (2011) Dis Model Mech , vol.4 , pp. 318-333
    • Schroeder, M.A.1    DiPersio, J.F.2
  • 43
    • 67649580473 scopus 로고    scopus 로고
    • Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
    • Ito R., Katano I., Kawai K., et al. Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice. Transplantation 2009, 87:1654-1658.
    • (2009) Transplantation , vol.87 , pp. 1654-1658
    • Ito, R.1    Katano, I.2    Kawai, K.3
  • 44
    • 36148965120 scopus 로고    scopus 로고
    • Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice
    • Nervi B., Rettig M.P., Ritchey J.K., et al. Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice. Exp Hematol 2007, 35:1823-1838.
    • (2007) Exp Hematol , vol.35 , pp. 1823-1838
    • Nervi, B.1    Rettig, M.P.2    Ritchey, J.K.3
  • 45
    • 66849091880 scopus 로고    scopus 로고
    • Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex
    • King M.A., Covassin L., Brehm M.A., et al. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol 2009, 157:104-118.
    • (2009) Clin Exp Immunol , vol.157 , pp. 104-118
    • King, M.A.1    Covassin, L.2    Brehm, M.A.3
  • 46
    • 84871920365 scopus 로고    scopus 로고
    • Prevention of acute graft-versus-host disease in a xenogeneic SCID mouse model by the humanized anti-CD74 antagonistic antibody milatuzumab
    • Chen X., Chang C.H., Stein R., Cardillo T.M., Gold D.V., Goldenberg D.M. Prevention of acute graft-versus-host disease in a xenogeneic SCID mouse model by the humanized anti-CD74 antagonistic antibody milatuzumab. Biol Blood Marrow Transplant 2013, 19:28-39.
    • (2013) Biol Blood Marrow Transplant , vol.19 , pp. 28-39
    • Chen, X.1    Chang, C.H.2    Stein, R.3    Cardillo, T.M.4    Gold, D.V.5    Goldenberg, D.M.6
  • 47
    • 33746215041 scopus 로고    scopus 로고
    • Effect of macrophage migration inhibitory factor (MIF) on acute graft-versus-host disease in a murine model of allogeneic stem cell transplantation
    • Toubai T., Tanaka J., Nishihira J., et al. Effect of macrophage migration inhibitory factor (MIF) on acute graft-versus-host disease in a murine model of allogeneic stem cell transplantation. Transpl Immunol 2006, 16:117-124.
    • (2006) Transpl Immunol , vol.16 , pp. 117-124
    • Toubai, T.1    Tanaka, J.2    Nishihira, J.3
  • 48
    • 0030472390 scopus 로고    scopus 로고
    • Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease
    • Krenger W., Cooke K.R., Crawford J.M., et al. Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease. Transplantation 1996, 62:1278-1285.
    • (1996) Transplantation , vol.62 , pp. 1278-1285
    • Krenger, W.1    Cooke, K.R.2    Crawford, J.M.3
  • 49
    • 80052314685 scopus 로고    scopus 로고
    • Engraftment of peripheral blood mononuclear cells from systemic lupus erythematosus and antiphospholipid syndrome patient donors into BALB-RAG-2-/- IL-2Rgamma-/- mice: a promising model for studying human disease
    • Andrade D., Redecha P.B., Vukelic M., et al. Engraftment of peripheral blood mononuclear cells from systemic lupus erythematosus and antiphospholipid syndrome patient donors into BALB-RAG-2-/- IL-2Rgamma-/- mice: a promising model for studying human disease. Arthritis Rheum 2011, 63:2764-2773.
    • (2011) Arthritis Rheum , vol.63 , pp. 2764-2773
    • Andrade, D.1    Redecha, P.B.2    Vukelic, M.3
  • 50
    • 84866034943 scopus 로고    scopus 로고
    • Graft versus host disease in the bone marrow, liver and thymus humanized mouse model
    • [e44664]
    • Greenblatt M.B., Vrbanac V., Tivey T., Tsang K., Tager A.M., Aliprantis A.O. Graft versus host disease in the bone marrow, liver and thymus humanized mouse model. PLoS One 2012, 7:1-9. [e44664].
    • (2012) PLoS One , vol.7 , pp. 1-9
    • Greenblatt, M.B.1    Vrbanac, V.2    Tivey, T.3    Tsang, K.4    Tager, A.M.5    Aliprantis, A.O.6
  • 51
    • 84862154105 scopus 로고    scopus 로고
    • Histological assessment of the sclerotic graft-versus-host response in the humanized RAG2-/-gammac-/- mouse model
    • Hogenes M.C., van Dorp S., van Kuik J., et al. Histological assessment of the sclerotic graft-versus-host response in the humanized RAG2-/-gammac-/- mouse model. Biol Blood Marrow Transplant 2012, 18:1023-1035.
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. 1023-1035
    • Hogenes, M.C.1    van Dorp, S.2    van Kuik, J.3
  • 52
    • 0141798566 scopus 로고    scopus 로고
    • Immunopathology of human T cell responses to skin, artery and endothelial cell grafts in the human peripheral blood lymphocyte/severe combined immunodeficient mouse
    • Pober J.S., Bothwell A.L., Lorber M.I., McNiff J.M., Schechner J.S., Tellides G. Immunopathology of human T cell responses to skin, artery and endothelial cell grafts in the human peripheral blood lymphocyte/severe combined immunodeficient mouse. Springer Semin Immunopathol 2003, 25:167-180.
    • (2003) Springer Semin Immunopathol , vol.25 , pp. 167-180
    • Pober, J.S.1    Bothwell, A.L.2    Lorber, M.I.3    McNiff, J.M.4    Schechner, J.S.5    Tellides, G.6
  • 53
    • 84866089011 scopus 로고    scopus 로고
    • The Registry of the International Society for Heart and Lung Transplantation: 29th official adult heart transplant report-2012
    • Stehlik J., Edwards L.B., Kucheryavaya A.Y., et al. The Registry of the International Society for Heart and Lung Transplantation: 29th official adult heart transplant report-2012. J Heart Lung Transplant 2012, 31:1052-1064.
    • (2012) J Heart Lung Transplant , vol.31 , pp. 1052-1064
    • Stehlik, J.1    Edwards, L.B.2    Kucheryavaya, A.Y.3
  • 55
    • 0032696447 scopus 로고    scopus 로고
    • Transplantation tolerance-where do we stand?
    • Waldmann H. Transplantation tolerance-where do we stand?. Nat Med 1999, 5:1245-1248.
    • (1999) Nat Med , vol.5 , pp. 1245-1248
    • Waldmann, H.1
  • 56
    • 33750871515 scopus 로고    scopus 로고
    • Smooth muscle cell proliferation but not neointimal formation is dependent on alloantibody in a murine model of intimal hyperplasia
    • Soleimani B., Katopodis A., Wieczorek G., George A.J., Hornick P.I., Heusser C. Smooth muscle cell proliferation but not neointimal formation is dependent on alloantibody in a murine model of intimal hyperplasia. Clin Exp Immunol 2006, 146:509-517.
    • (2006) Clin Exp Immunol , vol.146 , pp. 509-517
    • Soleimani, B.1    Katopodis, A.2    Wieczorek, G.3    George, A.J.4    Hornick, P.I.5    Heusser, C.6
  • 57
    • 66149100472 scopus 로고    scopus 로고
    • Graft vascular disease: immune response meets the vessel wall
    • Mitchell R.N. Graft vascular disease: immune response meets the vessel wall. Annu Rev Pathol 2009, 4:19-47.
    • (2009) Annu Rev Pathol , vol.4 , pp. 19-47
    • Mitchell, R.N.1
  • 58
    • 77950022680 scopus 로고    scopus 로고
    • Development of transplant vasculopathy in aortic allografts correlates with neointimal smooth muscle cell proliferative capacity and fibrocyte frequency
    • Onuta G., van Ark J., Rienstra H., et al. Development of transplant vasculopathy in aortic allografts correlates with neointimal smooth muscle cell proliferative capacity and fibrocyte frequency. Atherosclerosis 2010, 209:393-402.
    • (2010) Atherosclerosis , vol.209 , pp. 393-402
    • Onuta, G.1    van Ark, J.2    Rienstra, H.3
  • 59
    • 77953808089 scopus 로고    scopus 로고
    • Rag2-/- gamma-chain-/- mice as hosts for human vessel transplantation and allogeneic human leukocyte reconstitution
    • Abele-Ohl S., Leis M., Mahmoudian S., Weyand M., Stamminger T., Ensminger S.M. Rag2-/- gamma-chain-/- mice as hosts for human vessel transplantation and allogeneic human leukocyte reconstitution. Transpl Immunol 2010, 23:59-64.
    • (2010) Transpl Immunol , vol.23 , pp. 59-64
    • Abele-Ohl, S.1    Leis, M.2    Mahmoudian, S.3    Weyand, M.4    Stamminger, T.5    Ensminger, S.M.6
  • 60
    • 84857195891 scopus 로고    scopus 로고
    • Transforming growth factor beta expression by human vascular cells inhibits interferon gamma production and arterial media injury by alloreactive memory T cells
    • Lebastchi A.H., Khan S.F., Qin L., et al. Transforming growth factor beta expression by human vascular cells inhibits interferon gamma production and arterial media injury by alloreactive memory T cells. Am J Transplant 2011, 11:2332-2341.
    • (2011) Am J Transplant , vol.11 , pp. 2332-2341
    • Lebastchi, A.H.1    Khan, S.F.2    Qin, L.3
  • 61
    • 77954539326 scopus 로고    scopus 로고
    • In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells
    • Nadig S.N., Wieckiewicz J., Wu D.C., et al. In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells. Nat Med 2010, 16:809-813.
    • (2010) Nat Med , vol.16 , pp. 809-813
    • Nadig, S.N.1    Wieckiewicz, J.2    Wu, D.C.3
  • 62
    • 84860871911 scopus 로고    scopus 로고
    • Human allograft rejection in humanized mice: a historical perspective
    • Brehm M.A., Shultz L.D. Human allograft rejection in humanized mice: a historical perspective. Cell Mol Immunol 2012, 9:225-231.
    • (2012) Cell Mol Immunol , vol.9 , pp. 225-231
    • Brehm, M.A.1    Shultz, L.D.2
  • 63
    • 84878511592 scopus 로고    scopus 로고
    • Amnion-derived multipotent progenitor cells support allograft tolerance induction
    • Anam K., Lazdun Y., Davis P.M., Banas R.A., Elster E.A., Davis T.A. Amnion-derived multipotent progenitor cells support allograft tolerance induction. Am J Transplant 2013, 13:1416-1428.
    • (2013) Am J Transplant , vol.13 , pp. 1416-1428
    • Anam, K.1    Lazdun, Y.2    Davis, P.M.3    Banas, R.A.4    Elster, E.A.5    Davis, T.A.6
  • 64
    • 84883744147 scopus 로고    scopus 로고
    • Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination
    • Coluccio A., Miselli F., Lombardo A., et al. Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination. Mol Ther 2013, 21:1695-1704.
    • (2013) Mol Ther , vol.21 , pp. 1695-1704
    • Coluccio, A.1    Miselli, F.2    Lombardo, A.3
  • 65
    • 77952008607 scopus 로고    scopus 로고
    • CD20, AIF-1, and TGF-beta in graft-versus-host disease: a study of mRNA expression in histologically matched skin biopsies
    • Wu J.M., Thoburn C.J., Wisell J., Farmer E.R., Hess A.D. CD20, AIF-1, and TGF-beta in graft-versus-host disease: a study of mRNA expression in histologically matched skin biopsies. Mod Pathol 2010, 23:720-728.
    • (2010) Mod Pathol , vol.23 , pp. 720-728
    • Wu, J.M.1    Thoburn, C.J.2    Wisell, J.3    Farmer, E.R.4    Hess, A.D.5
  • 66
    • 0034642570 scopus 로고    scopus 로고
    • Interferon-gamma elicits arteriosclerosis in the absence of leukocytes
    • Tellides G., Tereb D.A., Kirkiles-Smith N.C., et al. Interferon-gamma elicits arteriosclerosis in the absence of leukocytes. Nature 2000, 403:207-211.
    • (2000) Nature , vol.403 , pp. 207-211
    • Tellides, G.1    Tereb, D.A.2    Kirkiles-Smith, N.C.3
  • 67
    • 0033608755 scopus 로고    scopus 로고
    • Human allogeneic vascular rejection after arterial transplantation and peripheral lymphoid reconstitution in severe combined immunodeficient mice
    • Lorber M.I., Wilson J.H., Robert M.E., et al. Human allogeneic vascular rejection after arterial transplantation and peripheral lymphoid reconstitution in severe combined immunodeficient mice. Transplantation 1999, 67:897-903.
    • (1999) Transplantation , vol.67 , pp. 897-903
    • Lorber, M.I.1    Wilson, J.H.2    Robert, M.E.3
  • 68
    • 79956272192 scopus 로고    scopus 로고
    • Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection
    • [83ra40]
    • Feng G., Nadig S.N., Backdahl L., et al. Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection. Sci Transl Med 2011, 3:1-10. [83ra40].
    • (2011) Sci Transl Med , vol.3 , pp. 1-10
    • Feng, G.1    Nadig, S.N.2    Backdahl, L.3
  • 69
    • 59649084429 scopus 로고    scopus 로고
    • Development of a humanized mouse model to study the role of macrophages in allograft injury
    • Kirkiles-Smith N.C., Harding M.J., Shepherd B.R., et al. Development of a humanized mouse model to study the role of macrophages in allograft injury. Transplantation 2009, 87:189-197.
    • (2009) Transplantation , vol.87 , pp. 189-197
    • Kirkiles-Smith, N.C.1    Harding, M.J.2    Shepherd, B.R.3
  • 70
    • 4344574035 scopus 로고    scopus 로고
    • Near completely humanized liver in mice shows human-type metabolic responses to drugs
    • Tateno C., Yoshizane Y., Saito N., et al. Near completely humanized liver in mice shows human-type metabolic responses to drugs. Am J Pathol 2004, 165:901-912.
    • (2004) Am J Pathol , vol.165 , pp. 901-912
    • Tateno, C.1    Yoshizane, Y.2    Saito, N.3
  • 71
    • 30944468404 scopus 로고    scopus 로고
    • Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus
    • Tsuge M., Hiraga N., Takaishi H., et al. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus. Hepatology 2005, 42:1046-1054.
    • (2005) Hepatology , vol.42 , pp. 1046-1054
    • Tsuge, M.1    Hiraga, N.2    Takaishi, H.3
  • 72
    • 70449381373 scopus 로고    scopus 로고
    • Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice
    • Ohira M., Ishiyama K., Tanaka Y., et al. Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice. J Clin Invest 2009, 119:3226-3235.
    • (2009) J Clin Invest , vol.119 , pp. 3226-3235
    • Ohira, M.1    Ishiyama, K.2    Tanaka, Y.3
  • 74
    • 79951576827 scopus 로고    scopus 로고
    • The reconstituted 'humanized liver' in TK-NOG mice is mature and functional
    • Hasegawa M., Kawai K., Mitsui T., et al. The reconstituted 'humanized liver' in TK-NOG mice is mature and functional. Biochem Biophys Res Commun 2011, 405:405-410.
    • (2011) Biochem Biophys Res Commun , vol.405 , pp. 405-410
    • Hasegawa, M.1    Kawai, K.2    Mitsui, T.3
  • 75
    • 0028878052 scopus 로고
    • Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect
    • Goldman M.J., Yang Y., Wilson J.M. Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect. Nat Genet 1995, 9:126-131.
    • (1995) Nat Genet , vol.9 , pp. 126-131
    • Goldman, M.J.1    Yang, Y.2    Wilson, J.M.3
  • 77
    • 0038319175 scopus 로고    scopus 로고
    • Human fetal trachea-SCID mouse xenografts: efficacy of vesicular stomatitis virus-G pseudotyped lentiviral-mediated gene transfer
    • Lim F.Y., Kobinger G.P., Weiner D.J., Radu A., Wilson J.M., Crombleholme T.M. Human fetal trachea-SCID mouse xenografts: efficacy of vesicular stomatitis virus-G pseudotyped lentiviral-mediated gene transfer. J Pediatr Surg 2003, 38:834-839.
    • (2003) J Pediatr Surg , vol.38 , pp. 834-839
    • Lim, F.Y.1    Kobinger, G.P.2    Weiner, D.J.3    Radu, A.4    Wilson, J.M.5    Crombleholme, T.M.6
  • 78
    • 84865289880 scopus 로고    scopus 로고
    • Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: implications for in utero gene therapy for cystic fibrosis
    • [e43633]
    • Keswani S.G., Balaji S., Le L., et al. Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: implications for in utero gene therapy for cystic fibrosis. PLoS One 2012, 7:1-10. [e43633].
    • (2012) PLoS One , vol.7 , pp. 1-10
    • Keswani, S.G.1    Balaji, S.2    Le, L.3
  • 79
    • 78751486420 scopus 로고    scopus 로고
    • Submucosal gland development in the human fetal trachea xenograft model: implications for fetal gene therapy
    • Keswani S.G., Le L.D., Morris L.M., et al. Submucosal gland development in the human fetal trachea xenograft model: implications for fetal gene therapy. J Pediatr Surg Jan 2011, 46:33-38.
    • (2011) J Pediatr Surg , vol.46 , pp. 33-38
    • Keswani, S.G.1    Le, L.D.2    Morris, L.M.3
  • 80
    • 84875283930 scopus 로고    scopus 로고
    • Rejection of tracheal allograft by intrapulmonary lymphoid neogenesis in the absence of secondary lymphoid organs
    • Wagnetz D., Sato M., Hirayama S., et al. Rejection of tracheal allograft by intrapulmonary lymphoid neogenesis in the absence of secondary lymphoid organs. Transplantation Jun 27 2012, 93:1212-1220.
    • (2012) Transplantation , vol.93 , pp. 1212-1220
    • Wagnetz, D.1    Sato, M.2    Hirayama, S.3
  • 81
    • 84860863470 scopus 로고    scopus 로고
    • Studying human immunology and immunopathology in humanized mice transplanted with human lymphoid tissues and immune cells
    • Su L. Studying human immunology and immunopathology in humanized mice transplanted with human lymphoid tissues and immune cells. Cell Mol Immunol May 2012, 9:191-192.
    • (2012) Cell Mol Immunol , vol.9 , pp. 191-192
    • Su, L.1


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