Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination

Molecular Therapy

Volumn 21, Issue 9, 2013, Pages 1695-1704

  Coluccio, Andrea ^a   Miselli, Francesca ^a   Lombardo, Angelo ^b   Marconi, Alessandra ^a   Malagoli Tagliazucchi, Guidantonio ^a   Gonçalves, Manuel A ^c   Pincelli, Carlo ^a   Maruggi, Giulietta ^a,f   Del Rio, Marcela ^d   Naldini, Luigi ^b   Larcher, Fernando ^d   Mavilio, Fulvio ^a,e   Recchia, Alessandra ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d CIEMAT   (Spain)

^e GÉNÉTHON   (France)

^f NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENO ASSOCIATED VIRUS INTEGRATION SITE 1; ADENOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN; INTEGRATION DEFECTIVE LENTIVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS VECTOR; ZINC FINGER NUCLEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL IMMORTALIZATION; CELL TRANSPLANTATION; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA INTEGRATION; DNA MODIFICATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENGRAFTMENT; EPITHELIAL STEM CELL; FEMALE; GENE ADDITION; GENE CASSETTE; GENE LOCUS; HISTOPATHOLOGY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; KERATINOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SKIN INJURY; SKIN TRANSPLANTATION; STEM CELL; VIRAL GENE DELIVERY SYSTEM;

ADENO-ASSOCIATED VIRUS; MUS;

ANIMALS; CELL LINE; CELL TRANSPLANTATION; CELLS, CULTURED; DEPENDOVIRUS; ENDONUCLEASES; GENE TARGETING; GENETIC VECTORS; HOMOLOGOUS RECOMBINATION; HUMANS; KERATINOCYTES; MICE; STEM CELLS; TRANSDUCTION, GENETIC; VIRUS INTEGRATION; ZINC FINGERS;

EID: 84883744147     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2013.143     Document Type: Article

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