메뉴 건너뛰기




Volumn 164, Issue 5, 2000, Pages 2496-2507

NOD/LtSz-Rag1(null) mice: An immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DISEASE MODEL; GENE REARRANGEMENT; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE FUNCTION; MOUSE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; SPLEEN CELL; STRAIN DIFFERENCE; AGING; ANIMAL; BLOOD; C57BL MOUSE; CYTOLOGY; ERYTHROCYTE COUNT; FEMALE; FETUS BLOOD; GENE; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOLOGY; IMMUNOPHENOTYPING; LEUKOCYTE COUNT; LONGEVITY; LYMPHOID TISSUE; LYMPHOMA; MALE; METHODOLOGY; MONONUCLEAR CELL; MOUSE MUTANT; NATURAL KILLER CELL; NONOBESE DIABETIC MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; RADIATION DOSE; SPLEEN; T LYMPHOCYTE; TRANSPLANTATION;

EID: 0034144688     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2496     Document Type: Article
Times cited : (138)

References (55)
  • 1
    • 0029086940 scopus 로고
    • High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to HIV-1 infection in NOD/LtSz-scid/ scid mice
    • Hesselton, R M., D. L. Greiner, J. P. Mordes, T. V. Rajan, J. L. Sullivan, and L. D. Shultz. 1995. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to HIV-1 infection in NOD/LtSz-scid/ scid mice. J. Infect. Dis. 172:774.
    • (1995) J. Infect. Dis. , vol.172 , pp. 774
    • Hesselton, R.M.1    Greiner, D.L.2    Mordes, J.P.3    Rajan, T.V.4    Sullivan, J.L.5    Shultz, L.D.6
  • 3
    • 0023734130 scopus 로고
    • Transfer of a functional human immune system to mice with severe combined immunodeficiency
    • Mosier, D. E., R. J. Gulizia, S. M. Baird, and D. B. Wilson. 1988. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 335:256.
    • (1988) Nature , vol.335 , pp. 256
    • Mosier, D.E.1    Gulizia, R.J.2    Baird, S.M.3    Wilson, D.B.4
  • 4
    • 0026581239 scopus 로고
    • Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
    • Lapidot, T., F. Pflumio, M. Deodens, B. Murdoch, D. E. Williams, and J. E. Dick. 1992. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science 255:1137.
    • (1992) Science , vol.255 , pp. 1137
    • Lapidot, T.1    Pflumio, F.2    Deodens, M.3    Murdoch, B.4    Williams, D.E.5    Dick, J.E.6
  • 5
    • 0023753744 scopus 로고
    • The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
    • McCune, J. M., R. Namikawa, H. Kaneshima, L. D. Shultz, M. Lieberman, and I. L. Weissman. 1988. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 241:1632.
    • (1988) Science , vol.241 , pp. 1632
    • McCune, J.M.1    Namikawa, R.2    Kaneshima, H.3    Shultz, L.D.4    Lieberman, M.5    Weissman, I.L.6
  • 9
    • 0031805237 scopus 로고    scopus 로고
    • SCID mouse models of human stem cell engraftment
    • Greiner, D. L., R. A. Hesselton, and L. D. Shultz. 1998. SCID mouse models of human stem cell engraftment. Stem Cells 16:166.
    • (1998) Stem Cells , vol.16 , pp. 166
    • Greiner, D.L.1    Hesselton, R.A.2    Shultz, L.D.3
  • 12
    • 0030219809 scopus 로고    scopus 로고
    • Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice
    • Christianson, S. W., D. L. Greiner, I. B. Schweitzer, B. Gott, G. L. Beamer, P. A. Schweitzer, R. A. Hesselton, and L. D. Shultz. 1996. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell. Immunol. 171:186.
    • (1996) Cell. Immunol. , vol.171 , pp. 186
    • Christianson, S.W.1    Greiner, D.L.2    Schweitzer, I.B.3    Gott, B.4    Beamer, G.L.5    Schweitzer, P.A.6    Hesselton, R.A.7    Shultz, L.D.8
  • 13
    • 0028913342 scopus 로고
    • Engraftment of immune-deficient mice with primitive hematopoietic cells from β-thalassemia and sickle cell anemia patients: Implications for evaluating human gene therapy protocols
    • Larochelle, A., J. Vormoor, T. Lapidot, G. Sher, T. Furukawa, Q. Li, L. D. Shultz, N. F. Olivieri, G. Stamatoyannopoulos, and J. E. Dick. 1995. Engraftment of immune-deficient mice with primitive hematopoietic cells from β-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols. Hum. Mol. Genet. 4:163.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 163
    • Larochelle, A.1    Vormoor, J.2    Lapidot, T.3    Sher, G.4    Furukawa, T.5    Li, Q.6    Shultz, L.D.7    Olivieri, N.F.8    Stamatoyannopoulos, G.9    Dick, J.E.10
  • 14
    • 0029826591 scopus 로고    scopus 로고
    • Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells
    • Pflumio, F., B. Izac, A. Katz, L. D. Shultz, W. Vainchenker, and L. Coulombel. 1996. Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells. Blood 88:3731.
    • (1996) Blood , vol.88 , pp. 3731
    • Pflumio, F.1    Izac, B.2    Katz, A.3    Shultz, L.D.4    Vainchenker, W.5    Coulombel, L.6
  • 16
    • 0030925298 scopus 로고    scopus 로고
    • Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow trans-planted into immunodeficient mice
    • Cashman, J. D., T. Lapidot, J. C. Wang, M. Doedens, L. D. Shultz, P. Lansdorp, J. E. Dick, and C. J. Eaves. 1997. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow trans-planted into immunodeficient mice. Blood 89:4307.
    • (1997) Blood , vol.89 , pp. 4307
    • Cashman, J.D.1    Lapidot, T.2    Wang, J.C.3    Doedens, M.4    Shultz, L.D.5    Lansdorp, P.6    Dick, J.E.7    Eaves, C.J.8
  • 17
    • 0031956277 scopus 로고    scopus 로고
    • Mature human hematopoietic cells in donor bone marrow complicate interpretation of stem/ progenitor cell assays in xenogeneic hematopoietic chimeras
    • Ramirez, M., G. A. Rottman, L. D. Shultz, and C. I. Civin. 1998. Mature human hematopoietic cells in donor bone marrow complicate interpretation of stem/ progenitor cell assays in xenogeneic hematopoietic chimeras. Exp. Hematol. 26: 332.
    • (1998) Exp. Hematol. , vol.26 , pp. 332
    • Ramirez, M.1    Rottman, G.A.2    Shultz, L.D.3    Civin, C.I.4
  • 19
    • 0026554156 scopus 로고
    • The NOD-scid mouse: A model for spontaneous thymomagenesis associated with immuno-deficiency
    • Prochazka, M., H. R. Gaskins, L. D. Shultz, and E. H. Leiter. 1992. The NOD-scid mouse: a model for spontaneous thymomagenesis associated with immuno-deficiency. Proc. Natl. Acad. Sci. USA 89:3290.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3290
    • Prochazka, M.1    Gaskins, H.R.2    Shultz, L.D.3    Leiter, E.H.4
  • 22
    • 0027932794 scopus 로고
    • Engraftment of human lymphocytes and thyroid tissue into scid and rag2-deficient mice: Absent progression of lymphocytic infiltration
    • Martin, A., M. Valentine, P. Unger, S. W. Yeung, L. D. Shultz, and T. F. Davies. 1994. Engraftment of human lymphocytes and thyroid tissue into scid and rag2-deficient mice: absent progression of lymphocytic infiltration. J. Clin. Endocrinol. Metab. 79:716.
    • (1994) J. Clin. Endocrinol. Metab. , vol.79 , pp. 716
    • Martin, A.1    Valentine, M.2    Unger, P.3    Yeung, S.W.4    Shultz, L.D.5    Davies, T.F.6
  • 23
    • 0029591868 scopus 로고
    • Engraftment and humoral immunity in SCID and RAG-2-deficient mice transplanted with human peripheral blood lymphocytes
    • Steinsvik, T. E., P. I. Gaarder, I. S. Aaberge, and M. Lovik. 1995. Engraftment and humoral immunity in SCID and RAG-2-deficient mice transplanted with human peripheral blood lymphocytes. Scand. J. Immunol. 42:607.
    • (1995) Scand. J. Immunol. , vol.42 , pp. 607
    • Steinsvik, T.E.1    Gaarder, P.I.2    Aaberge, I.S.3    Lovik, M.4
  • 24
    • 0026584129 scopus 로고
    • Defective repair of radiation-induced chromosomal damage in scid/scid mice
    • Disney, J. E., A. L. Barth, and L. D. Shultz. 1992. Defective repair of radiation-induced chromosomal damage in scid/scid mice. Cytogenet. Cell Genet. 59:39.
    • (1992) Cytogenet. Cell Genet. , vol.59 , pp. 39
    • Disney, J.E.1    Barth, A.L.2    Shultz, L.D.3
  • 25
    • 0025011134 scopus 로고
    • The scid mutation in mice causes a general defect in DNA repair
    • Fulop, G. M., and R. A. Phillips. 1990. The scid mutation in mice causes a general defect in DNA repair. Nature 347:479.
    • (1990) Nature , vol.347 , pp. 479
    • Fulop, G.M.1    Phillips, R.A.2
  • 26
    • 0026071588 scopus 로고
    • Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
    • Biedermann, K. A., J. R. Sun, A. J. Giaccia, L. M. Tosto, and J. M. Brown. 1991. Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 88:1394.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1394
    • Biedermann, K.A.1    Sun, J.R.2    Giaccia, A.J.3    Tosto, L.M.4    Brown, J.M.5
  • 29
    • 0018652555 scopus 로고
    • Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens
    • Ledbetter, J., and L. Herzenberg. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:63.
    • (1979) Immunol. Rev. , vol.47 , pp. 63
    • Ledbetter, J.1    Herzenberg, L.2
  • 30
    • 0020593691 scopus 로고
    • Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development
    • Coffman, R. L. 1982. Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development. Immunol. Rev. 69:5.
    • (1982) Immunol. Rev. , vol.69 , pp. 5
    • Coffman, R.L.1
  • 31
    • 0019364279 scopus 로고
    • b haplotype reveal genetic control of isotope expression
    • b haplotype reveal genetic control of isotope expression. J. Immunol. 126:317.
    • (1981) J. Immunol. , vol.126 , pp. 317
    • Ozato, K.1    Sachs, D.H.2
  • 34
    • 0025062703 scopus 로고
    • A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
    • Ikuta, K., T. Kina, I. MacNeil, N. Uchida, B. Peault, Y. H. Chien, and I. L. Weissman. 1990. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell 62:863.
    • (1990) Cell , vol.62 , pp. 863
    • Ikuta, K.1    Kina, T.2    MacNeil, I.3    Uchida, N.4    Peault, B.5    Chien, Y.H.6    Weissman, I.L.7
  • 36
    • 0027178774 scopus 로고
    • Human peripheral blood xenografts in the SCID mouse: Characterization of immunological reconstitution
    • Hesselton, R. M., R. A. Koup, M. A. Cromwell, B. S. Graham, M. Johns, and J. L. Sullivan. 1993. Human peripheral blood xenografts in the SCID mouse: characterization of immunological reconstitution. J. Infect. Dis. 168:630.
    • (1993) J. Infect. Dis. , vol.168 , pp. 630
    • Hesselton, R.M.1    Koup, R.A.2    Cromwell, M.A.3    Graham, B.S.4    Johns, M.5    Sullivan, J.L.6
  • 37
    • 0028328981 scopus 로고
    • Quantitative assessment of human immunodeficiency virus type 1 replication in human xenografts of acutely infected Hu-PBL-SCID mice
    • Koup, R. A., R. M. Hesselton, J. T. Safrit, M. Somasundaran, and J. L. Sullivan. 1994. Quantitative assessment of human immunodeficiency virus type 1 replication in human xenografts of acutely infected Hu-PBL-SCID mice. AIDS Res. Hum. Retroviruses 10:279.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 279
    • Koup, R.A.1    Hesselton, R.M.2    Safrit, J.T.3    Somasundaran, M.4    Sullivan, J.L.5
  • 39
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger, M. A., D. G. Schatz, C. Gorka, and D. Baltimore. 1990. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 248:1517.
    • (1990) Science , vol.248 , pp. 1517
    • Oettinger, M.A.1    Schatz, D.G.2    Gorka, C.3    Baltimore, D.4
  • 40
    • 0030272590 scopus 로고    scopus 로고
    • Developmental regulation of V(D)J recombination and lymphocyte differentiation
    • Willerford, D. M., W. Swat, and F. W. Alt. 1996. Developmental regulation of V(D)J recombination and lymphocyte differentiation. Curr. Opin. Genet. Dev. 6:603.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 603
    • Willerford, D.M.1    Swat, W.2    Alt, F.W.3
  • 42
    • 0030419923 scopus 로고    scopus 로고
    • Identification of the catalytic subunit of DNA dependent protein kinase as the product of the mouse scid gene
    • Jeggo, P. A., S. P. Jackson, and G. E. Taccioli. 1996. Identification of the catalytic subunit of DNA dependent protein kinase as the product of the mouse scid gene. Curr. Top. Microbiol. Immunol. 217:79.
    • (1996) Curr. Top. Microbiol. Immunol. , vol.217 , pp. 79
    • Jeggo, P.A.1    Jackson, S.P.2    Taccioli, G.E.3
  • 44
    • 0028343691 scopus 로고
    • Human primary immune response in SCID mice engrafted with human peripheral blood lymphocytes
    • Sandhu, J., B. Shpitz, S. Gallinger, and N. Hozumi. 1994. Human primary immune response in SCID mice engrafted with human peripheral blood lymphocytes. J. Immunol. 152:3806.
    • (1994) J. Immunol. , vol.152 , pp. 3806
    • Sandhu, J.1    Shpitz, B.2    Gallinger, S.3    Hozumi, N.4
  • 45
    • 0024407796 scopus 로고
    • Immunobiology of bone marrow transplantation: Studies using scid mice
    • Murphy, W. J., V. Kumar, and M. Bennett. 1989. Immunobiology of bone marrow transplantation: studies using scid mice. Curr. Top. Microbiol. Immunol. 152:251.
    • (1989) Curr. Top. Microbiol. Immunol. , vol.152 , pp. 251
    • Murphy, W.J.1    Kumar, V.2    Bennett, M.3
  • 46
    • 0025264240 scopus 로고
    • An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells
    • Murphy, W. J., V. Kumar, J. C. Cope, and M. Bennett. 1990. An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells. J. Immunol. 144:3305.
    • (1990) J. Immunol. , vol.144 , pp. 3305
    • Murphy, W.J.1    Kumar, V.2    Cope, J.C.3    Bennett, M.4
  • 52
    • 0025811882 scopus 로고
    • The scid mouse mutant: Definition, characterization, and potential uses
    • Bosma, M. J., and A. M. Carroll. 1991. The scid mouse mutant: definition, characterization, and potential uses. Annu. Rev. Immunol. 9:323.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 323
    • Bosma, M.J.1    Carroll, A.M.2
  • 54
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated diabetes in nonobese diabetic mice
    • Serreze, D. V., S. A. Fleming, D. S. Chapman, S. D. Richard, E. H. Leiter, and R. M. Tisch. 1998. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated diabetes in nonobese diabetic mice. J. Immunol. 161:3912.
    • (1998) J. Immunol. , vol.161 , pp. 3912
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, D.S.3    Richard, S.D.4    Leiter, E.H.5    Tisch, R.M.6
  • 55
    • 0029826977 scopus 로고    scopus 로고
    • B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new "speed congenic" stock of NOD.Ig mu null mice
    • Serreze, D. V., H. D. Chapman, D. S. Varnum, M. S. Hanson, P. C. Reifsnyder, S. D. Richard, S. A. Fleming, E. H. Leiter, and L. D. Shultz. 1996. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J. Exp. Med. 184:2049.
    • (1996) J. Exp. Med. , vol.184 , pp. 2049
    • Serreze, D.V.1    Chapman, H.D.2    Varnum, D.S.3    Hanson, M.S.4    Reifsnyder, P.C.5    Richard, S.D.6    Fleming, S.A.7    Leiter, E.H.8    Shultz, L.D.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.