Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: Implications for in Utero gene therapy for cystic fibrosis

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Keswani, Sundeep G ^a,b   Balaji, Swathi ^a   Le, Louis ^a   Leung, Alice ^a   Katz, Anna B ^b   Lim, Foong Yen ^a,b   Habli, Mounira ^a   Jones, Helen N ^a   Wilson, James M ^c   Crombleholme, Timothy M ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; LAMININ RECEPTOR; PARVOVIRUS VECTOR; PROTEOHEPARAN SULFATE;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 2; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENGRAFTMENT; FETUS; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN TISSUE; IN UTERO GENE THERAPY; MOUSE; NONHUMAN; PSEUDOTYPING; REPORTER GENE; RESPIRATORY EPITHELIUM; SCID MOUSE; TRACHEA; TRACHEA GRAFT; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; XENOGRAFT; XENOTRANSPLANTATION;

ANIMALS; CYSTIC FIBROSIS; DEPENDOVIRUS; FETAL THERAPIES; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; MICE; MICE, SCID; TRACHEA; TRANSPLANTATION, HETEROLOGOUS;

EID: 84865289880     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043633     Document Type: Article

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