메뉴 건너뛰기




Volumn 26, Issue 1, 2014, Pages 1-15

Cross-talk between neurons and astrocytes in response to bilirubin: Adverse secondary impacts

Author keywords

Astrocyte activation; Co culture; Glycoursodeoxycholic acid; Neuron astrocyte signaling; Neuronal dysfunction; Unconjugated bilirubin

Indexed keywords

BILIRUBIN; GLYCOURSODEOXYCHOLIC ACID; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; NITRIC OXIDE; PROTEIN S100B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID DERIVATIVE; ANTIOXIDANT; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; NEUROPROTECTIVE AGENT; S100B PROTEIN, RAT; URSODEOXYCHOLIC ACID;

EID: 84903741375     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-013-9427-y     Document Type: Article
Times cited : (12)

References (89)
  • 1
    • 67650088580 scopus 로고    scopus 로고
    • Unbound (free) bilirubin: Improving the paradigm for evaluating neonatal jaundice
    • Ahlfors CE, Wennberg RP, Ostrow JD, Tiribelli C (2009) Unbound (free) bilirubin: improving the paradigm for evaluating neonatal jaundice. Clin Chem 55(7):1288-1299
    • (2009) Clin Chem , vol.55 , Issue.7 , pp. 1288-1299
    • Ahlfors, C.E.1    Wennberg, R.P.2    Ostrow, J.D.3    Tiribelli, C.4
  • 2
    • 0342470474 scopus 로고    scopus 로고
    • Influence of factors secreted by Wobbler astrocytes on neuronal and motoneuronal survival
    • DOI 10.1002/(SICI)1097-4547(20000101)59:1<100::AID
    • Ait-Ikhlef A, Hantaz-Ambroise D, Henderson CE, Rieger F (2000) Influence of factors secreted by wobbler astrocytes on neuronal and motoneuronal survival. J Neurosci Res 59(1):100-106 (Pubitemid 30038869)
    • (2000) Journal of Neuroscience Research , vol.59 , Issue.1 , pp. 100-106
    • Ait-Ikhlef, A.1    Hantaz-Ambroise, D.2    Henderson, C.E.3    Rieger, F.4
  • 3
    • 77749336627 scopus 로고    scopus 로고
    • Amyloid-β aggregates cause alterations of astrocytic metabolic phenotype: Impact on neuronal viability
    • Allaman I, Gavillet M, Belanger M, Laroche T, Viertl D, Lashuel HA, Magistretti PJ (2010) Amyloid-β aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability. J Neurosci 30(9):3326-3338
    • (2010) J Neurosci , vol.30 , Issue.9 , pp. 3326-3338
    • Allaman, I.1    Gavillet, M.2    Belanger, M.3    Laroche, T.4    Viertl, D.5    Lashuel, H.A.6    Magistretti, P.J.7
  • 4
    • 79551591722 scopus 로고    scopus 로고
    • Astrocyte-neuron metabolic relationships: For better and for worse
    • Allaman I, Belanger M, Magistretti PJ (2011) Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci 34(2):76-87
    • (2011) Trends Neurosci , vol.34 , Issue.2 , pp. 76-87
    • Allaman, I.1    Belanger, M.2    Magistretti, P.J.3
  • 5
    • 80054070949 scopus 로고    scopus 로고
    • Functional contributions of astrocytes in synchronization of a neuronal network model
    • Amiri M, Bahrami F, Janahmadi M (2012) Functional contributions of astrocytes in synchronization of a neuronal network model. J Theor Biol 292:60-70
    • (2012) J Theor Biol , vol.292 , pp. 60-70
    • Amiri, M.1    Bahrami, F.2    Janahmadi, M.3
  • 6
    • 80055120173 scopus 로고    scopus 로고
    • A neuronal and astrocyte coculture assay for high content analysis of neurotoxicity
    • Anderl JL, Redpath S, Ball AJ (2009) A neuronal and astrocyte coculture assay for high content analysis of neurotoxicity. J Vis Exp 27:1173-1180
    • (2009) J Vis Exp , vol.27 , pp. 1173-1180
    • Anderl, J.L.1    Redpath, S.2    Ball, A.J.3
  • 7
    • 0346668359 scopus 로고    scopus 로고
    • Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes
    • DOI 10.1002/glia.10124
    • Bal-Price A, Moneer Z, Brown GC (2002) Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes. Glia 40(3):312-323 (Pubitemid 36010738)
    • (2002) GLIA , vol.40 , Issue.3 , pp. 312-323
    • Bal-Price, A.1    Moneer, Z.2    Brown, G.C.3
  • 9
    • 0343060358 scopus 로고    scopus 로고
    • Roles of nitric oxide in brain hypoxia-ischemia
    • DOI 10.1016/S0005-2728(99)00030-4, PII S0005272899000304
    • Bolaños JP, Almeida A (1999) Roles of nitric oxide in brain hypoxia-ischemia. Biochim Biophys Acta 1411(2-3):415-436 (Pubitemid 29221965)
    • (1999) Biochimica et Biophysica Acta - Bioenergetics , vol.1411 , Issue.2-3 , pp. 415-436
    • Bolanos, J.P.1    Almeida, A.2
  • 10
    • 84866018240 scopus 로고    scopus 로고
    • The evolving landscape of neurotoxicity by unconjugated bilirubin: Role of glial cells and inflammation
    • Brites D (2012) The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation. Front Pharmacol 3:88
    • (2012) Front Pharmacol , vol.3 , pp. 88
    • Brites, D.1
  • 11
    • 0031952407 scopus 로고    scopus 로고
    • Correction of maternal serum bile acid profile during ursodeoxycholic acid therapy in cholestasis of pregnancy
    • DOI 10.1016/S0168-8278(98)80207-9
    • Brites D, Rodrigues CMP, Oliveira N, Cardoso M, Graca LM (1998) Correction ofmaternal serum bile acid profile during ursodeoxycholic acid therapy in cholestasis of pregnancy. J Hepatol 28(1):91-98 (Pubitemid 28122505)
    • (1998) Journal of Hepatology , vol.28 , Issue.1 , pp. 91-98
    • Brites, D.1    Rodrigues, C.M.P.2    Oliveira, N.3    Cardoso, M.D.C.4    Graca, L.M.5
  • 13
    • 36549090063 scopus 로고    scopus 로고
    • Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells
    • DOI 10.1016/j.nbd.2007.07.023, PII S096999610700174X
    • Brito MA, Rosa AI, Falcão AS, Fernandes A, Silva RFM, Butterfield DA, Brites D (2008b) Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells. Neurobiol Dis 29(1):30-40 (Pubitemid 350180480)
    • (2008) Neurobiology of Disease , vol.29 , Issue.1 , pp. 30-40
    • Brito, M.A.1    Rosa, A.I.2    Falcao, A.S.3    Fernandes, A.4    Silva, R.F.M.5    Butterfield, D.A.6    Brites, D.7
  • 14
    • 77956632156 scopus 로고    scopus 로고
    • N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity
    • Brito MA, Vaz AR, Silva SL, Falcão AS, Fernandes A, Silva RFM, Brites D (2010) N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity. Mol Med 16(9-10):372-380
    • (2010) Mol Med , vol.16 , Issue.9-10 , pp. 372-380
    • Brito, M.A.1    Vaz, A.R.2    Silva, S.L.3    Falcão, A.S.4    Fernandes, A.5    Silva, R.F.M.6    Brites, D.7
  • 15
    • 0033032141 scopus 로고    scopus 로고
    • Neurons depend on astrocytes in a coculture system for protection from glutamate toxicity
    • Brown DR (1999) Neurons depend on astrocytes in a coculture system for protection from glutamate toxicity. Mol Cell Neurosci 13(5):379-389
    • (1999) Mol Cell Neurosci , vol.13 , Issue.5 , pp. 379-389
    • Brown, D.R.1
  • 16
    • 0041784698 scopus 로고    scopus 로고
    • Inflammatory Neurodegeneration Mediated by Nitric Oxide, Glutamate, and Mitochondria
    • DOI 10.1385/MN:27:3:325
    • Brown GC, Bal-Price A (2003) Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol Neurobiol 27(3):325-355 (Pubitemid 38156291)
    • (2003) Molecular Neurobiology , vol.27 , Issue.3 , pp. 325-355
    • Brown, G.C.1    Bal-Price, A.2
  • 17
    • 79953205512 scopus 로고    scopus 로고
    • ATP: A ubiquitous gliotransmitter integrating neuronglial networks
    • Butt AM (2011) ATP: a ubiquitous gliotransmitter integrating neuronglial networks. Semin Cell Dev Biol 22(2):205-213
    • (2011) Semin Cell Dev Biol , vol.22 , Issue.2 , pp. 205-213
    • Butt, A.M.1
  • 18
    • 32344449051 scopus 로고    scopus 로고
    • Multidrug resistance associated protein 1 protects against bilirubin-induced cytotoxicity
    • DOI 10.1016/j.febslet.2006.01.056, PII S0014579306001098
    • Calligaris S, Cekic D, Roca-Burgos L, Gerin F, Mazzone G, Ostrow JD, Tiribelli C (2006) Multidrug resistance associated protein 1 protects against bilirubin-induced cytotoxicity. FEBS Lett 580(5):1355-1359 (Pubitemid 43222000)
    • (2006) FEBS Letters , vol.580 , Issue.5 , pp. 1355-1359
    • Calligaris, S.1    Cekic, D.2    Roca-Burgos, L.3    Gerin, F.4    Mazzone, G.5    Ostrow, J.D.6    Tiribelli, C.7
  • 20
    • 0023424871 scopus 로고
    • MAP2 expression and neuritic outgrowth and branching are coregulated through region-specific neuro-astroglial interactions
    • Chamak B, Fellous A, Glowinski J, Prochiantz A (1987) MAP2 expression and neuritic outgrowth and branching are coregulated through region-specific neuro-astroglial interactions. J Neurosci 7(10):3163-3170
    • (1987) J Neurosci , vol.7 , Issue.10 , pp. 3163-3170
    • Chamak, B.1    Fellous, A.2    Glowinski, J.3    Prochiantz, A.4
  • 21
    • 3042599451 scopus 로고    scopus 로고
    • Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats
    • DOI 10.1124/dmd.32.7.734
    • Cherrington NJ, Slitt AL, Li N, Klaassen CD (2004) Lipopolysaccharide- mediated regulation of hepatic transporter mRNA levels in rats. Drug Metab Dispos 32(7):734-741 (Pubitemid 38821875)
    • (2004) Drug Metabolism and Disposition , vol.32 , Issue.7 , pp. 734-741
    • Cherrington, N.J.1    Slitt, A.L.2    Li, N.3    Klaassen, C.D.4
  • 23
    • 39049142508 scopus 로고    scopus 로고
    • Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders
    • DOI 10.1016/j.jns.2007.08.044, PII S0022510X0700620X
    • De Keyser J, Mostert JP, Koch MW (2008) Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders. J Neurol Sci 267(1-2):3-16 (Pubitemid 351248899)
    • (2008) Journal of the Neurological Sciences , vol.267 , Issue.1-2 , pp. 3-16
    • De Keyser, J.1    Mostert, J.P.2    Koch, M.W.3
  • 25
    • 0030772178 scopus 로고    scopus 로고
    • Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency
    • DOI 10.1016/S0006-8993(97)00790-7, PII S0006899397007907
    • Drukarch B, Schepens E, Jongenelen CA, Stoof JC, Langeveld CH (1997) Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency. Brain Res 770(1-2):123-130 (Pubitemid 27468059)
    • (1997) Brain Research , vol.770 , Issue.1-2 , pp. 123-130
    • Drukarch, B.1    Schepens, E.2    Jongenelen, C.A.M.3    Stoof, J.C.4    Langeveld, C.H.5
  • 26
    • 0032528195 scopus 로고    scopus 로고
    • Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species
    • DOI 10.1016/S0891-5849(98)00050-1, PII S0891584998000501
    • Drukarch B, Schepens E, Stoof JC, Langeveld CH, Van Muiswinkel FL (1998) Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species. Free Radic Biol Med 25(2):217-220 (Pubitemid 28293157)
    • (1998) Free Radical Biology and Medicine , vol.25 , Issue.2 , pp. 217-220
    • Drukarch, B.1    Schepens, E.2    Stoof, J.C.3    Langeveld, C.H.4    Van Muiswinkel, F.L.5
  • 27
    • 33750463062 scopus 로고    scopus 로고
    • TNF alpha affects the expression of GFAP and S100B: Implications for Alzheimer's disease
    • DOI 10.1007/s00702-006-0479-5, 100 Years of Alzheimer's Disease
    • Edwards MM, Robinson SR (2006) TNF alpha affects the expression of GFAP and S100B: implications for Alzheimer's disease. J Neural Transm 113(11):1709-1715 (Pubitemid 44657666)
    • (2006) Journal of Neural Transmission , vol.113 , Issue.11 , pp. 1709-1715
    • Edwards, M.M.1    Robinson, S.R.2
  • 28
    • 26944464585 scopus 로고    scopus 로고
    • Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells
    • Falcão AS, Fernandes A, Brito MA, Silva RFM, Brites D (2005) Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells. Neurobiol Dis 20(2):199-206
    • (2005) Neurobiol Dis , vol.20 , Issue.2 , pp. 199-206
    • Falcão, A.S.1    Fernandes, A.2    Brito, M.A.3    Silva, R.F.M.4    Brites, D.5
  • 29
    • 33745401404 scopus 로고    scopus 로고
    • Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state
    • Falcão AS, Fernandes A, Brito MA, Silva RFM, Brites D (2006) Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state. Acta Neuropathol 112(1):95-105
    • (2006) Acta Neuropathol , vol.112 , Issue.1 , pp. 95-105
    • Falcão, A.S.1    Fernandes, A.2    Brito, M.A.3    Silva, R.F.M.4    Brites, D.5
  • 30
    • 33845899686 scopus 로고    scopus 로고
    • Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin
    • Falcão AS, Bellarosa C, Fernandes A, Brito MA, Silva RFM, Tiribelli C, Brites D (2007a) Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin. Neuroscience 144(3):878-888
    • (2007) Neuroscience , vol.144 , Issue.3 , pp. 878-888
    • Falcão, A.S.1    Bellarosa, C.2    Fernandes, A.3    Brito, M.A.4    Silva, R.F.M.5    Tiribelli, C.6    Brites, D.7
  • 31
    • 34248141645 scopus 로고    scopus 로고
    • Apoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulus
    • Falcão AS, Silva RFM, Pancadas S, Fernandes A, Brito MA, Brites D (2007b) Apoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulus. J Neurosci Res 85(6):1229-1239
    • (2007) J Neurosci Res , vol.85 , Issue.6 , pp. 1229-1239
    • Falcão, A.S.1    Silva, R.F.M.2    Pancadas, S.3    Fernandes, A.4    Brito, M.A.5    Brites, D.6
  • 32
    • 84876416140 scopus 로고    scopus 로고
    • Cross-talk between neurons and astrocytes in response to bilirubin: Early beneficial effects
    • Falcão AS, Silva RFM, Vaz AR, Silva SL, Fernandes A, BritesD(2013) Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects. Neurochem Res 38(3):644-659
    • (2013) Neurochem Res , vol.38 , Issue.3 , pp. 644-659
    • Falcão, A.S.1    Silva, R.F.M.2    Vaz, A.R.3    Silva, S.L.4    Fernandes, A.5    Brites, D.6
  • 33
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • DOI 10.1016/j.it.2007.01.005, PII S1471490607000245
    • Farina C, Aloisi F, Meinl E (2007) Astrocytes are active players in cerebral innate immunity. Trends Immunol 28(3):138-145 (Pubitemid 46283692)
    • (2007) Trends in Immunology , vol.28 , Issue.3 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 34
    • 70449389923 scopus 로고    scopus 로고
    • Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents
    • Fernandes A, Brites D (2009) Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents. Curr Pharm Des 15(25):2915-2926
    • (2009) Curr Pharm des , vol.15 , Issue.25 , pp. 2915-2926
    • Fernandes, A.1    Brites, D.2
  • 35
    • 3242679583 scopus 로고    scopus 로고
    • Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS
    • DOI 10.1016/j.jneuroim.2004.04.007, PII S016557280400147X
    • Fernandes A, Silva RFM, Falcão AS, Brito MA, Brites D (2004) Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS. J Neuroimmunol 153(1-2):64-75 (Pubitemid 38950928)
    • (2004) Journal of Neuroimmunology , vol.153 , Issue.1-2 , pp. 64-75
    • Fernandes, A.1    Silva, R.F.M.2    Falcao, A.S.3    Brito, M.A.4    Brites, D.5
  • 37
    • 34548454884 scopus 로고    scopus 로고
    • Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin
    • DOI 10.1097/nen.0b013e3181461c74, PII 0000507220070900000003
    • Fernandes A, Vaz AR, Falcão AS, Silva RFM, Brito MA, Brites D (2007) Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin. J Neuropathol Exp Neurol 66(9):789-798 (Pubitemid 47360954)
    • (2007) Journal of Neuropathology and Experimental Neurology , vol.66 , Issue.9 , pp. 789-798
    • Fernandes, A.1    Vaz, A.R.2    Falcao, A.S.3    Silva, R.F.M.4    Brito, M.A.5    Brites, D.6
  • 40
    • 84858306047 scopus 로고    scopus 로고
    • Antioxidant and bioenergetic coupling between neurons and astrocytes
    • Fernandez-Fernandez S, Almeida A, Bolaños JP (2012) Antioxidant and bioenergetic coupling between neurons and astrocytes. Biochem J 443(1):3-11
    • (2012) Biochem J , vol.443 , Issue.1 , pp. 3-11
    • Fernandez-Fernandez, S.1    Almeida, A.2    Bolaños, J.P.3
  • 43
    • 44949258862 scopus 로고    scopus 로고
    • Biological and methodological features of the measurement of S100B, a putative marker of brain injury
    • Gonçalves CA, Leite MC, Nardin P (2008) Biological and methodological features of the measurement of S100B, a putative marker of brain injury. Clin Biochem 41(10-11):755-763
    • (2008) Clin Biochem , vol.41 , Issue.10-11 , pp. 755-763
    • Gonçalves, C.A.1    Leite, M.C.2    Nardin, P.3
  • 44
    • 0036945342 scopus 로고    scopus 로고
    • Mechanisms of bilirubin toxicity: Clinical implications
    • Hansen TW (2002) Mechanisms of bilirubin toxicity: clinical implications. Clin Perinatol 29(4):765-778 viii
    • (2002) Clin Perinatol , vol.29 , Issue.4
    • Hansen, T.W.1
  • 45
    • 0030613810 scopus 로고    scopus 로고
    • S100beta induces neuronal cell death through nitric oxide release from astrocytes
    • Hu J, Ferreira A, Van Eldik LJ (1997) S100beta induces neuronal cell death through nitric oxide release from astrocytes. J Neurochem 69(6):2294-2301 (Pubitemid 27495414)
    • (1997) Journal of Neurochemistry , vol.69 , Issue.6 , pp. 2294-2301
    • Hu, J.1    Ferreira, A.2    Van Eldik, L.J.3
  • 46
    • 84868553912 scopus 로고    scopus 로고
    • Inhibition of nitric oxide production and inducible nitric oxide synthase expression by a polymethoxyflavone from young fruits of Citrus unshiu in rat primary astrocytes
    • Ihara H, Yamamoto H, Ida T, Tsutsuki H, Sakamoto T, Fujita T, Okada T, Kozaki S (2012) Inhibition of nitric oxide production and inducible nitric oxide synthase expression by a polymethoxyflavone from young fruits of Citrus unshiu in rat primary astrocytes. Biosci Biotechnol Biochem 76(10):1843-1848
    • (2012) Biosci Biotechnol Biochem , vol.76 , Issue.10 , pp. 1843-1848
    • Ihara, H.1    Yamamoto, H.2    Ida, T.3    Tsutsuki, H.4    Sakamoto, T.5    Fujita, T.6    Okada, T.7    Kozaki, S.8
  • 47
    • 84855939691 scopus 로고    scopus 로고
    • A neuron-astrocyte co-culture system to investigate astrocyte-secreted factors in mouse neuronal development
    • Jones EV, Cook D, Murai KK (2012) A neuron-astrocyte co-culture system to investigate astrocyte-secreted factors in mouse neuronal development. Methods Mol Biol 814:341-352
    • (2012) Methods Mol Biol , vol.814 , pp. 341-352
    • Jones, E.V.1    Cook, D.2    Murai, K.K.3
  • 48
    • 4344689360 scopus 로고    scopus 로고
    • Understanding and preventing severe neonatal hyperbilirubinemia: Is bilirubin neurotoxity really a concern in the developed world?
    • DOI 10.1016/j.clp.2004.05.001, PII S0095510804000442
    • Kaplan M, Hammerman C (2004) Understanding and preventing severe neonatal hyperbilirubinemia: is bilirubin neurotoxity really a concern in the developed world? Clin Perinatol 31(3):555-575 (Pubitemid 39119485)
    • (2004) Clinics in Perinatology , vol.31 , Issue.3 , pp. 555-575
    • Kaplan, M.1    Hammerman, C.2
  • 49
    • 20344389247 scopus 로고    scopus 로고
    • Understanding severe hyperbilirubinemia and preventing kernicterus: Adjuncts in the interpretation of neonatal serum bilirubin
    • DOI 10.1016/j.cccn.2005.01.008, PII S0009898105000525
    • Kaplan M, Hammerman C (2005) Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin. Clin Chim Acta 356(1-2):9-21 (Pubitemid 40779883)
    • (2005) Clinica Chimica Acta , vol.356 , Issue.1-2 , pp. 9-21
    • Kaplan, M.1    Hammerman, C.2
  • 51
    • 39349116952 scopus 로고    scopus 로고
    • Opposing roles for reactive astrocytes following traumatic brain injury
    • DOI 10.1159/000111560
    • Laird MD, Vender JR, Dhandapani KM (2008) Opposing roles for reactive astrocytes following traumatic brain injury. Neurosignals 16(2-3):154-164 (Pubitemid 351263222)
    • (2008) NeuroSignals , vol.16 , Issue.2-3 , pp. 154-164
    • Laird, M.D.1    Vender, J.R.2    Dhandapani, K.M.3
  • 52
    • 0034945397 scopus 로고    scopus 로고
    • Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'
    • DOI 10.1016/S0168-8278(01)00092-7, PII S0168827801000927
    • Lazaridis KN, Gores GJ, Lindor KD (2001) Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'. J Hepatol 35(1):134-146 (Pubitemid 32646237)
    • (2001) Journal of Hepatology , vol.35 , Issue.1 , pp. 134-146
    • Lazaridis, K.N.1    Gores, G.J.2    Lindor, K.D.3
  • 53
    • 0030905262 scopus 로고    scopus 로고
    • Neuritic outgrowth associated with astroglial phenotypic changes induced by antisense glial fibrillary acidic protein (GFAP) mRNA in injured neuron- astrocyte cocultures
    • Lefrançois T, Fages C, Peschanski M, Tardy M (1997) Neuritic outgrowth associated with astroglial phenotypic changes induced by antisense glial fibrillary acidic protein (GFAP) mRNA in injured neuron-astrocyte cocultures. J Neurosci 17(11):4121-4128 (Pubitemid 27220603)
    • (1997) Journal of Neuroscience , vol.17 , Issue.11 , pp. 4121-4128
    • Lefrancois, T.1    Fages, C.2    Peschanski, M.3    Tardy, M.4
  • 55
    • 70349466534 scopus 로고    scopus 로고
    • Effects of IL-6 secreted from astrocytes on the survival of dopaminergic neurons in lipopolysaccharide-induced inflammation
    • Li XZ, Bai LM, Yang YP, Luo WF, Hu WD, Chen JP, Mao CJ, Liu CF (2009) Effects of IL-6 secreted from astrocytes on the survival of dopaminergic neurons in lipopolysaccharide-induced inflammation. Neurosci Res 65(3):252-258
    • (2009) Neurosci Res , vol.65 , Issue.3 , pp. 252-258
    • Li, X.Z.1    Bai, L.M.2    Yang, Y.P.3    Luo, W.F.4    Hu, W.D.5    Chen, J.P.6    Mao, C.J.7    Liu, C.F.8
  • 56
    • 23044460297 scopus 로고    scopus 로고
    • Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia-induced cerebellar hypoplasia in the Gunn rat
    • DOI 10.1111/j.1460-9568.2005.04182.x
    • Lin S, Wei X, Bales KR, Paul AB, Ma Z, Yan G, Paul SM, Du Y (2005) Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia- induced cerebellar hypoplasia in the Gunn rat. Eur J Neurosci 22(1):21-27 (Pubitemid 41059968)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.1 , pp. 21-27
    • Lin, S.1    Wei, X.2    Bales, K.R.3    Paul, A.B.C.4    Ma, Z.5    Yan, G.6    Paul, S.M.7    Du, Y.8
  • 57
    • 0035050120 scopus 로고    scopus 로고
    • Astrocytes contribute to neuronal impairment in bA toxicity increasing apoptosis in rat hippocampal neurons
    • DOI 10.1002/glia.1041
    • Malchiodi-Albedi F, Domenici MR, Paradisi S, Bernardo A, Ajmone-Cat MA, Minghetti L (2001) Astrocytes contribute to neuronal impairment in bA toxicity increasing apoptosis in rat hippocampal neurons. Glia 34(1):68-72 (Pubitemid 32329033)
    • (2001) GLIA , vol.34 , Issue.1 , pp. 68-72
    • Malchiodi-Albedi, F.1    Domenici, M.R.2    Paradisi, S.3    Bernardo, A.4    Ajmone-Cat, M.A.5    Minghetti, L.6
  • 58
    • 0001285005 scopus 로고
    • Bile pigments: Bilatrienes and 5,15 biladienes
    • Dolphin D (ed) Academic Press, New York
    • McDonagh AF (1979) Bile pigments: bilatrienes and 5,15 biladienes. In: Dolphin D (ed) The porphyrins. Academic Press, New York, pp 294-491
    • (1979) The Porphyrins , pp. 294-491
    • McDonagh, A.F.1
  • 59
    • 0037461753 scopus 로고    scopus 로고
    • Feeding hungry neurons: Astrocytes deliver food for thought
    • DOI 10.1016/S0896-6273(03)00027-8
    • Meeks JP, Mennerick S (2003) Feeding hungry neurons: astrocytes deliver food for thought. Neuron 37(2):187-189 (Pubitemid 36143812)
    • (2003) Neuron , vol.37 , Issue.2 , pp. 187-189
    • Meeks, J.P.1    Mennerick, S.2
  • 60
    • 0019192438 scopus 로고
    • Cerebellar hypoplasia in the Gunn rat with hereditary hyperbilirubinemia: Immunohistochemical and neurochemical studies
    • DOI 10.1111/j.1471-4159.1980.tb09003.x
    • Mikoshiba K, Kohsaka S, Takamatsu K, Tsukada Y (1980) Cerebellar hypoplasia in the Gunn rat with hereditary hyperbilirubinemia: immunohistochemical and neurochemical studies. J Neurochem 35(6):1309-1318 (Pubitemid 11172126)
    • (1980) Journal of Neurochemistry , vol.35 , Issue.6 , pp. 1309-1318
    • Mikoshiba, K.1    Kohsaka, S.2    Takamatsu, K.3    Tsukada, Y.4
  • 61
    • 78751687376 scopus 로고    scopus 로고
    • Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-kappaB reporter mice prior to loss of dopaminergic neurons
    • Miller JA, Trout BR, Sullivan KA, Bialecki RA, Roberts RA, Tjalkens RB (2011) Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-kappaB reporter mice prior to loss of dopaminergic neurons. J Neurosci Res 89(3):406-417
    • (2011) J Neurosci Res , vol.89 , Issue.3 , pp. 406-417
    • Miller, J.A.1    Trout, B.R.2    Sullivan, K.A.3    Bialecki, R.A.4    Roberts, R.A.5    Tjalkens, R.B.6
  • 62
    • 0035696282 scopus 로고    scopus 로고
    • The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease
    • DOI 10.1016/S0197-4580(01)00293-7, PII S0197458001002937
    • Mrak RE, Griffinbc WS (2001) The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease. Neurobiol Aging 22(6):915-922 (Pubitemid 34066559)
    • (2001) Neurobiology of Aging , vol.22 , Issue.6 , pp. 915-922
    • Mrak, R.E.1    Griffin, W.S.T.2
  • 63
    • 0022364119 scopus 로고
    • Cerebellar hypoplasia in the Gunn rat is associated with quantitative changes in neurotypic and gliotypic proteins
    • O'Callaghan JP, Miller DB (1985) Cerebellar hypoplasia in the Gunn rat is associated with quantitative changes in neurotypic and gliotypic proteins. J Pharmacol Exp Ther 234(2):522-533 (Pubitemid 15241877)
    • (1985) Journal of Pharmacology and Experimental Therapeutics , vol.234 , Issue.2 , pp. 522-533
    • O'Callaghan, J.P.1    Miller, D.B.2
  • 65
    • 0036234687 scopus 로고    scopus 로고
    • Mechanisms of bilirubin neurotoxicity
    • DOI 10.1053/jhep.2002.33432
    • Ostrow JD, Pascolo L, Tiribelli C (2002) Mechanisms of bilirubin neurotoxicity. Hepatology 35(5):1277-1280 (Pubitemid 34454027)
    • (2002) Hepatology , vol.35 , Issue.5 , pp. 1277-1280
    • Ostrow, J.D.1    Pascolo, L.2    Tiribelli, C.3
  • 67
    • 0025257161 scopus 로고
    • Effects of ursodeoxycholic acid and taurine on serum liver enzymes and bile acids in chronic hepatitis
    • Podda M, Ghezzi C, Battezzati PM, Crosignani A, Zuin M, Roda A (1990) Effects of ursodeoxycholic acid and taurine on serum liver enzymes and bile acids in chronic hepatitis. Gastroenterology 98(4):1044-1050 (Pubitemid 20095860)
    • (1990) Gastroenterology , vol.98 , Issue.4 , pp. 1044-1050
    • Podda, M.1    Ghezzi, C.2    Battezzati, P.M.3    Crosignani, A.4    Zuin, M.5    Roda, A.6
  • 69
    • 7444248391 scopus 로고    scopus 로고
    • The human multidrug-resistance-associated protein MRP1 mediates ATP-dependent transport of unconjugated bilirubin
    • DOI 10.1042/BJ20040599
    • Rigato I, Pascolo L, Fernetti C, Ostrow JD, Tiribelli C (2004) The human multidrug-resistance-associated protein MRP1 mediates ATP-dependent transport of unconjugated bilirubin. Biochem J 383(Pt 2):335-341 (Pubitemid 39446695)
    • (2004) Biochemical Journal , vol.383 , Issue.2 , pp. 335-341
    • Rigato, I.1    Pascolo, L.2    Fernetti, C.3    Ostrow, J.D.4    Tiribelli, C.5
  • 70
    • 77950232828 scopus 로고    scopus 로고
    • Regulation of multidrug resistance protein 1 by tumor necrosis factor a in cultured glial cells: Involvement of nuclear factor-jB and c-Jun N-terminal kinase signaling pathways
    • Ronaldson PT, Ashraf T, Bendayan R (2010) Regulation of multidrug resistance protein 1 by tumor necrosis factor a in cultured glial cells: involvement of nuclear factor-jB and c-Jun N-terminal kinase signaling pathways. Mol Pharmacol 77(4):644-659
    • (2010) Mol Pharmacol , vol.77 , Issue.4 , pp. 644-659
    • Ronaldson, P.T.1    Ashraf, T.2    Bendayan, R.3
  • 72
    • 0026717412 scopus 로고
    • Management of neonatal hyperbilirubinemia and prevention of kernicterus
    • Rubaltelli FF, Griffith PF (1992) Management of neonatal hyperbilirubinemia and prevention of kernicterus. Drugs 43(6):864-872
    • (1992) Drugs , vol.43 , Issue.6 , pp. 864-872
    • Rubaltelli, F.F.1    Griffith, P.F.2
  • 73
    • 0036997994 scopus 로고    scopus 로고
    • Intestinal absorption and biliary secretion of ursodeoxycholic acid and its taurine conjugate
    • DOI 10.1046/j.1365-2362.2002.01030.x
    • Rudolph G, Kloeters-Plachky P, Sauer P, Stiehl A (2002) Intestinal absorption and biliary secretion of ursodeoxycholic acid and its taurine conjugate. Eur J Clin Invest 32(8):575-580 (Pubitemid 36223409)
    • (2002) European Journal of Clinical Investigation , vol.32 , Issue.8 , pp. 575-580
    • Rudolph, G.1    Kloeters-Plachky, P.2    Sauer, P.3    Stiehl, A.4
  • 75
    • 0033547349 scopus 로고    scopus 로고
    • Inhibition of glutamate uptake by unconjugated bilirubin in cultured cortical rat astrocytes: Role of concentration and pH
    • Silva R, Mata LR, Gulbenkian S, Brito MA, Tiribelli C, Brites D (1999) Inhibition of glutamate uptake by unconjugated bilirubin in cultured cortical rat astrocytes: role of concentration and pH. Biochem Biophys Res Commun 265(1):67-72
    • (1999) Biochem Biophys Res Commun , vol.265 , Issue.1 , pp. 67-72
    • Silva, R.1    Mata, L.R.2    Gulbenkian, S.3    Brito, M.A.4    Tiribelli, C.5    Brites, D.6
  • 76
    • 0035072101 scopus 로고    scopus 로고
    • Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid
    • DOI 10.1016/S0168-8278(01)00015-0, PII S0168827801000150
    • Silva RFM, Rodrigues CMP, Brites D (2001) Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid. J Hepatol 34(3):402-408 (Pubitemid 32240819)
    • (2001) Journal of Hepatology , vol.34 , Issue.3 , pp. 402-408
    • Silva, R.F.M.1    Rodrigues, C.M.P.2    Brites, D.3
  • 77
    • 0036202904 scopus 로고    scopus 로고
    • Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin
    • Silva RFM, Rodrigues CMP, Brites D (2002) Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin. Pediatr Res 51(4):535-541 (Pubitemid 34267328)
    • (2002) Pediatric Research , vol.51 , Issue.4 I , pp. 535-541
    • Silva, R.F.M.1    Rodrigues, C.M.P.2    Brites, D.3
  • 79
    • 84859103402 scopus 로고    scopus 로고
    • Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10
    • Silva SL, Vaz AR, Diógenes MJ, van Rooijen N, Sebastião AM, Fernandes A, Silva RFM, Brites D (2012) Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10. Neuropharmacology 62(7):2398-2408
    • (2012) Neuropharmacology , vol.62 , Issue.7 , pp. 2398-2408
    • Silva, S.L.1    Vaz, A.R.2    Diógenes, M.J.3    Van Rooijen, N.4    Sebastião, A.M.5    Fernandes, A.6    Silva, R.F.M.7    Brites, D.8
  • 81
    • 0033230119 scopus 로고    scopus 로고
    • Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species
    • DOI 10.1002/(SICI)1098-1136(199911)28:2<85::AID-GL
    • Tanaka J, Toku K, Zhang B, Ishihara K, Sakanaka M, Maeda N (1999) Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia 28(2):85-96 (Pubitemid 29530608)
    • (1999) GLIA , vol.28 , Issue.2 , pp. 85-96
    • Tanaka, J.1    Toku, K.2    Zhang, B.3    Ishihara, K.4    Sakanaka, M.5    Maeda, N.6
  • 82
    • 84863088484 scopus 로고    scopus 로고
    • Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
    • Tian L, Ma L, Kaarela T, Li Z (2012) Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases. J Neuroinflammation 9:155
    • (2012) J Neuroinflammation , vol.9 , pp. 155
    • Tian, L.1    Ma, L.2    Kaarela, T.3    Li, Z.4
  • 83
    • 71649114447 scopus 로고    scopus 로고
    • Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: Assessment of the protective effects of glycoursodeoxycholic acid
    • Vaz AR, Delgado-Esteban M, Brito MA, Bolaños JP, Brites D, Almeida A (2010) Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid. J Neurochem 112(1):56-65
    • (2010) J Neurochem , vol.112 , Issue.1 , pp. 56-65
    • Vaz, A.R.1    Delgado-Esteban, M.2    Brito, M.A.3    Bolaños, J.P.4    Brites, D.5    Almeida, A.6
  • 85
    • 79956137679 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin
    • Vaz AR, Silva SL, Barateiro A, Fernandes A, Falcão AS, Brito MA, Brites D (2011b) Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin. Exp Neurol 229(2):381-390
    • (2011) Exp Neurol , vol.229 , Issue.2 , pp. 381-390
    • Vaz, A.R.1    Silva, S.L.2    Barateiro, A.3    Fernandes, A.4    Falcão, A.S.5    Brito, M.A.6    Brites, D.7
  • 86
    • 43249092898 scopus 로고    scopus 로고
    • Preparation and coculture of neurons and glial cells
    • Unit 2.7. doi: 10.1002/0471143030.cb0207s32
    • Viviani B (2006) Preparation and coculture of neurons and glial cells. Curr Protoc Cell Biol Chap. 2:Unit 2.7. doi: 10.1002/0471143030.cb0207s32
    • (2006) Curr Protoc Cell Biol Chap , vol.2
    • Viviani, B.1
  • 87
    • 33748750998 scopus 로고    scopus 로고
    • Dual effects of antioxidants in neurodegeneration: Direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation
    • Wang JY, Wen LL, Huang YN, Chen YT, Ku MC (2006) Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation. Curr Pharm Des 12(27):3521-3533
    • (2006) Curr Pharm des , vol.12 , Issue.27 , pp. 3521-3533
    • Wang, J.Y.1    Wen, L.L.2    Huang, Y.N.3    Chen, Y.T.4    Ku, M.C.5
  • 88
    • 21244477904 scopus 로고    scopus 로고
    • Astrocytes protect neurons from ethanol-induced oxidative stress and apoptotic death
    • DOI 10.1002/jnr.20502
    • Watts LT, Rathinam ML, Schenker S, Henderson GI (2005) Astrocytes protect neurons from ethanol-induced oxidative stress and apoptotic death. J Neurosci Res 80(5):655-666 (Pubitemid 40896186)
    • (2005) Journal of Neuroscience Research , vol.80 , Issue.5 , pp. 655-666
    • Watts, L.T.1    Rathinam, M.L.2    Schenker, S.3    Henderson, G.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.