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Volumn 39, Issue 1, 2011, Pages 115-123

Role of Astrocytes in Brain Function and Disease

Author keywords

astrocyte; nervous system; neurodegenerative diseases

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS;

EID: 79959492122     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310385254     Document Type: Article
Times cited : (194)

References (154)
  • 1
    • 10044244916 scopus 로고    scopus 로고
    • Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture
    • Abramov A. Y. Canevari L. Duchen M. R. (2004). Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture. Biochim Biophys Acta 1742, 81–87.
    • (2004) Biochim Biophys Acta , vol.1742 , pp. 81-87
    • Abramov, A.Y.1    Canevari, L.2    Duchen, M.R.3
  • 2
    • 35648954442 scopus 로고    scopus 로고
    • Astrocytes in ammonia neurotoxicity: A target, a mediator and a shield
    • Aschner, M., Costa, L. G., eds.), pp., CRC Press, Boca Raton, FL
    • Albrecht J. (2005). Astrocytes in ammonia neurotoxicity: A target, a mediator and a shield. In The Role of Glia in Neurotoxicity (Aschner M. Costa L. G. eds.), pp. 329–42. CRC Press, Boca Raton, FL.
    • (2005) The Role of Glia in Neurotoxicity , pp. 329-342
    • Albrecht, J.1
  • 3
    • 33750608704 scopus 로고    scopus 로고
    • Glutamine: A Trojan horse in ammonia neurotoxicity
    • Albrecht J. Norenberg M. D. (2006). Glutamine: A Trojan horse in ammonia neurotoxicity. Hepatology 44, 788–94.
    • (2006) Hepatology , vol.44 , pp. 788-794
    • Albrecht, J.1    Norenberg, M.D.2
  • 4
    • 77749336627 scopus 로고    scopus 로고
    • Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: Impact on neuronal viability
    • Allaman I. Gavillet M. Belanger M. Laroche T. Viertl D. Lashuel H. A. Magistretti P. J. (2010). Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: Impact on neuronal viability. J Neurosci 30, 3326–38.
    • (2010) J Neurosci , vol.30 , pp. 3326-3338
    • Allaman, I.1    Gavillet, M.2    Belanger, M.3    Laroche, T.4    Viertl, D.5    Lashuel, H.A.6    Magistretti, P.J.7
  • 6
    • 84992902713 scopus 로고    scopus 로고
    • Neurotoxic injury and astrocytes
    • de Vellis, J., Ed.), pp., Totowa, NJ, Humana
    • Aschner M. LoPachin R. M. (2001). Neurotoxic injury and astrocytes. In Neuroglia in the Aging Brain (de Vellis J. Ed.), pp. 259–74. Totowa, NJ: Humana.
    • (2001) Neuroglia in the Aging Brain , pp. 259-274
    • Aschner, M.1    LoPachin, R.M.2
  • 7
  • 9
    • 38349119105 scopus 로고    scopus 로고
    • 13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix
    • Bak L. K. Zieminska E. Waagepetersen H. S. Schousboe A. Albrecht J. (2008). Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix. Neurochem Res 33, 273–78.
    • (2008) Neurochem Res , vol.33 , pp. 273-278
    • Bak, L.K.1    Zieminska, E.2    Waagepetersen, H.S.3    Schousboe, A.4    Albrecht, J.5
  • 10
    • 0021696793 scopus 로고
    • Toxins in hepatic encephalopathy: The role of the synergistic effect of ammonia, mercaptans and short chain fatty acids
    • Baraldi M. Pinelli G. Ricci P. Zeneroli M. L. (1984). Toxins in hepatic encephalopathy: The role of the synergistic effect of ammonia, mercaptans and short chain fatty acids. Arch Toxicol Suppl 7, 103–5.
    • (1984) Arch Toxicol Suppl , vol.7 , pp. 103-105
    • Baraldi, M.1    Pinelli, G.2    Ricci, P.3    Zeneroli, M.L.4
  • 11
    • 84982337275 scopus 로고
    • Amino acid and protein metabolism of the brain—VI. Cerebral compartments of glutamic acid metabolism
    • Berl S. Lajtha A. Waelsch H. (1961). Amino acid and protein metabolism of the brain—VI. Cerebral compartments of glutamic acid metabolism. J Neurochem 7, 322–32.
    • (1961) J Neurochem , vol.7 , pp. 322-332
    • Berl, S.1    Lajtha, A.2    Waelsch, H.3
  • 12
    • 84989509425 scopus 로고
    • Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis
    • Blei A. T. Olafsson S. Therrien G. Butterworth R. F. (1994). Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis. Hepatology 19, 1437–44.
    • (1994) Hepatology , vol.19 , pp. 1437-1444
    • Blei, A.T.1    Olafsson, S.2    Therrien, G.3    Butterworth, R.F.4
  • 13
    • 0025810944 scopus 로고
    • The role of methanethiol in the pathogenesis of hepatic encephalopathy
    • Blom H. J. Ferenci P. Grimm G. Yap S. H. Tangerman A. (1991). The role of methanethiol in the pathogenesis of hepatic encephalopathy. Hepatology 13, 445–54.
    • (1991) Hepatology , vol.13 , pp. 445-454
    • Blom, H.J.1    Ferenci, P.2    Grimm, G.3    Yap, S.H.4    Tangerman, A.5
  • 14
    • 0032174031 scopus 로고    scopus 로고
    • Calcium tsunamis: Do astrocytes transmit cell death messages via gap junctions during ischemia?
    • Budd S. L. Lipton S. A. (1998). Calcium tsunamis: Do astrocytes transmit cell death messages via gap junctions during ischemia? Nat Neurosci 1, 431–32.
    • (1998) Nat Neurosci , vol.1 , pp. 431-432
    • Budd, S.L.1    Lipton, S.A.2
  • 15
    • 0036988606 scopus 로고    scopus 로고
    • Pathophysiology of hepatic encephalopathy: A new look at ammonia
    • Butterworth R. F. (2002). Pathophysiology of hepatic encephalopathy: A new look at ammonia. Metab Brain Dis 17, 221–27.
    • (2002) Metab Brain Dis , vol.17 , pp. 221-227
    • Butterworth, R.F.1
  • 16
    • 35448969806 scopus 로고    scopus 로고
    • Neuronal cell death in hepatic encephalopathy
    • Butterworth R. F. (2007). Neuronal cell death in hepatic encephalopathy. Metab Brain Dis 22, 309–20.
    • (2007) Metab Brain Dis , vol.22 , pp. 309-320
    • Butterworth, R.F.1
  • 17
    • 1542377619 scopus 로고    scopus 로고
    • Toxicity of amyloid beta peptide: Tales of calcium, mitochondria, and oxidative stress
    • Canevari L. Abramov A. Y. Duchen M. R. (2004). Toxicity of amyloid beta peptide: Tales of calcium, mitochondria, and oxidative stress. Neurochem Res 29, 637–50.
    • (2004) Neurochem Res , vol.29 , pp. 637-650
    • Canevari, L.1    Abramov, A.Y.2    Duchen, M.R.3
  • 18
    • 0022907958 scopus 로고
    • Cytochemical identification of cerebral glycogen and glucose-6-phosphatase activity under normal and experimental conditions. II. Choroid plexus and ependymal epithelia, endothelia and pericytes
    • Cataldo A. M. Broadwell R. D. (1986). Cytochemical identification of cerebral glycogen and glucose-6-phosphatase activity under normal and experimental conditions. II. Choroid plexus and ependymal epithelia, endothelia and pericytes. J Neurocytol 15, 511–24.
    • (1986) J Neurocytol , vol.15 , pp. 511-524
    • Cataldo, A.M.1    Broadwell, R.D.2
  • 19
    • 0028966538 scopus 로고
    • Immunocytochemical examination of neural rat and mouse primary cultures using monoclonal antibodies raised against pyruvate carboxylase
    • Cesar M. Hamprecht B. (1995). Immunocytochemical examination of neural rat and mouse primary cultures using monoclonal antibodies raised against pyruvate carboxylase. J Neurochem 64, 2312–18.
    • (1995) J Neurochem , vol.64 , pp. 2312-2318
    • Cesar, M.1    Hamprecht, B.2
  • 20
    • 62449132771 scopus 로고    scopus 로고
    • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson’s disease: Critical role for the astrocyte
    • Chen P. C. Vargas M. R. Pani A. K. Smeyne R. J. Johnson D. A. Kan Y. W. Johnson J. A. (2009). Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson’s disease: Critical role for the astrocyte. Proc Natl Acad Sci U S A 106, 2933–38.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2933-2938
    • Chen, P.C.1    Vargas, M.R.2    Pani, A.K.3    Smeyne, R.J.4    Johnson, D.A.5    Kan, Y.W.6    Johnson, J.A.7
  • 21
    • 33845296450 scopus 로고    scopus 로고
    • Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes
    • Chen P. S. Peng G. S. Li G. Yang S. Wu X. Wang C. C. Wilson B. Lu R. B. Gean P. W. Chuang D. M. Hong J. S. (2006). Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes. Mol Psychiatry 11, 1116–25.
    • (2006) Mol Psychiatry , vol.11 , pp. 1116-1125
    • Chen, P.S.1    Peng, G.S.2    Li, G.3    Yang, S.4    Wu, X.5    Wang, C.C.6    Wilson, B.7    Lu, R.B.8    Gean, P.W.9    Chuang, D.M.10    Hong, J.S.11
  • 23
    • 0002206947 scopus 로고
    • The hepatic encephalopathies
    • Conn, H. O., Bircher, J., eds.), pp., Medi-Ed Press, Bloomington, IN
    • Conn H. O. (1994). The hepatic encephalopathies. In Hepatic Encephalopathy: Syndromes and Therapies (Conn H. O. Bircher J. eds.), pp. 1–12. Medi-Ed Press, Bloomington, IN.
    • (1994) Hepatic Encephalopathy: Syndromes and Therapies , pp. 1-12
    • Conn, H.O.1
  • 25
    • 0026633956 scopus 로고
    • Free radical scavenging systems of rat astroglial cells in primary culture: Effects of anoxia and drug treatment
    • Copin J. C. Ledig M. Tholey G. (1992). Free radical scavenging systems of rat astroglial cells in primary culture: Effects of anoxia and drug treatment. Neurochem Res 17, 677–82.
    • (1992) Neurochem Res , vol.17 , pp. 677-682
    • Copin, J.C.1    Ledig, M.2    Tholey, G.3
  • 26
    • 0032970942 scopus 로고    scopus 로고
    • Mild hypothermia modifies ammonia-induced brain edema in rats after portacaval anastomosis
    • Cordoba J. Crespin J. Gottstein J. Blei A. T. (1999). Mild hypothermia modifies ammonia-induced brain edema in rats after portacaval anastomosis. Gastroenterology 116, 686–93.
    • (1999) Gastroenterology , vol.116 , pp. 686-693
    • Cordoba, J.1    Crespin, J.2    Gottstein, J.3    Blei, A.T.4
  • 27
    • 0029827933 scopus 로고    scopus 로고
    • Glutamine, myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat: Implications for ammonia-induced brain edema
    • Cordoba J. Gottstein J. Blei A. T. (1996). Glutamine, myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat: Implications for ammonia-induced brain edema. Hepatology 24, 919–23.
    • (1996) Hepatology , vol.24 , pp. 919-923
    • Cordoba, J.1    Gottstein, J.2    Blei, A.T.3
  • 30
    • 18144453796 scopus 로고    scopus 로고
    • Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer’s disease
    • DeWitt D. A. Perry G. Cohen M. Doller C. Silver J. (1998). Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer’s disease. Exp Neurol 149, 329–40.
    • (1998) Exp Neurol , vol.149 , pp. 329-340
    • DeWitt, D.A.1    Perry, G.2    Cohen, M.3    Doller, C.4    Silver, J.5
  • 31
    • 0024449603 scopus 로고
    • Functional changes of brain mitochondria during experimental hepatic encephalopathy
    • Diaz-Munoz M. Tapia R. (1989). Functional changes of brain mitochondria during experimental hepatic encephalopathy. Biochem Pharmacol 38, 3835–41.
    • (1989) Biochem Pharmacol , vol.38 , pp. 3835-3841
    • Diaz-Munoz, M.1    Tapia, R.2
  • 32
    • 0030602843 scopus 로고    scopus 로고
    • Ammonia stimulates glutamine uptake to the cerebral non-synaptic mitochondria of the rat
    • Dolinska M. Hilgier W. Albrecht J. (1996). Ammonia stimulates glutamine uptake to the cerebral non-synaptic mitochondria of the rat. Neurosci Lett 213, 45–48.
    • (1996) Neurosci Lett , vol.213 , pp. 45-48
    • Dolinska, M.1    Hilgier, W.2    Albrecht, J.3
  • 33
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain
    • Dringen R. (2000). Metabolism and functions of glutathione in brain. Prog Neurobiol 62, 649–71.
    • (2000) Prog Neurobiol , vol.62 , pp. 649-671
    • Dringen, R.1
  • 34
    • 0038636003 scopus 로고    scopus 로고
    • Glutathione pathways in the brain
    • Dringen R. Hirrlinger J. (2003). Glutathione pathways in the brain. Biol Chem 384, 505–16.
    • (2003) Biol Chem , vol.384 , pp. 505-516
    • Dringen, R.1    Hirrlinger, J.2
  • 35
    • 0033555806 scopus 로고    scopus 로고
    • Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione
    • Dringen R. Pfeiffer B. Hamprecht B. (1999). Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci 19, 562–69.
    • (1999) J Neurosci , vol.19 , pp. 562-569
    • Dringen, R.1    Pfeiffer, B.2    Hamprecht, B.3
  • 36
    • 0026350138 scopus 로고
    • Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: Effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy
    • Faff-Michalak L. Albrecht J. (1991). Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: Effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy. Metab Brain Dis 6, 187–97.
    • (1991) Metab Brain Dis , vol.6 , pp. 187-197
    • Faff-Michalak, L.1    Albrecht, J.2
  • 37
    • 0027456926 scopus 로고
    • The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: Comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy
    • Faff-Michalak L. Albrecht J. (1993). The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: Comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy. Neurochem Res 18, 119–23.
    • (1993) Neurochem Res , vol.18 , pp. 119-123
    • Faff-Michalak, L.1    Albrecht, J.2
  • 38
    • 0033180342 scopus 로고    scopus 로고
    • The glial scar and central nervous system repair
    • Fawcett J. W. Asher R. A. (1999). The glial scar and central nervous system repair. Brain Res Bull 49, 377–91.
    • (1999) Brain Res Bull , vol.49 , pp. 377-391
    • Fawcett, J.W.1    Asher, R.A.2
  • 39
    • 0036191173 scopus 로고    scopus 로고
    • Hepatic encephalopathy—definition, nomenclature, diagnosis, and quantification: Final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998
    • Ferenci P. Lockwood A. Mullen K. Tarter R. Weissenborn K. Blei A. T. (2002). Hepatic encephalopathy—definition, nomenclature, diagnosis, and quantification: Final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 35, 716–21.
    • (2002) Hepatology , vol.35 , pp. 716-721
    • Ferenci, P.1    Lockwood, A.2    Mullen, K.3    Tarter, R.4    Weissenborn, K.5    Blei, A.T.6
  • 40
    • 0030840881 scopus 로고    scopus 로고
    • High affinity glutamate transporters: Regulation of expression and activity
    • Gegelashvili G. Schousboe A. (1997). High affinity glutamate transporters: Regulation of expression and activity. Mol Pharmacol 52, 6–15.
    • (1997) Mol Pharmacol , vol.52 , pp. 6-15
    • Gegelashvili, G.1    Schousboe, A.2
  • 41
    • 0032006244 scopus 로고    scopus 로고
    • Cellular distribution and kinetic properties of high-affinity glutamate transporters
    • Gegelashvili G. Schousboe A. (1998). Cellular distribution and kinetic properties of high-affinity glutamate transporters. Brain Res Bull 45, 233–38.
    • (1998) Brain Res Bull , vol.45 , pp. 233-238
    • Gegelashvili, G.1    Schousboe, A.2
  • 42
    • 77951077317 scopus 로고    scopus 로고
    • Astrocytic expression of Parkinson’s disease-related A53T alpha-synuclein causes neurodegeneration in mice
    • Gu X. L. Long C. X. Sun L. Xie C. Lin X. Cai H. (2010). Astrocytic expression of Parkinson’s disease-related A53T alpha-synuclein causes neurodegeneration in mice. Mol Brain 21, 3–12.
    • (2010) Mol Brain , vol.21 , pp. 3-12
    • Gu, X.L.1    Long, C.X.2    Sun, L.3    Xie, C.4    Lin, X.5    Cai, H.6
  • 43
    • 0027333557 scopus 로고
    • Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide
    • Haass C. Selkoe D. J. (1993). Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell 75, 1039–42.
    • (1993) Cell , vol.75 , pp. 1039-1042
    • Haass, C.1    Selkoe, D.J.2
  • 44
    • 0035213016 scopus 로고    scopus 로고
    • Differences in neurotransmitter synthesis and intermediary metabolism between glutamatergic and GABAergic neurons during 4 hours of middle cerebral artery occlusion in the rat: The role of astrocytes in neuronal survival
    • Haberg A. Qu H. Saether O. Unsgard G. Haraldseth O. Sonnewald U. (2001). Differences in neurotransmitter synthesis and intermediary metabolism between glutamatergic and GABAergic neurons during 4 hours of middle cerebral artery occlusion in the rat: The role of astrocytes in neuronal survival. J Cereb Blood Flow Metab 21, 1451–63.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1451-1463
    • Haberg, A.1    Qu, H.2    Saether, O.3    Unsgard, G.4    Haraldseth, O.5    Sonnewald, U.6
  • 45
    • 0026432652 scopus 로고
    • Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure
    • Harrison P. M. Wendon J. A. Gimson A. E. Alexander G. J. Williams R. (1991). Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure. N Engl J Med 324, 1852–57.
    • (1991) N Engl J Med , vol.324 , pp. 1852-1857
    • Harrison, P.M.1    Wendon, J.A.2    Gimson, A.E.3    Alexander, G.J.4    Williams, R.5
  • 46
    • 0027474144 scopus 로고
    • Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy
    • Hawkins R. A. Jessy J. Mans A. M. De Joseph M. R. (1993). Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy. J Neurochem 60, 1000–1006.
    • (1993) J Neurochem , vol.60 , pp. 1000-1006
    • Hawkins, R.A.1    Jessy, J.2    Mans, A.M.3    De Joseph, M.R.4
  • 47
    • 0024381035 scopus 로고
    • Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse
    • Heikkila R. E. Sieber B. A. Manzino L. Sonsalla P. K. (1989). Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. Mol Chem Neuropathol 10, 171–83.
    • (1989) Mol Chem Neuropathol , vol.10 , pp. 171-183
    • Heikkila, R.E.1    Sieber, B.A.2    Manzino, L.3    Sonsalla, P.K.4
  • 48
    • 0002591234 scopus 로고
    • Neuronal–astrocytic interactions in metabolism of transmitter amino acids of the glutamate family
    • Schousboe, A., Diemer, N. H., Kofod, H., eds.), pp., Copenhagen, Denmark, Munksgaard
    • Hertz L. Peng L. Westergaard N. Yudkoff M. Schousboe A. (1992). Neuronal–astrocytic interactions in metabolism of transmitter amino acids of the glutamate family. In Alfred Benzon Symposium 32, Drug Research Related to Neuroactive Amino Acids (Schousboe A. Diemer N. H. Kofod H. eds.), pp. 30–48. Copenhagen, Denmark: Munksgaard.
    • (1992) Alfred Benzon Symposium 32, Drug Research Related to Neuroactive Amino Acids , pp. 30-48
    • Hertz, L.1    Peng, L.2    Westergaard, N.3    Yudkoff, M.4    Schousboe, A.5
  • 49
    • 0038066410 scopus 로고    scopus 로고
    • Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum
    • Hilgier W. Anderzhanova E. Oja S. S. Saransaari P. Albrecht J. (2003). Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum. Eur J Pharmacol 468, 21–25.
    • (2003) Eur J Pharmacol , vol.468 , pp. 21-25
    • Hilgier, W.1    Anderzhanova, E.2    Oja, S.S.3    Saransaari, P.4    Albrecht, J.5
  • 50
    • 38349161319 scopus 로고    scopus 로고
    • Effect of glutamine synthesis inhibition with methionine sulfoximine on the nitric oxide-cyclic GMP pathway in the rat striatum treated acutely with ammonia: A microdialysis study
    • Hilgier W. Wegrzynowicz M. Maczewski M. Beresewicz A. Oja S. S. Saransaari P. Albrecht J. (2008). Effect of glutamine synthesis inhibition with methionine sulfoximine on the nitric oxide-cyclic GMP pathway in the rat striatum treated acutely with ammonia: A microdialysis study. Neurochem Res 33, 267–72.
    • (2008) Neurochem Res , vol.33 , pp. 267-272
    • Hilgier, W.1    Wegrzynowicz, M.2    Maczewski, M.3    Beresewicz, A.4    Oja, S.S.5    Saransaari, P.6    Albrecht, J.7
  • 51
    • 0017362424 scopus 로고
    • Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts
    • Hindfelt B. Plum F. Duffy T. E. (1977). Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts. J Clin Invest 59, 386–96.
    • (1977) J Clin Invest , vol.59 , pp. 386-396
    • Hindfelt, B.1    Plum, F.2    Duffy, T.E.3
  • 53
    • 0023263919 scopus 로고
    • Biochemical pathophysiology of Parkinson’s disease
    • Hornykiewicz O. Kish S. J. (1987). Biochemical pathophysiology of Parkinson’s disease. Adv Neurol 45, 19–34.
    • (1987) Adv Neurol , vol.45 , pp. 19-34
    • Hornykiewicz, O.1    Kish, S.J.2
  • 54
    • 33644898880 scopus 로고    scopus 로고
    • Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: Astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase
    • Ishida Y. Nagai A. Kobayashi S. Kim S. U. (2006). Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: Astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase. J Neuropathol Exp Neurol 65, 66–77.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 66-77
    • Ishida, Y.1    Nagai, A.2    Kobayashi, S.3    Kim, S.U.4
  • 55
    • 0032973861 scopus 로고    scopus 로고
    • Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis
    • Iwata-Ichikawa E. Kondo Y. Miyazaki I. Asanuma M. Ogawa N. (1999). Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis. J Neurochem 72, 2334–44.
    • (1999) J Neurochem , vol.72 , pp. 2334-2344
    • Iwata-Ichikawa, E.1    Kondo, Y.2    Miyazaki, I.3    Asanuma, M.4    Ogawa, N.5
  • 56
    • 2542491081 scopus 로고    scopus 로고
    • Glutamine-induced free radical production in cultured astrocytes
    • Jayakumar A. R. Rama Rao K. V. Schousboe A. Norenberg M. D. (2004). Glutamine-induced free radical production in cultured astrocytes. Glia 46, 296–301.
    • (2004) Glia , vol.46 , pp. 296-301
    • Jayakumar, A.R.1    Rama Rao, K.V.2    Schousboe, A.3    Norenberg, M.D.4
  • 57
    • 33645851362 scopus 로고    scopus 로고
    • Glutamine in the mechanism of ammonia-induced astrocyte swelling
    • Jayakumar A. R. Rao K. V. Murthy Ch R. Norenberg M. D. (2006). Glutamine in the mechanism of ammonia-induced astrocyte swelling. Neurochem Int 48, 623–28.
    • (2006) Neurochem Int , vol.48 , pp. 623-628
    • Jayakumar, A.R.1    Rao, K.V.2    Murthy Ch, R.3    Norenberg, M.D.4
  • 58
    • 69549088149 scopus 로고    scopus 로고
    • Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats
    • Jiang W. Desjardins P. Butterworth R. F. (2009). Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats. Neurochem Int 55, 601–5.
    • (2009) Neurochem Int , vol.55 , pp. 601-605
    • Jiang, W.1    Desjardins, P.2    Butterworth, R.F.3
  • 59
    • 0032891616 scopus 로고    scopus 로고
    • A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced
    • Johnstone M. Gearing A. J. Miller K. M. (1999). A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced. J Neuroimmunol 93, 182–93.
    • (1999) J Neuroimmunol , vol.93 , pp. 182-193
    • Johnstone, M.1    Gearing, A.J.2    Miller, K.M.3
  • 60
    • 0031902252 scopus 로고    scopus 로고
    • Mechanism of action and value of N-acetylcysteine in the treatment of early and late acetaminophen poisoning: A critical review
    • Jones A. L. (1998). Mechanism of action and value of N-acetylcysteine in the treatment of early and late acetaminophen poisoning: A critical review. J Toxicol Clin Toxicol 36, 277–85.
    • (1998) J Toxicol Clin Toxicol , vol.36 , pp. 277-285
    • Jones, A.L.1
  • 61
    • 33846249322 scopus 로고    scopus 로고
    • Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress
    • Kaur P. Aschner M. Syversen T. (2007). Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress. Toxicology 230, 164–77.
    • (2007) Toxicology , vol.230 , pp. 164-177
    • Kaur, P.1    Aschner, M.2    Syversen, T.3
  • 62
    • 77949546914 scopus 로고    scopus 로고
    • Functions of mature mammalian astrocytes: A current view
    • Kimelberg H. K. (2010). Functions of mature mammalian astrocytes: A current view. Neuroscientist 16, 79–106.
    • (2010) Neuroscientist , vol.16 , pp. 79-106
    • Kimelberg, H.K.1
  • 65
    • 0030901009 scopus 로고    scopus 로고
    • Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria
    • Kosenko E. Felipo V. Montoliu C. Grisolía S. Kaminsky Y. (1996). Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. Metab Brain Dis 12, 69–82.
    • (1996) Metab Brain Dis , vol.12 , pp. 69-82
    • Kosenko, E.1    Felipo, V.2    Montoliu, C.3    Grisolía, S.4    Kaminsky, Y.5
  • 66
    • 0027988722 scopus 로고
    • Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and Na+,K(+)-ATPase
    • Kosenko E. Kaminsky Y. Grau E. Minana M. D. Marcaida G. Grisolia S. Felipo V. (1994). Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and Na+,K(+)-ATPase. J Neurochem 63, 2172–78.
    • (1994) J Neurochem , vol.63 , pp. 2172-2178
    • Kosenko, E.1    Kaminsky, Y.2    Grau, E.3    Minana, M.D.4    Marcaida, G.5    Grisolia, S.6    Felipo, V.7
  • 68
    • 0032840954 scopus 로고    scopus 로고
    • beta-Amyloid immunoreactivity in astrocytes in Alzheimer’s disease brain biopsies: An electron microscope study
    • Kurt M. A. Davies D. C. Kidd M. (1999). beta-Amyloid immunoreactivity in astrocytes in Alzheimer’s disease brain biopsies: An electron microscope study. Exp Neurol 158, 221–28.
    • (1999) Exp Neurol , vol.158 , pp. 221-228
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3
  • 69
    • 0141485079 scopus 로고
    • Amino acid and protein metabolism of the brain. IV. The metabolism of glutamic acid
    • Lajtha A. Berl S. Waelsch H. (1959). Amino acid and protein metabolism of the brain. IV. The metabolism of glutamic acid. J Neurochem 3, 322–32.
    • (1959) J Neurochem , vol.3 , pp. 322-332
    • Lajtha, A.1    Berl, S.2    Waelsch, H.3
  • 70
    • 0032497504 scopus 로고    scopus 로고
    • Parkinson’s disease. First of two parts
    • Lang A. E. Lozano A. M. (1998). Parkinson’s disease. First of two parts. N Engl J Med 339, 1044–53.
    • (1998) N Engl J Med , vol.339 , pp. 1044-1053
    • Lang, A.E.1    Lozano, A.M.2
  • 71
    • 0029851902 scopus 로고    scopus 로고
    • Is glia disfunction the initial cause of neuronal death in ischemic penumbra?
    • Largo C. Cuevas P. Herreras O. (1996). Is glia disfunction the initial cause of neuronal death in ischemic penumbra? Neurol Res 18, 445–48.
    • (1996) Neurol Res , vol.18 , pp. 445-448
    • Largo, C.1    Cuevas, P.2    Herreras, O.3
  • 72
    • 0030892658 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis
    • Laubenberger J. Haussinger D. Bayer S. Gufler H. Hennig J. Langer M. (1997). Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis. Gastroenterology 112, 1610–16.
    • (1997) Gastroenterology , vol.112 , pp. 1610-1616
    • Laubenberger, J.1    Haussinger, D.2    Bayer, S.3    Gufler, H.4    Hennig, J.5    Langer, M.6
  • 73
    • 0023176895 scopus 로고
    • Amino acid changes in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy
    • Lavoie J. Giguere J. F. Layrargues G. P. Butterworth R. F. (1987). Amino acid changes in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy. J Neurochem 49, 692–97.
    • (1987) J Neurochem , vol.49 , pp. 692-697
    • Lavoie, J.1    Giguere, J.F.2    Layrargues, G.P.3    Butterworth, R.F.4
  • 75
    • 0028958939 scopus 로고
    • Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations
    • Lehre K. P. Levy L. M. Ottersen O. P. Storm-Mathisen J. Danbolt N. C. (1995). Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations. J Neurosci 15, 1835–53.
    • (1995) J Neurosci , vol.15 , pp. 1835-1853
    • Lehre, K.P.1    Levy, L.M.2    Ottersen, O.P.3    Storm-Mathisen, J.4    Danbolt, N.C.5
  • 77
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin L. F. Doherty D. H. Lile J. D. Bektesh S. Collins F. (1993). GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130–32.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 79
    • 0027976087 scopus 로고
    • Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: Evidence that astrocytes play an important role in antioxidative processes in the brain
    • Makar T. K. Nedergaard M. Preuss A. Gelbard A. S. Perumal A. S. Cooper A. J. (1994). Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: Evidence that astrocytes play an important role in antioxidative processes in the brain. J Neurochem 62, 45–53.
    • (1994) J Neurochem , vol.62 , pp. 45-53
    • Makar, T.K.1    Nedergaard, M.2    Preuss, A.3    Gelbard, A.S.4    Perumal, A.S.5    Cooper, A.J.6
  • 80
    • 0026487634 scopus 로고
    • Synthesis and release of neuroactive substances by glial cells
    • Martin D. L. (1992). Synthesis and release of neuroactive substances by glial cells. Glia 5, 81–94.
    • (1992) Glia , vol.5 , pp. 81-94
    • Martin, D.L.1
  • 81
    • 0017579832 scopus 로고
    • Glutamine synthetase: Glial localization in brain
    • Martinez-Hernandez A. Bell K. P. Norenberg M. D. (1977). Glutamine synthetase: Glial localization in brain. Science 195, 1356–58.
    • (1977) Science , vol.195 , pp. 1356-1358
    • Martinez-Hernandez, A.1    Bell, K.P.2    Norenberg, M.D.3
  • 82
    • 53949085542 scopus 로고    scopus 로고
    • Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades
    • Matos M. Augusto E. Oliveira C. R. Agostinho P. (2008). Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades. Neuroscience 156, 898–910.
    • (2008) Neuroscience , vol.156 , pp. 898-910
    • Matos, M.1    Augusto, E.2    Oliveira, C.R.3    Agostinho, P.4
  • 84
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease
    • McKhann G. Drachman D. Folstein M. Katzman R. Price D. Stadlan E. M. (1984). Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 34, 939–44.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 85
    • 0032738677 scopus 로고    scopus 로고
    • The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease
    • Mirza B. Hadberg H. Thomsen P. Moos T. (2000). The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease. Neuroscience 95, 425–32.
    • (2000) Neuroscience , vol.95 , pp. 425-432
    • Mirza, B.1    Hadberg, H.2    Thomsen, P.3    Moos, T.4
  • 86
    • 0035094378 scopus 로고    scopus 로고
    • Manganese elevations in blood of children with congenital portosystemic shunts
    • Mizoguchi N. Nishimura Y. Ono H. Sakura N. (2001). Manganese elevations in blood of children with congenital portosystemic shunts. Eur J Pediatr 160, 247–50.
    • (2001) Eur J Pediatr , vol.160 , pp. 247-250
    • Mizoguchi, N.1    Nishimura, Y.2    Ono, H.3    Sakura, N.4
  • 87
    • 0026555334 scopus 로고
    • Depletion of brain glutathione by buthionine sulfoximine enhances cerebral ischemic injury in rats
    • Mizui T. Kinouchi H. Chan P. H. (1992). Depletion of brain glutathione by buthionine sulfoximine enhances cerebral ischemic injury in rats. Am J Physiol 262, H313–17.
    • (1992) Am J Physiol , vol.262 , pp. H313-H317
    • Mizui, T.1    Kinouchi, H.2    Chan, P.H.3
  • 88
    • 0035830737 scopus 로고    scopus 로고
    • Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat
    • Montes S. Alcaraz-Zubeldia M. Muriel P. Rios C. (2001). Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat. Brain Res 891, 123–29.
    • (2001) Brain Res , vol.891 , pp. 123-129
    • Montes, S.1    Alcaraz-Zubeldia, M.2    Muriel, P.3    Rios, C.4
  • 90
    • 33846409008 scopus 로고    scopus 로고
    • Review of the final report of the 1998 Working Party on Definition, Nomenclature and Diagnosis of Hepatic Encephalopathy
    • Mullen K. D. (2007). Review of the final report of the 1998 Working Party on Definition, Nomenclature and Diagnosis of Hepatic Encephalopathy. Aliment Pharmacol Ther 25 (Suppl. 1), 11–16.
    • (2007) Aliment Pharmacol Ther , pp. 11-16
    • Mullen, K.D.1
  • 91
    • 0035888288 scopus 로고    scopus 로고
    • Ammonia-induced production of free radicals in primary cultures of rat astrocytes
    • Murthy C. R. Rama Rao K. V. Bai G. Norenberg M. D. (2001). Ammonia-induced production of free radicals in primary cultures of rat astrocytes. J Neurosci Res 66, 282–88.
    • (2001) J Neurosci Res , vol.66 , pp. 282-288
    • Murthy, C.R.1    Rama Rao, K.V.2    Bai, G.3    Norenberg, M.D.4
  • 92
    • 0037427384 scopus 로고    scopus 로고
    • Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
    • Nagele R. G. D’Andrea M. R. Lee H. Venkataraman V. Wang H. Y. (2003). Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains. Brain Res 971, 197–209.
    • (2003) Brain Res , vol.971 , pp. 197-209
    • Nagele, R.G.1    D’Andrea, M.R.2    Lee, H.3    Venkataraman, V.4    Wang, H.Y.5
  • 93
    • 2442707974 scopus 로고    scopus 로고
    • Increased apoptosis and inflammation after focal brain ischemia in mice lacking connexin43 in astrocytes
    • Nakase T. Sohl G. Theis M. Willecke K. Naus C. C. G. (2004). Increased apoptosis and inflammation after focal brain ischemia in mice lacking connexin43 in astrocytes. American J Pathol 164, 2067–75
    • (2004) American J Pathol , vol.64 , pp. 2067-2075
    • Nakase, T.1    Sohl, G.2    Theis, M.3    Willecke, K.4    Naus, C.C.G.5
  • 94
    • 76949089544 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction and oxidative damage in Parkinson’s disease
    • Navarro A. Boveris A. (2009). Brain mitochondrial dysfunction and oxidative damage in Parkinson’s disease. J Bioenerg Biomembr 41, 517–21.
    • (2009) J Bioenerg Biomembr , vol.41 , pp. 517-521
    • Navarro, A.1    Boveris, A.2
  • 95
    • 0017735996 scopus 로고
    • A light and electron microscopic study of experimental portal-systemic (ammonia) encephalopathy. Progression and reversal of the disorder
    • Norenberg M. D. (1977). A light and electron microscopic study of experimental portal-systemic (ammonia) encephalopathy. Progression and reversal of the disorder. Lab Invest 36, 618–27.
    • (1977) Lab Invest , vol.36 , pp. 618-627
    • Norenberg, M.D.1
  • 96
    • 0000977706 scopus 로고
    • The astrocyte in liver disease
    • Fedoroff, S., Hertz, L., eds.), pp., San Diego, CA, Academic Press
    • Norenberg M. D. (1981). The astrocyte in liver disease. In Advances in Cellular Neurobiology 2 (Fedoroff S. Hertz L. eds.), pp. 303–52. San Diego, CA: Academic Press.
    • (1981) Advances in Cellular Neurobiology 2 , pp. 303-352
    • Norenberg, M.D.1
  • 97
    • 0023287036 scopus 로고
    • The role of astrocytes in hepatic encephalopathy
    • Norenberg M. D. (1987). The role of astrocytes in hepatic encephalopathy. Neurochem Pathol 6, 13–33.
    • (1987) Neurochem Pathol , vol.6 , pp. 13-33
    • Norenberg, M.D.1
  • 98
    • 0028321104 scopus 로고
    • Astrocyte swelling in liver failure: Role of glutamine and benzodiazepines
    • Norenberg M. D. Bender A. S. (1994). Astrocyte swelling in liver failure: Role of glutamine and benzodiazepines. Acta Neurochir Suppl (Wien) 60, 24–27.
    • (1994) Acta Neurochir Suppl (Wien) , vol.60 , pp. 24-27
    • Norenberg, M.D.1    Bender, A.S.2
  • 99
    • 77952573750 scopus 로고    scopus 로고
    • Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer’s disease
    • Olabarria M. Noristani H. N. Verkhratsky A. Rodríguez J. J. (2010). Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer’s disease. Glia 58, 831–38.
    • (2010) Glia , vol.58 , pp. 831-838
    • Olabarria, M.1    Noristani, H.N.2    Verkhratsky, A.3    Rodríguez, J.J.4
  • 100
    • 0028917511 scopus 로고
    • Brain edema and intracranial hypertension in rats after total hepatectomy
    • Olafsson S. Gottstein J. Blei A. T. (1995). Brain edema and intracranial hypertension in rats after total hepatectomy. Gastroenterology 108, 1097–1103.
    • (1995) Gastroenterology , vol.108 , pp. 1097-1103
    • Olafsson, S.1    Gottstein, J.2    Blei, A.T.3
  • 101
    • 60749102384 scopus 로고    scopus 로고
    • Albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure
    • Pares A. Deulofeu R. Cisneros L. Escorsell A. Salmeron J. M. Caballeria J. Mas A. (2009). Albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure. Crit Care 13, R8.
    • (2009) Crit Care , vol.13 , pp. R8
    • Pares, A.1    Deulofeu, R.2    Cisneros, L.3    Escorsell, A.4    Salmeron, J.M.5    Caballeria, J.6    Mas, A.7
  • 103
    • 1642457265 scopus 로고    scopus 로고
    • Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons
    • Pellerin L. Magistretti P. J. (2004). Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10, 53–62.
    • (2004) Neuroscientist , vol.10 , pp. 53-62
    • Pellerin, L.1    Magistretti, P.J.2
  • 106
    • 34249003300 scopus 로고    scopus 로고
    • Inhibition of glutamine transport into mitochondria protects astrocytes from ammonia toxicity
    • Pichili V. B. Rao K. V. Jayakumar A. R. Norenberg M. D. (2007). Inhibition of glutamine transport into mitochondria protects astrocytes from ammonia toxicity. Glia 55, 801–9.
    • (2007) Glia , vol.55 , pp. 801-809
    • Pichili, V.B.1    Rao, K.V.2    Jayakumar, A.R.3    Norenberg, M.D.4
  • 107
    • 0020556199 scopus 로고
    • The brain in experimental portal-systemic encephalopathy. I. Morphological changes in three animal models
    • Pilbeam C. M. Anderson R. M. Bhathal P. S. (1983). The brain in experimental portal-systemic encephalopathy. I. Morphological changes in three animal models. J Pathol 140, 331–45.
    • (1983) J Pathol , vol.140 , pp. 331-345
    • Pilbeam, C.M.1    Anderson, R.M.2    Bhathal, P.S.3
  • 108
    • 60349125886 scopus 로고    scopus 로고
    • Reassessing the amyloid cascade hypothesis of Alzheimer’s disease
    • Pimplikar S. W. (2009). Reassessing the amyloid cascade hypothesis of Alzheimer’s disease. Int J Biochem Cell Biol 41, 1261–68.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1261-1268
    • Pimplikar, S.W.1
  • 109
    • 0002624463 scopus 로고    scopus 로고
    • ROS and Parkinson’s disease: A view to a kill
    • Poli, G., Cadenas, E., Packer, L., eds.), pp., New York, NY, Marcel Dekker
    • Przedborski S. Jackson-Lewis V. (2000). ROS and Parkinson’s disease: A view to a kill. In Free Radicals in Brain Pathophysiology (Poli G. Cadenas E. Packer L. eds.), pp. 273–90. New York, NY: Marcel Dekker.
    • (2000) Free Radicals in Brain Pathophysiology , pp. 273-290
    • Przedborski, S.1    Jackson-Lewis, V.2
  • 110
    • 0024282594 scopus 로고
    • Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture
    • Raff M. C. Lillien L. E. Richardson W. D. Burne J. F. Noble M. D. (1988). Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333, 562–65.
    • (1988) Nature , vol.333 , pp. 562-565
    • Raff, M.C.1    Lillien, L.E.2    Richardson, W.D.3    Burne, J.F.4    Noble, M.D.5
  • 111
    • 0344549778 scopus 로고    scopus 로고
    • Suppression of ammonia-induced astrocyte swelling by cyclosporin A
    • Rama Rao K. V. Chen M. Simard J. M. Norenberg M. D. (2003). Suppression of ammonia-induced astrocyte swelling by cyclosporin A. J Neurosci Res 74, 891–97.
    • (2003) J Neurosci Res , vol.74 , pp. 891-897
    • Rama Rao, K.V.1    Chen, M.2    Simard, J.M.3    Norenberg, M.D.4
  • 112
    • 77749237129 scopus 로고    scopus 로고
    • Brain edema in acute liver failure: Inhibition by L-histidine
    • Rama Rao K. V. Reddy P. V. Tong X. Norenberg M. D. (2010). Brain edema in acute liver failure: Inhibition by L-histidine. Am J Pathol 176, 1400–1408.
    • (2010) Am J Pathol , vol.176 , pp. 1400-1408
    • Rama Rao, K.V.1    Reddy, P.V.2    Tong, X.3    Norenberg, M.D.4
  • 114
    • 0017173212 scopus 로고
    • Plasma and brain amino acids in fulminant hepatic failure and their relationship to hepatic encephalopathy
    • Record C. O. Buxton B. Chase R. A. Curzon G. Murray-Lyon I. M. Williams R. (1976). Plasma and brain amino acids in fulminant hepatic failure and their relationship to hepatic encephalopathy. Eur J Clin Invest 6, 387–94.
    • (1976) Eur J Clin Invest , vol.6 , pp. 387-394
    • Record, C.O.1    Buxton, B.2    Chase, R.A.3    Curzon, G.4    Murray-Lyon, I.M.5    Williams, R.6
  • 120
    • 0002965971 scopus 로고
    • Astrocyte-derived neurotrophic factors
    • Murphy, S., Ed.), pp., San Diego, CA, Academic Press
    • Rudge J. S. (1993). Astrocyte-derived neurotrophic factors. In Astrocytes: Pharmacology and Function (Murphy S. Ed.), pp. 267–305. San Diego, CA: Academic Press.
    • (1993) Astrocytes: Pharmacology and Function , pp. 267-305
    • Rudge, J.S.1
  • 121
    • 0025948113 scopus 로고
    • The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
    • Rushmore T. H. Morton M. R. Pickett C. B. (1991). The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266, 11632–39.
    • (1991) J Biol Chem , vol.266 , pp. 11632-11639
    • Rushmore, T.H.1    Morton, M.R.2    Pickett, C.B.3
  • 122
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara J. I. Miura K. Bannai S. (1993). Maintenance of neuronal glutathione by glial cells. J Neurochem 61, 1672–76.
    • (1993) J Neurochem , vol.61 , pp. 1672-1676
    • Sagara, J.I.1    Miura, K.2    Bannai, S.3
  • 123
    • 0030848038 scopus 로고    scopus 로고
    • Reduction of infarct volume by halothane: Effect on cerebral blood flow or perifocal spreading depression-like depolarizations
    • Saito R. Graf R. Hubel K. Fujita T. Rosner G. Heiss W. D. (1997). Reduction of infarct volume by halothane: Effect on cerebral blood flow or perifocal spreading depression-like depolarizations. J Cereb Blood Flow Metab 17, 857–64.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 857-864
    • Saito, R.1    Graf, R.2    Hubel, K.3    Fujita, T.4    Rosner, G.5    Heiss, W.D.6
  • 124
    • 0019347565 scopus 로고
    • Transport and metabolism of glutamate and GABA in neurons and glial cells
    • Schousboe A. (1981). Transport and metabolism of glutamate and GABA in neurons and glial cells. Int Rev Neurobiol 22, 1–45.
    • (1981) Int Rev Neurobiol , vol.22 , pp. 1-45
    • Schousboe, A.1
  • 125
    • 0028841691 scopus 로고
    • Surface complexity of human neocortical astrocytic cells: Changes with development, aging, and dementia
    • Senitz D. Reichenbach A. Smith T. G. (1995). Surface complexity of human neocortical astrocytic cells: Changes with development, aging, and dementia. J Hirnforsch 36, 531–37.
    • (1995) J Hirnforsch , vol.36 , pp. 531-537
    • Senitz, D.1    Reichenbach, A.2    Smith, T.G.3
  • 126
    • 9144274476 scopus 로고    scopus 로고
    • Ex vivo analysis of lactate and glucose metabolism in the rat brain under different states of depressed activity
    • Serres S. Bezancon E. Franconi J. M. Merle M. (2004). Ex vivo analysis of lactate and glucose metabolism in the rat brain under different states of depressed activity. J Biol Chem 279, 47881–89.
    • (2004) J Biol Chem , vol.279 , pp. 47881-47889
    • Serres, S.1    Bezancon, E.2    Franconi, J.M.3    Merle, M.4
  • 127
    • 12244301600 scopus 로고    scopus 로고
    • Ex vivo NMR study of lactate metabolism in rat brain under various depressed states
    • Serres S. Bezancon E. Franconi J. M. Merle M. (2005). Ex vivo NMR study of lactate metabolism in rat brain under various depressed states. J Neurosci Res 79, 19–25.
    • (2005) J Neurosci Res , vol.79 , pp. 19-25
    • Serres, S.1    Bezancon, E.2    Franconi, J.M.3    Merle, M.4
  • 129
    • 0021988603 scopus 로고
    • Pyruvate carboxylase: An astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools
    • Shank R. P. Bennett G. S. Freytag S. O. Campbell G. L. (1985). Pyruvate carboxylase: An astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools. Brain Res 329, 364–67.
    • (1985) Brain Res , vol.329 , pp. 364-367
    • Shank, R.P.1    Bennett, G.S.2    Freytag, S.O.3    Campbell, G.L.4
  • 130
    • 0035369252 scopus 로고    scopus 로고
    • The uptake of cysteine in cultured primary astrocytes and neurons
    • Shanker G. Allen J. W. Mutkus L. A. Aschner M. (2001). The uptake of cysteine in cultured primary astrocytes and neurons. Brain Res 902, 156–63.
    • (2001) Brain Res , vol.902 , pp. 156-163
    • Shanker, G.1    Allen, J.W.2    Mutkus, L.A.3    Aschner, M.4
  • 132
    • 27144492341 scopus 로고    scopus 로고
    • The pathophysiologic basis of hepatic encephalopathy: Central role for ammonia and inflammation
    • Shawcross D. Jalan R. (2005). The pathophysiologic basis of hepatic encephalopathy: Central role for ammonia and inflammation. Cell Mol Life Sci 62, 2295–2304.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2295-2304
    • Shawcross, D.1    Jalan, R.2
  • 134
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain
    • Storck T. Schulte S. Hofmann K. Stoffel W. (1992). Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci U S A 89, 10955–59.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10955-10959
    • Storck, T.1    Schulte, S.2    Hofmann, K.3    Stoffel, W.4
  • 135
    • 0026004760 scopus 로고
    • Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats
    • Takahashi H. Koehler R. C. Brusilow S. W. Traystman R. J. (1991). Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats. Am J Physiol 261, H825–29.
    • (1991) Am J Physiol , vol.261 , pp. H825-H829
    • Takahashi, H.1    Koehler, R.C.2    Brusilow, S.W.3    Traystman, R.J.4
  • 136
    • 60849101949 scopus 로고    scopus 로고
    • Connexin and pannexin hemichannels of neurons and astrocytes
    • Thompson R. J. MacVicar B.A. (2008). Connexin and pannexin hemichannels of neurons and astrocytes. Channels 2, 81–86.
    • (2008) Channels , vol.2 , pp. 81-86
    • Thompson, R.J.1    MacVicar, B.A.2
  • 137
    • 77950949737 scopus 로고    scopus 로고
    • Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: A potential role in Alzheimer’s disease
    • Tian G. Kong Q. Lai L. Ray-Chaudhury A. Lin C. L. (2010). Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: A potential role in Alzheimer’s disease. J Neurochem 113, 978–89.
    • (2010) J Neurochem , vol.113 , pp. 978-989
    • Tian, G.1    Kong, Q.2    Lai, L.3    Ray-Chaudhury, A.4    Lin, C.L.5
  • 138
    • 0023607036 scopus 로고
    • Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: Ultrastructure and integrity of the blood-brain barrier
    • Traber P. G. Dal Canto M. Ganger D. R. Blei A. T. (1987). Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: Ultrastructure and integrity of the blood-brain barrier. Hepatology 7, 1272–77.
    • (1987) Hepatology , vol.7 , pp. 1272-1277
    • Traber, P.G.1    Dal Canto, M.2    Ganger, D.R.3    Blei, A.T.4
  • 139
    • 0015071185 scopus 로고
    • A stimulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain
    • van den Berg C. J. Garfinkel D. (1971). A stimulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain. Biochem J 123, 211–18.
    • (1971) Biochem J , vol.123 , pp. 211-218
    • van den Berg, C.J.1    Garfinkel, D.2
  • 140
    • 0031106002 scopus 로고    scopus 로고
    • Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: A role for transforming growth factor beta
    • Vincent V. A. Tilders F. J. Van Dam A. M. (1997). Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: A role for transforming growth factor beta. Glia 19, 190–98.
    • (1997) Glia , vol.19 , pp. 190-198
    • Vincent, V.A.1    Tilders, F.J.2    Van Dam, A.M.3
  • 141
    • 0024458542 scopus 로고
    • Role of glial cells in the regulation of the brain ion microenvironment
    • Walz W. (1989). Role of glial cells in the regulation of the brain ion microenvironment. Prog Neurobiol 33, 309–33.
    • (1989) Prog Neurobiol , vol.33 , pp. 309-333
    • Walz, W.1
  • 142
    • 0001412747 scopus 로고    scopus 로고
    • Astrocytes provide cysteine to neurons by releasing glutathione
    • Wang X. F. Cynader M. S. (2000). Astrocytes provide cysteine to neurons by releasing glutathione. J Neurochem 74, 1434–42.
    • (2000) J Neurochem , vol.74 , pp. 1434-1442
    • Wang, X.F.1    Cynader, M.S.2
  • 143
    • 0001697979 scopus 로고
    • Effect of an inhibitor of glutamine synthesis (methionine sulfoximine) on ammonia toxicity and metabolism
    • Warren K. S. Schenker S. (1964). Effect of an inhibitor of glutamine synthesis (methionine sulfoximine) on ammonia toxicity and metabolism. J Lab Clin Med 64, 442–49.
    • (1964) J Lab Clin Med , vol.64 , pp. 442-449
    • Warren, K.S.1    Schenker, S.2
  • 144
    • 0034295217 scopus 로고    scopus 로고
    • Microglia cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plague degradation
    • Wegiel J. Wang K. C. Tarnawski M. Lach B. (2000). Microglia cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plague degradation. Acta Neuropathol 100, 356–64.
    • (2000) Acta Neuropathol , vol.100 , pp. 356-364
    • Wegiel, J.1    Wang, K.C.2    Tarnawski, M.3    Lach, B.4
  • 145
    • 0030174754 scopus 로고    scopus 로고
    • Evaluation of the importance of transamination versus deamination in astrocytic metabolism of [U-13C]glutamate
    • Westergaard N. Drejer J. Schousboe A. Sonnewald U. (1996). Evaluation of the importance of transamination versus deamination in astrocytic metabolism of [U-13C]glutamate. Glia 17, 160–68.
    • (1996) Glia , vol.17 , pp. 160-168
    • Westergaard, N.1    Drejer, J.2    Schousboe, A.3    Sonnewald, U.4
  • 148
    • 77954392450 scopus 로고    scopus 로고
    • Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia
    • Xu L. Emery J. F. Ouyang Y. B. Voloboueva L. A. Giffard R. G. (2010). Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia. Glia 58, 1042–49.
    • (2010) Glia , vol.58 , pp. 1042-1049
    • Xu, L.1    Emery, J.F.2    Ouyang, Y.B.3    Voloboueva, L.A.4    Giffard, R.G.5
  • 149
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
    • Yankner B. A. Duffy L. K. Kirschner D. A. (1990). Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides. Science 250, 279–82.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 150
    • 0021037707 scopus 로고
    • Pyruvate carboxylase activity in primary cultures of astrocytes and neurons
    • Yu A. C. Drejer J. Hertz L. Schousboe A. (1983). Pyruvate carboxylase activity in primary cultures of astrocytes and neurons. J Neurochem 41, 1484–87.
    • (1983) J Neurochem , vol.41 , pp. 1484-1487
    • Yu, A.C.1    Drejer, J.2    Hertz, L.3    Schousboe, A.4
  • 151
    • 20044379940 scopus 로고    scopus 로고
    • 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity
    • Zhang W. Qin L. Wang T. Wei S. J. Gao H. M. Liu J. Wilson B. Liu B. Kim H. C. Hong J. S. (2005). 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity. FASEB J 19, 395–97.
    • (2005) FASEB J , vol.19 , pp. 395-397
    • Zhang, W.1    Qin, L.2    Wang, T.3    Wei, S.J.4    Gao, H.M.5    Liu, J.6    Wilson, B.7    Liu, B.8    Kim, H.C.9    Hong, J.S.10
  • 152
    • 1442263100 scopus 로고    scopus 로고
    • Effects of methionine sulfoximine on the glutamine and glutamate content and cell volume in rat cerebral cortical slices: Involvement of mechanisms not related to inhibition of glutamine synthesis
    • Zielinska M. Stafiej A. Law R. O. Albrecht J. (2004). Effects of methionine sulfoximine on the glutamine and glutamate content and cell volume in rat cerebral cortical slices: Involvement of mechanisms not related to inhibition of glutamine synthesis. Neurotoxicology 25, 443–49.
    • (2004) Neurotoxicology , vol.25 , pp. 443-449
    • Zielinska, M.1    Stafiej, A.2    Law, R.O.3    Albrecht, J.4
  • 153
    • 0037311146 scopus 로고    scopus 로고
    • Selective increase of brain lactate synthesis in experimental acute liver failure: Results of a [H-C] nuclear magnetic resonance study
    • Zwingmann C. Chatauret N. Leibfritz D. Butterworth R. F. (2003). Selective increase of brain lactate synthesis in experimental acute liver failure: Results of a [H-C] nuclear magnetic resonance study. Hepatology 37, 420–28.
    • (2003) Hepatology , vol.37 , pp. 420-428
    • Zwingmann, C.1    Chatauret, N.2    Leibfritz, D.3    Butterworth, R.F.4
  • 154
    • 1642513500 scopus 로고    scopus 로고
    • Selective alterations of brain osmolytes in acute liver failure: Protective effect of mild hypothermia
    • Zwingmann C. Chatauret N. Rose C. Leibfritz D. Butterworth R. F. (2004). Selective alterations of brain osmolytes in acute liver failure: Protective effect of mild hypothermia. Brain Res 999, 118–23.
    • (2004) Brain Res , vol.999 , pp. 118-123
    • Zwingmann, C.1    Chatauret, N.2    Rose, C.3    Leibfritz, D.4    Butterworth, R.F.5


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