Gamma-secretase inhibitor activity of a pterocarpus erinaceus extract

Neurodegenerative Diseases

Volumn 14, Issue 1, 2014, Pages 39-51

  Hage, Salim ^a   Marinangeli, Claudia ^b   Stanga, Serena ^b   Octave, Jean Noël ^b   Quetin Leclercq, Joëlle ^a   Kienlen Campard, Pascal ^b  

^a UCLouvain   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Pharmacognosy; Pterocarpus erinaceus; Amyloid peptide; Secretase inhibitor

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE INHIBITOR; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROPROTECTIVE AGENT; NOTCH RECEPTOR; PLANT EXTRACT; PRESENILIN 1; PRESENILIN 2; PTEROCARPUS ERINACEUS EXTRACT; UNCLASSIFIED DRUG; ENZYME INHIBITOR; SECRETASE; AMYLOID BETA PROTEIN 38;

ANIMAL CELL; ARTICLE; BARK; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NERVE CELL DIFFERENTIATION; NONHUMAN; PLANT STEM; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; PTEROCARPUS; PTEROCARPUS ERINACEUS; TRANSACTIVATION ASSAY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CRICETULUS; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; HAMSTER; HUMAN; METABOLISM; MOUSE; WESTERN BLOTTING; ALZHEIMER DISEASE; CARBOXY TERMINAL SEQUENCE; DRUG ACTIVITY; DRUG TARGETING; FEMALE; NERVE CELL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICE; PLANT EXTRACTS; PTEROCARPUS; TRANSFECTION;

EID: 84903734486     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000355557     Document Type: Article

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