Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Galan, Alba ^a   Dergham, Pauline ^a   Escoll, Pedro ^b   De la Hera, Antonio ^b   D'Onofrio, Philippe M ^c   Magharious, Mark M ^c   Koeberle, Paulo D ^d   Frade, José María ^e   Saragovi, H Uri ^a,f,g  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF ALCALÁ   (Spain)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e INSTITUTO CAJAL   (Spain)

^f MCGILL UNIVERSITY   (Canada)

^g MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN S6; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPONENT; CELL COUNT; CELL CYCLE; CELL CYCLE REENTRY; CELL DEATH; CELL INTERACTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA HYPERPLOIDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GLIA; INTRACELLULAR SIGNALING; KINETICS; MITOSIS; NERVE CELL; NERVE CELL DEGENERATION; NERVE FIBER; NERVE FIBER TRANSECTION; NONHUMAN; OPTIC NERVE; PATHOGENESIS; PLOIDY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; RETINA GANGLION CELL; RETINA GYRATE ATROPHY; RETINAL GANGLION CELL DEGENERATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; COMPLICATION; ENZYMOLOGY; METABOLISM; OPTIC NERVE INJURY; PATHOPHYSIOLOGY; RETINA; RETINAL DEGENERATION; WISTAR RAT;

ANIMALS; AXOTOMY; CELL CYCLE; CELL DEATH; FEMALE; KINETICS; NEUROGLIA; OPTIC NERVE; OPTIC NERVE INJURIES; RATS; RATS, WISTAR; RETINA; RETINAL DEGENERATION; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION;

EID: 84903725934     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101349     Document Type: Article

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