A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

EMBO Molecular Medicine

Volumn 6, Issue 7, 2014, Pages 882-901

  Duquet, Arnaud ^a   Melotti, Alice ^a   Mishra, Sonakshi ^a   Malerba, Monica ^a   Seth, Chandan ^a   Conod, Arwen ^a   Ruiz i Altaba, Ariel ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Cancer; in vivo assay; Metastatic suppressor; WNT TCF

Indexed keywords

T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX12; TUMOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; BETA CATENIN; SOX12 PROTEIN, HUMAN; TMED3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX; VESICULAR TRANSPORT PROTEIN;

ADVANCED CANCER; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL SPREADING; COLON CANCER; CONTROLLED STUDY; GENE; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN SECRETION; SPHEROID CELL; TMED3 GENE; TRANSCRIPTION REGULATION; TUMOR GENE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; XENOGRAFT; ANIMAL; CELL MOTION; COLON; COLON TUMOR; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; GENOME; METABOLISM; METASTASIS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WNT SIGNALING PATHWAY;

ANIMALS; BETA CATENIN; CELL LINE, TUMOR; CELL MOVEMENT; COLON; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENOME; HUMANS; MICE; NEOPLASM METASTASIS; SIGNAL TRANSDUCTION; SOXC TRANSCRIPTION FACTORS; TCF TRANSCRIPTION FACTORS; VESICULAR TRANSPORT PROTEINS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84903704101     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201303799     Document Type: Article

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