Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

Molecular and Cellular Biology

Volumn 28, Issue 15, 2008, Pages 4675-4687

  Hoser, Melanie ^a   Potzner, Michaela R ^a   Koch, Julia M C ^a   Bösl, Michael R ^b   Wegner, Michael ^a   Sock, Elisabeth ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SOX 12 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX11; TRANSCRIPTION FACTOR SOX4;

ANIMAL CELL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA BINDING; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FERTILITY; GENE; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; REDUNDANCY ANALYSIS; SOX11 GENE; SOX12 GENE; SOX4 GENE;

ANIMALS; CELL LINE; CHICKENS; DNA; DNA-BINDING PROTEINS; EMBRYONIC DEVELOPMENT; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; HIGH MOBILITY GROUP PROTEINS; HUMANS; MICE; MICE, INBRED C57BL; MUTAGENESIS; PHENOTYPE; PROTEIN BINDING; SPINAL CORD; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

MUS;

EID: 47949105017     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00338-08     Document Type: Article

References (36)

1. Bergsland, M., M. Werme, M. Malewicz, T. Perlmann, and J. Muhr. 2006. The establishment of neuronal properties is controlled by Sox4 and Sox11. Genes Dev. 20:3475-3486.
2. Bi, W., J. M. Deng, Z. Zhang, R. R. Behringer, and B. de Crombrugghe. 1999. Sox9 is required for cartilage formation. Nat. Genet. 22:85-89.
3. Bowles, J., G. Schepers, and P. Koopman. 2000. Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev. Biol. 227:239-255.
4. Britsch, S., D. E. Goerich, D. Riethmacher, R. I. Peirano, M. Rossner, K. A. Nave, C. Birchmeier, and M. Wegner. 2001. The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 15:66-78.
5. Cheung, M., M. Abu-Elmagd, H. Clevers, and P. J. Scotting. 2000. Roles of Sox4 in central nervous system development. Mol. Brain Res. 79:180-191.
6. Hamburger, H., and H. L. Hamilton. 1953. A series of normal stages in the development of the chick embryo. J. Morphol. 88:49-92.
7. Hargrave, M., E. Wright, J. Kun, J. Emery, L. Cooper, and P. Koopman. 1997. Expression of the Sox11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Dev. Dyn. 210: 79-86.
8. Hoser, M., S. L. Baader, M. R. Bosl, A. Ihmer, M. Wegner, and E. Sock. 2007. Prolonged glial expression of Sox4 in the CNS leads to architectural cerebellar defects and ataxia. J. Neurosci. 27:5495-5505.
9. Jay, P., I. Sahly, C. Goze, S. Taviaux, F. Poulat, G. Couly, M. Abitbol, and P. Berta. 1997. Sox22 is a new member of the Sox gene family, mainly expressed in human nervous tissue. Hum. Mol. Gen. 6:1069-1077.
10. Kellerer, S., S. Schreiner, C. C. Stolt, M. R. Bösl, and M. Wegner. 2006. Functional equivalency of transcription factors Sox8 and Sox10 is tissue-specific. Development 133:2875-2886.
11. Kuhlbrodt, K., B. Herbarth, E. Sock, J. Enderich, I. Hermans-Borgmeyer, and M. Wegner. 1998. Cooperative function of POU proteins and Sox proteins in glial cells. J. Biol. Chem. 273:16050-16057.
12. Kuhlbrodt, K., B. Herbarth, E. Sock, I. Hermans-Borgmeyer, and M. Wegner. 1998. Sox10, a novel transcriptional modulator in glial cells. J. Neurosci. 18:237-250.
13. Lakso, M., J. G. Pichel, J. R. Gorman, B. Sauer, Y. Okamoto, E. Lee, F. W. Alt, and H. Westphal. 1996. Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl. Acad. Sci. USA 93:5860-5865.
14. Maka, M., C. C. Stolt, and M. Wegner. 2005. Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev. Biol. 277:155-169.
15. Mavropoulos, A., N. Devos, F. Biemar, E. Zecchin, F. Argenton, H. Edlund, P. Motte, J. Martial, and B. Peers. 2005. sox4b is a key player of pancreatic alpha cell differentiation in zebrafish. Dev. Biol. 285:211-223.
16. Nissen-Meyer, L. S., R. Jemtland, V. T. Gautvik, M. E. Pedersen, R. Paro, D. Fortunati, D. D. Pierroz, V. A. Stadelmann, S. Reppe, F. P. Reinholt, A. Del Fattore, N. Rucci, A. Teti, S. Ferrari, and K. M. Gautvik. 2007. Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice. J. Cell Sci. 120:2785-2795.
17. Potzner, M., C. Griffel, E. Lütjen-Drecoll, M. R. Bösl, M. Wegner, and E. Sock. 2007. Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system. Mol. Cell. Biol. 27:5316-5326.
18. Renner, K., H. Leger, and M. Wegner. 1994. The POU-domain protein Tst-1 and papovaviral T-antigen function synergistically to stimulate glia-specific gene expression of JC virus. Proc. Natl. Acad. Sci. USA 91:6433-6437.
19. Rideout, W. M., T. Wakayama, T. Wutz, K. Eggan, L. Jackson-Grusby, J. Dausman, R. Yanagimachi, and R. Jaenisch. 2000. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nat. Genet. 24:109-110.
20. Rimini, R., M. Beltrame, F. Argenton, D. Szymczak, F. Cotelli, and M. E. Bianchi. 1999. Expression patterns of zebrafish sox11A, sox11B and sox21. Mech. Dev. 89:167-171.
21. Sandberg, M., M. Källstrom, and J. Muhr. 2005. Sox21 promotes the progression of vertebrate neurogenesis. Nat. Neurosci. 8:995-1001.
22. Schepers, G. E., R. D. Taesdale, and P. Koopman. 2002. Twenty pairs of Sox: extent, homology, and nomenclature of the mouse and human Sox transcription factor families. Dev. Cell 3:167-170.
23. Schilham, M. W., M. A. Oosterwegel, P. Moerer, J. Ya, P. A. J. Deboer, M. Vandewetering, S. Verbeek, W. H. Lamers, A. M. Kruisbeek, A. Cumano, and H. Clevers. 1996. Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4. Nature 380:711-714.
24. Schreiber, J., J. Enderich, E. Sock, C. Schmidt, C. Richter-Landsberg, and M. Wegner. 1997. Redundancy of class III POU proteins in the oligodendrocyte lineage. J. Biol. Chem. 272:32286-32293.
25. Sock, E., S. D. Rettig, J. Enderich, M. R. Bösl, E. R. Tamm, and M. Wegner. 2004. Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol. Cell. Biol. 24:6635-6644.
26. Sock, E., K. Schmidt, I. Hermanns-Borgmeyer, M. R. Bösl, and M. Wegner. 2001. Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8. Mol. Cell. Biol. 21:6951-6959.
27. Tanaka, S., Y. Kamachi, A. Tanouchi, H. Hamada, N. Jing, and H. Kondoh. 2004. Interplay of SOX and POU factors in regulation of the nestin gene in neural primordial cells. Mol. Cell. Biol. 24:8834-8846.
28. Uchikawa, M., Y. Kamachi, and H. Kondoh. 1999. Two distinct subgroups of group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken. Mech. Dev. 84:103-120.
29. Uwanogho, D., M. Rex, E. J. Cartwright, G. Pearl, C. Healy, P. J. Scotting, and P. T. Sharpe. 1995. Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development. Mech. Dev. 49:23-36.
30. van de Wetering, M., M. Oosterwegel, K. van Norren, and H. Clevers. 1993. Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J. 12:3847-3854.
31. Wegner, M. 1999. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res. 27:1409-1420.
32. Wegner, M., and C. C. Stolt. 2005. From stem cells to neurons and glia: a soxist's view of neural development. Trends Neurosci. 28:583-588.
33. Wiebe, M. S., T. K. Nowling, and A. Rizzino. 2003. Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity. J. Biol. Chem. 278:17901-17911.
34. Wilson, M. E., K. Y. Yang, A. Kalousova, J. Lau, Y. Kosaka, F. C. Lynn, J. Wang, C. Mrejen, V. Episkopou, H. C. Clevers, and M. S. German. 2005. The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas. Diabetes 54:3402-3409.
35. Wurm, A., E. Sock, R. Fuchshofer, M. Wegner, and E. R. Tamm. 2008. Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11. Exp. Eye Res. 86:895-907.
36. Yuan, H. B., N. Corbi, C. Basilico, and L. Dailey. 1995. Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev. 9:2635-2645.