The gold domain-containing protein TMED1 is involved in interleukin-33 signaling

Journal of Biological Chemistry

Volumn 288, Issue 8, 2013, Pages 5616-5623

  Connolly, J ^a   O'Neil, Luke A J ^a   McGettrick, Anne F ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

DOMAIN-CONTAINING PROTEINS; SIGNAL ACTIVATION; SIGNALING PATHWAYS;

BIOCHEMISTRY; BIOLOGY;

PROTEINS;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 33; INTERLEUKIN 6; INTERLEUKIN 8; MEMBRANE PROTEIN; SMALL INTERFERING RNA; ST2 LIGAND; TRANSMEMBRANE EMP24 DOMAIN CONTAINING PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENE MUTATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; INNATE IMMUNITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

GENE EXPRESSION REGULATION; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNE SYSTEM; IMMUNOPRECIPITATION; INTERLEUKIN-6; INTERLEUKIN-8; INTERLEUKINS; MICROSCOPY, CONFOCAL; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VESICULAR TRANSPORT PROTEINS;

EID: 84874320548     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.403899     Document Type: Article

References (28)

1. Tago, K., Noda, T., Hayakawa, M., Iwahana, H., Yanagisawa, K., Yashiro, T., and Tominaga, S. (2001) Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V. Biochem. Biophys. Res. Commun. 285, 1377-1383
2. Li, H., Tago, K., Io, K., Kuroiwa, K., Arai, T., Iwahana, H., Tominaga, S., and Yanagisawa, K. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics 67, 284-290
3. Schmitz, J., Owyang, A., Oldham, E., Song, Y., Murphy, E., McClanahan, T. K., Zurawski, G., Moshrefi, M., Qin, J., Li, X., Gorman, D. M., Bazan, J. F., and Kastelein, R. A. (2005) IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and inducesThelper type 2-associated cytokines. Immunity 23, 479-490
4. Mirchandani, A. S., Salmond, R. J., and Liew, F. Y. (2012) Interleukin-33 and the function of innate lymphoid cells. Trends Immunol. 33, 389-396
5. Palmer, G., Lipsky, B. P., Smithgall, M. D., Meininger, D., Siu, S., Talabot-Ayer, D., Gabay, C., and Smith, D. E. (2008) The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling, and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33. Cytokine 42, 358-364
6. Chackerian, A. A., Oldham, E. R., Murphy, E. E., Schmitz, J., Pflanz, S., and Kastelein, R. A. (2007) IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex. J. Immunol. 179, 2551-2555
7. Funakoshi-Tago, M., Tago, K., Hayakawa, M., Tominaga, S., Ohshio, T., Sonoda, Y., and Kasahara, T. (2008) TRAF6 is a critical signal transducer in IL-33 signaling pathway. Cell. Signal. 20, 1679-1686
8. Hayakawa, H., Hayakawa, M., Kume, A., and Tominaga, S. (2007) Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation. J. Biol. Chem. 282, 26369-26380
9. Lüthi, A. U., Cullen, S. P., McNeela, E. A., Duriez, P. J., Afonina, I. S., Sheridan, C., Brumatti, G., Taylor, R. C., Kersse, K., Vandenabeele, P., Lavelle, E. C., and Martin, S. J. (2009) Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 31, 84-98
10. Talabot-Ayer, D., Lamacchia, C., Gabay, C., and Palmer, G. (2009) Interleukin-33 is biologically active independently of caspase-1 cleavage. J. Biol. Chem. 284, 19420-19426
11. Liew, F. Y., Pitman, N. I., and McInnes, I. B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat. Rev. Immunol 10, 103-110
12. Oboki, K., Ohno, T., Kajiwara, N., Saito, H., and Nakae, S. (2010) IL-33 and IL-33 receptors in host defense and diseases. Allergol. Int. 59, 143-160
13. Bulek, K., Swaidani, S., Qin, J., Lu, Y., Gulen, M. F., Herjan, T., Min, B., Kastelein, R. A., Aronica, M., Kosz-Vnenchak, M., and Li, X. (2009) The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response. J. Immunol. 182, 2601-2609
14. Zhao, J., Wei, J., Mialki, R. K., Mallampalli, D. F., Chen, B. B., Coon, T., Zou, C., Mallampalli, R. K., and Zhao, Y. (2012) F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation. Nat. Immunol. 13, 651-658
15. Strating, J. R., and Martens, G. J. (2009) The p24 family and selective transport processes at the ER-Golgi interface. Biol. Cell 101, 495-509
16. Jenne, N., Frey, K., Brugger, B., and Wieland, F. T. (2002) Oligomeric state and stoichiometry of p24 proteins in the early secretory pathway. J. Biol. Chem. 277, 46504-46511
17. Carney, G. E., and Bowen, N. J. (2004) p24 proteins, intracellular trafficking, and behavior: Drosophila melanogaster provides insights and opportunities. Biol. Cell 96, 271-278
18. Anantharaman, V., and Aravind, L. (2002) The GOLD domain, a novel protein module involved in Golgi function and secretion. Genome Biol. 3, research0023
19. Boltz, K. A., and Carney, G. E. (2008) Loss of p24 function in Drosophila melanogaster causes a stress response and increased levels of NF-B-regulated gene products. BMC Genomics 9, 212
20. Doyle, S. L., Husebye, H., Connolly, D. J., Espevik, T., O'Neill, L. A., and McGettrick, A. F. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nat. Commun. 3, 707
21. Palsson-McDermott, E. M., Doyle, S. L., McGettrick, A. F., Hardy, M., Husebye, H., Banahan, K., Gong, M., Golenbock, D., Espevik, T., and O'Neill, L. A. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nat. Immunol. 10, 579-586
22. Gayle, M. A., Slack, J. L., Bonnert, T. P., Renshaw, B. R., Sonoda, G., Taguchi, T., Testa, J. R., Dower, S. K., and Sims, J. E. (1996) Cloning of a putative ligand for the T1/ST2 receptor. J. Biol. Chem. 271, 5784-5789
23. Brint, E. K., Xu, D., Liu, H., Dunne, A., McKenzie, A. N., O'Neill, L. A., and Liew, F. Y. (2004) ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat. Immunol. 5, 373-379
24. O'Neill, L. A. (2008) The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol. Rev. 226, 10-18
25. Lorenz, H., Hailey, D. W., and Lippincott-Schwartz, J. (2006) Fluorescence protease protection of GFP chimeras to reveal protein topology and subcellular localization. Nat. Methods 3, 205-210
26. Jun, Y., and Ahn, K. (2011) Tmp21, a novel MHC-I interacting protein, preferentially binds to-2-microglobulin-free MHC-I heavy chains. BMB Rep. 44, 369-374
27. McGettrick, A. F., and O'Neill, L. A. (2010) Localisation and trafficking of Toll-like receptors: an important mode of regulation. Curr. Opin. Immunol. 22, 20-27
28. Emery, G., Rojo, M., and Gruenberg, J. (2000) Coupled transport of p24 family members. J. Cell Sci. 113, 2507-2516