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Volumn 28, Issue 7, 2014, Pages 2775-2789

RORo: And ROR 7 are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D

Author keywords

CYP11A1; Keratinocytes; Melanoma cells; Retinoic acid related nuclear receptors

Indexed keywords

20 HYDROXYVITAMIN D; 20,23 DIHYDROXYVITAMIN D; 5 METHOXYTRYPTAMINE; 5 METHOXYTRYPTOPHOL; 6 HYDROXYMELATONIN; CALCITRIOL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLOPHILIN B; GLUCOSE 6 PHOSPHATASE; INTERLEUKIN 17; LAMIN A; PROTEIN BMAL1; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; UNCLASSIFIED DRUG; VITAMIN D; 20 HYDROXYVITAMIN D3; 20,23 DIHYDROXYVITAMIN D3; 20,23-DIHYDROXYVITAMIN D3; 20-HYDROXYVITAMIN D3; ARNTL PROTEIN, HUMAN; CALCIFEDIOL; DIHYDROXYCOLECALCIFEROL; DRUG DERIVATIVE; RORA PROTEIN, HUMAN; RORC PROTEIN, HUMAN; TRANSCRIPTION FACTOR ARNTL;

EID: 84903696734     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-242040     Document Type: Article
Times cited : (245)

References (70)
  • 1
    • 66849099394 scopus 로고    scopus 로고
    • Retinoid-related orphan receptors (RORs): Critical roles in development, immunity, circadian rhythm, and cellular metabolism
    • Jetten, A. M. (2009) Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism. Nucl. Recept. Signal. 7, e003
    • (2009) Nucl. Recept. Signal. , vol.7
    • Jetten, A.M.1
  • 3
    • 84866888532 scopus 로고    scopus 로고
    • RORgamma directly regulates the circadian expression of clock genes and downstream targets in vivo
    • Takeda, Y., Jothi, R., Birault, V., and Jetten, A. M. (2012) RORgamma directly regulates the circadian expression of clock genes and downstream targets in vivo. Nucleic Acids Res. 40, 8519-8535
    • (2012) Nucleic Acids Res. , vol.40 , pp. 8519-8535
    • Takeda, Y.1    Jothi, R.2    Birault, V.3    Jetten, A.M.4
  • 4
    • 1842848068 scopus 로고    scopus 로고
    • X-ray structure of the hRORα LBD at 1.63 A: Structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORα
    • DOI 10.1016/S0969-2126(02)00912-7, PII S0969212602009127
    • Kallen, J. A., Schlaeppi, J. M., Bitsch, F., Geisse, S., Geiser, M., Delhon, I., and Fournier, B. (2002) X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha. Structure 10, 1697-1707 (Pubitemid 35452576)
    • (2002) Structure , vol.10 , Issue.12 , pp. 1697-1707
    • Kallen, J.A.1    Schlaeppi, J.-M.2    Bitsch, F.3    Geisse, S.4    Geiser, M.5    Delhon, I.6    Fournier, B.7
  • 5
    • 84869489534 scopus 로고    scopus 로고
    • Action of RORs and their ligands in (patho)physiology
    • Solt, L. A., and Burris, T. P. (2012) Action of RORs and their ligands in (patho)physiology. Trends Endocrinol. Metab. 23, 619-627
    • (2012) Trends Endocrinol. Metab. , vol.23 , pp. 619-627
    • Solt, L.A.1    Burris, T.P.2
  • 6
    • 84865772592 scopus 로고    scopus 로고
    • Small molecule inhibitors of RORgammat: Targeting Th17 cells and other applications
    • Huh, J. R., and Littman, D. R. (2012) Small molecule inhibitors of RORgammat: targeting Th17 cells and other applications. Eur. J. Immunol. 42, 2232-2237
    • (2012) Eur. J. Immunol. , vol.42 , pp. 2232-2237
    • Huh, J.R.1    Littman, D.R.2
  • 7
    • 84893715966 scopus 로고    scopus 로고
    • The therapeutic potential of nuclear receptor modulators for treatment of metabolic disorders: PPARgamma, RORs, and Rev-erbs
    • Marciano, D. P., Chang, M. R., Corzo, C. A., Goswami, D., Lam, V. Q., Pascal, B. D., and Griffin, P. R. (2014) The therapeutic potential of nuclear receptor modulators for treatment of metabolic disorders: PPARgamma, RORs, and Rev-erbs. Cell Metab. 19, 193-208
    • (2014) Cell Metab. , vol.19 , pp. 193-208
    • Marciano, D.P.1    Chang, M.R.2    Corzo, C.A.3    Goswami, D.4    Lam, V.Q.5    Pascal, B.D.6    Griffin, P.R.7
  • 8
    • 84874222674 scopus 로고    scopus 로고
    • Retinoic acid-related orphan receptors alpha and gamma: Key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity
    • Jetten, A. M., Kang, H. S., and Takeda, Y. (2013) Retinoic acid-related orphan receptors alpha and gamma: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity. Front. Endocrinol. (Lausanne) 4, 1
    • (2013) Front. Endocrinol. (Lausanne) , vol.4 , pp. 1
    • Jetten, A.M.1    Kang, H.S.2    Takeda, Y.3
  • 9
    • 1842639533 scopus 로고    scopus 로고
    • Crystal structure of the human rorα Ligand binding domain in complex with cholesterol sulfate at 2.2 A
    • DOI 10.1074/jbc.M400302200
    • Kallen, J., Schlaeppi, J. M., Bitsch, F., Delhon, I., and Fournier, B. (2004) Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2 A. J. Biol. Chem. 279, 14033-14038 (Pubitemid 38468938)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 14033-14038
    • Kallen, J.1    Schlaeppi, J.-M.2    Bitsch, F.3    Delhon, I.4    Fournier, B.5
  • 10
    • 77953243855 scopus 로고    scopus 로고
    • A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hy-droxycholesterol (cerebrosterol)
    • Wang, Y., Kumar, N., Crumbley, C., Griffin, P. R., and Burris, T. P. (2010) A second class of nuclear receptors for oxysterols: regulation of RORalpha and RORgamma activity by 24S-hy-droxycholesterol (cerebrosterol). Biochim. Biophys. Acta 1801, 917-923
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 917-923
    • Wang, Y.1    Kumar, N.2    Crumbley, C.3    Griffin, P.R.4    Burris, T.P.5
  • 12
    • 77954844606 scopus 로고    scopus 로고
    • Structural basis for hydroxycholesterols as natural li-gands of orphan nuclear receptor RORgamma
    • Jin, L., Martynowski, D., Zheng, S., Wada, T., Xie, W., and Li, Y. (2010) Structural basis for hydroxycholesterols as natural li-gands of orphan nuclear receptor RORgamma. Mol. Endocrinol. 24, 923-929
    • (2010) Mol. Endocrinol. , vol.24 , pp. 923-929
    • Jin, L.1    Martynowski, D.2    Zheng, S.3    Wada, T.4    Xie, W.5    Li, Y.6
  • 14
    • 84896713353 scopus 로고    scopus 로고
    • Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis
    • Elias, P. M., Williams, M. L., Choi, E. H., and Feingold, K. R. (2014) Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis. Biochim. Biophys. Acta 1841, 353-361
    • (2014) Biochim. Biophys. Acta , vol.1841 , pp. 353-361
    • Elias, P.M.1    Williams, M.L.2    Choi, E.H.3    Feingold, K.R.4
  • 16
    • 78650206443 scopus 로고    scopus 로고
    • Vitamin D: An ancient hormone
    • Bikle, D. D. (2011) Vitamin D: an ancient hormone. Exp. Dermatol. 20, 7-13
    • (2011) Exp. Dermatol. , vol.20 , pp. 7-13
    • Bikle, D.D.1
  • 17
    • 0037302906 scopus 로고    scopus 로고
    • Vitamin D: A millenium perspective
    • DOI 10.1002/jcb.10338
    • Holick, M. F. (2003) Vitamin D: a millenium perspective. J. Cell. Biochem. 88, 296-307 (Pubitemid 36119902)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.2 , pp. 296-307
    • Holick, M.F.1
  • 18
    • 84875210254 scopus 로고    scopus 로고
    • Nuclear hormone receptor functions in keratinocyte and melanocyte homeostasis, epidermal carcinogenesis and melanomagenesis
    • Hyter, S., and Indra, A. K. (2013) Nuclear hormone receptor functions in keratinocyte and melanocyte homeostasis, epidermal carcinogenesis and melanomagenesis. FEBS Lett. 587, 529-541
    • (2013) FEBS Lett. , vol.587 , pp. 529-541
    • Hyter, S.1    Indra, A.K.2
  • 19
    • 42949178186 scopus 로고    scopus 로고
    • Thematic review series: Skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology
    • Schmuth, M., Jiang, Y. J., Dubrac, S., Elias, P. M., and Feingold, K. R. (2008) Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology. J. Lipid Res. 49, 499-509
    • (2008) J. Lipid Res. , vol.49 , pp. 499-509
    • Schmuth, M.1    Jiang, Y.J.2    Dubrac, S.3    Elias, P.M.4    Feingold, K.R.5
  • 20
    • 79960863632 scopus 로고    scopus 로고
    • The vitamin D receptor: A tumor suppressor in skin
    • Bikle, D. D. (2011) The vitamin D receptor: a tumor suppressor in skin. Discov. Med. 11, 7-17
    • (2011) Discov. Med. , vol.11 , pp. 7-17
    • Bikle, D.D.1
  • 21
    • 13244267262 scopus 로고    scopus 로고
    • The cutaneous serotoninergic/melatoninergic system: Securing a place under the sun
    • DOI 10.1096/fj.04-2079rev
    • Slominski, A., Wortsman, J., and Tobin, D. J. (2005) The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J. 19, 176-194 (Pubitemid 40189259)
    • (2005) FASEB Journal , vol.19 , Issue.2 , pp. 176-194
    • Slominski, A.1    Wortsman, J.2    Tobin, D.J.3
  • 22
    • 0028920392 scopus 로고
    • Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand
    • Wiesenberg, I., Missbach, M., Kahlen, J. P., Schrader, M., and Carlberg, C. (1995) Transcriptional activation of the nuclear receptor RZR alpha by the pineal gland hormone melatonin and identification of CGP 52608 as a synthetic ligand. Nucleic Acids Res. 23, 327-333
    • (1995) Nucleic Acids Res. , vol.23 , pp. 327-333
    • Wiesenberg, I.1    Missbach, M.2    Kahlen, J.P.3    Schrader, M.4    Carlberg, C.5
  • 25
    • 26444588698 scopus 로고    scopus 로고
    • A role of melatonin in neuroectodermal-mesodermal interactions: The hair follicle synthesizes melatonin and expresses functional melatonin receptors
    • DOI 10.1096/fj.04-2293fje
    • Kobayashi, H., Kromminga, A., Dunlop, T. W., Tychsen, B., Conrad, F., Suzuki, N., Memezawa, A., Bettermann, A., Aiba, S., Carlberg, C., and Paus, R. (2005) A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors. FASEB J. 19, 1710-1712 (Pubitemid 41429538)
    • (2005) FASEB Journal , vol.19 , Issue.12 , pp. 1710-1712
    • Kobayashi, H.1    Kromminga, A.2    Dunlop, T.W.3    Tychsen, B.4    Conrad, F.5    Suzuki, N.6    Memezawa, A.7    Bettermann, A.8    Aiba, S.9    Carlberg, C.10    Paus, R.11
  • 28
    • 78649697894 scopus 로고    scopus 로고
    • Vitamin D, disease and therapeutic opportunities
    • Plum, L. A., and DeLuca, H. F. (2010) Vitamin D, disease and therapeutic opportunities. Nat. Rev. Drug Discov. 9, 941-955
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 941-955
    • Plum, L.A.1    Deluca, H.F.2
  • 30
    • 84906790954 scopus 로고    scopus 로고
    • Fundamentals of vitamin D hormone-regulated gene expression
    • [E-pub ahead of print] doi: 10.1016/j.jsbmb.2013.11.004
    • Pike, J. W., and Meyer, M. B. (2013) Fundamentals of vitamin D hormone-regulated gene expression. [E-pub ahead of print] J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2013.11.004
    • (2013) J. Steroid Biochem. Mol. Biol
    • Pike, J.W.1    Meyer, M.B.2
  • 32
    • 23844472962 scopus 로고    scopus 로고
    • The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism
    • DOI 10.1111/j.1742-4658.2005.04819.x
    • Slominski, A., Semak, I., Zjawiony, J., Wortsman, J., Li, W., Szczesniewski, A., and Tuckey, R. C. (2005) The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism. FEBS J. 272, 4080-4090 (Pubitemid 41160916)
    • (2005) FEBS Journal , vol.272 , Issue.16 , pp. 4080-4090
    • Slominski, A.1    Semak, I.2    Zjawiony, J.3    Wortsman, J.4    Li, W.5    Szczesniewski, A.6    Tuckey, R.C.7
  • 33
    • 33745199177 scopus 로고    scopus 로고
    • An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-medi-ated conversion to 20-hydroxyvitamin D2 and 17, 20-dihydroxyvi-tamin D2
    • Slominski, A., Semak, I., Wortsman, J., Zjawiony, J., Li, W., Zbytek, B., and Tuckey, R. C. (2006) An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-medi-ated conversion to 20-hydroxyvitamin D2 and 17, 20-dihydroxyvi-tamin D2. FEBS J. 273, 2891-2901
    • (2006) FEBS J. , vol.273 , pp. 2891-2901
    • Slominski, A.1    Semak, I.2    Wortsman, J.3    Zjawiony, J.4    Li, W.5    Zbytek, B.6    Tuckey, R.C.7
  • 34
    • 42649085358 scopus 로고    scopus 로고
    • Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc
    • DOI 10.1111/j.1742-4658.2008.06406.x
    • Tuckey, R. C., Li, W., Zjawiony, J. K., Zmijewski, M. A., Nguyen, M. N., Sweatman, T., Miller, D., and Slominski, A. (2008) Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc. FEBS J. 275, 2585-2596 (Pubitemid 351600097)
    • (2008) FEBS Journal , vol.275 , Issue.10 , pp. 2585-2596
    • Tuckey, R.C.1    Li, W.2    Zjawiony, J.K.3    Zmijewski, M.A.4    Nguyen, M.N.5    Sweatman, T.6    Miller, D.7    Slominski, A.8
  • 37
    • 84906790378 scopus 로고    scopus 로고
    • The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions
    • [E-pub ahead of print] doi: 10.1016/j.jsbmb.2013.10.012
    • Slominski, A. T., Kim, T. K., Li, W., Yi, A. K., Postlethwaite, A., and Tuckey, R. C. (2013) The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions. [E-pub ahead of print] J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2013.10.012
    • (2013) J. Steroid Biochem. Mol. Biol
    • Slominski, A.T.1    Kim, T.K.2    Li, W.3    Yi, A.K.4    Postlethwaite, A.5    Tuckey, R.C.6
  • 43
    • 84873733072 scopus 로고    scopus 로고
    • Expression of the vitamin D-activating enzyme 1alpha-hydroxylase (CYP27B1) decreases during melanoma progression
    • Brozyna, A. A., Jozwicki, W., Janjetovic, Z., and Slominski, A. T. (2013) Expression of the vitamin D-activating enzyme 1alpha-hydroxylase (CYP27B1) decreases during melanoma progression. Hum. Pathol. 44, 374-387
    • (2013) Hum. Pathol. , vol.44 , pp. 374-387
    • Brozyna, A.A.1    Jozwicki, W.2    Janjetovic, Z.3    Slominski, A.T.4
  • 44
    • 79954576002 scopus 로고    scopus 로고
    • Expression of vitamin D receptor decreases during progression of pigmented skin lesions
    • Brozyna, A. A., Jozwicki, W., Janjetovic, Z., and Slominski, A. T. (2011) Expression of vitamin D receptor decreases during progression of pigmented skin lesions. Hum. Pathol. 42, 618-631
    • (2011) Hum. Pathol. , vol.42 , pp. 618-631
    • Brozyna, A.A.1    Jozwicki, W.2    Janjetovic, Z.3    Slominski, A.T.4
  • 46
    • 84882248309 scopus 로고    scopus 로고
    • Ultraviolet radiation regulates cortisol activity in a waveband-dependent manner in human skin ex vivo
    • Skobowiat, C., Sayre, R. M., Dowdy, J. C., and Slominski, A. T. (2013) Ultraviolet radiation regulates cortisol activity in a waveband-dependent manner in human skin ex vivo. Br. J. Dermatol. 168, 595-601
    • (2013) Br. J. Dermatol. , vol.168 , pp. 595-601
    • Skobowiat, C.1    Sayre, R.M.2    Dowdy, J.C.3    Slominski, A.T.4
  • 48
    • 0035238364 scopus 로고    scopus 로고
    • The ROR nuclear orphan receptor subfamily: Critical regulators of multiple biological processes
    • PII S0079660301690482
    • Jetten, A. M., Kurebayashi, S., and Ueda, E. (2001) The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes. Prog. Nucleic Acids Res. Mol. Biol. 69, 205-247 (Pubitemid 33804679)
    • (2001) Progress in Nucleic Acid Research and Molecular Biology , vol.69 , pp. 205-247
    • Jetten, A.M.1    Kurebayashi, S.2    Ueda, E.3
  • 49
    • 84881488679 scopus 로고    scopus 로고
    • Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors alpha-and gamma-mediated transactivation
    • Takeda, Y., and Jetten, A. M. (2013) Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors alpha-and gamma-mediated transactivation. Nucleic Acids Res. 41, 6992-7008
    • (2013) Nucleic Acids Res. , vol.41 , pp. 6992-7008
    • Takeda, Y.1    Jetten, A.M.2
  • 50
    • 63849125216 scopus 로고    scopus 로고
    • Metabolism of vitamin d2 to 17, 20, 24-trihydroxyvitamin d2 by cytochrome p450scc (CYP11A1)
    • Nguyen, M. N., Slominski, A., Li, W., Ng, Y. R., and Tuckey, R. C. (2009) Metabolism of vitamin d2 to 17, 20, 24-trihydroxyvitamin d2 by cytochrome p450scc (CYP11A1). Drug Metab. Dispos. 37, 761-767
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 761-767
    • Nguyen, M.N.1    Slominski, A.2    Li, W.3    Ng, Y.R.4    Tuckey, R.C.5
  • 53
    • 75749106644 scopus 로고    scopus 로고
    • 20, 23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes
    • Janjetovic, Z., Tuckey, R. C., Nguyen, M. N., Thorpe, E. M., Jr., and Slominski, A. T. (2010) 20, 23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes. J. Cell. Physiol. 223, 36-48
    • (2010) J. Cell. Physiol. , vol.223 , pp. 36-48
    • Janjetovic, Z.1    Tuckey, R.C.2    Nguyen, M.N.3    Thorpe, Jr.E.M.4    Slominski, A.T.5
  • 55
    • 27144468030 scopus 로고    scopus 로고
    • Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization
    • DOI 10.1038/labinvest.3700303, PII 3700303
    • Antonov, J., Goldstein, D. R., Oberli, A., Baltzer, A., Pirotta, M., Fleischmann, A., Altermatt, H. J., and Jaggi, R. (2005) Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization. Lab. Invest. 85, 1040-1050 (Pubitemid 41486428)
    • (2005) Laboratory Investigation , vol.85 , Issue.8 , pp. 1040-1050
    • Antonov, J.1    Goldstein, D.R.2    Oberli, A.3    Baltzer, A.4    Pirotta, M.5    Fleischmann, A.6    Altermatt, H.J.7    Jaggi, R.8
  • 57
    • 79961173585 scopus 로고    scopus 로고
    • Synthesis and antiprolif-erative activity of novel 2-aryl-4-benzoyl- imidazole derivatives targeting tubulin polymerization
    • Chen, J., Li, C. M., Wang, J., Ahn, S., Wang, Z., Lu, Y., Dalton, J. T., Miller, D. D., and Li, W. (2011) Synthesis and antiprolif-erative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization. Bioorg. Med. Chem. 19, 4782-4795
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 4782-4795
    • Chen, J.1    Li, C.M.2    Wang, J.3    Ahn, S.4    Wang, Z.5    Lu, Y.6    Dalton, J.T.7    Miller, D.D.8    Li, W.9
  • 58
    • 0030631403 scopus 로고    scopus 로고
    • Minireview: Collagen-induced arthritis, an animal model of autoimmunity
    • DOI 10.1016/S0024-3205(97)00480-3, PII S0024320597004803
    • Myers, L. K., Rosloniec, E. F., Cremer, M. A., and Kang, A. H. (1997) Collagen-induced arthritis, an animal model of autoim-munity. Life Sci. 61, 1861-1878 (Pubitemid 27461519)
    • (1997) Life Sciences , vol.61 , Issue.19 , pp. 1861-1878
    • Myers, L.K.1    Rosloniec, E.F.2    Cremer, M.A.3    Kang, A.H.4
  • 59
    • 0036134861 scopus 로고    scopus 로고
    • Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model
    • Brand, D. D., Myers, L. K., Whittington, K. B., Latham, K. A., Stuart, J. M., Kang, A. H., and Rosloniec, E. F. (2002) Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model. J. Immunol. 168, 490-498 (Pubitemid 34014153)
    • (2002) Journal of Immunology , vol.168 , Issue.1 , pp. 490-498
    • Brand, D.D.1    Myers, L.K.2    Whittington, K.B.3    Latham, K.A.4    Stuart, J.M.5    Kang, A.H.6    Rosloniec, E.F.7
  • 60
    • 79959401969 scopus 로고    scopus 로고
    • Retinoic acid-related orphan receptor gamma directly regulates neuronal PAS domain protein 2 transcription in vivo
    • Takeda, Y., Kang, H. S., Angers, M., and Jetten, A. M. (2011) Retinoic acid-related orphan receptor gamma directly regulates neuronal PAS domain protein 2 transcription in vivo. Nucleic Acids Res. 39, 4769-4782
    • (2011) Nucleic Acids Res. , vol.39 , pp. 4769-4782
    • Takeda, Y.1    Kang, H.S.2    Angers, M.3    Jetten, A.M.4
  • 61
    • 84884245766 scopus 로고    scopus 로고
    • Role of Th17 cells in skin inflammation of allergic contact dermatitis
    • Peiser, M. (2013) Role of Th17 cells in skin inflammation of allergic contact dermatitis. Clin. Dev. Immunol. 2013, 261037.
    • (2013) Clin. Dev. Immunol. , vol.2013 , pp. 261037
    • Peiser, M.1
  • 64
    • 78651407519 scopus 로고    scopus 로고
    • Lineage-specific effects of 1, 25-dihydroxyvitamin D(3) on the development of effector CD4 T cells
    • Palmer, M. T., Lee, Y. K., Maynard, C. L., Oliver, J. R., Bikle, D. D., Jetten, A. M., and Weaver, C. T. (2011) Lineage-specific effects of 1, 25-dihydroxyvitamin D(3) on the development of effector CD4 T cells. J. Biol. Chem. 286, 997-1004
    • (2011) J. Biol. Chem. , vol.286 , pp. 997-1004
    • Palmer, M.T.1    Lee, Y.K.2    Maynard, C.L.3    Oliver, J.R.4    Bikle, D.D.5    Jetten, A.M.6    Weaver, C.T.7
  • 65
    • 0033670390 scopus 로고    scopus 로고
    • Gene regulation by melatonin
    • Carlberg, C. (2000) Gene regulation by melatonin. Ann. N. Y. Acad. Sci. 917, 387-396
    • (2000) Ann. N. Y. Acad. Sci. , vol.917 , pp. 387-396
    • Carlberg, C.1
  • 66
    • 33749327295 scopus 로고    scopus 로고
    • Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines
    • Fischer, T. W., Zmijewski, M. A., Zbytek, B., Sweatman, T. W., Slominski, R. M., Wortsman, J., and Slominski, A. (2006) Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines. Int. J. Oncol. 29, 665-672
    • (2006) Int. J. Oncol. , vol.29 , pp. 665-672
    • Fischer, T.W.1    Zmijewski, M.A.2    Zbytek, B.3    Sweatman, T.W.4    Slominski, R.M.5    Wortsman, J.6    Slominski, A.7
  • 67
    • 84865330073 scopus 로고    scopus 로고
    • Structure and function of the stratum corneum extracellular matrix
    • Elias, P. M. (2012) Structure and function of the stratum corneum extracellular matrix. J. Invest. Dermatol. 132, 2131-2133
    • (2012) J. Invest. Dermatol. , vol.132 , pp. 2131-2133
    • Elias, P.M.1
  • 69
    • 84880852248 scopus 로고    scopus 로고
    • The retinoid-related orphan receptor RORalpha promotes ker-atinocyte differentiation via FOXN1
    • Dai, J., Brooks, Y., Lefort, K., Getsios, S., and Dotto, G. P. (2013) The retinoid-related orphan receptor RORalpha promotes ker-atinocyte differentiation via FOXN1. PLoS One 8, e70392
    • (2013) PLoS One , vol.8
    • Dai, J.1    Brooks, Y.2    Lefort, K.3    Getsios, S.4    Dotto, G.P.5
  • 70
    • 34447514029 scopus 로고    scopus 로고
    • Vitamin D deficiency
    • Holick, M. F. (2007) Vitamin D deficiency. N. Engl. J. Med. 357, 266-281
    • (2007) N. Engl. J. Med. , vol.357 , pp. 266-281
    • Holick, M.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.