The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions

Journal of Steroid Biochemistry and Molecular Biology

Volumn 144, Issue PART A, 2014, Pages 28-39

  Slominski, Andrzej T ^a,b   Kim, Tae Kang ^a   Li, Wei ^c   Yi, Ae Kyung ^c   Postlethwaite, Arnold ^b,d   Tuckey, Robert C ^e  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Department of Medicine   (United States)

^c Department of Pharmaceutical Sciences ^*  (United States)

^d Veterans Administration   (United States)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

CYP11A1; Epidermis; Immune system; Keratinocytes; P450scc; Vitamin D

Indexed keywords

7 DEHYDROCHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); COLECALCIFEROL; ERGOSTEROL; I KAPPA B; INTERLEUKIN 6; SECOSTEROID; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TUMOR NECROSIS FACTOR ALPHA; ERGOCALCIFEROL; VITAMIN D;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; COLONY FORMATION; CRYSTAL STRUCTURE; CYTOKINE PRODUCTION; DNA SYNTHESIS; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; IMMUNOSTIMULATION; KERATINOCYTE; NUCLEAR MAGNETIC RESONANCE; PERITONEUM MACROPHAGE; ROLE PLAYING; SKIN CELL; SKIN FUNCTION; SOLID TUMOR; ULTRAVIOLET RADIATION; VITAMIN D METABOLISM; EPIDERMIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LEUKEMIA; MELANOCYTE; MELANOMA; NONHUMAN; PROTEIN EXPRESSION; REVIEW; STEROID METABOLISM; ULTRAVIOLET A RADIATION; VITAMIN METABOLISM;

CYP11A1; EPIDERMIS; IMMUNE SYSTEM; KERATINOCYTES; P450SCC; VITAMIN D;

ANIMALS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; EPIDERMIS; HUMANS; SECOSTEROIDS; VITAMIN D; VITAMINS;

EID: 84906790378     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.10.012     Document Type: Review

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