Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 26, 2014, Pages

  Nguyen, Hoai Nghia ^a   Yang, Jr Ming ^a   Afkari, Yashar ^a   Park, Ben Ho ^b   Sesaki, Hiromi ^a   Devreotes, Peter N ^a   Iijima, Miho ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Chemotaxis; Membrane localization; PI3 kinase signaling; Protein engineering; Protein interaction

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DICTYOSTELIUM; FEASIBILITY STUDY; HUMAN; HUMAN CELL; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN PHOSPHORYLATION;

CHEMOTAXIS; MEMBRANE LOCALIZATION; PI3 KINASE SIGNALING; PROTEIN ENGINEERING; PROTEIN INTERACTION;

CELLS, CULTURED; CLONING, MOLECULAR; DICTYOSTELIUM; GENE LIBRARY; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; MUTAGENESIS; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN ENGINEERING; PTEN PHOSPHOHYDROLASE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84903695598     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1409433111     Document Type: Article

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