Characterization, mechanism of anticoagulant action, and assessment of therapeutic potential of a fibrinolytic serine protease (Brevithrombolase) purified from Brevibacillus brevis strain FF02B

Biochimie

Volumn 103, Issue 1, 2014, Pages 50-60

  Majumdar, Sourav ^a   Sarmah, Biplob ^a   Gogoi, Debananda ^a   Banerjee, Subhamoy ^b   Ghosh, Siddhartha S ^b   Banarjee, Subham ^c   Chattopadhyay, Pronobesh ^c   Mukherjee, Ashis K ^a,d  

^a TEZPUR UNIVERSITY   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY GUWAHATI   (India)

^c Defence R D Organization   (India)

^d UNIVERSITY OF NORTHERN COLORADO   (United States)

Author keywords

Anticoagulant; Brevibacillus brevis; Plasmin like fibrinolytic protease; Thrombin degradation; Thrombolytic drug

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN III; BREVITHROMBOLASE; CASEIN; CHROMOGENIC SUBSTRATE; FIBRINOGEN; GLOBULIN; HEPARIN; HYDROLASE; PLASMIN; SERINE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; STREPTOKINASE; UNCLASSIFIED DRUG; WARFARIN; AMIDE; BLOOD CLOTTING FACTOR 10A; THROMBIN;

ALPHA HELIX; AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; BREVIBACILLUS BREVIS; CATALYSIS; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG POTENCY; ENZYMATIC DEGRADATION; HELA CELL LINE; HEMOLYSIS; HT 29 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LETHALITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN SECONDARY STRUCTURE; RAT; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; BOVINAE; BREVIBACILLUS; CHEMISTRY; DISSEMINATED INTRAVASCULAR COAGULATION; DRUG EFFECTS; ENZYMOLOGY; FIBRINOLYSIS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; SEQUENCE ANALYSIS; TOXICITY;

AMIDES; AMINO ACID SEQUENCE; ANIMALS; ANTICOAGULANTS; BREVIBACILLUS; CATTLE; DISSEMINATED INTRAVASCULAR COAGULATION; FACTOR XA; FIBRINOLYSIS; HELA CELLS; HT29 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; RATS; SEQUENCE ANALYSIS; SERINE PROTEASES; THROMBIN;

EID: 84903625161     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.04.002     Document Type: Article

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