The secretory deficit in islets from db/db mice is mainly due to a loss of responding beta cells

Diabetologia

Volumn 57, Issue 7, 2014, Pages 1400-1409

  Do, Oanh H ^a   Low, Jiun T ^a   Gaisano, Herbert Y ^b   Thorn, Peter ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

db db; Insulin; Islet secretion

Indexed keywords

CALCIUM; GLUCOSE; IONOMYCIN; SOLUBLE N ETHYLMALEIMIDE SENSITIVE FACTOR ATTACHMENT PROTEIN; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN 1A; INSULIN; SNARE PROTEIN;

ACIDIFICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL LOSS; CELL MEMBRANE; CELLULAR SECRETION; CONTROLLED STUDY; DIABETES MELLITUS; ENDOCYTOSIS; EXOCYTOSIS; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; MICROSCOPY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PH; PHENOTYPE; PRIORITY JOURNAL; WEIGHT GAIN; ANIMAL; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PATHOPHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; CALCIUM; DIABETES MELLITUS, TYPE 2; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; SNARE PROTEINS;

EID: 84903547080     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3226-8     Document Type: Article

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