Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms

Cell Metabolism

Volumn 12, Issue 6, 2010, Pages 619-632

  Kaneko, Kazuma ^a   Ueki, Kohjiro ^a,b   Takahashi, Noriko ^b   Hashimoto, Shinji ^a   Okamoto, Masayuki ^a   Awazawa, Motoharu ^a   Okazaki, Yukiko ^a   Ohsugi, Mitsuru ^a   Inabe, Kazunori ^a   Umehara, Toshihiro ^a   Yoshida, Masashi ^c   Kakei, Masafumi ^c   Kitamura, Tadahiro ^d   Luo, Ji ^e   Kulkarni, Rohit N ^e   Kahn, C Ronald ^e   Kasai, Haruo ^b   Cantley, Lewis C ^e   Kadowaki, Takashi ^a,f  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

^d GUNMA UNIVERSITY   (Japan)

^e HARVARD MEDICAL SCHOOL   (United States)

^f NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SNARE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL SYNCHRONIZATION; CONTROLLED STUDY; ENZYME INHIBITION; EXOCYTOSIS; GLUCOSE INTOLERANCE; INSULIN RELEASE; KNOCKOUT MOUSE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANIMALS; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; DIABETES MELLITUS, TYPE 2; EXOCYTOSIS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SNARE PROTEINS;

MUS;

EID: 78649509789     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2010.11.005     Document Type: Article

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