Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats

Journal of General Physiology

Volumn 129, Issue 6, 2007, Pages 493-508

  Rose, Tobias ^a,c   Efendic, Suad ^b   Rupnik, Marjan ^a,d  

^a EUROPEAN NEUROSCIENCE INSTITUTE   (Germany)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^d UNIVERSITY OF MARIBOR   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLUCOSE; INSULIN; ISOENZYME; PROTEIN KINASE C; BISINDOLYLMALEIMIDE I; CALCIUM CHANNEL; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CELL STIMULATION; CONTROLLED STUDY; EXOCYTOSIS; GLUCOSE HOMEOSTASIS; GOTO KAKIZAKI RAT; INSULIN RELEASE; MALE; MEMBRANE VESICLE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; RAT; ANIMAL; CELL ENLARGEMENT; CELL MEMBRANE POTENTIAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ELECTRIC CAPACITANCE; ELECTROSTIMULATION; IN VITRO STUDY; METABOLISM; PANCREAS ISLET; PATCH CLAMP; PATHOLOGY; PATHOPHYSIOLOGY; SECRETION; SECRETORY VESICLE; WISTAR RAT;

ANIMALS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL ENLARGEMENT; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ELECTRIC CAPACITANCE; ELECTRIC STIMULATION; EXOCYTOSIS; GLUCOSE; INDOLES; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MALEIMIDES; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, WISTAR; SECRETORY VESICLES;

EID: 34249781153     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200609604     Document Type: Article

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