Expanding Flp-RMCE options: The potential of Recombinase Mediated Twin-Site Targeting (RMTT)

Gene

Volumn 546, Issue 2, 2014, Pages 135-144

  Turan, Soeren ^a,b   Qiao, Junhua ^c   Madden, Sally ^d   Benham, Craig ^e   Kotz, Marina ^a   Schambach, Axel ^a,f   Bode, Juergen ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WUXI APPTEC   (China)

^d Pulmonary and Critical Care Medicine   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

FRT twin sites; Genomic safe harbors (GSH); Genomic scout functions; Recombinase Mediated Cassette Exchange (RMCE); Stress Induced Duplex Destabilization (SIDD)

Indexed keywords

LENTIVIRUS VECTOR; MICRORNA; NAKED DNA; RECOMBINASE; RETROVIRUS VECTOR; RNA POLYMERASE;

CHROMATIN; CHROMOSOME; CHROMOSOME 7; CLONE; CPG ISLAND; DNA METHYLATION; DNA STRAND; DNA STRUCTURE; GENE CASSETTE; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENETIC REGULATION; GENOME; HUMAN; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; INTRON; LONG TERMINAL REPEAT; LOXP SITE; MURINE LEUKEMIA VIRUS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; RECOMBINASE MEDIATED TWIN SITE TARGETING; REPORTER GENE; REVERSE TRANSCRIPTION; REVIEW; TARGET CELL; TRANSCRIPTION INITIATION SITE; TRANSPOSON; YEAST; CELL LINE; GENE; GENE TARGETING; GENE VECTOR; HOST; RECOMBINASE MEDIATED CASSETTE EXCHANGE;

FRT TWIN-SITES; GENOMIC SAFE HARBORS (GSH); GENOMIC SCOUT FUNCTIONS; RECOMBINASE MEDIATED CASSETTE EXCHANGE (RMCE); STRESS-INDUCED DUPLEX DESTABILIZATION (SIDD);

DNA NUCLEOTIDYLTRANSFERASES; GENE TARGETING; GENETIC VECTORS; SACCHAROMYCES CEREVISIAE; TERMINAL REPEAT SEQUENCES; TRANSDUCTION, GENETIC;

EID: 84903533876     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.06.002     Document Type: Review

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