Modified lentiviral LTRs Allow Flp recombinase-mediated cassette exchange and in vivo tracing of "factor-free" induced pluripotent stem cells

Molecular Therapy

Volumn 22, Issue 5, 2014, Pages 919-928

  Kuehle, Johannes ^a   Turan, Soeren ^a   Cantz, Tobias ^a   Hoffmann, Dirk ^a   Suerth, Julia D ^a   Maetzig, Tobias ^a   Zychlinski, Daniela ^a   Klein, Christoph ^b   Steinemann, Doris ^a   Baum, Christopher ^a   Bode, Juergen ^a   Schambach, Axel ^a,c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; LENTIVIRUS VECTOR; MESSENGER RNA; RECOMBINASE; DNA POLYMERASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CLONING VECTOR; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENHANCER REGION; EPIGENETICS; FEMALE; FIBROBLAST; GENE CASSETTE; GENE EXPRESSION; GENE LOCUS; IN VIVO STUDY; LONG TERMINAL REPEAT; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; PROTEIN TRANSPORT; SEQUENCE ANALYSIS; TERATOMA; TRANSGENE; ANIMAL; BIOLOGICAL THERAPY; GENE VECTOR; GENETICS; LENTIVIRINAE; NUCLEAR REPROGRAMMING;

MURINAE; MUS;

ANIMALS; CELL DIFFERENTIATION; CELL- AND TISSUE-BASED THERAPY; CELLULAR REPROGRAMMING; DNA METHYLATION; DNA NUCLEOTIDYLTRANSFERASES; GENETIC VECTORS; INDUCED PLURIPOTENT STEM CELLS; LENTIVIRUS; MICE; TERMINAL REPEAT SEQUENCES;

EID: 84899925923     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.4     Document Type: Article

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