MutLα heterodimers modify the molecular phenotype of Friedreich ataxia

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Ezzatizadeh, Vahid ^a,b   Sandi, Chiranjeevi ^a,c   Sandi, Madhavi ^a   Anjomani Virmouni, Sara ^a   Al Mahdawi, Sahar ^a   Pook, Mark A ^a  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b ROYAN INSTITUTE FOR REPRODUCTIVE BIOMEDICINE   (Iran)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MUTL; PROTEIN MUTL ALPHA; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; FRATAXIN; IRON BINDING PROTEIN; MLH1 PROTEIN, MOUSE; MUTLALPHA PROTEIN, HUMAN; NUCLEAR PROTEIN; PMS2 PROTEIN, MOUSE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA STRUCTURE; DOWN REGULATION; FRIEDREICH ATAXIA; FXN GENE; GENE; GENE SEQUENCE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; DEFICIENCY; DIMERIZATION; GENETIC TRANSCRIPTION; GENETICS; GENOMIC INSTABILITY; HCT116 CELL LINE; KNOCKOUT MOUSE; METABOLISM; MISMATCH REPAIR; PATHOLOGY; TRINUCLEOTIDE REPEAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; ANIMALS; CELL LINE; DIMERIZATION; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FRIEDREICH ATAXIA; GENOMIC INSTABILITY; HCT116 CELLS; HUMANS; IRON-BINDING PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NUCLEAR PROTEINS; PHENOTYPE; TRANSCRIPTION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84903516149     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100523     Document Type: Article

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