Degree of glutathione deficiency and redox imbalance depend on subtype of mitochondrial disease and clinical status

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Enns, Gregory M ^a   Moore, Tereza ^b   Le, Anthony ^b   Atkuri, Kondala ^a   Shah, Monisha K ^a   Cusmano Ozog, Kristina ^a,c   Niemi, Anna Kaisa ^a   Cowan, Tina M ^b  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; GLUTATHIONE DISULFIDE; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; ARTICLE; CEREBROVASCULAR ACCIDENT; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON TRANSPORT CHAIN ABNORMALITY; FEMALE; GLUTATHIONE DEFICIENCY; HOSPITALIZATION; HUMAN; INFANT; LACTIC ACIDOSIS; LEIGH DISEASE; MAJOR CLINICAL STUDY; MALE; MELAS SYNDROME; MITOCHONDRIAL DNA DELETION SYNDROME; MITOCHONDRIAL DNA DEPLETION SYNDROME; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL ENCEPHALOMYOPATHY; OXIDATION REDUCTION POTENTIAL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN DEFICIENCY; REDOX IMBALANCE; TANDEM MASS SPECTROMETRY; BLOOD; CASE CONTROL STUDY; CLASSIFICATION; METABOLISM; MIDDLE AGED; MITOCHONDRION; OXIDATION REDUCTION REACTION; PATHOLOGY; PRESCHOOL CHILD; SEVERITY OF ILLNESS INDEX;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; INFANT; MALE; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL DISEASES; OXIDATION-REDUCTION; OXIDATIVE STRESS; SEVERITY OF ILLNESS INDEX; TANDEM MASS SPECTROMETRY;

EID: 84903398952     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100001     Document Type: Article

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