Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation

Biochemical Journal

Volumn 391, Issue 2, 2005, Pages 191-202

  Sandhu, Jagdeep K ^a   Sodja, Caroline ^a   McRae, Keven ^a   Li, Yan ^a   Rippstein, Peter ^b   Wei, Yau Huei ^c   Lach, Boleslaw ^d   Lee, Fay ^e   Bucurescu, Septimiu ^f   Harper, Mary Ellen ^f   Sikorska, Marianna ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^e HEALTH CANADA   (Canada)

^f UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Caspase independent; Electron transport chain; MELAS; Mitochondrial DNA mutation; Nitric oxide donor; Reactive nitrogen and oxygen species

Indexed keywords

AMINES; DISEASES; DNA; GENES; GENETIC ENGINEERING; METABOLISM; MUTAGENESIS; NITROGEN; NITROGEN OXIDES; OXYGEN; PATHOLOGY; PHYSIOLOGY; TOXICITY;

CASPASE-INDEPENDENT; ELECTRON TRANSPORT CHAIN; MITOCHONDRIAL DNA MUTATION; NITRIC OXIDE DONOR; REACTIVE NITROGEN AND OXYGEN SPECIES;

CYTOLOGY;

AMMONIUM DERIVATIVE; CYTOCHROME C OXIDASE; GLUCOSE; LACTIC ACID; LINSIDOMINE; MITOCHONDRIAL DNA; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; REACTIVE OXYGEN METABOLITE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL DEATH; CELL ENERGY; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYBRID; CYTOTOXICITY; ELECTRON TRANSPORT; ENZYME ACTIVITY; GLIOBLASTOMA; HETEROZYGOSITY; HUMAN; HUMAN CELL; MELAS SYNDROME; MITOCHONDRIAL GENETICS; MITOCHONDRIAL MEMBRANE; NITROSATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SOMATIC MUTATION; WILD TYPE;

ADENOSINE TRIPHOSPHATE; CELL DEATH; CELL SURVIVAL; DNA, MITOCHONDRIAL; HUMANS; HYBRID CELLS; MELAS SYNDROME; MOLSIDOMINE; MUTATION; NITRIC OXIDE DONORS; NITROPRUSSIDE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; TRIAZENES;

EID: 27444447841     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050272     Document Type: Article

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