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Volumn 56, Issue 5, 1998, Pages 645-655

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: Relevance to Parkinson's disease

Author keywords

Apoptosis; Glutathione; Mitochondria; Neuronal cell; Oxidative stress; Parkinson rsquo; s disease

Indexed keywords

DNA FRAGMENT; GLUTATHIONE; LEVODOPA;

EID: 0032169935     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00647-3     Document Type: Article
Times cited : (214)

References (69)
  • 2
    • 0025079961 scopus 로고
    • Parkinson's disease and Alzheimer's disease: Neurodegenerative disorders due to brain antioxidant system deficiency?
    • I. Emerit, L. Packer, & C. Auclair. New York: Plenum Press
    • Ceballos I., Agid F., Delacourte A., Defossez A., Nicole A., Sinet P.M. Parkinson's disease and Alzheimer's disease neurodegenerative disorders due to brain antioxidant system deficiency? Emerit I., Packer L., Auclair C. Advances in Experimental Biology and Medicine. 1990;493-498 Plenum Press, New York.
    • (1990) Advances in Experimental Biology and Medicine , pp. 493-498
    • Ceballos, I.1    Agid, F.2    Delacourte, A.3    Defossez, A.4    Nicole, A.5    Sinet, P.M.6
  • 4
    • 0010245713 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • Landes, & Springer. Georgetown: Landes Company
    • Ceballos-Picot I. Oxidative stress in Parkinson's disease. Landes, Springer. The Role of Oxidative Stress in Neuronal Death. 1997;176-197 Landes Company, Georgetown.
    • (1997) The Role of Oxidative Stress in Neuronal Death , pp. 176-197
    • Ceballos-Picot, I.1
  • 5
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S., Cohen G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol. 32:1992;804-812.
    • (1992) Ann Neurol , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 8
    • 0022415447 scopus 로고
    • Glutathione peroxidase activity in Parkinson's disease brain
    • Kish S.J., Marito C., Hornykiewics O. Glutathione peroxidase activity in Parkinson's disease brain. Neurosci Lett. 58:1985;343-346.
    • (1985) Neurosci Lett , vol.58 , pp. 343-346
    • Kish, S.J.1    Marito, C.2    Hornykiewics, O.3
  • 10
    • 0026694525 scopus 로고
    • Glutathione in Parkinson's disease, A link between oxidative stress and mitochondrial damage?
    • Di Monte D.A., Chan Piu Sandy M.S. Glutathione in Parkinson's disease, A link between oxidative stress and mitochondrial damage? Ann Neurol. 32:1992;S111-S113.
    • (1992) Ann Neurol , vol.32
    • Di Monte, D.A.1    Chan Piu Sandy, M.S.2
  • 11
    • 0028059308 scopus 로고
    • Oxidative damage in neurodegenerative diseases
    • Jenner P. Oxidative damage in neurodegenerative diseases. Lancet. 344:1994;796-798.
    • (1994) Lancet , vol.344 , pp. 796-798
    • Jenner, P.1
  • 12
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • Cleeter M.J.W., Cooper J.M., Schapira A.H.V. Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J Neurochem. 58:1992;786-789.
    • (1992) J Neurochem , vol.58 , pp. 786-789
    • Cleeter, M.J.W.1    Cooper, J.M.2    Schapira, A.H.V.3
  • 13
    • 0022641230 scopus 로고
    • 1-methyl-4-phenylpyridinium is neurotoxic to the nigrostriatal dopamine pathway
    • Marsden C.D., Naylor R.J. 1-methyl-4-phenylpyridinium is neurotoxic to the nigrostriatal dopamine pathway. Nature. 319:1986;56-57.
    • (1986) Nature , vol.319 , pp. 56-57
    • Marsden, C.D.1    Naylor, R.J.2
  • 14
    • 0026718086 scopus 로고
    • Brain skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
    • Mann V.M., Cooper J.M., Krige D., Daniel S.E., Schapira A.H.V., Marsden C.D. Brain skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. Brain. 115:1992;333-342.
    • (1992) Brain , vol.115 , pp. 333-342
    • Mann, V.M.1    Cooper, J.M.2    Krige, D.3    Daniel, S.E.4    Schapira, A.H.V.5    Marsden, C.D.6
  • 15
    • 0028274216 scopus 로고
    • Evidence for mitochondrial dysfunction in Parkinson's disease: A critical appraisal
    • Schapira A.H.V. Evidence for mitochondrial dysfunction in Parkinson's disease: a critical appraisal. Movement Disord. 9:1994;125-138.
    • (1994) Movement Disord , vol.9 , pp. 125-138
    • Schapira, A.H.V.1
  • 16
    • 0028918841 scopus 로고
    • Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine
    • Glinka Y.Y., Youdim M.B.H. Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine. European J Pharmacol. 292:1995;329-332.
    • (1995) European J Pharmacol , vol.292 , pp. 329-332
    • Glinka, Y.Y.1    Youdim, M.B.H.2
  • 17
    • 0029969350 scopus 로고    scopus 로고
    • Nature of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine
    • Glinka Y., Tipton K.F., Youdim M.B.H. Nature of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine. J Neurochem. 66:1996;2004-2010.
    • (1996) J Neurochem , vol.66 , pp. 2004-2010
    • Glinka, Y.1    Tipton, K.F.2    Youdim, M.B.H.3
  • 18
    • 0024264526 scopus 로고
    • Glutathione metabolism and its selective modification
    • Meister A. Glutathione metabolism and its selective modification. J Biol Chem. 263:1988;17205-17208.
    • (1988) J Biol Chem , vol.263 , pp. 17205-17208
    • Meister, A.1
  • 19
    • 0027990215 scopus 로고
    • Apoptosis and necrosis: Intracellular levels of glutathione influence mode of cell death
    • Fernandes R.S., Cotter T.G. Apoptosis and necrosis intracellular levels of glutathione influence mode of cell death . Biochem Pharmacol. 48:1994;675-681.
    • (1994) Biochem Pharmacol , vol.48 , pp. 675-681
    • Fernandes, R.S.1    Cotter, T.G.2
  • 20
    • 0030008721 scopus 로고    scopus 로고
    • Assessment of the role of the glutathione and pentose phosphate pathways in the protection of primary cerebrocortical cultures from oxidative stress
    • Ben-Yoseph O., Boxer P.A., Ross B.D. Assessment of the role of the glutathione and pentose phosphate pathways in the protection of primary cerebrocortical cultures from oxidative stress. J Neurochem. 66:1996;2329-2337.
    • (1996) J Neurochem , vol.66 , pp. 2329-2337
    • Ben-Yoseph, O.1    Boxer, P.A.2    Ross, B.D.3
  • 21
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara J.I., Miura K., Bannai S. Maintenance of neuronal glutathione by glial cells. J Neurochem. 64:1993;1672-1676.
    • (1993) J Neurochem , vol.64 , pp. 1672-1676
    • Sagara, J.I.1    Miura, K.2    Bannai, S.3
  • 22
    • 0029832436 scopus 로고    scopus 로고
    • Glutathione is involved in the granular storage of dopamine in rat PC12 pheochromocytoma cells: Implication for the pathogenesis of Parkinson's disease
    • Drukarch B., Jongenelen C.A.M., Schepens E., Langeveld C.H., Stoof J.C. Glutathione is involved in the granular storage of dopamine in rat PC12 pheochromocytoma cells: implication for the pathogenesis of Parkinson's disease. J Neurosci. 16:1996;6038-6045.
    • (1996) J Neurosci , vol.16 , pp. 6038-6045
    • Drukarch, B.1    Jongenelen, C.A.M.2    Schepens, E.3    Langeveld, C.H.4    Stoof, J.C.5
  • 23
    • 0029817315 scopus 로고    scopus 로고
    • Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion
    • Grasbon-Frodl E.M., Andersson A., Brundin P. Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion. J Neurochem. 67:1996;1653-1660.
    • (1996) J Neurochem , vol.67 , pp. 1653-1660
    • Grasbon-Frodl, E.M.1    Andersson, A.2    Brundin, P.3
  • 24
    • 0029845402 scopus 로고    scopus 로고
    • Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons
    • Andersen J.K., Mo J.Q., Hom D.G., Lee F.Y., Harnish P., Hamill R.W., McNeill T.H. Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons. J Neurochem. 67:1996;2164-2171.
    • (1996) J Neurochem , vol.67 , pp. 2164-2171
    • Andersen, J.K.1    Mo, J.Q.2    Hom, D.G.3    Lee, F.Y.4    Harnish, P.5    Hamill, R.W.6    McNeill, T.H.7
  • 26
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 119:1992;493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 27
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
    • Griffith O. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem. 106:1980;207-212.
    • (1980) Anal Biochem , vol.106 , pp. 207-212
    • Griffith, O.1
  • 28
    • 0029871412 scopus 로고    scopus 로고
    • Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer's type. Place of extracellular glutathione peroxidase
    • Ceballos-Picot I., Merad-Boudia M., Nicole A., Thevenin M., Hellier G., Legrain S., Berr C. Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer's type. Place of extracellular glutathione peroxidase. Free Radical Biol Med. 20:1996;579-587.
    • (1996) Free Radical Biol Med , vol.20 , pp. 579-587
    • Ceballos-Picot, I.1    Merad-Boudia, M.2    Nicole, A.3    Thevenin, M.4    Hellier, G.5    Legrain, S.6    Berr, C.7
  • 29
    • 0029018603 scopus 로고
    • Impairment of the mitochondrial respiratory chain activity in diethylnitrosamine-induced rat hepatomas: Possible involvement of oxygen free radicals
    • Boitier E., Merad-Boudia M., Guguen-Guillouzo C., Defer N., Ceballos-Picot I., Leroux J.P., Marsac C. Impairment of the mitochondrial respiratory chain activity in diethylnitrosamine-induced rat hepatomas: possible involvement of oxygen free radicals. Cancer Res. 55:1995;3028-3035.
    • (1995) Cancer Res , vol.55 , pp. 3028-3035
    • Boitier, E.1    Merad-Boudia, M.2    Guguen-Guillouzo, C.3    Defer, N.4    Ceballos-Picot, I.5    Leroux, J.P.6    Marsac, C.7
  • 30
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • Beal M.F. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol. 38:1995;357-366.
    • (1995) Ann Neurol , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 31
    • 0010288647 scopus 로고
    • Role of free radicals in Alzheimer's disease and Down syndrome
    • L. Packer, A. Philippo, & Y. Christen. Heidelberg: Springer-Verlag
    • Sinet P.M., Ceballos-Picot I. Role of free radicals in Alzheimer's disease and Down syndrome. Packer L., Philippo A., Christen Y. Free Radicals in the Brain. 1992;1-98 Springer-Verlag, Heidelberg.
    • (1992) Free Radicals in the Brain , pp. 1-98
    • Sinet, P.M.1    Ceballos-Picot, I.2
  • 33
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-spartate or nitric oxide/superoxide in cortical cell cultures
    • Bonfoco E., Krainc D., Ankarcrona M., Nicotera P., Lipton S.A. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-spartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA. 92:1995;7162-7166.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 34
    • 0027931558 scopus 로고
    • Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons
    • Whittemore E.R., Loo D.T., Cotman C.W. Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons. Neuroreport. 5:1994;1485-1488.
    • (1994) Neuroreport , vol.5 , pp. 1485-1488
    • Whittemore, E.R.1    Loo, D.T.2    Cotman, C.W.3
  • 35
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy T.H., Miyamoto M., Sastre A., Schnaar R.L., Coyle J.T. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron. 2:1989;1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 36
    • 0028095981 scopus 로고
    • Oxidative stress induces apoptosis in embryonic cortical neurons
    • Ratan R.R., Murphy T.H., Baraban J.M. Oxidative stress induces apoptosis in embryonic cortical neurons. J Neurochem. 62:1994;376-379.
    • (1994) J Neurochem , vol.62 , pp. 376-379
    • Ratan, R.R.1    Murphy, T.H.2    Baraban, J.M.3
  • 37
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
    • Greenlund L.J.S., Deckwerth T.L., Johnson E. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron. 14:1995;303-315.
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.S.1    Deckwerth, T.L.2    Johnson, E.3
  • 40
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen D.E. Neural apoptosis. Ann Neurol. 38:1995;839-851.
    • (1995) Ann Neurol , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 44
    • 0030059868 scopus 로고    scopus 로고
    • L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
    • Han S.-K., Mytilineou C., Cohen G. L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J Neurochem. 66:1996;501-510.
    • (1996) J Neurochem , vol.66 , pp. 501-510
    • Han, S.-K.1    Mytilineou, C.2    Cohen, G.3
  • 45
    • 0030057990 scopus 로고    scopus 로고
    • Age-dependent sensitivity of cultured peripheral sympathetic neurons to 1-methyl-4-phenylpyridinium: Role of glutathione
    • Bhave S.V., Johannessen J.N., Lash L.H., Wakade T.D., Wakade A.R. Age-dependent sensitivity of cultured peripheral sympathetic neurons to 1-methyl-4-phenylpyridinium: role of glutathione. J Neurochem. 67:1996;557-565.
    • (1996) J Neurochem , vol.67 , pp. 557-565
    • Bhave, S.V.1    Johannessen, J.N.2    Lash, L.H.3    Wakade, T.D.4    Wakade, A.R.5
  • 46
    • 0029970588 scopus 로고    scopus 로고
    • Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity
    • Heales S.J.R., Bolanos J.P., Clark J.B. Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity. Neurochem Res. 21:1996;35-39.
    • (1996) Neurochem Res , vol.21 , pp. 35-39
    • Heales, S.J.R.1    Bolanos, J.P.2    Clark, J.B.3
  • 47
    • 0028856368 scopus 로고
    • NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implication for cell death
    • Gunasekar P.G., Khantasamy A.G., Borowitz J.L., Isom G.E. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J Neurochem. 65:1995;2016-2021.
    • (1995) J Neurochem , vol.65 , pp. 2016-2021
    • Gunasekar, P.G.1    Khantasamy, A.G.2    Borowitz, J.L.3    Isom, G.E.4
  • 49
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • Sian J., Dexter D.T., Lees A.J., Daniel S., Agid Y., Javoy-Agid F., Jenner P., Marsden C.D. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol. 36:1994;348-355.
    • (1994) Ann Neurol , vol.36 , pp. 348-355
    • Sian, J.1    Dexter, D.T.2    Lees, A.J.3    Daniel, S.4    Agid, Y.5    Javoy-Agid, F.6    Jenner, P.7    Marsden, C.D.8
  • 50
    • 0026644192 scopus 로고
    • Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease
    • Sofic E., Lange K.W., Jellinger K., Riederer P. Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci Lett. 142:1992;128-130.
    • (1992) Neurosci Lett , vol.142 , pp. 128-130
    • Sofic, E.1    Lange, K.W.2    Jellinger, K.3    Riederer, P.4
  • 51
    • 0022650447 scopus 로고
    • Depletion of glutathione in brainstem of mice by MPTP is prevented by antioxidant treatment
    • Yong V.W., Perry T.L., Krisman A.A. Depletion of glutathione in brainstem of mice by MPTP is prevented by antioxidant treatment. Neurosci Lett. 63:1986;56-60.
    • (1986) Neurosci Lett , vol.63 , pp. 56-60
    • Yong, V.W.1    Perry, T.L.2    Krisman, A.A.3
  • 52
    • 0026720018 scopus 로고
    • Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes
    • Mithofer K., Sandy M.S., Smith S.M., Di Monte D. Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes. Arch Biochem Biophys. 295:1992;132-136.
    • (1992) Arch Biochem Biophys , vol.295 , pp. 132-136
    • Mithofer, K.1    Sandy, M.S.2    Smith, S.M.3    Di Monte, D.4
  • 53
    • 0027349946 scopus 로고
    • Biochemical mechanisms underlying MPTP-induced and idiopathic parkinsonism
    • H. Narabayashi, N. Nagatsu, N. Yanagisawa, & Y. Mizuno. New York: Raven Press
    • Singer T.P., Ramsay R.R., Sonsalla P.K. Biochemical mechanisms underlying MPTP-induced and idiopathic parkinsonism. Narabayashi H., Nagatsu N., Yanagisawa N., Mizuno Y. Advances in Neurology. 1993;300-312 Raven Press, New York.
    • (1993) Advances in Neurology , pp. 300-312
    • Singer, T.P.1    Ramsay, R.R.2    Sonsalla, P.K.3
  • 54
    • 0029033862 scopus 로고
    • Mitochondrial changes associated with glutathione deficiency
    • Meister A. Mitochondrial changes associated with glutathione deficiency. Biochim Biophys Acta. 1271:1995;35-42.
    • (1995) Biochim Biophys Acta , vol.1271 , pp. 35-42
    • Meister, A.1
  • 56
    • 0028799706 scopus 로고
    • Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration
    • Heales S.J.R., Davies S.E.C., Bates T.E., Clark J.B. Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochem Res. 20:1995;31-38.
    • (1995) Neurochem Res , vol.20 , pp. 31-38
    • Heales, S.J.R.1    Davies, S.E.C.2    Bates, T.E.3    Clark, J.B.4
  • 59
    • 0029012812 scopus 로고
    • Age- And peroxidative stress-related modifications of the cerebral enzymatic activites linked to mitochondria and the glutathione system
    • Benzi G., Moretti A. Age- and peroxidative stress-related modifications of the cerebral enzymatic activites linked to mitochondria and the glutathione system. Free Radical Biol Med. 19:1995;77-101.
    • (1995) Free Radical Biol Med , vol.19 , pp. 77-101
    • Benzi, G.1    Moretti, A.2
  • 60
    • 0027435899 scopus 로고
    • Iron-induced oxidative stress and mitochondrial dysfunction: Relevance to Parkinson's disease
    • Hartley A., Cooper J.M., Schapira A.H.V. Iron-induced oxidative stress and mitochondrial dysfunction: relevance to Parkinson's disease. Brain Res. 627:1993;349-353.
    • (1993) Brain Res , vol.627 , pp. 349-353
    • Hartley, A.1    Cooper, J.M.2    Schapira, A.H.V.3
  • 61
    • 0029877396 scopus 로고    scopus 로고
    • Cellular responses of cultured cerebellar astrocytes to ethacrynic acid-induced perturbation of subcellular glutathione homeostasis
    • Huang J., Philbert M.A. Cellular responses of cultured cerebellar astrocytes to ethacrynic acid-induced perturbation of subcellular glutathione homeostasis. Brain Res. 711:1996;184-192.
    • (1996) Brain Res , vol.711 , pp. 184-192
    • Huang, J.1    Philbert, M.A.2
  • 62
    • 84975751684 scopus 로고
    • Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
    • Hartley A., Stone J.M., Heron C., Cooper J.M., Schapira A.H. Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease. J Neurochem. 63:1994;1987-1990.
    • (1994) J Neurochem , vol.63 , pp. 1987-1990
    • Hartley, A.1    Stone, J.M.2    Heron, C.3    Cooper, J.M.4    Schapira, A.H.5
  • 65
    • 0031025395 scopus 로고    scopus 로고
    • Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures
    • Zeewalk G.D., Bernard L.P., Albers D.S., Mirochnitchenko O., Niklas W.J., Sonsalla P.K. Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures. J Neurochem. 68:1997;426-429.
    • (1997) J Neurochem , vol.68 , pp. 426-429
    • Zeewalk, G.D.1    Bernard, L.P.2    Albers, D.S.3    Mirochnitchenko, O.4    Niklas, W.J.5    Sonsalla, P.K.6
  • 66
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarkrona M., Dypbukt J.M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S.A., Nicotera P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarkrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 67
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X., Naekyung C.K., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 86:1996;147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Naekyung, C.K.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 68
    • 0030918062 scopus 로고    scopus 로고
    • Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: Involvement of the glutathione system
    • Hou J.-G., Cohen G., Mytilineou C. Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: involvement of the glutathione system. J Neurochem. 69:1997;76-83.
    • (1997) J Neurochem , vol.69 , pp. 76-83
    • Hou, J.-G.1    Cohen, G.2    Mytilineou, C.3
  • 69
    • 0001547757 scopus 로고
    • Origin and turnover of mitochondrial glutathione
    • Griffith O.W., Meister A. Origin and turnover of mitochondrial glutathione. Proc Natl Acad Sci USA. 82:1985;4668-4672.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4668-4672
    • Griffith, O.W.1    Meister, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.