Migration and differentiation of CD8+ T cells

Immunological Reviews

Volumn 186, Issue , 2002, Pages 221-233

  Weninger, Wolfgang ^a   Manjunath, N ^a   Von Andrian, Ulrich H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN;

ANIMAL MODEL; ANTIGEN PRESENTING CELL; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELL INTERACTION; CELL MIGRATION; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; IMMUNE RESPONSE; INFLAMMATION; LYMPHOID ORGAN; LYMPHOID TISSUE; MEMORY CELL; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; ANIMAL; CD8+ T LYMPHOCYTE; CELL MOTION; CYTOLOGY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; PEYER PATCH;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL MOVEMENT; IMMUNOLOGIC MEMORY; PEYER'S PATCHES; T-LYMPHOCYTE SUBSETS;

EID: 0036697002     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2002.18618.x     Document Type: Review

References (64)

1. von Andrian UH, Mackay CR. T cell function and migration. Two sides of the same coin. N Engl J Med 2000;343:1020-1034.
2. Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nature Rev Immunol 2002;2:251-262.
3. Russell JH, Ley TJ. Lymphocyte-mediated cytotoxicity. Annu Rev Immunol 2002;20:323-370.
4. Price DA, Klenerman P, Booth BL, Phillips RE, Sewell AK. Cytotoxic T lymphocytes, chemokines and antiviral immunity. Immunol Today 1999;20:212-216.
5. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science 1996;272:60-66.
6. Kunkel EJ, Butcher EC. Chemokines and the tissue-specific migration of lymphocytes. Immunity 2002;16:1-4.
7. Sprent J, Surh CD. T cell memory. Annu Rev Immunol 2002;20:551-579.
8. Manjunath N, Shankar P, Stockton B, Dubey PD, Lieberman J, von Andrian UH. A transgenic mouse model to analyze CD8 (+) effector T cell differentiation in vivo. Proc Natl Acad Sci USA 1999;96:13932-13937.
9. Stein JV, et al. The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. J Exp Med 2000;191:61-76.
10. Weninger W, Crowley MA, Manjunath N, von Andrian UH. Migratory properties of naïve, effector, and memory CD8 (+) T cells. J Exp Med 2001;194:953-966.
11. Manjunath N, et al. Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. J Clin Invest 2001;108:871-878.
12. Ellmeier W, Sawada S, Littman DR. The regulation of CD4 and CD8 coreceptor gene expression during T cell development. Annu Rev Immunol 1999;17:523-554.
13. Siu G, Wurster AL, Duncan DD, Soliman TM, Hedrick SM. A transcriptional silencer controls the developmental expression of the CD4 gene. EMBO J 1994;13:3570-3579.
14. Sawada S, Littman DR. Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene. Mol Cell Biol 1991;11:5506-5515.
15. Sawada S, Scarborough JD, Killeen N, Littman DR. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 1994;77:917-929.
16. Marchesi VT, Gowans JL. The migration of lymphocytes through the endothelium of venules in lymph nodes: an electron microscope study. Proc R Soc 1964;B159:283-290.
17. Warnock RA, Askari S, Butcher EC, von Andrian UH. Molecular mechanisms of lymphocyte homing to peripheral lymph nodes. J Exp Med 1998;187:205-216.
18. von Andrian UH, M'Rini C. In situ analysis of lymphocyte migration to lymph nodes. Cell Adhes Commun 1998;6:85-96.
19. Vassileva G, et al. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes. J Exp Med 1999;190:1183-1188.
20. Luther SA, Tang HL, Hyman PL, Farr AG, Cyster JG. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc Natl Acad Sci USA 2000;97:12694-12699.
21. Nakano H, et al. Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes. Eur J Immunol 1997;27:215-221.
22. Palframan RT, et al. Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J Exp Med 2001;194:1361-1374.
23. Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999;401:708-712.
24. Champagne P, et al. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001;410:106-111.
25. Masopust D, Vezys V, Marzo AL, Lefrancois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001;291:2413-2417.
26. Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK. Visualizing the generation of memory CD4 T cells in the whole body. Nature 2001;410:101-105.
27. Waldmann TA, Tagaya Y. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu Rev Immunol 1999;17:19-49.
28. Waldmann TA, Dubois S, Tagaya Y. Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity 2001;14:105-110.
29. Sugamura K, et al. The common gamma-chain for multiple cytokine receptors. Adv Immunol 1995;59:225-277.
30. Asao H, et al. Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol 2001;167:1-5.
31. Grabstein KH, et al. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 1994;264:965-968.
32. Burton JD, et al. A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 1994;91:4935-4939.
33. Bamford RN, et al. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 1994;91:4940-4944.
34. Schorle H, Holtschke T, Hünig T, Schimpl A, Horak I. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 1991;352:621-624.
35. Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, Alt FW. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995;3:521-530.
36. Suzuki H, Duncan GS, Takimoto H, Mak TW. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain. J Exp Med 1997;185:499-505.
37. Suzuki H, Zhou YW, Kato M, Mak TW, Nakashima I. Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo. J Exp Med 1999;190:1561-1572.
38. Kennedy MK, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771-780.
39. Lodolce JP, et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669-676.
40. + T cells in vivo by IL-15. Immunity 1998;8:591-599.
41. + memory T cells by opposing cytokines. Science 2000;288:675-678.
42. + T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells. Nat Immunol 2001;2:415-422.
43. van Stipdonk MJ, Lemmens EE, Schoenberger SP. Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat Immunol 2001;2:423-429.
44. Pircher H, Burki K, Lang R, Hengartner H, Zinkernagel RM. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 1989;342:559-561.
45. Geginat J, Sallusto F, Lanzavecchia A. Cytokine-driven proliferation and differentiation of human naïve, central memory, and effector memory CD4 (+) T cells. J Exp Med 2001;194:1711-1719.
46. Schluns KS, Williams K, Ma A, Zheng XX, Lefrancois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 2002;168:4827-4831.
47. Opferman JT, Ober BT, Ashton-Rickardt PG. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 1999;283:1745-1748.
48. Hu H, Huston G, Duso D, Lepak N, Roman E, Swain SL. CD4 (+) T cell effectors can become memory cells with high efficiency and without further division. Nat Immunol 2001;2:705-710.
49. Jacob J, Baltimore D. Modelling T-cell memory by genetic marking of memory T cells in viva. Nature 1999;399:593-597.
50. Austrup F, et al. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 1997;385:81-83.
51. Xie H, Lim YC, Luscinskas FW, Lichtman AH. Acquisition of selectin binding and peripheral homing properties by CD4 (+) and CD8 (+) T cells. J Exp Med 1999;189:1765-1776.
52. Sallusto F, Lanzavecchia A, Mackay CR. Chemokines and chemokine receptors in T-cell priming and Th1/Th2- mediated responses. Immunol Today 1998;19:568-574.
53. Picker LJ, Butcher EC. Physiological and molecular mechanisms of lymphocyte homing. Annu Rev Immunol 1992;10:561-591.
54. Kantele A, et al. Homing potentials of circulating lymphocytes in humans depend on the site of activation: oral, but not parenteral, typhoid vaccination induces circulating antibody-secreting cells that all bear homing receptors directing them to the gut. J Immunol 1997;158:574-579.
55. Westermann J, Pabst R. How organ-specific is the migration of "naïve" and "memory" T cells? Immunol Today 1996;17:278-282.
56. Davenport MP, Grimm MC, Lloyd AR. A homing selection hypothesis for T-cell trafficking. Immunol Today 2000;21:315-317.
57. Campbell DJ, Butcher EC. Rapid acquisition of tissue-specific homing phenotypes by CD4 (+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med 2002;195:135-141.
58. Fuhlbrigge RC, Kieffer JD, Armerding D, Kupper TS. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature 1997;389:978-981.
59. Campbell J, et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 1999;400:776-780
60. Homey B, et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med 2002;8:157-165.
61. Kunkel EJ, et al. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J Exp Med 2000;192:761-768.
62. Zabel BA, et al. Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med 1999;190:1241-1256.
63. Mackay C. Homing of naïve, memory and effector lymphocytes. Curr Opin Immunol 1993;5:423-427.
64. von Andrian UH. Intravital microscopy of the peripheral lymph node microcirculation in mice. Microcirculation 1996;3:287-300.