The role and regulation of mTOR in T-lymphocyte function

Archivum Immunologiae et Therapiae Experimentalis

Volumn 60, Issue 3, 2012, Pages 173-181

  O'Brien, Thomas F ^a   Zhong, Xiao Ping ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Diacylglycerol kinase; Mammalian target of rapamycin; PI3K Akt; RasGPP1; T lymphocyte; Tuberous sclerosis complex 1

Indexed keywords

DIACYLGLYCEROL KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RAS PROTEIN; RASGRP1 PROTEIN; T LYMPHOCYTE RECEPTOR; TUBEROUS SCLEROSIS COMPLEX 1; UNCLASSIFIED DRUG;

ANTIGEN SPECIFICITY; AUTOIMMUNE DISEASE; CD8+ T LYMPHOCYTE; CELL METABOLISM; CELLULAR IMMUNITY; CLONAL ANERGY; ENZYME ACTIVITY; ENZYME REGULATION; HELPER CELL; HOMEOSTASIS; HUMAN; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MALIGNANT NEOPLASTIC DISEASE; MEMORY CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; CELL DIFFERENTIATION; DIACYLGLYCEROL KINASE; DNA-BINDING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MICE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84863654925     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-012-0171-4     Document Type: Review

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