Multistage unfolding of an SH3 domain: An initial urea-filled dry molten globule precedes a wet molten globule with non-native structure

Journal of Physical Chemistry B

Volumn 118, Issue 24, 2014, Pages 6380-6392

  Dasgupta, Amrita ^a   Udgaonkar, Jayant B ^a   Das, Payel ^b  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^b IBM T J WATSON RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METABOLISM; PROTEINS;

CONFORMATIONAL FLEXIBILITY; HYDROPHOBIC RESIDUES; MOLTEN GLOBULE; NON-NATIVE; PI3-KINASE; PROTEIN CORE; WATER PENETRATION;

UREA;

PHOSPHATIDYLINOSITOL 3 KINASE; UREA; WATER;

AMINO ACID SEQUENCE; CHEMISTRY; KINETICS; MOLECULAR DYNAMICS; MOLECULAR GENETICS; PROTEIN UNFOLDING; SRC HOMOLOGY DOMAIN; TIME;

AMINO ACID SEQUENCE; KINETICS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN UNFOLDING; SRC HOMOLOGY DOMAINS; TIME FACTORS; UREA; WATER;

EID: 84902982286     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp410019f     Document Type: Article

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