Toward an atomistic description of the urea-denatured state of proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 15, 2013, Pages 5933-5938

  Candotti, Michela ^a,b   Esteban Martín, Santiago ^a,b   Salvatella, Xavier ^a,b,c   Orozco, Modesto ^a,b,d  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b BARCELONA SUPERCOMPUTING CENTER   (Spain)

^c INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Denaturing mechanism; Ensemble simulation; Protein unfolding; Random coil

Indexed keywords

UBIQUITIN; UREA;

ARTICLE; HYDROGEN BOND; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN REFOLDING; PROTEIN UNFOLDING; X RAY CRYSTALLOGRAPHY;

COMPUTER SIMULATION; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SCATTERING, RADIATION; SOLVENTS; TIME FACTORS; UBIQUITIN; UREA; WATER; X-RAYS;

EID: 84876065228     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1216589110     Document Type: Article

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