Collapse of unfolded proteins in a mixture of denaturants

Journal of the American Chemical Society

Volumn 134, Issue 44, 2012, Pages 18266-18274

  Xia, Zhen ^a,c   Das, Payel ^a   Shakhnovich, Eugene I ^b   Zhou, Ruhong ^a,d  

^a IBM T J WATSON RESEARCH CENTER   (United States)

^b HARVARD UNIVERSITY   (United States)

^c The University of Texas at Austin   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMISTIC MOLECULAR DYNAMICS SIMULATIONS; COLLAPSE TRANSITIONS; CONFORMATIONAL ENSEMBLE; DENATURED PROTEINS; DENATURED STATE; GUANIDINIUM CHLORIDES; HEN EGG WHITE LYSOZYME; HYDROPHOBIC RESIDUES; LOCAL ENVIRONMENTS; MOLECULAR SIMULATIONS; NON-NATIVE; NON-NATIVE INTERACTIONS; PROTEIN COLLAPSE; PROTEIN DENATURANT; PROTEIN SURFACE; SELF-INTERACTIONS; SOLVATION SHELL; UNFOLDED PROTEINS;

CHLORINE COMPOUNDS; CONFORMATIONS; HYDROPHOBICITY; METABOLISM; MIXTURES; STATISTICAL MECHANICS; UREA;

PROTEINS;

GUANIDINE; LYSOZYME; UREA;

ARTICLE; DENATURATION; HYDROPHOBICITY; MOLECULAR DYNAMICS; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN INTERACTION; SIMULATION; SOLUBILITY; STATIC ELECTRICITY; UNFOLDED PROTEIN RESPONSE;

ANIMALS; BACTERIAL PROTEINS; CHICKENS; DNA-BINDING PROTEINS; GUANIDINE; MODELS, MOLECULAR; MURAMIDASE; PEPTOCOCCUS; PROTEIN CONFORMATION; PROTEIN UNFOLDING; UREA;

EID: 84868587589     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3031505     Document Type: Article

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