Activated T Cells Secrete an Alternatively Spliced Form of Common γ-Chain that Inhibits Cytokine Signaling and Exacerbates Inflammation

Immunity

Volumn 40, Issue 6, 2014, Pages 910-923

  Hong, Changwan ^a,e   Luckey, Megan A ^a   Ligons, Davinna L ^a   Waickman, Adam T ^a   Park, Joo Young ^a   Kim, Grace Y ^a   Keller, Hilary R ^a   Etzensperger, Ruth ^a   Tai, Xuguang ^a   Lazarevic, Vanja ^a   Feigenbaum, Lionel ^b   Catalfamo, Marta ^c   Walsh, Scott T R ^d   Park, Jung Hyun ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d UNIVERSITY OF MARYLAND   (United States)

^e Pusan National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 2 RECEPTOR GAMMA; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; DISEASE SEVERITY; EXTRACELLULAR MATRIX; IMMUNOREGULATION; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SECRETION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL;

ALTERNATIVE SPLICING; ANIMALS; AUTOIMMUNITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNOGLOBULIN GAMMA-CHAINS; IMMUNOMODULATION; INFLAMMATION; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; INTERLEUKIN-5 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BINDING; PROTEIN ISOFORMS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TH17 CELLS;

EID: 84902676037     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.04.020     Document Type: Article

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