Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 19, 2013, Pages

  Lundström, Wangko ^a,b   Highfill, Steven ^a   Walsh, Scott T R ^c,d   Beq, Stephanie ^e   Morse, Elizabeth ^a   Kockum, Ingrid ^b   Alfredsson, Lars ^b   Olsson, Tomas ^b   Hillert, Jan ^b   Mackall, Crystal L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c Bldg 142   (United States)

^d UNIVERSITY OF MARYLAND   (United States)

^e Cytheris SA   (France)

Author keywords

Immunology; Soluble receptors; Tolerance

Indexed keywords

FAS ANTIGEN; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; MESSENGER RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1; THYMIC STROMAL LYMPHOPOIETIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNITY; CELL SURVIVAL; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; GENETIC SUSCEPTIBILITY; GENOTYPE; HOMEOSTASIS; HUMAN; HUMAN CELL; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RNA SPLICING; SIGNAL TRANSDUCTION; SYSTEMATIC REVIEW;

IMMUNOLOGY; SOLUBLE RECEPTORS; TOLERANCE;

ADOLESCENT; ADULT; AGED; ANIMALS; AUTOIMMUNITY; CELL LINE; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENOTYPE; HUMANS; INTERLEUKIN-7; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; MULTIPLE SCLEROSIS; POLYMORPHISM, GENETIC; RECEPTORS, INTERLEUKIN-7; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84877327394     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222303110     Document Type: Article

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