Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

Journal of Experimental Medicine

Volumn 209, Issue 12, 2012, Pages 2263-2276

  McCaughtry, Tom M ^a,e   Etzensperger, Ruth ^a   Alag, Amala ^a   Tai, Xuguang ^a   Kurtulus, Sema ^b,f   Park, Jung Hyun ^a   Grinberg, Alex ^c   Love, Paul ^c   Feigenbaum, Lionel ^d   Erman, Batu ^b   Singer, Alfred ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SABANCI UNIVERSITY   (Turkey)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d SAIC FREDERICK INC   (United States)

^e MEDIMMUNE   (United States)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 17 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RUNX3; TRANSCRIPTION FACTOR RUNX3D; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FATE; CELL LINEAGE; CELL MATURATION; CELL SURVIVAL; FEMALE; GENE DELETION; GENE EXPRESSION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS; TRANSCRIPTION INITIATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; FLOW CYTOMETRY; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-7; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CYTOKINE; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-7; THYMUS GLAND;

EID: 84871899512     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121505     Document Type: Article

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