-
1
-
-
33846632842
-
Interleukin-7 receptor expression: Intelligent design
-
DOI 10.1038/nri2023, PII NRI2023
-
Mazzucchelli R, Durum SK (2007) Interleukin-7 receptor expression: Intelligent design. Nat Rev Immunol 7(2):144-154. (Pubitemid 46178275)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.2
, pp. 144-154
-
-
Mazzucchelli, R.1
Durum, S.K.2
-
2
-
-
0037119351
-
Cytokine and cytokine receptor pleiotropy and redundancy
-
DOI 10.1074/jbc.R200003200
-
Ozaki K, Leonard WJ (2002) Cytokine and cytokine receptor pleiotropy and redundancy. J Biol Chem 277:29355-29358. (Pubitemid 41079217)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.33
, pp. 29355-29358
-
-
Ozaki, K.1
Leonard, W.J.2
-
3
-
-
9644295710
-
c-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
-
DOI 10.1111/j.0105-2896.2004.00203.x
-
Kovanen PE, Leonard WJ (2004) Cytokines and immunodeficiency diseases: Critical roles of the γ(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol Rev 202(1):67-83. (Pubitemid 39576905)
-
(2004)
Immunological Reviews
, vol.202
, pp. 67-83
-
-
Kovanen, P.E.1
Leonard, W.J.2
-
4
-
-
0032472838
-
Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa
-
DOI 10.1084/jem.187.3.389
-
Watanabe M, et al. (1998) Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa. J Exp Med 187: 389-402. (Pubitemid 28080068)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.3
, pp. 389-402
-
-
Watanabe, M.1
Ueno, Y.2
Yajima, T.3
Okamoto, S.4
Hayashi, T.5
Yamazaki, M.6
Iwao, Y.7
Ishii, H.8
Habu, S.9
Uehira, M.10
Nishimoto, H.11
Ishikawa, H.12
Hata, J.-I.13
Hibi, T.14
-
5
-
-
34548351247
-
Interleukin 7 receptor α chain (IL7R) shows allelic and functional association with multiple sclerosis
-
DOI 10.1038/ng2103, PII NG2103
-
Gregory SG, et al.; Multiple Sclerosis Genetics Group (2007) Interleukin 7 receptor αchain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 39:1083-1091. (Pubitemid 47340652)
-
(2007)
Nature Genetics
, vol.39
, Issue.9
, pp. 1083-1091
-
-
Gregory, S.G.1
Schmidt, S.2
Seth, P.3
Oksenberg, J.R.4
Hart, J.5
Prokop, A.6
Caillier, S.J.7
Ban, M.8
Goris, A.9
Barcellos, L.F.10
Lincoln, R.11
McCauley, J.L.12
Sawcer, S.J.13
Compston, D.A.S.14
Dubois, B.15
Hauser, S.L.16
Garcia-Blanco, M.A.17
Pericak-Vance, M.A.18
Haines, J.L.19
-
6
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
DOI 10.1056/NEJMoa073493
-
Hafler DA, et al.; International Multiple Sclerosis Genetics Consortium (2007) Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357: 851-862. (Pubitemid 47347319)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.9
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
De Bakker, P.I.W.7
Gabriel, S.B.8
Mirel, D.B.9
Ivinson, A.J.10
Pericak-Vance, M.A.11
Gregory, S.G.12
Rioux, J.D.13
McCauley, J.L.14
Haines, J.L.15
Barcellos, L.F.16
Cree, B.17
Oksenberg, J.R.18
Hauser, S.L.19
-
7
-
-
0035469821
-
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by downregulating the cyclin-dependent kinase inhibitor p27(kip1)
-
Barata JT, Cardoso AA, Nadler LM, Boussiotis VA (2001) Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by downregulating the cyclin-dependent kinase inhibitor p27(kip1). Blood 98:1524-1531.
-
(2001)
Blood
, vol.98
, pp. 1524-1531
-
-
Barata, J.T.1
Cardoso, A.A.2
Nadler, L.M.3
Boussiotis, V.A.4
-
8
-
-
80053385665
-
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
-
Zenatti PP, et al. (2011) Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia. Nat Genet 43:932-939.
-
(2011)
Nat Genet
, vol.43
, pp. 932-939
-
-
Zenatti, P.P.1
-
9
-
-
67649876115
-
New insights into the regulation of T cells by γ(c) family cytokines
-
Rochman Y, Spolski R, Leonard WJ (2009) New insights into the regulation of T cells by γ(c) family cytokines. Nat Rev Immunol 9:480-490.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 480-490
-
-
Rochman, Y.1
Spolski, R.2
Leonard, W.J.3
-
10
-
-
0025350049
-
Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily
-
Goodwin RG, et al. (1990) Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily. Cell 60:941-951.
-
(1990)
Cell
, vol.60
, pp. 941-951
-
-
Goodwin, R.G.1
-
11
-
-
0030050701
-
Binding in the growth hormone receptor complex
-
Wells JA (1996) Binding in the growth hormone receptor complex. Proc Natl Acad Sci USA 93(1):1-6.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.1
, pp. 1-6
-
-
Wells, J.A.1
-
12
-
-
67649158212
-
Identification and biochemical characterization of human plasma soluble IL-7R: Lower concentrations in HIV-1-infected patients
-
Rose T, Lambotte O, Pallier C, Delfraissy JF, Colle JH (2009) Identification and biochemical characterization of human plasma soluble IL-7R: Lower concentrations in HIV-1-infected patients. J Immunol 182:7389-7397.
-
(2009)
J Immunol
, vol.182
, pp. 7389-7397
-
-
Rose, T.1
Lambotte, O.2
Pallier, C.3
Delfraissy, J.F.4
Colle, J.H.5
-
13
-
-
77952033674
-
Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response
-
Rose T, et al. (2010) Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response. J Biol Chem 285:14898-14908.
-
(2010)
J Biol Chem
, vol.285
, pp. 14898-14908
-
-
Rose, T.1
-
14
-
-
77958498185
-
IL-2 induces conformational changes in its preassembled receptor core, which then migrates in lipid raft and binds to the cytoskeleton meshwork
-
Pillet AH, et al. (2010) IL-2 induces conformational changes in its preassembled receptor core, which then migrates in lipid raft and binds to the cytoskeleton meshwork. J Mol Biol 403:671-692.
-
(2010)
J Mol Biol
, vol.403
, pp. 671-692
-
-
Pillet, A.H.1
-
15
-
-
0029796365
-
Homodimerization of interleukin-4 receptor α chain can induce intracellular signaling
-
Kammer W, et al. (1996) Homodimerization of interleukin-4 receptor α chain can induce intracellular signaling. J Biol Chem 271:23634-23637.
-
(1996)
J Biol Chem
, vol.271
, pp. 23634-23637
-
-
Kammer, W.1
-
16
-
-
57749119532
-
Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the γ chain
-
Malka Y, et al. (2008) Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the γ chain. J Biol Chem 283: 33569-33577.
-
(2008)
J Biol Chem
, vol.283
, pp. 33569-33577
-
-
Malka, Y.1
-
17
-
-
0025633003
-
Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity
-
Yoshimura A, Longmore G, Lodish HF (1990) Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity. Nature 348:647-649. (Pubitemid 120015129)
-
(1990)
Nature
, vol.348
, Issue.6302
, pp. 647-649
-
-
Yoshimura, A.1
Longmore, G.2
Lodish, H.F.3
-
18
-
-
77955334994
-
Cytokine-receptor interactions as drug targets
-
Schreiber G, Walter MR (2010) Cytokine-receptor interactions as drug targets. Curr Opin Chem Biol 14:511-519.
-
(2010)
Curr Opin Chem Biol
, vol.14
, pp. 511-519
-
-
Schreiber, G.1
Walter, M.R.2
-
19
-
-
58149193349
-
Structural and biophysical studies of the human IL-7/IL-7Rα complex
-
McElroy CA, Dohm JA, Walsh ST (2009) Structural and biophysical studies of the human IL-7/IL-7Rα complex. Structure 17:54-65.
-
(2009)
Structure
, vol.17
, pp. 54-65
-
-
McElroy, C.A.1
Dohm, J.A.2
Walsh, S.T.3
-
20
-
-
27944505913
-
c receptors
-
DOI 10.1126/science.1117893
-
Wang X, Rickert M, Garcia KC (2005) Structure of the quaternary complex of interleukin-2 with its α, β, and γc receptors. Science 310:1159-1163. (Pubitemid 41681737)
-
(2005)
Science
, vol.310
, Issue.5751
, pp. 1159-1163
-
-
Wang, X.1
Rickert, M.2
Garcia, K.C.3
-
21
-
-
0033548259
-
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation
-
Livnah O, et al. (1999) Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science 283:987-990.
-
(1999)
Science
, vol.283
, pp. 987-990
-
-
Livnah, O.1
-
22
-
-
0033574713
-
Crystal structure of the interleukin-4/receptor α chain complex reveals a mosaic binding interface
-
Hage T, Sebald W, Reinemer P (1999) Crystal structure of the interleukin-4/receptor αchain complex reveals a mosaic binding interface. Cell 97:271-281. (Pubitemid 29194277)
-
(1999)
Cell
, vol.97
, Issue.2
, pp. 271-281
-
-
Hage, T.1
Sebald, W.2
Reinemer, P.3
-
23
-
-
38649137731
-
Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System
-
DOI 10.1016/j.cell.2007.12.030, PII S0092867408000470
-
LaPorte SL, et al. (2008) Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell 132:259-272. (Pubitemid 351172435)
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 259-272
-
-
LaPorte, S.L.1
Juo, Z.S.2
Vaclavikova, J.3
Colf, L.A.4
Qi, X.5
Heller, N.M.6
Keegan, A.D.7
Garcia, K.C.8
-
24
-
-
34848820556
-
Crystallization and preliminary X-ray diffraction of human interleukin-7 bound to unglycosylated and glycosylated forms of its α-receptor
-
Wickham J, Jr., Walsh ST (2007) Crystallization and preliminary X-ray diffraction of human interleukin-7 bound to unglycosylated and glycosylated forms of its α-receptor. Acta Crystallogr Sect F Struct Biol Cryst Commun 63:865-869.
-
(2007)
Acta Crystallogr Sect F Struct Biol Cryst Commun
, vol.63
, pp. 865-869
-
-
Wickham Jr., J.1
Walsh, S.T.2
-
26
-
-
0038265184
-
2 receptor
-
DOI 10.1074/jbc.M301757200
-
Rose T, Moreau JL, Eckenberg R, Thèze J (2003) Structural analysis and modeling of a synthetic interleukin-2 mimetic and its interleukin-2Rβ2 receptor. J Biol Chem 278: 22868-22876. (Pubitemid 36830350)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22868-22876
-
-
Rose, T.1
Moreau, J.-L.2
Eckenberg, R.3
Theze, J.4
-
27
-
-
55749094535
-
Human IL-Rβ chains form IL-2 binding homodimers
-
Pillet AH, et al. (2008) Human IL-Rβ chains form IL-2 binding homodimers. Eur Cytokine Netw 19(1):49-59.
-
(2008)
Eur Cytokine Netw
, vol.19
, Issue.1
, pp. 49-59
-
-
Pillet, A.H.1
-
28
-
-
0034650902
-
Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein
-
DOI 10.1016/S0969-2126(00)00081-2
-
Deivanayagam CC, et al. (2000) Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein. Structure 8(1):67-78. (Pubitemid 30051343)
-
(2000)
Structure
, vol.8
, Issue.1
, pp. 67-78
-
-
Deivanayagam, C.C.S.1
Rich, R.L.2
Carson, M.3
Owens, R.T.4
Danthuluri, S.5
Bice, T.6
Hook, M.7
Narayana, S.V.L.8
-
29
-
-
33644540157
-
Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor
-
Stauber DJ, et al. (2006) Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci USA 103:2788-2793.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2788-2793
-
-
Stauber, D.J.1
-
30
-
-
26944493862
-
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
-
DOI 10.1038/nsmb977, PII NSMB977
-
Brown RJ, et al. (2005) Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nat Struct Mol Biol 12:814-821. (Pubitemid 43086257)
-
(2005)
Nature Structural and Molecular Biology
, vol.12
, Issue.9
, pp. 814-821
-
-
Brown, R.J.1
Adams, J.J.2
Pelekanos, R.A.3
Wan, Y.4
McKinstry, W.J.5
Palethorpe, K.6
Seeber, R.M.7
Monks, T.A.8
Eidne, K.A.9
Parke, M.W.10
Waters, M.J.11
-
31
-
-
0033548048
-
Erythropoietin receptor activation by a ligand-induced conformation change
-
Remy I, Wilson IA, Michnick SW (1999) Erythropoietin receptor activation by a ligand-induced conformation change. Science 283:990-993.
-
(1999)
Science
, vol.283
, pp. 990-993
-
-
Remy, I.1
Wilson, I.A.2
Michnick, S.W.3
-
32
-
-
79956108320
-
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias
-
Shochat C, et al. (2011) Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias. J Exp Med 208:901-908.
-
(2011)
J Exp Med
, vol.208
, pp. 901-908
-
-
Shochat, C.1
-
33
-
-
33846399142
-
z, a Depth-dependent Potential for Assessing the Energies of Insertion of Amino Acid Side-chains into Membranes: Derivation and Applications to Determining the Orientation of Transmembrane and Interfacial Helices
-
DOI 10.1016/j.jmb.2006.09.020, PII S0022283606012095
-
Senes A, et al. (2007) E(z), a depth-dependent potential for assessing the energies of insertion of amino acid side-chains into membranes: Derivation and applications to determining the orientation of transmembrane and interfacial helices. J Mol Biol 366: 436-448. (Pubitemid 46136195)
-
(2007)
Journal of Molecular Biology
, vol.366
, Issue.2
, pp. 436-448
-
-
Senes, A.1
Chadi, D.C.2
Law, P.B.3
Walters, R.F.S.4
Nanda, V.5
DeGrado, W.F.6
-
34
-
-
76249096219
-
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
-
Yoda A, et al. (2010) Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia. Proc Natl Acad Sci USA 107:252-257.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 252-257
-
-
Yoda, A.1
-
35
-
-
0035836645
-
Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain
-
DOI 10.1073/pnas.081069198
-
Constantinescu SN, et al. (2001) Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain. Proc Natl Acad Sci USA 98:4379-4384. (Pubitemid 32294985)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.8
, pp. 4379-4384
-
-
Constantinescu, S.N.1
Keren, T.2
Socolovsky, M.3
Nam, H.-S.4
Henis, Y.I.5
Lodish, H.F.6
-
36
-
-
33646381647
-
Active conformation of the erythropoietin receptor: Random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains
-
DOI 10.1074/jbc.M512638200
-
Lu X, Gross AW, Lodish HF (2006) Active conformation of the erythropoietin receptor: Random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains. J Biol Chem 281:7002-7011. (Pubitemid 43847463)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.11
, pp. 7002-7011
-
-
Lu, X.1
Gross, A.W.2
Lodish, H.F.3
-
37
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
Lemmon MA, Schlessinger J (2010) Cell signaling by receptor tyrosine kinases. Cell 141:1117-1134.
-
(2010)
Cell
, vol.141
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
38
-
-
0030041323
-
Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: One high-affinity and one low-affinity interaction
-
DOI 10.1021/bi9524272
-
Philo JS, Aoki KH, Arakawa T, Narhi LO, Wen J (1996) Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: One high-affinity and one lowaffinity interaction. Biochemistry 35:1681-1691. (Pubitemid 26055303)
-
(1996)
Biochemistry
, vol.35
, Issue.5
, pp. 1681-1691
-
-
Philo, J.S.1
Aoki, K.H.2
Arakawa, T.3
Narhi, L.O.4
Wen, J.5
-
40
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brünger AT, et al. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54: 905-921.
-
(1998)
Acta Crystallogr D Biol Crystallogr
, vol.54
, pp. 905-921
-
-
Brünger, A.T.1
|