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Volumn 82, Issue , 2014, Pages 480-489
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Synthesis, antibacterial and antitubercular activities of benzimidazole bearing substituted 2-pyridone motifs
a
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Author keywords
2 Pyridone; Antibacterial activity; Antitubercular activity; Benzimidazole; Cytotoxicity; MABA assay
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Indexed keywords
1 ((1 (1H BENZO[D] IMIDAZOL 2 YL)ETHYLIDENE) AMINO) 6 AMINO 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((2 METHYLBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((2CHLOROBENZYLIDENE)AMINO) 6 ((2CHLOROBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((2HYDROXYBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((3 BROMOBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((3 CHLOROBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((3 HYDROXYBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((3 METHYLBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((3 NITROBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((3FLUOROBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4 BROMOBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4 FLUOROBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4 HYDROXYBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4 METHOXYBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4CHLOROBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4METHYLBENZYLIDENE)AMINO) 4 (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((4NITROBENZYLIDENE)AMINO) (4 NITROPHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 ((ARYLBENZYLIDENE)AMINO) 4 (4NITROPHENYL) 2 OXO 1,2 DIHYDRO PYRIDINE 3,5 DICARBONITRILE;
1 ((1 (1H BENZO[D]IMIDAZOL 2 YL)ETHYLIDENE)AMINO) 6 (BENZYLIDENEAMINO) 4 (4 NITRO PHENYL) 2 OXO 1,2 DIHYDROPYRIDINE 3,5 DICARBONITRILE;
2 PYRIDONE DERIVATIVE;
BENZIMIDAZOLE DERIVATIVE;
CARBONYL DERIVATIVE;
N' (1 (1H BENZO[D] IMIDAZOL 2 YL)ETHYLIDENE) 2 CYANOACETOHYDRAZIDE;
TUBERCULOSTATIC AGENT;
UNCLASSIFIED DRUG;
2-HYDROXYPYRIDINE;
ANTIINFECTIVE AGENT;
BENZIMIDAZOLE;
PYRIDONE DERIVATIVE;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
BACTERIAL GROWTH;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG BIOAVAILABILITY;
DRUG POTENCY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG SYNTHESIS;
GRAM NEGATIVE BACTERIUM;
GRAM POSITIVE BACTERIUM;
IN VITRO STUDY;
LIPOPHILICITY;
MINIMUM INHIBITORY CONCENTRATION;
STRUCTURE ACTIVITY RELATION;
VERO CELL LINE;
ANIMAL;
BACTERIA;
CELL PROLIFERATION;
CHEMICAL STRUCTURE;
CHEMISTRY;
CHLOROCEBUS AETHIOPS;
DOSE RESPONSE;
DRUG EFFECTS;
GROWTH, DEVELOPMENT AND AGING;
MICROBIAL SENSITIVITY TEST;
SYNTHESIS;
ANIMALS;
ANTI-BACTERIAL AGENTS;
BACTERIA;
BENZIMIDAZOLES;
CELL PROLIFERATION;
CERCOPITHECUS AETHIOPS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
MICROBIAL SENSITIVITY TESTS;
MOLECULAR STRUCTURE;
PYRIDONES;
STRUCTURE-ACTIVITY RELATIONSHIP;
VERO CELLS;
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EID: 84902664264
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2014.06.004 Document Type: Article |
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Times cited : (65)
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References (37)
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