The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENs

G3: Genes, Genomes, Genetics

Volumn 4, Issue 6, 2014, Pages 1155-1165

  Kleinstiver, Benjamin P ^a,d   Wang, Li ^b   Wolfs, Jason M ^a   Kolaczyk, Tomasz ^a   McDowell, Brendon ^a   Wang, Xu ^c   Schild Poulter, Caroline ^a,c   Bogdanove, Adam J ^a,b   Edgell, David R ^a,b  

^a WESTERN UNIVERSITY   (Canada)

^b Department of Obstetrics Gynecology   (United States)

^c ROBARTS RESEARCH INSTITUTE   (Canada)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Genome editing; GIY YIG nuclease; I TevI; Monomeric TALEN; TAL effector

Indexed keywords

ENDONUCLEASE; NUCLEASE; NUCLEOTIDE; SPACER DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION LIKE ACTIVATOR EFFECTOR NUCLEASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; HUMAN; HUMAN CELL; IN VITRO STUDY; MUTAGENIC ACTIVITY; NONHUMAN; NUCLEOTIDE MOTIF; YEAST;

EID: 84902595538     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.114.011445     Document Type: Article

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