메뉴 건너뛰기




Volumn 7, Issue 4, 2014, Pages 916-928

Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC REACTION; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CD24+ CD25+ CD127- FOXP3+ REGULATORY T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELL FUNCTION; CELL POPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; FUNGUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; ASPERGILLUS; CELL CULTURE; COMPLICATION; CYSTIC FIBROSIS; HYPERSENSITIVITY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; METABOLISM; MICROBIOLOGY; MUCOSA; PHENOTYPE;

EID: 84902595275     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2013.107     Document Type: Article
Times cited : (100)

References (51)
  • 1
    • 84859390119 scopus 로고    scopus 로고
    • Induced CD4+Foxp3+ regulatory T cells in immune tolerance
    • Bilate, A.M. & Lafaille, J.J. Induced CD4+Foxp3+ regulatory T cells in immune tolerance. Annu. Rev. Immunol. 30, 733-758 (2012
    • (2012) Annu. Rev. Immunol , vol.30 , pp. 733-758
    • Bilate, A.M.1    Lafaille, J.J.2
  • 2
    • 84877742439 scopus 로고    scopus 로고
    • Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
    • Cebula, A., Seweryn, M., Rempala, G.A., Pabla, S.S., McIndoe, R.A. & Denning, T.L. et al. Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota. Nature 497, 258-262 (2013
    • (2013) Nature , vol.497 , pp. 258-262
    • Cebula, A.1    Seweryn, M.2    Rempala, G.A.3    Pabla, S.S.4    McIndoe, R.A.5    Denning, T.L.6
  • 3
    • 46749126890 scopus 로고    scopus 로고
    • Adaptive Foxp3+ regulatory Tcell-dependent and -independent control of allergic inflammation
    • Curotto de Lafaille, M.A., Kutchukhidze, N., Shen, S., Ding, Y., Yee, H. & Lafaille, J.J. Adaptive Foxp3+ regulatory Tcell-dependent and -independent control of allergic inflammation. Immunity 29, 114-126 (2008
    • (2008) Immunity , vol.29 , pp. 114-126
    • Curotto De Lafaille, M.A.1    Kutchukhidze, N.2    Shen, S.3    Ding, Y.4    Yee, H.5    Lafaille, J.J.6
  • 4
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?
    • Curotto de Lafaille, M.A. & Lafaille, J.J. Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?. Immunity 30, 626-635 (2009
    • (2009) Immunity , vol.30 , pp. 626-635
    • Curotto De Lafaille, M.A.1    Lafaille, J.J.2
  • 5
    • 84862777225 scopus 로고    scopus 로고
    • Extrathymically generated regulatory T cells control mucosal TH2 inflammation
    • Josefowicz, S.Z., Niec, R.E., Kim, H.Y., Treuting, P., Chinen, T. & Zheng, Y. et al. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 482, 395-399 (2012
    • (2012) Nature , vol.482 , pp. 395-399
    • Josefowicz, S.Z.1    Niec, R.E.2    Kim, H.Y.3    Treuting, P.4    Chinen, T.5    Zheng, Y.6
  • 6
    • 80054020840 scopus 로고    scopus 로고
    • Peripheral education of the immune system by colonic commensal microbiota
    • Lathrop, S.K.,Bloom,S.M., Rao, S.M.,Nutsch, K., Lio,C.W. & Santacruz, N. et al. Peripheral education of the immune system by colonic commensal microbiota. Nature 478, 250-254 (2011
    • (2011) Nature , vol.478 , pp. 250-254
    • Lathrop, S.K.1    Bloom, S.M.2    Rao, S.M.3    Nutsch Lio, C.W.4    Santacruz, N.5
  • 7
    • 84881023853 scopus 로고    scopus 로고
    • Flow-cytometric analysis of rare antigen-specific T cells
    • Bacher, P. & Scheffold, A. Flow-cytometric analysis of rare antigen-specific T cells. Cytometry A 83, 692-701 (2013
    • (2013) Cytometry A , vol.83 , pp. 692-701
    • Bacher, P.1    Scheffold, A.2
  • 9
    • 27944450041 scopus 로고    scopus 로고
    • Systemic fungal infections caused by Aspergillus species: Epidemiology, infection process and virulence determinants
    • Brakhage, A.A. Systemic fungal infections caused by Aspergillus species: Epidemiology, infection process and virulence determinants. Curr. Drug Targets 6, 875-886 (2005
    • (2005) Curr. Drug Targets , vol.6 , pp. 875-886
    • Brakhage, A.A.1
  • 11
    • 84861964286 scopus 로고    scopus 로고
    • Interactions between commensal fungi and the C-Type lectin receptor Dectin-1 influence colitis
    • Iliev, I.D., Funari, V.A., Taylor, K.D., Nguyen, Q., Reyes, C.N. & Strom, S.P. et al. Interactions between commensal fungi and the C-Type lectin receptor Dectin-1 influence colitis. Science 336, 1314-1317 (2012
    • (2012) Science , vol.336 , pp. 1314-1317
    • Iliev, I.D.1    Funari, V.A.2    Taylor, K.D.3    Nguyen, Q.4    Reyes, C.N.5    Strom, S.P.6
  • 12
    • 84055193570 scopus 로고    scopus 로고
    • Invasive mycoses: Strategies for effective management
    • 1 Suppl
    • Kontoyiannis, D.P. Invasive mycoses: Strategies for effective management. Am. J. Med. 125 (1 Suppl), S25-S38 (2012
    • (2012) Am. J. Med , vol.125
    • Kontoyiannis, D.P.1
  • 13
    • 79959269910 scopus 로고    scopus 로고
    • Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosis
    • Knutsen, A.P. & Slavin, R.G. Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosis. Clin. Dev. Immunol. 2011, 843763 (2011
    • (2011) Clin. Dev. Immunol , vol.2011 , pp. 843763
    • Knutsen, A.P.1    Slavin, R.G.2
  • 16
    • 79953163170 scopus 로고    scopus 로고
    • Immunity to fungal infections
    • Romani, L. Immunity to fungal infections. Nat. Rev. Immunol. 11, 275-288 (2011
    • (2011) Nat. Rev. Immunol , vol.11 , pp. 275-288
    • Romani, L.1
  • 18
    • 84875985733 scopus 로고    scopus 로고
    • Antigen-reactive T cell enrichment for direct, highresolution analysis of the human naive and memory Th cell repertoire
    • Bacher, P., Schink, C., Teutschbein, J., Kniemeyer, O., Assenmacher,M. & Brakhage, A.A. et al. Antigen-reactive T cell enrichment for direct, highresolution analysis of the human naive and memory Th cell repertoire. J. Immunol. 190, 3967-3976 (2013
    • (2013) J. Immunol , vol.190 , pp. 3967-3976
    • Bacher, P.1    Schink, C.2    Teutschbein, J.3    Kniemeyer, O.4    Assenmacher, M.5    Brakhage, A.A.6
  • 19
    • 84871124115 scopus 로고    scopus 로고
    • A converse 4-1BB and CD40 ligand expression pattern Delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+
    • Schoenbrunn, A., Frentsch,M., Kohler, S.,Keye, J.,Dooms,H. &Moewes,B. et al. A converse 4-1BB and CD40 ligand expression pattern Delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg. J. Immunol. 189, 5985-5994 (2012
    • (2012) Treg. J. Immunol , vol.189 , pp. 5985-5994
    • Schoenbrunn, A.1    Frentsch, M.2    Kohler, S.3    Keye, J.4    Dooms, H.5    Moewes, B.6
  • 20
    • 4644369302 scopus 로고    scopus 로고
    • Interleukin-2 is essential for CD4+CD25+ regulatory Tcell function
    • de la Rosa, M., Rutz, S., Dorninger, H. & Scheffold, A. Interleukin-2 is essential for CD4+CD25+ regulatory Tcell function. Eur. J. Immunol. 34, 2480-2488 (2004
    • (2004) Eur. J. Immunol , vol.34 , pp. 2480-2488
    • De La Rosa, M.1    Rutz, S.2    Dorninger, H.3    Scheffold, A.4
  • 21
    • 0037128660 scopus 로고    scopus 로고
    • Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
    • Kimmig, S., Przybylski, G.K., Schmidt, C.A., Laurisch, K., Mowes, B. & Radbruch, A. et al. Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195, 789-794 (2002
    • (2002) J. Exp. Med , vol.195 , pp. 789-794
    • Kimmig, S.1    Przybylski, G.K.2    Schmidt, C.A.3    Laurisch, K.4    Mowes, B.5    Radbruch, A.6
  • 22
    • 67650469829 scopus 로고    scopus 로고
    • Humannaive andmemory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells
    • Geiger, R.,Duhen, T., Lanzavecchia,A.& Sallusto, F.Humannaive andmemory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells. J. Exp. Med. 206, 1525-1534 (2009
    • (2009) J. Exp. Med , vol.206 , pp. 1525-1534
    • Geiger, R.1    Duhen, T.2    Lanzavecchia, A.3    Sallusto, F.4
  • 23
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid, Y., Piccirillo, C.A., Mendez, S., Shevach, E.M. & Sacks, D.L. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420, 502-507 (2002
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 24
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of hostmicroorganism interactions
    • Belkaid, Y. & Tarbell, K. Regulatory T cells in the control of hostmicroorganism interactions Annu. Rev. Immunol. 27, 551-589 (2009
    • (2009) Annu. Rev. Immunol , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 25
    • 84879604666 scopus 로고    scopus 로고
    • Pathogen-specific Treg cells expand early during Mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12
    • Shafiani, S., Dinh, C., Ertelt, J.M., Moguche, A.O., Siddiqui, I. & Smigiel, K.S. et al. Pathogen-specific Treg cells expand early during Mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity 38, 1261-1270 (2013
    • (2013) Immunity , vol.38 , pp. 1261-1270
    • Shafiani, S.1    Dinh, C.2    Ertelt, J.M.3    Moguche, A.O.4    Siddiqui, I.5    Smigiel, K.S.6
  • 26
  • 27
    • 77950500877 scopus 로고    scopus 로고
    • Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17T helper (Th17), cellular immunity
    • Chai, L.Y., van De Veerdonk, F.,Marijnissen, R.J., Cheng, S.C., Khoo, A.L. & Hectors, M. et al. Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17T helper (Th17), cellular immunity. Immunology 130, 46-54 (2010
    • (2010) Immunology , vol.130 , pp. 46-54
    • Chai, L.Y.1    Van De Veerdonk, F.2    Marijnissen, R.J.3    Cheng, S.C.4    Khoo, A.L.5    Hectors, M.6
  • 28
    • 77949506518 scopus 로고    scopus 로고
    • Healthy human T-Cell Responses to Aspergillus fumigatus antigens
    • Chaudhary,N., Staab, J.F. &Marr,K.A. Healthy human T-Cell Responses to Aspergillus fumigatus antigens. PLoS ONE 5, e9036 (2010
    • (2010) PLoS ONE , vol.5
    • Chaudhary, N.1    Staab, J.F.2    Marr, K.A.3
  • 29
    • 84860241847 scopus 로고    scopus 로고
    • Pathogen-inducedhumanth17cells produce ifn-gamma or il-10 and are regulated by il-1beta
    • Zielinski, C.E., Mele, F., Aschenbrenner, D., Jarrossay, D., Ronchi, F. & Gattorno, M.et al.Pathogen-inducedhumanTH17cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 484, 514-518 (2012
    • (2012) Nature , vol.484 , pp. 514-518
    • Zielinski, C.E.1    Mele, F.2    Aschenbrenner, D.3    Jarrossay, D.4    Ronchi, F.5    Gattorno, M.6
  • 30
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory t cells by indigenous clostridium species
    • Atarashi, K., Tanoue, T., Shima, T., Imaoka, A., Kuwahara, T. & Momose, Y. et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 331, 337-341 (2011
    • (2011) Science , vol.331 , pp. 337-341
    • Atarashi, K.1    Tanoue, T.2    Shima, T.3    Imaoka, A.4    Kuwahara, T.5    Momose, Y.6
  • 32
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy, K.J. & Powrie, F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 474, 298-306 (2011
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 33
    • 77954738601 scopus 로고    scopus 로고
    • Inducible foxp3+ regulatory t-cell development by a commensal bacterium of the intestinal microbiota
    • Round, J.L. & Mazmanian, S.K. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl. Acad. Sci. USA 107, 12204-12209 (2010
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 34
    • 78650906337 scopus 로고    scopus 로고
    • Coevolution of th1 th2, and th17 responses during repeated pulmonary exposure to aspergillus fumigatus conidia
    • Murdock, B.J., Shreiner, A.B., McDonald, R.A., Osterholzer, J.J., White, E.S. & Toews, G.B. et al. Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia. Infect. Immun. 79, 125-135 (2011
    • (2011) Infect. Immun , vol.79 , pp. 125-135
    • Murdock, B.J.1    Shreiner, A.B.2    McDonald, R.A.3    Osterholzer, J.J.4    White, E.S.5    Toews, G.B.6
  • 35
    • 84860244125 scopus 로고    scopus 로고
    • Interplay between Candida albicans and the mammalian innate host defense
    • Cheng, S.C., Joosten, L.A.,Kullberg, B.J. &Netea, M.G. Interplay between Candida albicans and the mammalian innate host defense. Infect. Immun. 80, 1304-1313 (2012
    • (2012) Infect. Immun , vol.80 , pp. 1304-1313
    • Cheng, S.C.1    Joosten, L.A.2    Kullberg, B.J.3    Netea, M.G.4
  • 36
    • 69349091586 scopus 로고    scopus 로고
    • Surface hydrophobin prevents immune recognition of airborne fungal spores
    • Aimanianda, V., Bayry, J., Bozza, S., Kniemeyer, O., Perruccio, K. & Elluru, S.R. et al. Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460, 1117-1121 (2009
    • (2009) Nature , vol.460 , pp. 1117-1121
    • Aimanianda, V.1    Bayry, J.2    Bozza, S.3    Kniemeyer, O.4    Perruccio, K.5    Elluru, S.R.6
  • 37
    • 77954161132 scopus 로고    scopus 로고
    • Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA
    • Bruns, S., Kniemeyer, O., Hasenberg, M., Aimanianda, V., Nietzsche, S. & Thywissen, A. et al. Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA. PLoS Pathog. 6, e1000873 (2010
    • (2010) PLoS Pathog , vol.6
    • Bruns, S.1    Kniemeyer, O.2    Hasenberg, M.3    Aimanianda, V.4    Nietzsche, S.5    Thywissen, A.6
  • 38
    • 77955391804 scopus 로고    scopus 로고
    • Tcr ligand density and affinity determine peripheral induction of foxp3 in vivo
    • Gottschalk, R.A., Corse, E. & Allison, J.P. TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J. Exp. Med. 207, 1701-1711 (2010
    • (2010) J. Exp. Med , vol.207 , pp. 1701-1711
    • Gottschalk, R.A.1    Corse, E.2    Allison, J.P.3
  • 39
    • 14644388075 scopus 로고    scopus 로고
    • Dominant tolerance: Activation thresholds for peripheral generation of regulatory T cells
    • Graca, L., Chen, T.C., LeMoine,A., Cobbold,S.P., Howie, D.&Waldmann, H. Dominant tolerance: Activation thresholds for peripheral generation of regulatory T cells. Trends Immunol. 26, 130-135 (2005
    • (2005) Trends Immunol , vol.26 , pp. 130-135
    • Graca, L.1    Chen, T.C.2    Le Moine, A.3    Cobbold, S.P.4    Howie, D.5    Waldmann, H.6
  • 41
    • 84878659255 scopus 로고    scopus 로고
    • Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance
    • Soroosh, P., Doherty, T.A., Duan, W., Mehta, A.K., Choi, H. & Adams, Y.F. et al. Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance. J. Exp. Med. 210, 775-788 (2013
    • (2013) J. Exp. Med , vol.210 , pp. 775-788
    • Soroosh, P.1    Doherty, T.A.2    Duan, W.3    Mehta, A.K.4    Choi, H.5    Adams, Y.F.6
  • 43
    • 65449141433 scopus 로고    scopus 로고
    • Loss of foxp3 expression in natural human cd4+cd25+ regulatory t cells upon repetitive in vitro stimulation
    • Hoffmann, P., Boeld, T.J., Eder, R., Huehn, J., Floess, S. & Wieczorek, G. et al. Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation. Eur. J. Immunol. 39, 1088-1097 (2009
    • (2009) Eur. J. Immunol , vol.39 , pp. 1088-1097
    • Hoffmann, P.1    Boeld, T.J.2    Eder, R.3    Huehn, J.4    Floess, S.5    Wieczorek, G.6
  • 44
    • 85006274138 scopus 로고    scopus 로고
    • Impact of Aspergillus fumigatus in allergic airway diseases
    • Chaudhary, N. & Marr, K.A. Impact of Aspergillus fumigatus in allergic airway diseases. Clin. Transl. Allergy 1, 4 (2011
    • (2011) Clin. Transl. Allergy , vol.1 , Issue.4
    • Chaudhary, N.1    Marr, K.A.2
  • 45
    • 84859508650 scopus 로고    scopus 로고
    • Defective phagocytosis in airways disease
    • Donnelly, L.E. & Barnes, P.J. Defective phagocytosis in airways disease. Chest 141, 1055-1062 (2012
    • (2012) Chest , vol.141 , pp. 1055-1062
    • Donnelly, L.E.1    Barnes, P.J.2
  • 46
    • 83755173097 scopus 로고    scopus 로고
    • Inducible cd4+ lap+foxp3- regulatory t cells suppress allergic inflammation
    • Duan, W., So, T., Mehta, A.K., Choi, H. & Croft, M. Inducible CD4+ LAP+Foxp3- regulatory T cells suppress allergic inflammation. J. Immunol. 187, 6499-6507 (2011
    • (2011) J. Immunol , vol.187 , pp. 6499-6507
    • Duan, W.1    So, T.2    Mehta, A.K.3    Choi, H.4    Croft, M.5
  • 47
    • 70049094943 scopus 로고    scopus 로고
    • Regulatory T cells in asthma
    • Lloyd, C.M. & Hawrylowicz, C.M. Regulatory T cells in asthma. Immunity 31, 438-449 (2009
    • (2009) Immunity , vol.31 , pp. 438-449
    • Lloyd, C.M.1    Hawrylowicz, C.M.2
  • 48
    • 3242754344 scopus 로고    scopus 로고
    • Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3
    • Ostroukhova, M., Seguin-Devaux, C., Oriss, T.B., Dixon-McCarthy, B., Yang, L. & Ameredes, B.T. et al. Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3. J. Clin. Invest. 114, 28-38 (2004
    • (2004) J. Clin. Invest , vol.114 , pp. 28-38
    • Ostroukhova, M.1    Seguin-Devaux, C.2    Oriss, T.B.3    Dixon-Mccarthy, B.4    Yang, L.5    Ameredes, B.T.6
  • 49
    • 66749154821 scopus 로고    scopus 로고
    • Allergic bronchopulmonary aspergillosis in a 2-year-old asthmatic boy with immune dysregulation, polyendocrinopathy, enteropathy, X-linked
    • Ohshima, M., Futamura, M., Kamachi, Y., Ito, K. & Sakamoto, T. Allergic bronchopulmonary aspergillosis in a 2-year-old asthmatic boy with immune dysregulation, polyendocrinopathy, enteropathy, X-linked. Pediatr. Pulmonol. 44, 297-299 (2009
    • (2009) Pediatr. Pulmonol , vol.44 , pp. 297-299
    • Ohshima, M.1    Futamura, M.2    Kamachi, Y.3    Ito, K.4    Sakamoto, T.5
  • 50
    • 0037114694 scopus 로고    scopus 로고
    • Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematologic malignancies
    • Hebart, H., Bollinger, C., Fisch, P., Sarfati, J., Meisner, C. & Baur, M. et al. Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematologic malignancies. Blood 100, 4521-4528 (2002
    • (2002) Blood , vol.100 , pp. 4521-4528
    • Hebart, H.1    Bollinger, C.2    Fisch, P.3    Sarfati, J.4    Meisner, C.5    Baur, M.6
  • 51
    • 58349116249 scopus 로고    scopus 로고
    • Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue
    • Wieczorek, G., Asemissen, A., Model, F., Turbachova, I., Floess, S. & Liebenberg, V. et al. Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Res 69, 599-608 (2009.
    • (2009) Cancer Res , vol.69 , pp. 599-608
    • Wieczorek, G.1    Asemissen, A.2    Model, F.3    Turbachova, I.4    Floess, S.5    Liebenberg, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.