ANTINEOPLASTIC ACTIVITY;
ANTIPROLIFERATIVE ACTIVITY;
ARTICLE;
BREAST CANCER CELL LINE;
CARBON NUCLEAR MAGNETIC RESONANCE;
CONTROLLED STUDY;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
IC50;
IN VITRO STUDY;
MCF 7 CELL LINE;
MOLECULAR DOCKING;
PROTON NUCLEAR MAGNETIC RESONANCE;
THIN LAYER CHROMATOGRAPHY;
CELL PROLIFERATION;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG DESIGN;
DRUG EFFECTS;
DRUG SCREENING;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
Available from http://www.who.int/gho/ncd/mortality-morbidity/cancer-text/en/index.html [last accessed 12 June 2013].
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Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein
Matsuo H, Wakasugi M, Takanaga H, et al. Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein. Contr Rel 2001;77:77-86.
Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity
(a) Marques SM, Enyedy EA, Supuran CT, et al. Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity. Bioorg Med Chem 2010;18:5081-9.
In vitro anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido[4,5-b]quinolines bearing a sulfonamide moiety
(b) Ghorab MM, Ragab FA, Heiba HI, et al. In vitro anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido[4,5-b]quinolines bearing a sulfonamide moiety. Med Chem Res 2011; 20:388-400.
In vitro anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido[4,5-b]quinolines bearing a sulfonamide moiety
(c) Ghorab MM, Ragab FA, Heiba HI, et al. In vitro anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido[4,5-b]quinolines bearing a sulfonamide moiety. Eur J Med Chem 2010;45:3677-84.
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes i and II, and transmembrane, tumor-associated isozyme IX
(d) Abbate F, Casini A, Owa T, et al. Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Bioorg Med Chem Lett 2004;14:217-23.
Synthesis and antiviral/antitumor evaluation of 2-amino-and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones
(e) Stephens CE, Felder TM, Sowell JW, et al. Synthesis and antiviral/antitumor evaluation of 2-amino-and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones. Bioorg Med Chem 2001;9:1123-32.
QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction
(a) Moorthy NS, Cerqueira NS, Ramos MJ, Fernandes PA. QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction. Med Chem Res 2012;21:133-44.
Role of the retinal vascular endothelial cell in ocular disease
(b) Bharadwaj AS, Appukuttan B, Wilmarth PA, et al. Role of the retinal vascular endothelial cell in ocular disease. Prog Retinal Eye Res 2013;32:102-80.
Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor-mediated pathway in MDA-MB-231 ER-negative breast cancer cells
(d) Lee EH, Oh SY, Sung MK. Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor-mediated pathway in MDA-MB-231 ER-negative breast cancer cells. Food Chem Tox 2012;50:4136-43.
Synthesis and anticancer activity of some new pyridine derivatives
(a) Bassyouni FA, Tawfik HA, Soliman AM, Abdel Rehim M. Synthesis and anticancer activity of some new pyridine derivatives. Res Chem Intermed 2012;38:1291-310.
Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives
(b) Amr AE, Mohamed AM, Mohamed SF, Abdel-Hafez NA, Hammam. Anticancer activities of some newly synthesized pyridine, pyrane, and pyrimidine derivatives. Bioorg Med Chem 2006;14:5481-8.
Synthesis of thiophene and NO-curcuminoids for antiinflammatory and anti-cancer activities
(a) Ahmed MM, Khan MA, Rainsford KD. Synthesis of thiophene and NO-curcuminoids for antiinflammatory and anti-cancer activities. Molecules 2013; 18:1483-501.
Synthesis of thiazolidine and thiophene derivatives for evaluation as anticancer agents
(b) El-Gaby MSA, Ismail ZH, Abdel-Gawad SM, et al. Synthesis of thiazolidine and thiophene derivatives for evaluation as anticancer agents. Phosphorous, sulfur and silicon 2009;184:2645-54.
Anticancer and radiosensitizing evaluation of some new pyranothiazole-Schiff bases bearing the biologically active sulfonamide moiety
(a) Ghorab MM, Shaaban MA, Refaat HM, et al. Anticancer and radiosensitizing evaluation of some new pyranothiazole-Schiff bases bearing the biologically active sulfonamide moiety. Eur J Med Chem 2012;53:403-7.
Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2
(b) Lu X, Liu X, Wan B, et al. Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. Eur J Med Chem 2012;49:164-71.
4-Aryl-4H-chromene-3-carbonitrile derivatives: Evaluation of Src kinase inhibitory and anticancer activities
(a) Fallah-Tafti A, Tiwari R, Shirazi AN, Akbarzadeh T, et al. 4-Aryl-4H-chromene-3-carbonitrile derivatives: evaluation of Src kinase inhibitory and anticancer activities. Med Chem 2011;7:466-72.
Dapson in heterocyclic chemistry, Part V: Synthesis, molecular docking and anticancer activity of some novel sulfonylbiscom-pounds carrying biologically active dihydropyridine, dihydroisoqui-noline, 1,3-dithiolan, 1,3-dithian, acrylamide, pyrazole, pyrazolopyrimidine and benzochromenemoieties
(b) Ghorab MM, Al-Said MS, Nissan YM. Dapson in heterocyclic chemistry, Part V: synthesis, molecular docking and anticancer activity of some novel sulfonylbiscom-pounds carrying biologically active dihydropyridine, dihydroisoqui-noline, 1,3-dithiolan, 1,3-dithian, acrylamide, pyrazole, pyrazolopyrimidine and benzochromenemoieties. Chem Pharm Bull 2012;60:1019-28.
Practical synthesis of tetrasubstituted thiophenes for use in compound libraries
Mckibben BP, Cartwright CH, Castelhano L. Practical synthesis of tetrasubstituted thiophenes for use in compound libraries. Tetrahedron Lett 1999;40:5471-4.
A novel cyclocondensation of xanthates containing active methylene groups with isothiocyanates. Spectral data and X-ray structures of the products
Tormos JV, Khodorkovsky YU, Neilands OY, Belyakov SV. A novel cyclocondensation of xanthates containing active methylene groups with isothiocyanates. Spectral data and X-ray structures of the products. Tetrahedron 1992;48:6863-74.
Synthesis of new iminocoumarins and their transformations into N-chloro and hydrazono compounds
Volmajer J, Toplak R, Leban I, Marechal AM. Synthesis of new iminocoumarins and their transformations into N-chloro and hydrazono compounds. Tetrahedron 2005;61:7012-21.
Sulfocoumarins (1,2-benzox-athiine-2,2-dioxides): A class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases
Tars K, Vullo D, Kazaks A, et al. Sulfocoumarins (1,2-benzox-athiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases. J Med Chem 2013;56:293-300.